Alexa Sadier
@aigverte.bsky.social
CNRS PI at Institut des Sciences de l'Evolution de Montpellier | Evo-devo - Bats - Teeth - Dev Constraints - Adaptation | Evolution on Earth and beyond | ERC NOVELTEETH |
Co-host @podcastscience | Cham steepskier
website: alexasadier.com
Co-host @podcastscience | Cham steepskier
website: alexasadier.com
Pinned
INÉDIT 🎬 Comment les chauves-souris ont-elles donné naissance à une telle diversité ? 🦇
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
C'est sorti ! Un reportage des équipes du CNRS sur nos recherches et l'importance d'étudier la diversité des chauves-souris et leur evolution. Une occasion aussi de découvrir la splendeur de Trinidad et nos collaborateurs grâce aux images de notre film Spectral
@erc.europa.eu @isemevol.bsky.social
@erc.europa.eu @isemevol.bsky.social
Reposted by Alexa Sadier
MERFISHEYES: Web-based Visualization and Sharing Platform for Single-cell and Single-molecule Spatial Transcriptomics https://www.biorxiv.org/content/10.64898/2026.09.20.753029v1
September 25, 2026 at 4:46 PM
MERFISHEYES: Web-based Visualization and Sharing Platform for Single-cell and Single-molecule Spatial Transcriptomics https://www.biorxiv.org/content/10.64898/2026.09.20.753029v1
C'est sorti ! Un reportage des équipes du CNRS sur nos recherches et l'importance d'étudier la diversité des chauves-souris et leur evolution. Une occasion aussi de découvrir la splendeur de Trinidad et nos collaborateurs grâce aux images de notre film Spectral
@erc.europa.eu @isemevol.bsky.social
@erc.europa.eu @isemevol.bsky.social
INÉDIT 🎬 Comment les chauves-souris ont-elles donné naissance à une telle diversité ? 🦇
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
September 25, 2026 at 4:30 PM
C'est sorti ! Un reportage des équipes du CNRS sur nos recherches et l'importance d'étudier la diversité des chauves-souris et leur evolution. Une occasion aussi de découvrir la splendeur de Trinidad et nos collaborateurs grâce aux images de notre film Spectral
@erc.europa.eu @isemevol.bsky.social
@erc.europa.eu @isemevol.bsky.social
Reposted by Alexa Sadier
INÉDIT 🎬 Comment les chauves-souris ont-elles donné naissance à une telle diversité ? 🦇
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
September 25, 2026 at 2:22 PM
INÉDIT 🎬 Comment les chauves-souris ont-elles donné naissance à une telle diversité ? 🦇
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
Avec plus de 1500 espèces, leur évolution est fascinante.
Pour le savoir, direction les grottes et les forêts de Trinité-et-Tobago. 🌴
Le reportage complet 👉 lejournal.cnrs.fr/videos/les-c...
Reposted by Alexa Sadier
If you're an ECR or postdoc in need of funding to travel for an experiment or to learn a new technique, make sure you apply for a JEB Travelling Fellowship
www.biologists.com/grants/trave...
#PostdocAppreciationWeek #NPAW #PostdocAppreciation
Find out more at doi.org/10.1242/jeb....
www.biologists.com/grants/trave...
#PostdocAppreciationWeek #NPAW #PostdocAppreciation
Find out more at doi.org/10.1242/jeb....
September 25, 2026 at 10:00 AM
If you're an ECR or postdoc in need of funding to travel for an experiment or to learn a new technique, make sure you apply for a JEB Travelling Fellowship
www.biologists.com/grants/trave...
#PostdocAppreciationWeek #NPAW #PostdocAppreciation
Find out more at doi.org/10.1242/jeb....
www.biologists.com/grants/trave...
#PostdocAppreciationWeek #NPAW #PostdocAppreciation
Find out more at doi.org/10.1242/jeb....
