Antibiotic Steward 🅱️C🆔🅿️🌟
@absteward.bsky.social
Stay up-to-date in Infectious Diseases, Clinical Pharmacist, Antibiotics, #IDTwitter t✨p influencer #interstellar #dune
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
Pinned
What’s in a Name? The Rise of Klebsiella pneumoniae: From Friedländer to Klebs
Within the family of Enterobacteriaceae, few species have evolved in parallel with
the history of clinical microbiology and infectious diseases as closely as Klebsiella
pneumoniae. First described in ...
www.cmi-comms.org
🔥Wow. Our article is published with the legend @bradspellberg.bsky.social 🎉🔥
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
🔥🔥Back online🔥🔥
IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky
www.idsociety.org/practice-gui...
IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky
www.idsociety.org/practice-gui...
September 9, 2026 at 4:12 PM
🔥🔥Back online🔥🔥
IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky
www.idsociety.org/practice-gui...
IDSA/ESCMID 2026 Guidelines on Staphylococcus aureus Bacteremia: Risk Stratification, Diagnostic Evaluation, and Management of Adults and Children Part-1 #idsky
www.idsociety.org/practice-gui...
🔥Just published 🔥
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association #idsky
www.ahajournals.org/doi/10.1161/...
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association #idsky
www.ahajournals.org/doi/10.1161/...
September 8, 2026 at 4:40 PM
🔥Just published 🔥
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association #idsky
www.ahajournals.org/doi/10.1161/...
Infective Endocarditis: Diagnosis, Antibiotic Therapy, and Management: A Scientific Statement From the American Heart Association #idsky
www.ahajournals.org/doi/10.1161/...
🔥Wow. Our article is published with the legend @bradspellberg.bsky.social 🎉🔥
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
What’s in a Name? The Rise of Klebsiella pneumoniae: From Friedländer to Klebs
Within the family of Enterobacteriaceae, few species have evolved in parallel with
the history of clinical microbiology and infectious diseases as closely as Klebsiella
pneumoniae. First described in ...
www.cmi-comms.org
August 13, 2026 at 2:14 PM
🔥Wow. Our article is published with the legend @bradspellberg.bsky.social 🎉🔥
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
A journey that started with a simple question: What’s in a name?
Today, I’m incredibly grateful to see our article published in @cmicomms.bsky.social
EnJoy! #idsky
www.cmi-comms.org/article/S295...
What's in a name?
The story of Coccidioides begins with a medical trainee, a mistaken identity, and a discovery that changed medical mycology.
More than a century later, that trainee would have a species named in his honor.
And yes—there's a reason it's called "Valley fever." #IDsky
The story of Coccidioides begins with a medical trainee, a mistaken identity, and a discovery that changed medical mycology.
More than a century later, that trainee would have a species named in his honor.
And yes—there's a reason it's called "Valley fever." #IDsky
August 5, 2026 at 8:18 PM
What's in a name?
The story of Coccidioides begins with a medical trainee, a mistaken identity, and a discovery that changed medical mycology.
More than a century later, that trainee would have a species named in his honor.
And yes—there's a reason it's called "Valley fever." #IDsky
The story of Coccidioides begins with a medical trainee, a mistaken identity, and a discovery that changed medical mycology.
More than a century later, that trainee would have a species named in his honor.
And yes—there's a reason it's called "Valley fever." #IDsky
🔥🔥IDSA AMR Guidance 2026🔥🔥
🔺Notable Updates from the 2024 IDSA AMR Guidance Document
🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky
www.idsociety.org/practice-gui...
🔺Notable Updates from the 2024 IDSA AMR Guidance Document
🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky
www.idsociety.org/practice-gui...
July 30, 2026 at 10:32 PM
🔥🔥IDSA AMR Guidance 2026🔥🔥
🔺Notable Updates from the 2024 IDSA AMR Guidance Document
🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky
www.idsociety.org/practice-gui...
🔺Notable Updates from the 2024 IDSA AMR Guidance Document
🔺Meropenem dosing update: individualized dosing approach (1–2 g IV q8h) with higher doses considered in selected clinical scenarios. #idsky
www.idsociety.org/practice-gui...
🔥 Update 🔥
The IDSA AMR Guidance 2026 link is now back online.
You can access the guidance through the original link below.
I'll be sharing the Notable Updates from the 2024 IDSA AMR Guidance Document soon. #idsky
The IDSA AMR Guidance 2026 link is now back online.
You can access the guidance through the original link below.
I'll be sharing the Notable Updates from the 2024 IDSA AMR Guidance Document soon. #idsky
🔥🔥Just published 🔥🔥
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
July 30, 2026 at 9:53 PM
🔥 Update 🔥
The IDSA AMR Guidance 2026 link is now back online.
