Horacio V. Guzman
@gocompmodeling.bsky.social
Physicist and engineer, into multiple scale models of proteins/RNA/membranes, polymers, scientific computing, more --> http://tinyurl.com/goCompModeling
Awesome, congrats!
No predefined reaction coordinate. No mechanistic guesswork. No massive sampling campaign. Gen-COMPAS reconstructs biomolecular transition pathways from endpoint structures alone. Protein folding, allostery, membrane transport. Now in Nature.
@nature.com @springernature.com
@nature.com @springernature.com
September 14, 2026 at 10:24 AM
Awesome, congrats!
Reposted by Horacio V. Guzman
Reposted by Horacio V. Guzman
If you're in Chicago at the @acs.org meeting, check out these events with @mdanalysis.bsky.social folks.
For Day 3 of MDAnalysis in Chicago, Core Developers are taking a short break. But the MDAnalysis fun will begin again tomorrow (Aug 27) with 2 events you won't want to miss:
🔸 @omsf.io Stack Tour | 🕐 11-11:45 AM | 🔗 events.omsf.io
🔸 MDAnalysis Meetup | 🕐 6-9 PM | 🔗 forms.gle/VNKuYuWwurLB...
🔸 @omsf.io Stack Tour | 🕐 11-11:45 AM | 🔗 events.omsf.io
🔸 MDAnalysis Meetup | 🕐 6-9 PM | 🔗 forms.gle/VNKuYuWwurLB...
August 26, 2026 at 11:22 PM
If you're in Chicago at the @acs.org meeting, check out these events with @mdanalysis.bsky.social folks.
Awesome, congrats!
Molecular architecture of colossal surface layers from hyperthermophilic archaea
Led by @idocaspy.bsky.social (Ido)
In collaboration with @mkrupovic.bsky.social and @vikramalva.bsky.social labs
doi.org/10.64898/202...
Led by @idocaspy.bsky.social (Ido)
In collaboration with @mkrupovic.bsky.social and @vikramalva.bsky.social labs
doi.org/10.64898/202...
August 24, 2026 at 9:52 AM
Awesome, congrats!
👇
Against all odds, with an HHS that has defunded mRNA research programs, the FDA just approved the first mRNA flu vaccine
August 6, 2026 at 9:27 AM
👇
Reposted by Horacio V. Guzman
PhD position in Heidelberg: generating amorphous molecular thin films with diffusion models rather than waiting for MD to equilibrate them — free energies from the same model. With U. Köthe. 3 years, funded. Physics degree required.
tristanbereau.com/positions/ge...
tristanbereau.com/positions/ge...
Generative machine learning for molecular thin films – Tristan Bereau
tristanbereau.com
August 3, 2026 at 9:47 AM
PhD position in Heidelberg: generating amorphous molecular thin films with diffusion models rather than waiting for MD to equilibrate them — free energies from the same model. With U. Köthe. 3 years, funded. Physics degree required.
tristanbereau.com/positions/ge...
tristanbereau.com/positions/ge...
Reposted by Horacio V. Guzman
Come join the new Novo Nordisk Foundation Center for Protein Design as a group leader
Cool science in a great scientific environment in wonderful and very family friendly Copenhagen
There are two positions that can either be at TT assistant or associate prof level
employment.ku.dk/tenure-track...
Cool science in a great scientific environment in wonderful and very family friendly Copenhagen
There are two positions that can either be at TT assistant or associate prof level
employment.ku.dk/tenure-track...
Tenure-track Assistant Professor or Associate Professor of De novo Protein Design
The Novo Nordisk Foundation Center for Protein Design at the University of Copenhagen seeks to appoint two new group leaders in de novo protein design from 1 February 2027 or as soon as possible thereafter. These positions will be at the Assistant or Associate Professor level and associated with the Department of Biology (Faculty of Science) or the Department of Drug Design and Pharmacology (Faculty of Health and Medical Sciences).
employment.ku.dk
June 23, 2026 at 8:52 PM
Come join the new Novo Nordisk Foundation Center for Protein Design as a group leader
Cool science in a great scientific environment in wonderful and very family friendly Copenhagen
There are two positions that can either be at TT assistant or associate prof level
employment.ku.dk/tenure-track...
Cool science in a great scientific environment in wonderful and very family friendly Copenhagen
There are two positions that can either be at TT assistant or associate prof level
employment.ku.dk/tenure-track...
🔊don't miss it!