Reposted by Alexa Sadier
This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪
Had a UKRI funded grant proposal rejected at the "AI triage stage". "This AI-based triage was used only to identify approximately 50% of the strongest proposals to take forward to full human review." 🧪 #academicsky
September 25, 2026 at 6:56 AM
This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪
Reposted by Alexa Sadier
🦇 Bat1K's biggest paper yet is out. Largest bat genome + fossil study ever: 103 genomes, 44 fossils, 137 researchers. We rewrote the bat family tree! Bats likely originated in Europe ~65 million years ago, not Asia, Africa or Americas. @bat1kgenomes.bsky.social
doi.org/10.1038/s41586-026-11007-3
doi.org/10.1038/s41586-026-11007-3
September 23, 2026 at 3:12 PM
🦇 Bat1K's biggest paper yet is out. Largest bat genome + fossil study ever: 103 genomes, 44 fossils, 137 researchers. We rewrote the bat family tree! Bats likely originated in Europe ~65 million years ago, not Asia, Africa or Americas. @bat1kgenomes.bsky.social
doi.org/10.1038/s41586-026-11007-3
doi.org/10.1038/s41586-026-11007-3
Reposted by Alexa Sadier
Where did bats come from?🦇🌍
After decades of debate, the biggest bat genome + fossil study ever done has an answer - and it’s not where anyone expected!
🤩OUR PHASE 1 FLAGSHIP is out today in nature! doi.org/10.1038/s415...
A thread 🧵
After decades of debate, the biggest bat genome + fossil study ever done has an answer - and it’s not where anyone expected!
🤩OUR PHASE 1 FLAGSHIP is out today in nature! doi.org/10.1038/s415...
A thread 🧵
Reference genomes and fossils revise bat family phylogeny and biogeography - Nature
An updated phylogeny of bats is presented, based on new genome assemblies and many ancient fossils and including all known bat families.
doi.org
September 23, 2026 at 3:52 PM
Where did bats come from?🦇🌍
After decades of debate, the biggest bat genome + fossil study ever done has an answer - and it’s not where anyone expected!
🤩OUR PHASE 1 FLAGSHIP is out today in nature! doi.org/10.1038/s415...
A thread 🧵
After decades of debate, the biggest bat genome + fossil study ever done has an answer - and it’s not where anyone expected!
🤩OUR PHASE 1 FLAGSHIP is out today in nature! doi.org/10.1038/s415...
A thread 🧵
Reposted by Alexa Sadier
Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach
briscoelab.org/blog-quantif...
briscoelab.org/blog-quantif...
Quantifying Waddington's Landscape | Briscoe Lab
I have written before about how two conceptual frameworks have shaped our thinking about cell fate, Waddington's epigenetic landscape and Davidson's gene...
briscoelab.org
September 22, 2026 at 11:12 AM
Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach
briscoelab.org/blog-quantif...
briscoelab.org/blog-quantif...
Reposted by Alexa Sadier
"Philosophy of Biology: The power of theory in the life sciences"
elifesciences.org/articles/112...
@zdblount.bsky.social shared this thought-provoking paper with the lab group.
elifesciences.org/articles/112...
@zdblount.bsky.social shared this thought-provoking paper with the lab group.
Philosophy of Biology: The power of theory in the life sciences
Theory can help address cell and molecular biology’s major challenges, particularly those arising from large omics datasets.
elifesciences.org
September 22, 2026 at 5:29 PM
"Philosophy of Biology: The power of theory in the life sciences"
elifesciences.org/articles/112...
@zdblount.bsky.social shared this thought-provoking paper with the lab group.
elifesciences.org/articles/112...
@zdblount.bsky.social shared this thought-provoking paper with the lab group.
Reposted by Alexa Sadier
Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S...
@helsinki-biotech.bsky.social @helsinki.fi
@helsinki-biotech.bsky.social @helsinki.fi
September 22, 2026 at 8:10 AM
Our collaborative paper on snake coiling is now out in the latest issue of @currentbiology.bsky.social and featured on the cover! 🎉 Delighted to see our work highlighted this way. You can read it here: authors.elsevier.com/c/1ni9h3QW8S...