You can access the guidance through the original link below.
I'll be sharing the Notable Updates from the 2024 IDSA AMR Guidance Document soon. #idsky
The IDSA AMR Guidance 2026 link is now back online.
You can access the guidance through the original link below.
I'll be sharing the Notable Updates from the 2024 IDSA AMR Guidance Document soon. #idsky
🆕🔥🔴ISLEND-1 RCT
Among persons with virologically suppressed HIV-1, once-weekly oral Islatravir–Lenacapavir was noninferior to once-daily oral bictegravir emtricitabine tenofovir alafenamide B/F/TAF in maintaining HIV viral load suppression #IDsky #hivsky
www.nejm.org/doi/full/10....
Among persons with virologically suppressed HIV-1, once-weekly oral Islatravir–Lenacapavir was noninferior to once-daily oral bictegravir emtricitabine tenofovir alafenamide B/F/TAF in maintaining HIV viral load suppression #IDsky #hivsky
www.nejm.org/doi/full/10....
Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment | NEJM
Once-daily, single-tablet regimens have transformed care for persons living with human immunodeficiency virus type 1 (HIV-1); however, challenges to adherence continue to limit effective treatment....
www.nejm.org
July 29, 2026 at 9:08 PM
🆕🔥🔴ISLEND-1 RCT
Among persons with virologically suppressed HIV-1, once-weekly oral Islatravir–Lenacapavir was noninferior to once-daily oral bictegravir emtricitabine tenofovir alafenamide B/F/TAF in maintaining HIV viral load suppression #IDsky #hivsky
www.nejm.org/doi/full/10....
Among persons with virologically suppressed HIV-1, once-weekly oral Islatravir–Lenacapavir was noninferior to once-daily oral bictegravir emtricitabine tenofovir alafenamide B/F/TAF in maintaining HIV viral load suppression #IDsky #hivsky
www.nejm.org/doi/full/10....
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Yikes.
Never have I treated something that probably doesn't need to be treated so aggressively. Or at least expensively.
Never have I treated something that probably doesn't need to be treated so aggressively. Or at least expensively.
July 29, 2026 at 1:46 AM
Yikes.
Never have I treated something that probably doesn't need to be treated so aggressively. Or at least expensively.
Never have I treated something that probably doesn't need to be treated so aggressively. Or at least expensively.
Update: The original link appears to be temporarily unavailable. I'll share the updated official link once it's available. #idsky
🔥🔥Just published 🔥🔥
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
July 28, 2026 at 2:44 PM
Update: The original link appears to be temporarily unavailable. I'll share the updated official link once it's available. #idsky
🔥🔥Just published 🔥🔥
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
July 27, 2026 at 4:06 PM
🔥🔥Just published 🔥🔥
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
IDSA AMR Guidance 2026
IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
🔺ESBL , AmpC Enterobacterales
🔺CRE
🔺DTR P. aeruginosa
🔺CRAB
🔺Stenotrophomonas maltophilia #idsky
www.idsociety.org/practice-gui...
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Love seeing this data. Skip phenomenon is rare and usually occurs in the context of a clinical change. No need to repeat BCx again when already cleared....and we might be able to get away with a single set to detect clearance of SAB
Staphylococcus aureus bacteremia guidelines recommend obtaining FUBCs every 2-4 days until bacteremia clearance!
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
Routine serial follow-up blood cultures after a negative result within 48 hours of methicillin-susceptible Staphylococcus aureus bacteremia: low yield, high cost
Early skip phenomenon in Staphylococcus aureus bacteremia is rare (3.1%) with a very low risk of missed persistent bacteremia (1%). A practical day-2 focus
academic.oup.com
July 16, 2026 at 3:26 AM
Love seeing this data. Skip phenomenon is rare and usually occurs in the context of a clinical change. No need to repeat BCx again when already cleared....and we might be able to get away with a single set to detect clearance of SAB
A thoughtful editorial
Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? #idsky
academic.oup.com/cid/article-...
Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? #idsky
academic.oup.com/cid/article-...
July 15, 2026 at 6:13 PM
A thoughtful editorial
Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? #idsky
academic.oup.com/cid/article-...
Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? #idsky
academic.oup.com/cid/article-...
Staphylococcus aureus bacteremia guidelines recommend obtaining FUBCs every 2-4 days until bacteremia clearance!
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
Routine serial follow-up blood cultures after a negative result within 48 hours of methicillin-susceptible Staphylococcus aureus bacteremia: low yield, high cost
Early skip phenomenon in Staphylococcus aureus bacteremia is rare (3.1%) with a very low risk of missed persistent bacteremia (1%). A practical day-2 focus
academic.oup.com
July 15, 2026 at 3:10 PM
Staphylococcus aureus bacteremia guidelines recommend obtaining FUBCs every 2-4 days until bacteremia clearance!
