Gregor lab
@gregorlab.bsky.social
@imgprague research group studying cytoskeleton organization in cell and tissue mechanics. Tweets by Martin Gregor and lab members. #mechanobiology
https://www.img.cas.cz/group/martin-gregor/
https://www.img.cas.cz/group/martin-gregor/
“Illuminating the Architecture of Thought” by our Postdoc @GemperleJakub (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats jakub! @imgprague imcf.natur.cuni.cz/IMCF/picture-o…#neurono#Live-cellll imaging of a mature primary neuron through microinjected GFP
July 21, 2026 at 4:10 PM
“Illuminating the Architecture of Thought” by our Postdoc @GemperleJakub (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats jakub! @imgprague imcf.natur.cuni.cz/IMCF/picture-o…#neurono#Live-cellll imaging of a mature primary neuron through microinjected GFP
“The Aquarelle of Motion” by our PhD student Vera Getmanchuk-Zaporoshchenko (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats Vera! imcf.natur.cuni.cz/IMCF/picture...
May 21, 2026 at 6:08 AM
“The Aquarelle of Motion” by our PhD student Vera Getmanchuk-Zaporoshchenko (@imgprague) has won the Prague @EuroBioImaging Node Picture of the Month. Congrats Vera! imcf.natur.cuni.cz/IMCF/picture...
@Gregor_lab #labretreat 2026: two days of exploring new angles of our projects, hiking, enjoying great food, and sharing lots of laughter in the beautiful scenery of Český ráj. Thanks to Vera, Káča, and Černá Louže for making it happen this year!
May 5, 2026 at 9:56 AM
@Gregor_lab #labretreat 2026: two days of exploring new angles of our projects, hiking, enjoying great food, and sharing lots of laughter in the beautiful scenery of Český ráj. Thanks to Vera, Káča, and Černá Louže for making it happen this year!
Happy to be part of this story: Jan Famera and Lea M. Skultéty from Gymnázium Karla Čapka in Dobříš advanced to the next round of Students’ Professional Activities, Czech national high-school research competition, with work on muscular dystrophy performed in our lab. Huge congratulations!
April 30, 2026 at 12:54 PM
Happy to be part of this story: Jan Famera and Lea M. Skultéty from Gymnázium Karla Čapka in Dobříš advanced to the next round of Students’ Professional Activities, Czech national high-school research competition, with work on muscular dystrophy performed in our lab. Huge congratulations!
Great @imgprague seminar by our PhD student Srikant Ojha @sojha148 on hepatic stellate cell #mechanosignaling and its potential for new therapeutic approaches in liver #fibrosis. Lab of Integrative Biology @Gregor_lab is leveling up 🚀
March 20, 2026 at 11:40 AM
Great @imgprague seminar by our PhD student Srikant Ojha @sojha148 on hepatic stellate cell #mechanosignaling and its potential for new therapeutic approaches in liver #fibrosis. Lab of Integrative Biology @Gregor_lab is leveling up 🚀
Reposted by Gregor lab
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
January 19, 2026 at 10:16 AM
🚀Open PhD position!
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Lab of Integrative Biology @gregorlab.bsky.social is seeking a new talent.
💪Ultimate goal: Develop AAV-compatible mini-plectins to treat muscular dystrophy and cardiomyopathy
👉Profile: MSc, interest in biology, motivation, independence
🧡APPLY: img.cas.cz/phd
Our paper on the anti-cancer effects of the first-in-class plectin inhibitor plecstatin is out in @MolOncology! Great work by @OutlaZuzana & @Kosla_Jan. Collaborations with @Selma_OsMyers (@MedUniWien), Sam Meier (@univienna) & Lukas Frick (@UZH). Check at pubmed.ncbi.nlm.nih.gov/41467448/
December 31, 2025 at 8:06 PM
Our paper on the anti-cancer effects of the first-in-class plectin inhibitor plecstatin is out in @MolOncology! Great work by @OutlaZuzana & @Kosla_Jan. Collaborations with @Selma_OsMyers (@MedUniWien), Sam Meier (@univienna) & Lukas Frick (@UZH). Check at pubmed.ncbi.nlm.nih.gov/41467448/
It’s been an eventful year for all of us! Our Christmas party was a great reminder of the team spirit behind the science & we’re excited to take on the challenges of 2026. Merry Christmas & Happy New Year from the Laboratory of Integrative Biology!
December 22, 2025 at 9:41 PM
It’s been an eventful year for all of us! Our Christmas party was a great reminder of the team spirit behind the science & we’re excited to take on the challenges of 2026. Merry Christmas & Happy New Year from the Laboratory of Integrative Biology!
At #WMS2025 in Vienna? Check out our PhD student Vera Getmanchuk-Zaporoshchenko’s poster on phenotyping a preclinical model of plectin-related LGMD. #LGMD #MuscularDystrophy"
October 9, 2025 at 10:40 AM
At #WMS2025 in Vienna? Check out our PhD student Vera Getmanchuk-Zaporoshchenko’s poster on phenotyping a preclinical model of plectin-related LGMD. #LGMD #MuscularDystrophy"
Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social
September 23, 2025 at 2:17 PM
Huge congrats to our PhD student, Piyush Bisht, for presenting his work on Flipper-TR probe applied to Circulating Tumor Cells at #Czechbioimaging's Imaging Principles of Life 2025 conference in Brno! He had amazing discussions and valuable feedback. Way to go, Piyush!" @imgprague.bsky.social
Two hours of tough work to make 2 minutes of science sparkle ✨ Today we helped popularize our #magnetogenetics manuscript by Gemperle Jakub for NUVR_CZ. Tune in to TV NOVA evening news!
