JAMA
@jama.com
JAMA is an international peer-reviewed general medical journal and a member of the JAMA Network family of journals.
🌐 JAMA.com
🌐 JAMA.com
💬 Viewpoint: As organ supply expands in #Transplantation, inequities may shift from waitlist ranking to who is referred, evaluated, listed, and able to access new technology.
ja.ma/4idNhIi
ja.ma/4idNhIi
October 12, 2026 at 3:45 PM
💬 Viewpoint: As organ supply expands in #Transplantation, inequities may shift from waitlist ranking to who is referred, evaluated, listed, and able to access new technology.
ja.ma/4idNhIi
ja.ma/4idNhIi
#JAMAReview: After #HeartTransplant, long-term outcomes depend on rejection surveillance, immunosuppression management, and shared care between transplant specialists and general clinicians.
ja.ma/4jR6Mrh
ja.ma/4jR6Mrh
October 12, 2026 at 3:30 PM
#JAMAReview: After #HeartTransplant, long-term outcomes depend on rejection surveillance, immunosuppression management, and shared care between transplant specialists and general clinicians.
ja.ma/4jR6Mrh
ja.ma/4jR6Mrh
A new #HeartTransplant urgency score better identified 6-week mortality risk among adult US transplant candidates than the current 6-status system and prioritized sicker candidates without increasing donor-candidate distance.
ja.ma/4jhTxQs
ja.ma/4jhTxQs
October 12, 2026 at 3:15 PM
A new #HeartTransplant urgency score better identified 6-week mortality risk among adult US transplant candidates than the current 6-status system and prioritized sicker candidates without increasing donor-candidate distance.
ja.ma/4jhTxQs
ja.ma/4jhTxQs
🧵 How useful are "pragmatic" clinical trials for informing real-world decision-making?
In the latest JAMA+ Trials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
In the latest JAMA+ Trials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
October 9, 2026 at 8:38 PM
🧵 How useful are "pragmatic" clinical trials for informing real-world decision-making?
In the latest JAMA+ Trials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
In the latest JAMA+ Trials poll, only 10.9% of respondents believed that nearly all trials labeled as "pragmatic" successfully provide useful evidence for real-world decisions.
Among working-age adults in the US, #HeatRelated mortality varied substantially by occupation and industry, with the highest rates in military, farming, fishing and forestry, and construction and extraction occupations.
ja.ma/4edXkKY
ja.ma/4edXkKY
October 9, 2026 at 6:50 PM
Among working-age adults in the US, #HeatRelated mortality varied substantially by occupation and industry, with the highest rates in military, farming, fishing and forestry, and construction and extraction occupations.
ja.ma/4edXkKY
ja.ma/4edXkKY
💬 Editorial: Among older adults with serious illness, both facilitated and self-guided #AdvanceCarePlanning approaches were associated with high rates of advance care planning completion, with no significant differences within Black or White groups.
ja.ma/47Gftxk
ja.ma/47Gftxk
October 9, 2026 at 6:50 PM
💬 Editorial: Among older adults with serious illness, both facilitated and self-guided #AdvanceCarePlanning approaches were associated with high rates of advance care planning completion, with no significant differences within Black or White groups.
ja.ma/47Gftxk
ja.ma/47Gftxk
Among Black and White older adults with serious illness, a facilitated #AdvanceCarePlanning approach did not result in significantly different 1-year advance care planning completion than a self-guided approach within either racial group. ja.ma/3VzXINF
October 9, 2026 at 6:50 PM
Among Black and White older adults with serious illness, a facilitated #AdvanceCarePlanning approach did not result in significantly different 1-year advance care planning completion than a self-guided approach within either racial group. ja.ma/3VzXINF
💬 Editorial: In #ClinicalTrials, extension studies that rely on external controls, simulated comparators, or crossover designs can add useful long-term outcome data, but each approach introduces trade-offs in internal validity and interpretability.
ja.ma/3TJB7O6
ja.ma/3TJB7O6
October 9, 2026 at 6:49 PM
💬 Editorial: In #ClinicalTrials, extension studies that rely on external controls, simulated comparators, or crossover designs can add useful long-term outcome data, but each approach introduces trade-offs in internal validity and interpretability.
ja.ma/3TJB7O6
ja.ma/3TJB7O6
In urban Cienfuegos, Cuba, population control of #Hypertension increased substantially between 2011 and 2023, with improvements in awareness, treatment, and control among treated individuals.
ja.ma/4rR9JKu
ja.ma/4rR9JKu
October 9, 2026 at 6:49 PM
In urban Cienfuegos, Cuba, population control of #Hypertension increased substantially between 2011 and 2023, with improvements in awareness, treatment, and control among treated individuals.
ja.ma/4rR9JKu
ja.ma/4rR9JKu
💬 Editorial: #WomensHealth extends beyond #reproductive #health, #pregnancy, #menopause, and breast and #gynecologic #cancer, and sex differences affect many conditions across medicine. ja.ma/3Wd2fFQ
October 9, 2026 at 6:48 PM
💬 Editorial: #WomensHealth extends beyond #reproductive #health, #pregnancy, #menopause, and breast and #gynecologic #cancer, and sex differences affect many conditions across medicine. ja.ma/3Wd2fFQ
#HealthyDialogue: Approximately 1 in 5 Americans live in rural areas, and upcoming changes under the One Big Beautiful Bill Act may substantially reshape their health care options.