On Thursday we look forward to hosting Sereina Riniker (ETH Zürich) for the last AI4Science seminar of the academic year. Don't miss it! At 15:00 CEST 🇸🇪 in EDIT Analysen at Chalmers, and online. See link below for details:
www.chalmers.se/en/current/c...
Co-organized with @smnlssn.bsky.social
www.chalmers.se/en/current/c...
Co-organized with @smnlssn.bsky.social
June 9, 2026 at 2:45 PM
🔊don't miss it!
Cool... such a multifunctional molecule also in its ds version!🧬
"RNA-binding of the adaptor complex is provided by Egl that engages targets by assembling multiple, atypical RNA-binding domains around double-stranded RNA stem loops (..) the shape of those is critical for recognition" (edited)
@cellbiol-mrclmb.bsky.social
*Wow* 🧪😎
share.google/b2QWuHfDo707...
@cellbiol-mrclmb.bsky.social
*Wow* 🧪😎
share.google/b2QWuHfDo707...
The hidden rules of mRNA transport | MRC Laboratory of Molecular Biology
A collaborative study from the groups of Simon Bullock and Andrew Carter (Cell Biology and Structural Studies Divisions) has found a structural code that ex ...
share.google
May 10, 2026 at 4:04 PM
Cool... such a multifunctional molecule also in its ds version!🧬
Reposted by Horacio V. Guzman
Join us for PSA 2026!
We are excited to announce the Peptide Self-Assembly Conference — From Dynamic Structures to Functional Materials — hosted by MPIP & JGU Mainz.
📍 Mainz, Germany | Aug 10–12, 2026
📅 Abstract deadline: June 10
🔗 Register here: www.psacon2026.com
#PSA2026 @mpip-mainz.mpg.de
We are excited to announce the Peptide Self-Assembly Conference — From Dynamic Structures to Functional Materials — hosted by MPIP & JGU Mainz.
📍 Mainz, Germany | Aug 10–12, 2026
📅 Abstract deadline: June 10
🔗 Register here: www.psacon2026.com
#PSA2026 @mpip-mainz.mpg.de
May 6, 2026 at 11:06 AM
Join us for PSA 2026!
We are excited to announce the Peptide Self-Assembly Conference — From Dynamic Structures to Functional Materials — hosted by MPIP & JGU Mainz.
📍 Mainz, Germany | Aug 10–12, 2026
📅 Abstract deadline: June 10
🔗 Register here: www.psacon2026.com
#PSA2026 @mpip-mainz.mpg.de
We are excited to announce the Peptide Self-Assembly Conference — From Dynamic Structures to Functional Materials — hosted by MPIP & JGU Mainz.
📍 Mainz, Germany | Aug 10–12, 2026
📅 Abstract deadline: June 10
🔗 Register here: www.psacon2026.com
#PSA2026 @mpip-mainz.mpg.de
What's the role of glycans during adsorption on polarizable surfaces? Our work shows "dual capacity" acting either as a glue that enhances glycoprotein adsorption strength through dynamic-tethering patterns or as a blocking element that prevents protein-surface interactions #compchem @pubs.acs.org
March 11, 2026 at 3:47 AM
What's the role of glycans during adsorption on polarizable surfaces? Our work shows "dual capacity" acting either as a glue that enhances glycoprotein adsorption strength through dynamic-tethering patterns or as a blocking element that prevents protein-surface interactions #compchem @pubs.acs.org
Reposted by Horacio V. Guzman
Our latest paper in which we use multiple force fields to recover various conformations of the ribose transporter from E. coli. The work of DPhil student Nikolai Juraschko and postdoc Florencia Klein Rocha
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Characterizing the Conformational Dynamics of the Ribose Transporter B Protein in Escherichia coli: Enhanced Sampling via Multiple Force Fields
We present a molecular dynamics simulation study of the E. coli ribose transporter protein B (RbsB), a conformationally labile protein found in the periplasm of the bacterium. The ribose transporter e...
