Antoine Taly
@ataly.bsky.social
Researcher at CNRS interested in the biophysics of proteins. Modelling membrane proteins and their interaction with ligands. Working in Paris.
Reposted by Antoine Taly
BREAKING NEWS
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
October 5, 2026 at 9:40 AM
BREAKING NEWS
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Reposted by Antoine Taly
Happy to share our Application Note on RNA and chemical probing.
MARS-RNA: An Automated Pipeline for Correlating RNA
Molecular Dynamics Trajectories with Chemical Probing Data pubs.acs.org/jcisd8/artic...
MARS-RNA: An Automated Pipeline for Correlating RNA
Molecular Dynamics Trajectories with Chemical Probing Data pubs.acs.org/jcisd8/artic...
MARS-RNA: An Automated Pipeline for Correlating RNA
Molecular Dynamics Trajectories with Chemical Probing Data
Abstract. Ribonucleic acid
(RNA) molecules fold into complex, highly dynamic
three-dimensional conformational structures that govern their biological
activ
pubs.acs.org
September 25, 2026 at 11:20 AM
Happy to share our Application Note on RNA and chemical probing.
MARS-RNA: An Automated Pipeline for Correlating RNA
Molecular Dynamics Trajectories with Chemical Probing Data pubs.acs.org/jcisd8/artic...
MARS-RNA: An Automated Pipeline for Correlating RNA
Molecular Dynamics Trajectories with Chemical Probing Data pubs.acs.org/jcisd8/artic...
Reposted by Antoine Taly
We’re looking for a new colleague in Würzburg!
🌱 W3 Professorship in Plant Metabolism
💊 Chair of Pharmaceutical Biology
🧪 Head of the Metabolomics Core Unit
jobs.zeit.de/jobs/univers...
Please spread the word! Questions? Feel free to contact me.
www.biologie.uni-wuerzburg.de/en/about-the...
🌱 W3 Professorship in Plant Metabolism
💊 Chair of Pharmaceutical Biology
🧪 Head of the Metabolomics Core Unit
jobs.zeit.de/jobs/univers...
Please spread the word! Questions? Feel free to contact me.
www.biologie.uni-wuerzburg.de/en/about-the...
W3_Pflanzenmetabolismus - FACULTY OF BIOLOGY
www.biologie.uni-wuerzburg.de
September 24, 2026 at 11:10 AM
We’re looking for a new colleague in Würzburg!
🌱 W3 Professorship in Plant Metabolism
💊 Chair of Pharmaceutical Biology
🧪 Head of the Metabolomics Core Unit
jobs.zeit.de/jobs/univers...
Please spread the word! Questions? Feel free to contact me.
www.biologie.uni-wuerzburg.de/en/about-the...
🌱 W3 Professorship in Plant Metabolism
💊 Chair of Pharmaceutical Biology
🧪 Head of the Metabolomics Core Unit
jobs.zeit.de/jobs/univers...
Please spread the word! Questions? Feel free to contact me.
www.biologie.uni-wuerzburg.de/en/about-the...
Reposted by Antoine Taly
In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫
Here all the info
ibecbarcelona.eu/predoctoral-...
Here all the info
ibecbarcelona.eu/predoctoral-...
ibecbarcelona.eu
September 22, 2026 at 7:18 AM
In @pcusachs.bsky.social’s lab at @ibecbarcelona.eu we have a fully founded open PhD position! It’s a very nice working environment & can promise cool mechanobiology🔬🧫
Here all the info
ibecbarcelona.eu/predoctoral-...
Here all the info
ibecbarcelona.eu/predoctoral-...