@helsinki-biotech.bsky.social @helsinki.fi
@helsinki-biotech.bsky.social @helsinki.fi
Reposted by Alexa Sadier
Excited that our new paper with @henrylabsymbio.bsky.social and Kerry Oliver is out @pnas.org! We show that mobile genetic elements can spread adaptive host-benefiting traits across heritable insect symbionts on eco-evolutionary timescales.🧵
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Phenotypic divergence is driven by mobile genetic elements in a heritable insect symbiont | PNAS
Heritable microbes profoundly influence insect biology, yet the traits they confer
often evolve rapidly and differ among closely related symbiont s...
www.pnas.org
September 21, 2026 at 8:13 PM
Excited that our new paper with @henrylabsymbio.bsky.social and Kerry Oliver is out @pnas.org! We show that mobile genetic elements can spread adaptive host-benefiting traits across heritable insect symbionts on eco-evolutionary timescales.🧵
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Alexa Sadier
🚨We're hiring a new Curator of Mammals!!🚨
🦍🐕🦝🐅🦓🦌🐃🐖🐏🐫🐘🦏🦛🐿️🦔🦇🦥🦦🦨🦘🦡🐋🦭🦒🧸
Come join the Vertebrate Unit at @nhmdk.bsky.social—a fantastic team in the heart of Denmark's beautiful capital! Amazing collections, incredible history.
Please share widely! 🧪🏛️
candidate.hr-manager.net/ApplicationI...
🦍🐕🦝🐅🦓🦌🐃🐖🐏🐫🐘🦏🦛🐿️🦔🦇🦥🦦🦨🦘🦡🐋🦭🦒🧸
Come join the Vertebrate Unit at @nhmdk.bsky.social—a fantastic team in the heart of Denmark's beautiful capital! Amazing collections, incredible history.
Please share widely! 🧪🏛️
candidate.hr-manager.net/ApplicationI...
Tenure Track Assistant Professor or Associate Professor and Curator of Mammals
Tenure Track Assistant Professor / Associate Professor, and Curator of Mammals at Natural History Museum Denmark The Natural History Museum Denmark wishes to ap
candidate.hr-manager.net
September 21, 2026 at 9:13 PM
🚨We're hiring a new Curator of Mammals!!🚨
🦍🐕🦝🐅🦓🦌🐃🐖🐏🐫🐘🦏🦛🐿️🦔🦇🦥🦦🦨🦘🦡🐋🦭🦒🧸
Come join the Vertebrate Unit at @nhmdk.bsky.social—a fantastic team in the heart of Denmark's beautiful capital! Amazing collections, incredible history.
Please share widely! 🧪🏛️
candidate.hr-manager.net/ApplicationI...
🦍🐕🦝🐅🦓🦌🐃🐖🐏🐫🐘🦏🦛🐿️🦔🦇🦥🦦🦨🦘🦡🐋🦭🦒🧸
Come join the Vertebrate Unit at @nhmdk.bsky.social—a fantastic team in the heart of Denmark's beautiful capital! Amazing collections, incredible history.
Please share widely! 🧪🏛️
candidate.hr-manager.net/ApplicationI...
Reposted by Alexa Sadier
NEW PREPRINT!
An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
September 21, 2026 at 4:15 PM
NEW PREPRINT!
An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
An evo-devo look at how new cerebellar nuclei are made. Spoiler: it’s all driven by region-specific excitatory progenitors in the early rhombic lip; inhibitory neurons fill in later. If you care about brain evolution or cerebellar development, check it out: tinyurl.com/CNdevelopment
Reposted by Alexa Sadier
There is still time to apply for the EMBL International PhD Programme! 📢
Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research.
Research groups across EMBL are recruiting now! bit.ly/4x9Edss
Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research.
Research groups across EMBL are recruiting now! bit.ly/4x9Edss
September 21, 2026 at 9:42 AM
There is still time to apply for the EMBL International PhD Programme! 📢
Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research.