pubs.acs.org
March 10, 2026 at 4:33 PM
Our latest paper in which we use multiple force fields to recover various conformations of the ribose transporter from E. coli. The work of DPhil student Nikolai Juraschko and postdoc Florencia Klein Rocha
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Horacio V. Guzman
#PhDPosition open — #RibosomeBiology & #Translation QC
📍 JGU Mainz, Germany
🗓️ Apply by 10 Mar 2026 (or until filled)
🔗 Full details + project options:
👉 ak-winz.pharmazie.uni-mainz.de/jobs/
📍 JGU Mainz, Germany
🗓️ Apply by 10 Mar 2026 (or until filled)
🔗 Full details + project options:
👉 ak-winz.pharmazie.uni-mainz.de/jobs/
Jobs/internships/theses | Winz Lab - AK Winz
ak-winz.pharmazie.uni-mainz.de
February 10, 2026 at 8:02 AM
#PhDPosition open — #RibosomeBiology & #Translation QC
📍 JGU Mainz, Germany
🗓️ Apply by 10 Mar 2026 (or until filled)
🔗 Full details + project options:
👉 ak-winz.pharmazie.uni-mainz.de/jobs/
📍 JGU Mainz, Germany
🗓️ Apply by 10 Mar 2026 (or until filled)
🔗 Full details + project options:
👉 ak-winz.pharmazie.uni-mainz.de/jobs/
Reposted by Horacio V. Guzman
My little outlook on how our lungs 🫁 are like the sea 🌊 is finally out in Central Science. Thanks to the support from incredible mentors @rommieamaro.bsky.social and @kprather.bsky.social !!
A new review explores one of the themes of my book Air-Borne: our lungs are like the ocean. Both send life into the atmosphere. pubs.acs.org/doi/full/10....
December 11, 2025 at 12:18 PM
My little outlook on how our lungs 🫁 are like the sea 🌊 is finally out in Central Science. Thanks to the support from incredible mentors @rommieamaro.bsky.social and @kprather.bsky.social !!
Not yet there for extracting a 3D model from a "picture image" and applying it to our #Proteins, #chompchmesky , #compchem; @Meta the protein was flatenned in the depth direction, otherwise would be great to track some Multiscale model AI mappings, and much more 🧬 🧶🪱
November 24, 2025 at 2:12 PM
Not yet there for extracting a 3D model from a "picture image" and applying it to our #Proteins, #chompchmesky , #compchem; @Meta the protein was flatenned in the depth direction, otherwise would be great to track some Multiscale model AI mappings, and much more 🧬 🧶🪱
Thanks to the organizers for giving me the opportunity to present my lab' top-notch RNA models at multiple scales, including polymer physics(⚡ electrostatic and 🍦 mechanical properties) inputs and features of structural predictions with AI 🧵! #RNAtime #RNApuzzles #RNAmultiscaleSims #rnaProtInteract
Last Friday, we had an inspiring 10th Rhineland RNA Club meeting with top class speakers. It's great to see how the community is growing and the range of topics we're covering. Special thanks to Didier Stainier @stainierlab.bsky.social Simon Bekker-Jensen @bekkerjensenlab.bsky.social, Ranen Aviner!
November 19, 2025 at 12:47 PM
Thanks to the organizers for giving me the opportunity to present my lab' top-notch RNA models at multiple scales, including polymer physics(⚡ electrostatic and 🍦 mechanical properties) inputs and features of structural predictions with AI 🧵! #RNAtime #RNApuzzles #RNAmultiscaleSims #rnaProtInteract
Reposted by Horacio V. Guzman
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 17, 2025 at 8:51 AM
Are you a postdoc stuck in the US?! Is your research stalled or are you in any way affected by the whims of that unfettered madman? Interested in MD simulations of large biomolecules?!
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
Consider joining me at the University of Freiburg!
uni-freiburg.de/frias/call-f...
BA.3.2 in Rheinland Pfalz 🇩🇪... most likely Hessen too... #compchemsky, #compchem, #goViralAgain #physVirology #compVirology
Tracking SARSCoV2 Lineage BA.3.2* over time
Total BA.3.2* - Globally: 63
Countries reporting BA.3.2*: #Australia, #SouthAfrica, #Netherlands, #USA (traveler seq), #Germany, #Mozambique, #Slovenia, #UK, #Denmark
Tracker: public.tableau.com/app/profile/...
Total BA.3.2* - Globally: 63
Countries reporting BA.3.2*: #Australia, #SouthAfrica, #Netherlands, #USA (traveler seq), #Germany, #Mozambique, #Slovenia, #UK, #Denmark
Tracker: public.tableau.com/app/profile/...