Reposted by Antoine Taly
The PhD and Postdoc application links are now live! Come join me at UNIL to work on deep learning for protein structure, interactions & design. pickybinders.org#open-positions
September 16, 2026 at 12:21 PM
The PhD and Postdoc application links are now live! Come join me at UNIL to work on deep learning for protein structure, interactions & design. pickybinders.org#open-positions
Reposted by Antoine Taly
Yep, 100% this ⬇️
(and my lab is eligible for such positions 😜)
(and my lab is eligible for such positions 😜)
This is your yearly reminder that if you're interested in applying to a CNRS researcher permanent position in France, NOW is the right time to contact labs and build a research project.
(not in December when the applications will officially open)
(not in December when the applications will officially open)
ALF It's time
Alt: ALF It's time
static.klipy.com
September 8, 2026 at 12:44 PM
Yep, 100% this ⬇️
(and my lab is eligible for such positions 😜)
(and my lab is eligible for such positions 😜)
Reposted by Antoine Taly
If you read closely, it is clear that @chess.com indeed was referring to the game tree complexity, and not the positions, since they say "possible chess games". I assume M*sk used and LLM to, which ofc is unable to get pragmatics.
Possibly @chess.com meant to refer to game tree complexity (~10^120) not just # legal positions (~10^44), compared to the number of estimated atoms in universe (~10^80). Btw, even though ~10^44 << ~10^80 it's mindbogglingly large. Cf. number of seconds that passed since the Big Bang: ~10^27. 💥🧵
lol
September 5, 2026 at 6:01 PM
If you read closely, it is clear that @chess.com indeed was referring to the game tree complexity, and not the positions, since they say "possible chess games". I assume M*sk used and LLM to, which ofc is unable to get pragmatics.
Reposted by Antoine Taly
If you want clear-headed and accessible reporting on AI incidents, this example is a gold standard.
Bless the hearts of people like @eryk.bsky.social but I'm learning that no amount of reasonable voice makes a difference when you have bought out media, academics and politicians + trillion dollar companies pushing Cookie Monster theory 🙄
mail.cyberneticforests.com/models-dont-...
mail.cyberneticforests.com/models-dont-...
Models Don't Go Rogue
Stochastic Flocks & Cybersecurity 'Pandemonium'
💡This essay was drafted from my appearance on Mél Hogan's podcast, The Data Fix, discussing the OpenAI / Hugging Face hack. Embedded below or find it o...
mail.cyberneticforests.com
September 3, 2026 at 10:15 PM
If you want clear-headed and accessible reporting on AI incidents, this example is a gold standard.
Reposted by Antoine Taly
I will be in Geneva at #ECCB2026 for a super #glycotime workshop in glyco-bioinformatics hosted by @glycoexpasy.bsky.social to present a hands-on guide to the new layout and features of @glycoshape.org
If you want to hear all about it, just sign up! ⬇️
eccb2026.org/communities-... online and free
If you want to hear all about it, just sign up! ⬇️
eccb2026.org/communities-... online and free
September 2, 2026 at 1:54 PM
I will be in Geneva at #ECCB2026 for a super #glycotime workshop in glyco-bioinformatics hosted by @glycoexpasy.bsky.social to present a hands-on guide to the new layout and features of @glycoshape.org
If you want to hear all about it, just sign up! ⬇️
eccb2026.org/communities-... online and free
If you want to hear all about it, just sign up! ⬇️
eccb2026.org/communities-... online and free
Reposted by Antoine Taly
En septembre sur #TOTProts, les protéines font leur rentrée à l'usine !
#Vulgarisation #Protéines
topoftheprots.com/2024/11/25/r...
#Vulgarisation #Protéines
topoftheprots.com/2024/11/25/r...
September 1, 2026 at 7:31 AM
En septembre sur #TOTProts, les protéines font leur rentrée à l'usine !
#Vulgarisation #Protéines
topoftheprots.com/2024/11/25/r...
#Vulgarisation #Protéines
topoftheprots.com/2024/11/25/r...
