Çağrı Çevrim
@cagricevrim.bsky.social
regeneration | evo-devo | menstruation
Postdoc @ Harvard SCRB
Former BIF PhD fellow @ IGFL (Lyon, FR)
BSc & MSc @ Boğaziçi University (Ist, TR)
Postdoc @ Harvard SCRB
Former BIF PhD fellow @ IGFL (Lyon, FR)
BSc & MSc @ Boğaziçi University (Ist, TR)
Pinned
Çağrı Çevrim
@cagricevrim.bsky.social
· Oct 10
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Reposted by Çağrı Çevrim
PhyloPic is having an October fundraiser. The goal is to raise enough money to cover web hosting for the past six months. Please share the link, and chip in a bit if you can! www.phylopic.org
PhyloPic
PhyloPic is an open database of free silhouette images of animals, plants, and other life forms, available for reuse under Creative Commons licenses. Download silhouettes for use in educational materi...
www.phylopic.org
October 1, 2026 at 3:29 PM
PhyloPic is having an October fundraiser. The goal is to raise enough money to cover web hosting for the past six months. Please share the link, and chip in a bit if you can! www.phylopic.org
Your favorite website for illustrations of almost all organisms is looking for donations to help cover its running costs!
Please consider donating to help keep this open-source platform running:
www.phylopic.org/images
Please consider donating to help keep this open-source platform running:
www.phylopic.org/images
All Silhouette Images on PhyloPic
Browse all the free silhouette images in PhyloPic.
www.phylopic.org
October 1, 2026 at 2:48 PM
Your favorite website for illustrations of almost all organisms is looking for donations to help cover its running costs!
Please consider donating to help keep this open-source platform running:
www.phylopic.org/images
Please consider donating to help keep this open-source platform running:
www.phylopic.org/images
Reposted by Çağrı Çevrim
This is awful to hear, describing how Sean Eddy (HMMER, infernal, pfam, rfam) has been defunded. The letter said his work
"had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated,"
www.npr.org/2026/05/21/n...
"had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated,"
www.npr.org/2026/05/21/n...
Researchers say the Trump administration is finding new ways to punish science
Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.
www.npr.org
May 25, 2026 at 5:53 PM
This is awful to hear, describing how Sean Eddy (HMMER, infernal, pfam, rfam) has been defunded. The letter said his work
"had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated,"
www.npr.org/2026/05/21/n...
"had been determined to be of absolutely no value to the US taxpayer, and therefore it was being specifically terminated,"
www.npr.org/2026/05/21/n...
Reposted by Çağrı Çevrim
🚨 We discovered a new mode of Hox gene regulation in annelids! 🪱 A distal enhancer acts as a "global control region", lifting Hox genes from Polycomb repression. This is reminiscent of Hox gene control in vertebrates, but the two modes likely evolved convergently.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
May 19, 2026 at 8:09 PM
🚨 We discovered a new mode of Hox gene regulation in annelids! 🪱 A distal enhancer acts as a "global control region", lifting Hox genes from Polycomb repression. This is reminiscent of Hox gene control in vertebrates, but the two modes likely evolved convergently.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Çağrı Çevrim
Please don't post your preprints without material and methods @biorxivpreprint.bsky.social
May 6, 2026 at 9:09 AM
Please don't post your preprints without material and methods @biorxivpreprint.bsky.social
Reposted by Çağrı Çevrim
🔬 Diverse species. Stem cells. Highly international team. 🐸🐭
We’re looking for a Technical Assistant to join our stem cell–based research.
Interested?
Apply here 👉 jobs.tue.mpg.de/jobs/276
We’re looking for a Technical Assistant to join our stem cell–based research.
Interested?
Apply here 👉 jobs.tue.mpg.de/jobs/276
Online Application System - Max Planck Campus Tübingen
jobs.tue.mpg.de
April 30, 2026 at 10:19 AM
🔬 Diverse species. Stem cells. Highly international team. 🐸🐭
We’re looking for a Technical Assistant to join our stem cell–based research.
Interested?
Apply here 👉 jobs.tue.mpg.de/jobs/276
We’re looking for a Technical Assistant to join our stem cell–based research.
Interested?
Apply here 👉 jobs.tue.mpg.de/jobs/276
Reposted by Çağrı Çevrim
Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...
www.biorxiv.org
May 3, 2026 at 6:31 PM
Very excited to share our newest findings! A very long team effort pursued by multiple team members -to frantically reproduce everything over and over-, we show mTOR-Polycomb synergy at promoters of developmental master regulator TFs in ESCs prior to their expression. www.biorxiv.org/content/10.6...
Reposted by Çağrı Çevrim
we're on the cover!
April 30, 2026 at 2:08 PM
we're on the cover!
Reposted by Çağrı Çevrim
One of my recent commissions: "Weird Yet Thriving," naked mole rat edition!
#weird #nakedmolerat #biology #SciArt
#weird #nakedmolerat #biology #SciArt
April 24, 2026 at 10:45 PM
One of my recent commissions: "Weird Yet Thriving," naked mole rat edition!