November 10, 2025 at 4:01 PM
BA.3.2 in Rheinland Pfalz 🇩🇪... most likely Hessen too... #compchemsky, #compchem, #goViralAgain #physVirology #compVirology
Reposted by Horacio V. Guzman
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: [email protected]
October 22, 2025 at 2:55 PM
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: [email protected]
📣 Check out our 𝔾𝕝𝕪𝕔𝕠-𝕒𝕕𝕤𝕠𝕣𝕡𝕥𝕚𝕠𝕟 on 𝔽𝕠𝕞𝕚𝕥𝕖𝕤
Preprint! doi.org/10.1101/2025... We highlight glycans’ dual capacity, to act either as a glue that dominates the whole glycoprotein adsorption strength via tethering, or as a blocking element preventing adsorption 1/2 #glycanResearch #glycanAsGlues 🩹🧵🦠
Preprint! doi.org/10.1101/2025... We highlight glycans’ dual capacity, to act either as a glue that dominates the whole glycoprotein adsorption strength via tethering, or as a blocking element preventing adsorption 1/2 #glycanResearch #glycanAsGlues 🩹🧵🦠
October 21, 2025 at 4:19 PM
📣 Check out our 𝔾𝕝𝕪𝕔𝕠-𝕒𝕕𝕤𝕠𝕣𝕡𝕥𝕚𝕠𝕟 on 𝔽𝕠𝕞𝕚𝕥𝕖𝕤
Preprint! doi.org/10.1101/2025... We highlight glycans’ dual capacity, to act either as a glue that dominates the whole glycoprotein adsorption strength via tethering, or as a blocking element preventing adsorption 1/2 #glycanResearch #glycanAsGlues 🩹🧵🦠
Preprint! doi.org/10.1101/2025... We highlight glycans’ dual capacity, to act either as a glue that dominates the whole glycoprotein adsorption strength via tethering, or as a blocking element preventing adsorption 1/2 #glycanResearch #glycanAsGlues 🩹🧵🦠
After 4 days of listening to top-notch experts in the field of glycoprotein/membrane interactions. I want to say big thanks to @rommieamaro.bsky.social @biophysmatt.bsky.social @rocovino.bsky.social and AtilioV & @giorgiocolombo.bsky.social for hosting me as a speaker and also poster presenter* 2!
September 10, 2025 at 4:58 PM
After 4 days of listening to top-notch experts in the field of glycoprotein/membrane interactions. I want to say big thanks to @rommieamaro.bsky.social @biophysmatt.bsky.social @rocovino.bsky.social and AtilioV & @giorgiocolombo.bsky.social for hosting me as a speaker and also poster presenter* 2!
awesome, and very helpful to the computational biophysist!🧶🪡
Research Briefing:
"Visualizing the nanostructure of the cell’s sugar coat."
Here, the author's views, expert opinion, and insights behind the recently published paper "Ångström-resolution imaging of cell-surface glycans" are presented.
#Glycotime
www.nature.com/articles/s41...
"Visualizing the nanostructure of the cell’s sugar coat."
Here, the author's views, expert opinion, and insights behind the recently published paper "Ångström-resolution imaging of cell-surface glycans" are presented.
#Glycotime
www.nature.com/articles/s41...
August 6, 2025 at 12:23 PM
awesome, and very helpful to the computational biophysist!🧶🪡
Participate in Capri, BTW are glycan-protein complexes also tackled?
A small reminder to all structural biologists around working on biomolecular complexes: please consider sharing your complexes as targets for CAPRI - AI has not solved all structure prediction problems and there are still challenges! See www.capri-docking.org/contribute/
CAPRI Docking
www.capri-docking.org
July 29, 2025 at 9:39 AM
Participate in Capri, BTW are glycan-protein complexes also tackled?
Are you studying biophysical phenomena @interfaces ? Then check-out our newest toolbox doi.org/10.1016/j.bp..., featuring membranes and biopolymers (basic+advanced) analyses in 2D! 🫓 🏄 🦠🧬🧶 🪢Awesome Collab with @vmonje.bsky.social 's group! Video intro HERE!
June 30, 2025 at 2:08 PM
Are you studying biophysical phenomena @interfaces ? Then check-out our newest toolbox doi.org/10.1016/j.bp..., featuring membranes and biopolymers (basic+advanced) analyses in 2D! 🫓 🏄 🦠🧬🧶 🪢Awesome Collab with @vmonje.bsky.social 's group! Video intro HERE!
Indeed exciting and intense conf. with an awesome speaker line-up. And many online questions 🪢🧶🧬🧵🙋#multiscaleRNA #compchem
Almost at the end of the exciting @cecamevents.bsky.social conference 'RNA Modelling across scales' at SISSA, Trieste, Italy! 🎉 Fantastic speakers and great science. Organized with @bussigio.bsky.social @marcodevivo.bsky.social #RNA
May 23, 2025 at 12:31 PM
Indeed exciting and intense conf. with an awesome speaker line-up. And many online questions 🪢🧶🧬🧵🙋#multiscaleRNA #compchem