Reposted by Antoine Taly
“Using research as an opportunity for learning-by-doing may produce seeming ‘inefficiencies,’ but that’s a feature, not a bug…the process of education is necessarily a productive struggle, and that the most important product of their education is not a GPA or a diploma but themselves“
Major kudos to MIT, who just put out a report about AI on their campus that lucidly explains the threat posed by AI to cognition and the student experience, while at the same time prioritizes learning, students, and the value of education. 1/x aiandeducation.mit.edu/report/
Report – AI and Education
aiandeducation.mit.edu
August 27, 2026 at 2:18 PM
“Using research as an opportunity for learning-by-doing may produce seeming ‘inefficiencies,’ but that’s a feature, not a bug…the process of education is necessarily a productive struggle, and that the most important product of their education is not a GPA or a diploma but themselves“
Reposted by Antoine Taly
Dernier dimanche des vacances...
Pourquoi ne pas le passer en science aux Étincelles Paris 15e ?
Au programme : Physique Chimie Biologie Astronomie (Planétarium) Géosciences et Informatique ⤵️
billetterie-etincelles.palais-decouverte.fr
Pourquoi ne pas le passer en science aux Étincelles Paris 15e ?
Au programme : Physique Chimie Biologie Astronomie (Planétarium) Géosciences et Informatique ⤵️
billetterie-etincelles.palais-decouverte.fr
August 30, 2026 at 6:30 AM
Dernier dimanche des vacances...
Pourquoi ne pas le passer en science aux Étincelles Paris 15e ?
Au programme : Physique Chimie Biologie Astronomie (Planétarium) Géosciences et Informatique ⤵️
billetterie-etincelles.palais-decouverte.fr
Pourquoi ne pas le passer en science aux Étincelles Paris 15e ?
Au programme : Physique Chimie Biologie Astronomie (Planétarium) Géosciences et Informatique ⤵️
billetterie-etincelles.palais-decouverte.fr
Reposted by Antoine Taly
Some exciting news: I'm joining the University of Lausanne @unil.bsky.social @dbc-unil.bsky.social as an Assistant Professor next month 🎉 My group will work on context-aware deep learning for protein structure, interaction & design. Postdoc and PhD openings coming soon - keep an eye out!
August 28, 2026 at 4:44 PM
Some exciting news: I'm joining the University of Lausanne @unil.bsky.social @dbc-unil.bsky.social as an Assistant Professor next month 🎉 My group will work on context-aware deep learning for protein structure, interaction & design. Postdoc and PhD openings coming soon - keep an eye out!
🚨 🚨New preprint from the group 🚨🚨
"Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? "
E Reboul shows you can split SMILES into fragments that follow retrosynthetic analysis!
with H Prabakaran J Waldispühl www.biorxiv.org/content/10.6...
"Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? "
E Reboul shows you can split SMILES into fragments that follow retrosynthetic analysis!
with H Prabakaran J Waldispühl www.biorxiv.org/content/10.6...
Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ?
Molecules generated by deep learning models are often difficult to synthesize. Their synthetic accessibility can be improved with automated retrosynthetic analysis, which allows for identifying syntho...
www.biorxiv.org
August 27, 2026 at 10:30 AM
🚨 🚨New preprint from the group 🚨🚨
"Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? "
E Reboul shows you can split SMILES into fragments that follow retrosynthetic analysis!
with H Prabakaran J Waldispühl www.biorxiv.org/content/10.6...
"Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? "
E Reboul shows you can split SMILES into fragments that follow retrosynthetic analysis!
with H Prabakaran J Waldispühl www.biorxiv.org/content/10.6...
Reposted by Antoine Taly
Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? [new]
SMILES sampling fragments molecules into ordered, concatenable blocks matching retrosynthons, improving break cov.
SMILES sampling fragments molecules into ordered, concatenable blocks matching retrosynthons, improving break cov.
August 27, 2026 at 4:53 AM
Can SMILES be fragmented into a concatenable ordered sequence of retrosynthetically interesting string block ? [new]
SMILES sampling fragments molecules into ordered, concatenable blocks matching retrosynthons, improving break cov.