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
🆕💥💥🟢 cohort study: Routine serial follow-up blood cultures after a negative result within 48 hours of MSSA bacteremia: low yield, high cost #idsky
academic.oup.com/cid/article/...
🆕💥🟢Among 305 episodes with suspected infective endocarditis and valve strands the majority did not represent IE.
Recurrence of IE due to the same microorganism within one year was significantly more frequent among episodes with IE compared to those without #idsky
academic.oup.com/cid/article/...
Recurrence of IE due to the same microorganism within one year was significantly more frequent among episodes with IE compared to those without #idsky
academic.oup.com/cid/article/...
Validate User
academic.oup.com
June 20, 2026 at 2:50 PM
🆕💥🟢Among 305 episodes with suspected infective endocarditis and valve strands the majority did not represent IE.
Recurrence of IE due to the same microorganism within one year was significantly more frequent among episodes with IE compared to those without #idsky
academic.oup.com/cid/article/...
Recurrence of IE due to the same microorganism within one year was significantly more frequent among episodes with IE compared to those without #idsky
academic.oup.com/cid/article/...
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Aw🫰SNAP🫰
Cefazolin vs anti-staphylococcal PCN
⬇️⬇️⬇️
Cefazolin vs anti-staphylococcal PCN
⬇️⬇️⬇️
🔥Just published 🔥NEJM
SNAP RCT
In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky
www.nejm.org/doi/full/10....
SNAP RCT
In patients with MSSA bacteremia, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality and was associated with a lower incidence of acute kidney injury. #idsky
www.nejm.org/doi/full/10....
Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia | NEJM
Staphylococcus aureus bacteremia is associated with high mortality. Whether cefazolin or an antistaphylococcal penicillin should be preferred for the treatment of methicillin-susceptible S. aureus ...
www.nejm.org
June 20, 2026 at 2:00 PM
Aw🫰SNAP🫰
Cefazolin vs anti-staphylococcal PCN
⬇️⬇️⬇️
Cefazolin vs anti-staphylococcal PCN
⬇️⬇️⬇️
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
If there were PK/PD issues with fosfo, the problem might arise not on early TOC, but on relapses of non-cystitis UTI.
In this subanalysis of patients switched to oral in FOREST trial, more relapses were observed with fosfo for bacteremic E. coli UTI.
academic.oup.com/jac/article/... #IDSky #UTIsky
In this subanalysis of patients switched to oral in FOREST trial, more relapses were observed with fosfo for bacteremic E. coli UTI.
academic.oup.com/jac/article/... #IDSky #UTIsky
June 20, 2026 at 8:02 AM
If there were PK/PD issues with fosfo, the problem might arise not on early TOC, but on relapses of non-cystitis UTI.
In this subanalysis of patients switched to oral in FOREST trial, more relapses were observed with fosfo for bacteremic E. coli UTI.
academic.oup.com/jac/article/... #IDSky #UTIsky
In this subanalysis of patients switched to oral in FOREST trial, more relapses were observed with fosfo for bacteremic E. coli UTI.
academic.oup.com/jac/article/... #IDSky #UTIsky
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Caveats:
- FOREST was 100% bacteremic UTI
- A lower dose of oral fosfo was used (3g/48h).
- Definition of relapse was more strict, requiring a new isolation of E. coli with same phenotype.
- Absolute risk difference still low (11%), so definitely an option to consider if no other options!
#IDSky
- FOREST was 100% bacteremic UTI
- A lower dose of oral fosfo was used (3g/48h).
- Definition of relapse was more strict, requiring a new isolation of E. coli with same phenotype.
- Absolute risk difference still low (11%), so definitely an option to consider if no other options!
#IDSky
June 20, 2026 at 8:14 AM
Caveats:
- FOREST was 100% bacteremic UTI
- A lower dose of oral fosfo was used (3g/48h).
- Definition of relapse was more strict, requiring a new isolation of E. coli with same phenotype.
- Absolute risk difference still low (11%), so definitely an option to consider if no other options!
#IDSky
- FOREST was 100% bacteremic UTI
- A lower dose of oral fosfo was used (3g/48h).
- Definition of relapse was more strict, requiring a new isolation of E. coli with same phenotype.
- Absolute risk difference still low (11%), so definitely an option to consider if no other options!
#IDSky
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Observational indeed
June 20, 2026 at 3:50 AM
Observational indeed
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Retrospective study. 😊
June 19, 2026 at 8:03 PM
Retrospective study. 😊
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
Reposted by Antibiotic Steward 🅱️C🆔🅿️🌟