#weird #nakedmolerat #biology #SciArt
#weird #nakedmolerat #biology #SciArt
Reposted by Çağrı Çevrim
I'm now on Bluesky!🤗 Excited to share our preprint, reviving
Kristy Red-Horse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
Kristy Red-Horse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
3D imaging of the pregnant uterus reveals an extensively invasive mouse placenta requiring CXCL12-CXCR4 signaling https://www.biorxiv.org/content/10.64898/2026.04.06.716785v1
April 11, 2026 at 11:26 PM
I'm now on Bluesky!🤗 Excited to share our preprint, reviving
Kristy Red-Horse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
Kristy Red-Horse's interest in the placenta from her PhD ~20 years ago! We find using 3D imaging that the mouse placenta is far more invasive than previously thought. Furthermore, we find a surprise from our favorite chemokine CXCL12...🧵:
Reposted by Çağrı Çevrim
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...
www.science.org
April 10, 2026 at 6:30 AM
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo
Reposted by Çağrı Çevrim
first part of my phd work is now available on bioRxiv!
NK cell receptor repertoires evolve under increased constraint butare not more diverse in menstruating mammals https://www.biorxiv.org/content/10.64898/2026.03.05.709850v1
March 11, 2026 at 7:03 PM
first part of my phd work is now available on bioRxiv!
Reposted by Çağrı Çevrim
1st McKinley Lab grad student’s 1st preprint!
@claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy.
Come for her GORGEOUS images, stay for her incredible discoveries.
www.biorxiv.org/content/10.6...
w/ @akelleher1017.bsky.social
@claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy.
Come for her GORGEOUS images, stay for her incredible discoveries.
www.biorxiv.org/content/10.6...
w/ @akelleher1017.bsky.social
March 12, 2026 at 6:10 PM
1st McKinley Lab grad student’s 1st preprint!
@claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy.
Come for her GORGEOUS images, stay for her incredible discoveries.
www.biorxiv.org/content/10.6...
w/ @akelleher1017.bsky.social
@claireang.bsky.social studied how the uterus safely excises massive amounts of tissue during menstruation and pregnancy.
Come for her GORGEOUS images, stay for her incredible discoveries.
www.biorxiv.org/content/10.6...
w/ @akelleher1017.bsky.social
Look at this amazing study from @claireang.bsky.social on uterus regeneration!
Very happy and proud to contribute...
Very happy and proud to contribute...
Excited to share my new preprint from the McKinley lab, where we explored regenerative mechanisms across menstruation and pregnancy! We thought specialized glands would regenerate everything.
We were wrong.
But the real mechanism turned out to be way cooler :) 🧪🧵
www.biorxiv.org/content/10.6...
We were wrong.
But the real mechanism turned out to be way cooler :) 🧪🧵
www.biorxiv.org/content/10.6...
www.biorxiv.org
March 12, 2026 at 11:06 PM
Look at this amazing study from @claireang.bsky.social on uterus regeneration!
Very happy and proud to contribute...
Very happy and proud to contribute...
These are absolutely amazing!
I have a new favorite journal...
I have a new favorite journal...
Just discovered the wonderful covers of 'Genes to Cells', the journal of the Molecular Biology Society of Japan @mbsj-official.bsky.social – absolutely beautiful!
here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments
here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments
March 9, 2026 at 11:42 PM
These are absolutely amazing!
I have a new favorite journal...
I have a new favorite journal...
Reposted by Çağrı Çevrim
In animals with large genomes, finding cis-regulatory elements can be very challenging. Enhancers can be located tens/hundreds of kb away from their target promoters. We face this challenge in Parhyale, with >3 Gbp genome.
We just published a preprint describing how we are tackling this problem. /1
We just published a preprint describing how we are tackling this problem. /1
www.biorxiv.org
March 9, 2026 at 9:38 AM
In animals with large genomes, finding cis-regulatory elements can be very challenging. Enhancers can be located tens/hundreds of kb away from their target promoters. We face this challenge in Parhyale, with >3 Gbp genome.
We just published a preprint describing how we are tackling this problem. /1
We just published a preprint describing how we are tackling this problem. /1
Reposted by Çağrı Çevrim
Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
The molecular evolution of vertebrate organs
Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...
rdcu.be
February 25, 2026 at 12:29 PM
Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
February 23, 2026 at 5:16 PM
Reposted by Çağrı Çevrim
Previously we had shown that axolotl tail regeneration occurs in the absence of somitogenesis. In the updated manuscript we propose that vertebral segmentation during tail regeneration occurs through a process of buckling instability. www.biorxiv.org/content/10.1...
January 31, 2026 at 3:05 PM
Previously we had shown that axolotl tail regeneration occurs in the absence of somitogenesis. In the updated manuscript we propose that vertebral segmentation during tail regeneration occurs through a process of buckling instability. www.biorxiv.org/content/10.1...
Reposted by Çağrı Çevrim
Our new paper reveals critical new regulators of stem cell differentiation that control where the right kinds of cells are made in planarians.
In particular, we find Anosmin—a gene responsible for Kallmann Syndrome—as a restrictor of neurogenesis.
www.nature.com/articles/s41...