SMILES sampling fragments molecules into ordered, concatenable blocks matching retrosynthons, improving break cov.
Reposted by Antoine Taly
Postdoc opportunity in my group! Please share! 🔁
Investigate the epigenetic mechanisms underlying stress memory in plants 🧬🌱
Looking for someone excited about computational genomics + plant molecular biology.
📍 Dundee, Scotland | 3 years
📅 Apply by 21 Sept
www.dundee.ac.uk/work-for-us/...
Investigate the epigenetic mechanisms underlying stress memory in plants 🧬🌱
Looking for someone excited about computational genomics + plant molecular biology.
📍 Dundee, Scotland | 3 years
📅 Apply by 21 Sept
www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - UOD2369
Closing date: Monday 21 September 2026, 23:59
www.dundee.ac.uk
August 24, 2026 at 8:25 AM
Postdoc opportunity in my group! Please share! 🔁
Investigate the epigenetic mechanisms underlying stress memory in plants 🧬🌱
Looking for someone excited about computational genomics + plant molecular biology.
📍 Dundee, Scotland | 3 years
📅 Apply by 21 Sept
www.dundee.ac.uk/work-for-us/...
Investigate the epigenetic mechanisms underlying stress memory in plants 🧬🌱
Looking for someone excited about computational genomics + plant molecular biology.
📍 Dundee, Scotland | 3 years
📅 Apply by 21 Sept
www.dundee.ac.uk/work-for-us/...
Reposted by Antoine Taly
🚨📣 Hiring a postdoc in bioinformatics 🧬🧑💻
Join our team at @i2bcparissaclay.bsky.social to explore biomolecular interactions and improve protein function prediction in bacteriophages!
📍 Gif-sur-Yvette, France
⏳ 13 months (+ possible extension)
📅 Apply here:
emploi.cnrs.fr/Offres/CDD/U...
Join our team at @i2bcparissaclay.bsky.social to explore biomolecular interactions and improve protein function prediction in bacteriophages!
📍 Gif-sur-Yvette, France
⏳ 13 months (+ possible extension)
📅 Apply here:
emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Job offer - Post-doctoral researcher in bioinformatics (M/F): exploring biomolecular interactions for bacteriophage protein function prediction
emploi.cnrs.fr
August 21, 2026 at 5:51 AM
🚨📣 Hiring a postdoc in bioinformatics 🧬🧑💻
Join our team at @i2bcparissaclay.bsky.social to explore biomolecular interactions and improve protein function prediction in bacteriophages!
📍 Gif-sur-Yvette, France
⏳ 13 months (+ possible extension)
📅 Apply here:
emploi.cnrs.fr/Offres/CDD/U...
Join our team at @i2bcparissaclay.bsky.social to explore biomolecular interactions and improve protein function prediction in bacteriophages!
📍 Gif-sur-Yvette, France
⏳ 13 months (+ possible extension)
📅 Apply here:
emploi.cnrs.fr/Offres/CDD/U...
Reposted by Antoine Taly
MEM-CALVADOS: A Residue-Level Model for Flexible Proteins at Membrane Interfaces https://www.biorxiv.org/content/10.64898/2026.08.12.743853v1
August 18, 2026 at 3:48 AM
MEM-CALVADOS: A Residue-Level Model for Flexible Proteins at Membrane Interfaces https://www.biorxiv.org/content/10.64898/2026.08.12.743853v1
Reposted by Antoine Taly
Postdoc Opportunity at McGill University, Montreal, Canada
You have worked with Arabidopsis / other plant model systems & are trained in high-end imaging?
Details: www.plantbiomechanics.net/joining-the-...
#plants, #Arabidopsis, #postdoc, #jobs, #microscopy, #confocal, #molecularbiology
You have worked with Arabidopsis / other plant model systems & are trained in high-end imaging?
Details: www.plantbiomechanics.net/joining-the-...