September 3, 2025 at 1:52 PM
Two hours of tough work to make 2 minutes of science sparkle ✨ Today we helped popularize our #magnetogenetics manuscript by Gemperle Jakub for NUVR_CZ. Tune in to TV NOVA evening news!
“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; @gregorlab.bsky.social) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!
August 20, 2025 at 4:02 PM
“Cellfie: A triple-stained portrait of HeLa’s senescence” by Spoorthi Suresh Hiremath (@imgprague.bsky.social; @gregorlab.bsky.social) has won the Prague @eurobioimaging.bsky.social Node Picture of the Month. Congrats Spoorthi!
"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10....
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
Live-cell magnetic manipulation of recycling endosomes reveals their direct effect on actin protrusions to promote invasive migration
Repositioning of Rab25 vesicles containing formin and integrin cargos to the cell periphery promotes protrusion formation.
www.science.org
July 7, 2025 at 12:58 PM
"It's official 🎉: Our remote magnetic control of #endosomes, driving invasive protrusions in living cells, has landed in #ScienceAdvances! #Magnetogenetics meets #Rabs! The journey was wild, but it works! 🔥 www.science.org/doi/full/10....
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
@imgprague.bsky.social #3Dmatrix #CellBiology
@science.org
Huge congratulations to our PhD student Srikant Ojha for winning the Microscopic Picture of the Year 2024/2025 award! Well deserved!
June 25, 2025 at 1:34 PM
Huge congratulations to our PhD student Srikant Ojha for winning the Microscopic Picture of the Year 2024/2025 award! Well deserved!
30th Cytoskeletal Club was opened in Liblice on Monday, 28 April. The first day is complete - great keynote by Martijn Gloerich (@GloerichLab) from @UMCUtrecht on Mechanical control of epithelial cell division. More to come!
April 29, 2025 at 8:01 AM
30th Cytoskeletal Club was opened in Liblice on Monday, 28 April. The first day is complete - great keynote by Martijn Gloerich (@GloerichLab) from @UMCUtrecht on Mechanical control of epithelial cell division. More to come!
Great 2 days at MedUni Vienna hosted by @Selma_OsMyers from Institute of Medical Chemistry and Pathobiochemistry. Giving a seminar on our concept of targeting mechanical homeostasis in cancer. Great meeting the Lilli Winter and Osmanagic-Myers Labs. Evening with our mentor Gerhard Wiche.
April 27, 2025 at 10:06 PM
Great 2 days at MedUni Vienna hosted by @Selma_OsMyers from Institute of Medical Chemistry and Pathobiochemistry. Giving a seminar on our concept of targeting mechanical homeostasis in cancer. Great meeting the Lilli Winter and Osmanagic-Myers Labs. Evening with our mentor Gerhard Wiche.
Excited to share our new @elife.bsky.social in collaboration with @Schiller lab.: Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis doi.org/10.7554/eLif...
#ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics
#ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics
April 11, 2025 at 9:15 AM
Excited to share our new @elife.bsky.social in collaboration with @Schiller lab.: Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis doi.org/10.7554/eLif...
#ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics
#ECMatrix #chaperone #Clusterin #ECMresearch #Collagen #Integrin #AFM #Proteomics
Happy Monday... Happy to share the picture of our colleague Srikant Ojha winning EuBI Node Picture of the Month 2024/25 competition! (imcf.natur.cuni.cz/IMCF/picture...)
March 24, 2025 at 3:23 PM
Happy Monday... Happy to share the picture of our colleague Srikant Ojha winning EuBI Node Picture of the Month 2024/25 competition! (imcf.natur.cuni.cz/IMCF/picture...)
Excited to share our new @elife.bsky.social paper! We show that plectin fuels the growth & metastasis of hepatocellular carcinoma (HCC). Targeting plectin could be promising in HCC therapy, as we show using a novel plectin inhibitor, plecstatin! elifesciences.org/articles/102... #plectin #HCC
Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis
Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistan...
elifesciences.org
March 21, 2025 at 10:40 AM
Excited to share our new @elife.bsky.social paper! We show that plectin fuels the growth & metastasis of hepatocellular carcinoma (HCC). Targeting plectin could be promising in HCC therapy, as we show using a novel plectin inhibitor, plecstatin! elifesciences.org/articles/102... #plectin #HCC
Hello! The Martin Gregor lab @imgprague is now on Bluesky! We will tweet about our #mechanobiology work, pretty microscopy images and videos and more. FOLLOW us!
March 13, 2025 at 7:50 AM
Hello! The Martin Gregor lab @imgprague is now on Bluesky! We will tweet about our #mechanobiology work, pretty microscopy images and videos and more. FOLLOW us!