Alexandre Serafim
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2210alex.bsky.social
Alexandre Serafim
@2210alex.bsky.social
570 followers 950 following 53 posts
Pediatric Intensivist at Brasilia, Brazil
Posts Replies Media Videos
Reposted by Alexandre Serafim
criticalcarereviews.com
Volatile anesthetic sedation in acute respiratory distress syndrome

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
October 5, 2026 at 8:25 PM
Reposted by Alexandre Serafim
gavinyamey.bsky.social
Essential, brilliant reporting by @by-cjewett.bsky.social

It's TERRIFYING: MAHA folks are INVESTIGATING pediatricians, who are some of the lowest paid docs in the professions, for vaccinating kids

It's part of a 20-year anti-vaxx campaign by RFK Jr "that some of his political allies have joined"
October 5, 2026 at 8:11 PM
Reposted by Alexandre Serafim
iwashyna.bsky.social
"Paired Spo2 measurements differed by ≥ 3% during 33% of monitored time (95% CI, 30%-35%) and by ≥ 5% during 13% of the time (95% CI, 12%-15%). The concordance correlation coefficient was 0.41, indicating poor agreement between paired Spo2 measurements."

www.chestcc.org/article/S294...
Discrepancy Between Peripheral Oxygen Saturation Measurements Obtained Simultaneously From 2 Pulse Oximeters Made by Different Manufacturers in Acutely Ill Patients
Among adults hospitalized with acute hypoxemia, Spo2 values measured simultaneously by 2 pulse oximeters from different manufacturers differed by a clinically meaningful amount approximately one-third...
www.chestcc.org
October 5, 2026 at 4:32 PM
Reposted by Alexandre Serafim
erictopol.bsky.social
In the new @science.org special issue on women's health, a 5★ review of menopause hormone therapy to promote healthy aging
science.org/doi/10.1126/...
Reframing menopause and menopause hormone therapy as opportunities for healthy aging
Menopause is an important biological transition with up to 72 symptoms that shapes aging trajectories across organs and encompasses ~40% of the female lifespan. Although menopause awareness is increas...
science.org
October 1, 2026 at 6:45 PM
Reposted by Alexandre Serafim
nejm.org
Duchenne muscular dystrophy, the most common childhood muscular dystrophy, with an estimated prevalence of 1 in 5000 boys 5 to 9 years of age, is a recessive degenerative disorder caused by variants in the dystrophin gene that lead to deficiency of dystrophin. Learn more: https://nej.md/4h7h0SP
An illustrated diagram of multisystem findings in patients with Duchenne Muscular Dystrophy. The image highlights physical features such as shoulder and arm positioning, a protruding belly, calf muscles with pseudohypertrophy, and a waddling gait. Annotations describe muscle weakness, respiratory challenges, positional deformity, and difficulty maintaining balance, leading to frequent falls.
October 1, 2026 at 7:00 PM
Reposted by Alexandre Serafim
atsblueeditor.bsky.social
Editorial: From mechanisms to clinical practice: introduction to an AJRCCM special section on interstitial lung disease #ILD
academic.oup.com/ajrccm/artic... @atscommunity.bsky.social
From mechanisms to clinical practice: introduction to an AJRCCM special section on interstitial lung disease
This issue's special section on interstitial lung disease (ILD) spans the translational spectrum of ILD research, encompassing clinical practice guidelines
academic.oup.com
October 1, 2026 at 7:00 PM
Reposted by Alexandre Serafim
criticalcarereviews.com
2026 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
September 30, 2026 at 9:27 PM
Reposted by Alexandre Serafim
stanfordneuro.bsky.social
Biological age vs chronological age—what the science says. Tony Wyss-Coray, PhD explains that biological age reflects the body’s aging trajectory and functional health—not just calendar years. https://med.stanford.edu/news/insights/2026/09/biological-chronological-age.html
Biological age versus chronological age: What the science says
Stanford Health Care delivers the highest levels of care and compassion. SHC treats cancer, heart disease, brain disorders, primary care issues, and many more.
med.stanford.edu
September 27, 2026 at 2:30 PM
Reposted by Alexandre Serafim
50501movement.bsky.social
Do you know your voting deadlines? Depending on your state, you may be running out of time to register to vote in the midterm elections. Take 10 minutes today to make sure you’re ready to vote by November 3 & vote early if you’re able. #HandsOffOurVote
September 27, 2026 at 12:43 PM
Reposted by Alexandre Serafim
annalsofem.bsky.social
Dexmedetomidine may offer a new option for selected adolescents with recurrent severe agitation during prolonged ED psychiatric boarding. This editorial asks the key questions: Is it necessary, feasible, safe, and ethical?

Paper 🔗 www.annemergmed.com/article/S019...
September 25, 2026 at 4:03 PM
Reposted by Alexandre Serafim
wfpiccs.bsky.social
🌏 Sharing ideas, advancing science & turning knowledge into practice that’s what brings Dr Vinay Nadkarni to #WFPICCS26 in Melbourne!