#basicresearch
In particular, we find Anosmin—a gene responsible for Kallmann Syndrome—as a restrictor of neurogenesis.
www.nature.com/articles/s41...
#basicresearch
January 28, 2026 at 2:20 AM
Our new paper reveals critical new regulators of stem cell differentiation that control where the right kinds of cells are made in planarians.
In particular, we find Anosmin—a gene responsible for Kallmann Syndrome—as a restrictor of neurogenesis.
www.nature.com/articles/s41...
#basicresearch
In particular, we find Anosmin—a gene responsible for Kallmann Syndrome—as a restrictor of neurogenesis.
www.nature.com/articles/s41...
#basicresearch
Reposted by Çağrı Çevrim
In preprints: shedding light – chemogenetic induction of menstruation in mice
Aishwarya V. Bhurke and Ripla Arora from @aroralab.bsky.social discuss the recent preprint by @cagricevrim.bsky.social, @karalmckinley.bsky.social and colleagues on the X-mens menstruation model.
doi.org/10.1242/dev....
Aishwarya V. Bhurke and Ripla Arora from @aroralab.bsky.social discuss the recent preprint by @cagricevrim.bsky.social, @karalmckinley.bsky.social and colleagues on the X-mens menstruation model.
doi.org/10.1242/dev....
January 27, 2026 at 2:48 PM
In preprints: shedding light – chemogenetic induction of menstruation in mice
Aishwarya V. Bhurke and Ripla Arora from @aroralab.bsky.social discuss the recent preprint by @cagricevrim.bsky.social, @karalmckinley.bsky.social and colleagues on the X-mens menstruation model.
doi.org/10.1242/dev....
Aishwarya V. Bhurke and Ripla Arora from @aroralab.bsky.social discuss the recent preprint by @cagricevrim.bsky.social, @karalmckinley.bsky.social and colleagues on the X-mens menstruation model.
doi.org/10.1242/dev....
Reposted by Çağrı Çevrim
I am looking for two postdocs to join our lab
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
January 9, 2026 at 3:17 PM
I am looking for two postdocs to join our lab
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
- One (bio)image analyst
- One cell biologist interested to work on lymphatics!
The positions will open soon, be in touch!
Reposted by Çağrı Çevrim
PhD position(s)🚨deadline 20th Jan
1-development of brain & behaviour in the precocial spiny mouse tinyurl.com/yaxhy5y2
2-social behaviour & neurophysiology in a menstruating rodent using AI tinyurl.com/ykv93cts
apply ✍️
@ai4bicdt.bsky.social @sidb-edinburgh.bsky.social @edinunineuro.bsky.social
1-development of brain & behaviour in the precocial spiny mouse tinyurl.com/yaxhy5y2
2-social behaviour & neurophysiology in a menstruating rodent using AI tinyurl.com/ykv93cts
apply ✍️
@ai4bicdt.bsky.social @sidb-edinburgh.bsky.social @edinunineuro.bsky.social
January 8, 2026 at 5:43 PM
PhD position(s)🚨deadline 20th Jan
1-development of brain & behaviour in the precocial spiny mouse tinyurl.com/yaxhy5y2
2-social behaviour & neurophysiology in a menstruating rodent using AI tinyurl.com/ykv93cts
apply ✍️
@ai4bicdt.bsky.social @sidb-edinburgh.bsky.social @edinunineuro.bsky.social
1-development of brain & behaviour in the precocial spiny mouse tinyurl.com/yaxhy5y2
2-social behaviour & neurophysiology in a menstruating rodent using AI tinyurl.com/ykv93cts
apply ✍️
@ai4bicdt.bsky.social @sidb-edinburgh.bsky.social @edinunineuro.bsky.social
Reposted by Çağrı Çevrim
Do YOU live with joint pain?
Do YOU experience poor pain management?
Have you got 2-minutes to tell pain researchers about it?
If yes 👉 forms.gle/7NTwma2gnVN1...
We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃
Do YOU experience poor pain management?
Have you got 2-minutes to tell pain researchers about it?
If yes 👉 forms.gle/7NTwma2gnVN1...
We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃
December 20, 2025 at 9:57 AM
Do YOU live with joint pain?
Do YOU experience poor pain management?
Have you got 2-minutes to tell pain researchers about it?
If yes 👉 forms.gle/7NTwma2gnVN1...
We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃
Do YOU experience poor pain management?
Have you got 2-minutes to tell pain researchers about it?
If yes 👉 forms.gle/7NTwma2gnVN1...
We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃
Reposted by Çağrı Çevrim
I can only second this. BUT, what people often are not aware of: Frontiers in Zoology does NOT belong to the rest of the Frontiers in journals. It is the official journal of the German Zoological Society, a BMC journal and founded BEFORE the other Front in. We suffer a lot from this hijacking.
December 21, 2025 at 1:50 PM
I can only second this. BUT, what people often are not aware of: Frontiers in Zoology does NOT belong to the rest of the Frontiers in journals. It is the official journal of the German Zoological Society, a BMC journal and founded BEFORE the other Front in. We suffer a lot from this hijacking.