Research groups across EMBL are recruiting now! bit.ly/4x9Edss
Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research.
Research groups across EMBL are recruiting now! bit.ly/4x9Edss
Reposted by Alexa Sadier
Must admit, ever since I was a kid, I’ve dreamt of seeing microscopy images of #protists in @lemonde.fr
Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹
One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹
One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
September 21, 2026 at 5:40 PM
Must admit, ever since I was a kid, I’ve dreamt of seeing microscopy images of #protists in @lemonde.fr
Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹
One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
Today, protists are everywhere, and several images were taken by the team. And seeing #ichthyosporeans there too?! 🥹
One step closer to showcasing the beauty of the invisible microbial world. 🔬✨
Reposted by Alexa Sadier
21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk!
marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
MSCA Postdoctoral Fellowships 2026 receives record number of applications
The 2026 call has attracted considerable interest from the research community with 21,627 applications submitted.
marie-sklodowska-curie-actions.ec.europa.eu
September 20, 2026 at 12:16 PM
21627 applications. Nothing to celebrate here. Impossible to evaluate fairly & safely. Neither the science (too diverse & possibly LLM generated) nor the soft criteria (likely LLM generated). Without an interview stage - a security risk!
marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
marie-sklodowska-curie-actions.ec.europa.eu/whats-new/ne...
Reposted by Alexa Sadier
Mechanisms of Phenotypic Evolution from Molecules to Organisms: Integrating Evolutionary Biochemistry and Evolutionary Developmental Biology https://pubmed.ncbi.nlm.nih.gov/42751651/ #EvoDevo
September 19, 2026 at 1:00 PM
Mechanisms of Phenotypic Evolution from Molecules to Organisms: Integrating Evolutionary Biochemistry and Evolutionary Developmental Biology https://pubmed.ncbi.nlm.nih.gov/42751651/ #EvoDevo
Reposted by Alexa Sadier
Are you a senior scientist looking to expand your scientific horizons through a sabbatical? 🔬
Then the EMBL Sabbatical Programme is a great opportunity for you!
You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months.
🔗Apply here: bit.ly/sabbatical26
Then the EMBL Sabbatical Programme is a great opportunity for you!
You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months.
🔗Apply here: bit.ly/sabbatical26
September 17, 2026 at 7:13 AM
Are you a senior scientist looking to expand your scientific horizons through a sabbatical? 🔬
Then the EMBL Sabbatical Programme is a great opportunity for you!
You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months.
🔗Apply here: bit.ly/sabbatical26
Then the EMBL Sabbatical Programme is a great opportunity for you!
You could receive up to €15,000 and be based at any of EMBL’s six sites for 3 to 6 months.
🔗Apply here: bit.ly/sabbatical26
Reposted by Alexa Sadier
🔬🧪 We're hiring postdocs&engineers at Institut de la Vision in AMAZING Paris 🇫🇷!!
Join a dynamic team working at the nexus of retina developmental biology, spatial omics & advanced imaging
Ambitious science in a supportive & young inclusive team 🚀
DM me for more info & please share 🙏 #academicsky
Join a dynamic team working at the nexus of retina developmental biology, spatial omics & advanced imaging
Ambitious science in a supportive & young inclusive team 🚀
DM me for more info & please share 🙏 #academicsky
September 15, 2026 at 9:00 PM
🔬🧪 We're hiring postdocs&engineers at Institut de la Vision in AMAZING Paris 🇫🇷!!
Join a dynamic team working at the nexus of retina developmental biology, spatial omics & advanced imaging
Ambitious science in a supportive & young inclusive team 🚀
DM me for more info & please share 🙏 #academicsky
Join a dynamic team working at the nexus of retina developmental biology, spatial omics & advanced imaging
Ambitious science in a supportive & young inclusive team 🚀
DM me for more info & please share 🙏 #academicsky
Reposted by Alexa Sadier
1/6 An extraordinary @nature.com paper has just landed from the lab of @sergiuppasca.bsky.social. They found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells.