#plants, #Arabidopsis, #postdoc, #jobs, #microscopy, #confocal, #molecularbiology
August 17, 2026 at 2:06 PM
Postdoc Opportunity at McGill University, Montreal, Canada
You have worked with Arabidopsis / other plant model systems & are trained in high-end imaging?
Details: www.plantbiomechanics.net/joining-the-...
#plants, #Arabidopsis, #postdoc, #jobs, #microscopy, #confocal, #molecularbiology
You have worked with Arabidopsis / other plant model systems & are trained in high-end imaging?
Details: www.plantbiomechanics.net/joining-the-...
#plants, #Arabidopsis, #postdoc, #jobs, #microscopy, #confocal, #molecularbiology
Reposted by Antoine Taly
Arabidopsis Col-0 is not one thing "Genetic and epigenetic divergence among Arabidopsis thaliana Col-0 laboratory lineages since the 1950s". #PlantScience
From: www.biorxiv.org/content/10.6...
From: www.biorxiv.org/content/10.6...
Genetic and epigenetic divergence among Arabidopsis thaliana Col-0 laboratory lineages since the 1950s
The model plant Arabidopsis thaliana has been a workhorse of plant biology since the 1950s, when the Columbia-0 (Col-0) accession was widely adopted by the research community as a reference genotype. ...
www.biorxiv.org
August 15, 2026 at 2:21 PM
Arabidopsis Col-0 is not one thing "Genetic and epigenetic divergence among Arabidopsis thaliana Col-0 laboratory lineages since the 1950s". #PlantScience
From: www.biorxiv.org/content/10.6...
From: www.biorxiv.org/content/10.6...
Reposted by Antoine Taly
🐸 🐜 🪳 Pour les enfants dès 6 ans aux Étincelles du Palais, vous avez aujourd'hui un exposé sur les grenouilles à 10h20 et un atelier "dessine-moi les fourmis" à 11h40.
Demain dimanche en plus : les insectes et les fourmis 😉
➡️ billetterie-etincelles.palais-decouverte.fr
Demain dimanche en plus : les insectes et les fourmis 😉
➡️ billetterie-etincelles.palais-decouverte.fr
August 15, 2026 at 6:00 AM
🐸 🐜 🪳 Pour les enfants dès 6 ans aux Étincelles du Palais, vous avez aujourd'hui un exposé sur les grenouilles à 10h20 et un atelier "dessine-moi les fourmis" à 11h40.
Demain dimanche en plus : les insectes et les fourmis 😉
➡️ billetterie-etincelles.palais-decouverte.fr
Demain dimanche en plus : les insectes et les fourmis 😉
➡️ billetterie-etincelles.palais-decouverte.fr
Reposted by Antoine Taly
As promised, we now share some details why it took 32 months to get this Matters Arising published, and, since many asked, share some comments on the reply to our critique. All details can be found in this small FAQ vincentholst.github.io/the_curious_.... Below is a summary 🧵
August 14, 2026 at 3:20 PM
As promised, we now share some details why it took 32 months to get this Matters Arising published, and, since many asked, share some comments on the reply to our critique. All details can be found in this small FAQ vincentholst.github.io/the_curious_.... Below is a summary 🧵
Reposted by Antoine Taly
Pour l'été je vous offre un best-of de mes articles et chroniques, sous forme de feuilleton. Aujourd'hui:
ramus-meninges.fr/television-e...
ramus-meninges.fr/television-e...
L’exposition à la télévision et le test du bonhomme
par Magali Lavielle-Guida, Jonathan Bernard et Franck Ramus Synthèse grand public d’un article publié dans ANAE : Lavielle-Guida, M., Bernard, J. Y., & Ramus, F. (2022). Effets des écrans sur l…
ramus-meninges.fr
August 10, 2026 at 5:30 AM
Pour l'été je vous offre un best-of de mes articles et chroniques, sous forme de feuilleton. Aujourd'hui:
ramus-meninges.fr/television-e...
ramus-meninges.fr/television-e...