📍 Melbourne | 26–30 September 2026
👉 Explore the program 🔗 wfpiccs2026intensivecareasm.com/program/

#PedsICU
@openpediatrics.bsky.social @sapnakmd.bsky.social
September 23, 2026 at 12:58 PM
2210alex.bsky.social
#PedsICU
September 23, 2026 at 11:20 AM
Reposted by Alexandre Serafim
nejm.org
In a new NEJM Voices blog post, Don Dizon, MD, argues that artificial intelligence tools used in medicine will never replace clinicians. See why: https://nej.md/46BpP1a
This image is an illustration of two individuals sitting in a medical office. One is wearing a white coat with a stethoscope around his neck, and holding a tablet, representing a doctor, while the other is engaged in conversation. In the background, a computer monitor displays a document. The text reads: "NEJM Voices | Don Dizon, M.D. The Limits of AI in the Art of Medicine."
September 23, 2026 at 11:13 AM
Reposted by Alexandre Serafim
hswapnil.medsky.social
Following up on BEST FLUIDS - this RCT of ringers versus D5-NS post transplant with surrogate outcomes

www.kireports.org/article/S246... in @kireports.bsky.social

A bit more confidence that RL may be ~ plasmalyte?
Visual abstract
September 19, 2026 at 3:45 PM
Reposted by Alexandre Serafim
ryanmarino.bsky.social
Hotter, wetter summers, and milder winters - in addition to a lack of supportive infrastructure to prevent it - have helped dengue spread drastically around the globe in recent years, and into the continental United States. We do not have an approved vaccine for it and it’s difficult to test for.
Dengue-carrying mosquitoes expand their reach into new territories – including Florida
As dengue spreads further outside its normal tropical zones, doctors and patients need to know what to watch for.
theconversation.com
September 19, 2026 at 9:56 PM
Reposted by Alexandre Serafim
criticalcarereviews.com
The 2nd trial for CCR Frankfurt is CONFIDENCE

To be presented by Frederique Paulus & Siebe Blok

Can lung ultrasound-guided fluid removal increase ventilator-free days?

Join us 22–23 February, 2027

Registration opens shortly
criticalcarereviews.com/meetings/ccr... #CCRFrankfurt
Flyer for the CONFIDENCE trial, to be presented at CCR Frankfurt
September 19, 2026 at 3:45 PM
Reposted by Alexandre Serafim
wfpiccs.bsky.social
🌏 Explore the future of intensive care in vibrant #Melbourne at #WFPICCS26! 🎥 Prof @fenellagill.bsky.social shares what awaits

📍26–30 Sept 2026
👉 wfpiccs2026intensivecareasm.com/program/

🦘Stay longer to discover Melbourne & Victoria!
melbournecb.com.au/welcome-to-melbourne
#PedsICU #visitmelbourne
September 16, 2026 at 11:51 AM
Reposted by Alexandre Serafim
nejm.org
For patients with esophageal cancer, 5-year survival has improved in recent decades but rarely exceeds 20%. A new review summarizes risk factors, screening, and treatment for the two main histologic types. Read the full review: https://nej.md/3Tb2NuX
September 16, 2026 at 10:00 PM
Reposted by Alexandre Serafim
ryanmarino.bsky.social
All 4 deaths have been in the unvaccinated.
Pennsylvania reports fourth measles-related death, the most in US in decades | CNN
Pennsylvania has reported a fourth death related to measles, the latest in a growing outbreak that has also sparked ongoing political clashes.
www.cnn.com
September 15, 2026 at 8:12 PM
Reposted by Alexandre Serafim
criticalcarereviews.com
Clinical Management of Myocardial Infarction

CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
September 15, 2026 at 8:13 PM
Reposted by Alexandre Serafim
wfpiccs.bsky.social
🎥Our Immediate Past President, Brenda Morrow
previews her #WFPICCS26 talks on🌐research capacity & ethical challenges in resource-limited care

📍 Join us in Melbourne from Sep 26-30!
➡️Explore the program here 👉🔗https://wfpiccs2026intensivecareasm.com/program/
#PedsICU #globalhealth
September 14, 2026 at 11:46 AM
Reposted by Alexandre Serafim
papertis.bsky.social
Interesting to see a pragmatic trial design tackle a question that's been debated for years. The equipoise here seems genuine—speaks to how much we still don't know about fluid choice despite how fundamental it is to critical care.
medicine.stitches.today STITCHES Medicine - the Best of Medical Research @medicine.stitches.today · 24d
Balanced fluids do not improve kidney outcomes in septic shock over 0.9% saline; both treatments yield similar patient results.

by Balamuth F, Weiss SL (...) Kuppermann N et 59 al. in N Engl J Med #MedSky

👉 get more here

📖 read the article: https://www.nejm.org/doi/10.1056/NEJMoa2601969
September 12, 2026 at 5:37 PM
Reposted by Alexandre Serafim
bmjmedicine.bsky.social
New research from Padmini Selvaganesan and colleagues evaluates the effectiveness of SGLT2 inhibitors in reducing the risk of hospital admission for heart failure and mortality in patients with heart failure with preserved ejection fraction

https://bit.ly/4gQXE30
September 12, 2026 at 2:23 PM
Reposted by Alexandre Serafim
exceedhergrasp1.bsky.social
An article from @iwashyna.bsky.social about witnessing & reacting to misogynoir in an ED setting led me Prof. Koritha Mitchell's ( @profkori.bsky.social ) definition of know-your-place aggression and whewboy:

voices.nejm.org/doi/full/10....
I define know-your-place aggression as the flexible, dynamic array of forces that answer the achievements of marginalized groups such that their success brings aggression as often as praise. Any progress by those who are not straight, white, and male is answered by a backlash of violence—both literal and symbolic, both physical and discursive—that essentially says, know your place!
September 12, 2026 at 1:25 AM
Reposted by Alexandre Serafim
bmj.com
Nearly a third of the government’s nutrition advisors still have “significant” ties to the food industry including Coca Cola, Sainsbury’s, and Danone, reveals our new investigation.

Despite a new code of conduct banning links to the food industry, members with ties are allowed to remain in post
A third of UK government’s nutrition advisers are still paid by food industry, including Coca-Cola and Nestlé
Financial conflicts of interest remain rife in the Scientific Advisory Committee on Nutrition (SACN), BMJ analysis reveals. Despite a new code of conduct banning links to the food industry, members wi...
www.bmj.com
September 10, 2026 at 8:46 AM