Yuichiro Tamaki indicated the DPP’s decision to back the legislation would depend on if the ruling coalition accepts its alternative proposal.

Florist Yuichiro and trainee florist (and ex-con) Kaoru are going out together. But after six months, things aren’t making much progress – until Kaoru goes to someone’s aid and ends up without his wallet…

After the blood-sucking monsters killed his family when he was a child, Yuichiro vowed he wouldn’t stop fighting until every last one was dead.

Also: Kenny Ruiz, Risa Ebata, Keiichiro Saito, Yuichiro Fukushi, Reol, Lotus Juice, Ali, Nightmare, more

Yuichiro Tamaki, leader of the Japanese opposition Democratic Party for the People (DPP), said Wednesday that support for the government-submitted bill to cut

Amazon.com: ChaO [Blu-ray] : Various: Movies & TV

Associate Professor Nishioka Yūichirō of the Museum of Natural and Environmental History, Shizuoka (ふじのくに地球環境史ミュージアム), in Shizuoka City, Shizuoka Prefecture, and curator Andō Yūsuke of the Mizunami Fo...

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in mosquitoes.

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male #mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of #mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in #mosquitoes.

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in mosquitoes.

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in mosquitoes.

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in mosquitoes.

by YuMin M. Loh, Alberto J. Thornton, WenWei Loh, Tai-Ting Lee, Wan-Tze Chen, Yifeng Y. J. Xu, Jia Xin Yap, Yuichiro Tsuchiya, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi Male #mosquitoes locate females through strong and innate attraction to female flight sounds, the basis of mating in the world’s deadliest animal. In contrast, females do not show any sound attraction behaviors. Despite being documented for almost a century, the molecular underpinnings of these behavioral dimorphisms remain unknown. Here, we found that by disrupting the male-specific isoform of fruitless (referred to as fruM) in Aedes aegypti, fruM mutant males show complete abolition of sound attraction behaviors, resulting in failure of mutant males to locate females for mating. We identified strong fruitless expression in control male ears, with the loss of FruM severely disrupting mutant male ability to amplify female flight sounds. fruM mutant male ears also propagate frequency-specific, sound-evoked electrical signals at about one-sixth the magnitude of control males, significantly reducing the amount of auditory information relayed to the brain. fruitless thus plays a significant role in determining proper male peripheral hearing function underlying mating. Transcriptomic analyses of #mosquito ears identified essential hearing genes under the transcriptional influence of FruM via direct or indirect actions, thus shaping male-specific hearing cellular machineries that support male attraction to female flight sounds. Our work demonstrates that FruM commands male-specific hearing behaviors involved in mating by directly controlling the earliest stages of auditory organ performance, sound amplification and acoustic signal detection. Our findings show that FruM is essential for male-specific reproductive behaviors in #mosquitoes.

Industry leaders at TIFFCOM, the market for the Tokyo International Film Festival, said the new Japanese anime award planned for 2027 should highlight the people who make anime. The session was moderated by Fujitsu Ryota, programming consultant of the festival's animation department. Shimizu Akira, director of the Japan Animation Association (AJA), is the president and representative director of A-1 Pictures. He was joined by Saito Yuichiro, president of Studio Chizu, producer of “The Girl Who Leapt Through Time,” “Summer Wars” and “Wolf Children,” and Saito Masaya, chief executive of Toho's animation department and planning group leader.

Industry leaders at TIFFCOM, the market for the Tokyo International Film Festival, said the new Japanese anime award planned for 2027 should highlight the people who make anime. The session was moderated by Fujitsu Ryota, programming consultant of the festival's animation department. Shimizu Akira, director of the Japan Animation Association (AJA), is the president and representative director of A-1 Pictures. He was joined by Saito Yuichiro, president of Studio Chizu, producer of “The Girl Who Leapt Through Time,” “Summer Wars” and “Wolf Children,” and Saito Masaya, chief executive of Toho's animation department and planning group leader.

The new Japan Animation Awards planned for 2027 will highlight the people who create animation, industry leaders said at TIFFCOM, the Tokyo International Film Festival market. The session was moderated by Fujitsu Ryota, programming advisor for the festival's animation division. Akira Shimizu, director of the Japan Animation Association (AJA), is president and CEO of A-1 Pictures. Yuichiro Saito, president of Studio Cheese, who produced 'The Girl Who Leapt Through Time', 'Summer Wars', and 'Wolf Children', and Masaya Saito, general manager of Toho's animation division and leader of the planning group, joined.