September 16, 2026 at 5:29 PM
1/6 An extraordinary @nature.com paper has just landed from the lab of @sergiuppasca.bsky.social. They found a way to create "xenocortical mice" which have ~92% of their cortex occupied by a cortical organoid derived from human stem cells.
Reposted by Alexa Sadier
C'est officiel ! 🥳 #Podcast #Science revient en public ! Vous pouvez réservez votre entrée gratuite pour les DEUX prochaines Radio Dessinées du 3 et 4 octobre par ici : www.podcastscience.fm/3-4-octobre-...
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
August 31, 2026 at 3:37 PM
C'est officiel ! 🥳 #Podcast #Science revient en public ! Vous pouvez réservez votre entrée gratuite pour les DEUX prochaines Radio Dessinées du 3 et 4 octobre par ici : www.podcastscience.fm/3-4-octobre-...
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
Reposted by Alexa Sadier
À NE PAS LOUPER !!!!
Pour vous inscrire :
--> Écoute moi un mouton (Samedi 3/10 13h) my.weezevent.com/radio-dessin...
--> Le Palais a du goût (Dimanche 4/10 14h30) my.weezevent.com/radio-dessin...
Pour vous inscrire :
--> Écoute moi un mouton (Samedi 3/10 13h) my.weezevent.com/radio-dessin...
--> Le Palais a du goût (Dimanche 4/10 14h30) my.weezevent.com/radio-dessin...
C'est officiel ! 🥳 #Podcast #Science revient en public ! Vous pouvez réservez votre entrée gratuite pour les DEUX prochaines Radio Dessinées du 3 et 4 octobre par ici : www.podcastscience.fm/3-4-octobre-...
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
Des événements organisés par Claire 🥰
Des affiches réalisées par @xapuyo.bsky.social 😻
September 14, 2026 at 3:23 PM
À NE PAS LOUPER !!!!
Pour vous inscrire :
--> Écoute moi un mouton (Samedi 3/10 13h) my.weezevent.com/radio-dessin...
--> Le Palais a du goût (Dimanche 4/10 14h30) my.weezevent.com/radio-dessin...
Pour vous inscrire :
--> Écoute moi un mouton (Samedi 3/10 13h) my.weezevent.com/radio-dessin...
--> Le Palais a du goût (Dimanche 4/10 14h30) my.weezevent.com/radio-dessin...
Reposted by Alexa Sadier
Excited to share our first evo-devo modeling study exploring the developmental origins of the evolutionary transition from dentine–enameloid to dentine–enamel in vertebrates! 🦷
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
August 5, 2026 at 11:31 AM
Excited to share our first evo-devo modeling study exploring the developmental origins of the evolutionary transition from dentine–enameloid to dentine–enamel in vertebrates! 🦷
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Alexa Sadier
Beautiful new publication by my dear friends João F. Botelho and Macarena Faunes, about development of interdigital membranes in ducks
royalsocietypublishing.org/rsos/article...
royalsocietypublishing.org/rsos/article...
September 9, 2026 at 3:05 PM
Beautiful new publication by my dear friends João F. Botelho and Macarena Faunes, about development of interdigital membranes in ducks
royalsocietypublishing.org/rsos/article...
royalsocietypublishing.org/rsos/article...
Reposted by Alexa Sadier
Ambergris, a rare waxy substance produced by sperm #whales, is highly valued for its fragrance but can be difficult to authenticate when found washed ashore. This #RSOS study combined DNA metabarcoding with chemical profiling to improve identification of ambergris specimens: doi.org/10.1098/rsos...
September 9, 2026 at 7:00 AM
Ambergris, a rare waxy substance produced by sperm #whales, is highly valued for its fragrance but can be difficult to authenticate when found washed ashore. This #RSOS study combined DNA metabarcoding with chemical profiling to improve identification of ambergris specimens: doi.org/10.1098/rsos...