🎙️ Learn more in this episode of Healthy Dialogue: ja.ma/47FAatj
🎙️ Learn more in this episode of Healthy Dialogue: ja.ma/47FAatj
A Healthy Dialogue on Rural Health Care
Rural health care in the US is discussed by JAMA Senior Editor Derek C. Angus, MD, MPH; Mark Holmes, PhD, director of The Cecil G. Sheps Center for Health Services Research at The University of North ...
ja.ma
October 9, 2026 at 6:48 PM
#HealthyDialogue: Approximately 1 in 5 Americans live in rural areas, and upcoming changes under the One Big Beautiful Bill Act may substantially reshape their health care options.
🎙️ Learn more in this episode of Healthy Dialogue: ja.ma/47FAatj
🎙️ Learn more in this episode of Healthy Dialogue: ja.ma/47FAatj
💬 Viewpoint by Emily Packard Dawson, PhD, and Lainie Friedman Ross, MD, PhD: In #Genetics and genomics, germline gene editing raises distinct ethical concerns because intended and unintended edits would extend beyond the treated embryo to future generations. ja.ma/3VSVuJd
October 9, 2026 at 6:47 PM
💬 Viewpoint by Emily Packard Dawson, PhD, and Lainie Friedman Ross, MD, PhD: In #Genetics and genomics, germline gene editing raises distinct ethical concerns because intended and unintended edits would extend beyond the treated embryo to future generations. ja.ma/3VSVuJd
📊 Research Summary: For early #ParkinsonDisease, nicotinamide riboside did not support disease modification, and nonmotor symptom burden worsened more than with placebo.
ja.ma/4yP5e5V
ja.ma/4yP5e5V
October 9, 2026 at 6:47 PM
📊 Research Summary: For early #ParkinsonDisease, nicotinamide riboside did not support disease modification, and nonmotor symptom burden worsened more than with placebo.
ja.ma/4yP5e5V
ja.ma/4yP5e5V
Among patients with early #ParkinsonDisease, treatment with nicotinamide riboside for 52 weeks did not improve clinical outcomes vs placebo and was associated with worse change in overall Movement Disorder Society Unified Parkinson Disease Rating Scale scores. ja.ma/4e4z3af
October 9, 2026 at 6:47 PM
Among patients with early #ParkinsonDisease, treatment with nicotinamide riboside for 52 weeks did not improve clinical outcomes vs placebo and was associated with worse change in overall Movement Disorder Society Unified Parkinson Disease Rating Scale scores. ja.ma/4e4z3af
From 2010 to 2025, US acute care hospital closures exceeded openings, resulting in a net loss of hospitals and hospital beds.
Closure rates were similar in urban and rural areas, while smaller, for-profit, and safety net hospitals closed more often.
ja.ma/4hAuu9X
Closure rates were similar in urban and rural areas, while smaller, for-profit, and safety net hospitals closed more often.
ja.ma/4hAuu9X
October 9, 2026 at 6:46 PM
From 2010 to 2025, US acute care hospital closures exceeded openings, resulting in a net loss of hospitals and hospital beds.
Closure rates were similar in urban and rural areas, while smaller, for-profit, and safety net hospitals closed more often.
ja.ma/4hAuu9X
Closure rates were similar in urban and rural areas, while smaller, for-profit, and safety net hospitals closed more often.
ja.ma/4hAuu9X
#MedNews: Unapproved #GLP-1 drugs such as retatrutide and zenagamtide are being sold on the black market, raising concerns about questionable quality and safety issues.
The Pitfalls of Buying Unapproved GLP-1 Drugs
This Medical News article discusses the reasons behind the burgeoning black market for 2 unapproved GLP-1 weight loss drugs and the potential risks associated with their use.
jamanetwork.com
October 9, 2026 at 3:22 PM
#MedNews: As daily alcohol use declines among younger adults, routine #cannabis use is rising.
What are the risks of more frequent use? Read more:
What are the risks of more frequent use? Read more:
As Drinking Declines, Cannabis Is on the Rise
This Medical News article discusses the increase in routine cannabis use among younger adults, which corresponds with a decrease in regular alcohol use.
jamanetwork.com
October 9, 2026 at 3:21 PM
Jason Alexander, MD, joined JAMA as an Associate Editor in August. Dr Alexander is a clinician educator in the Section of General Internal Medicine at the University of Chicago.
October 9, 2026 at 2:08 PM
Jason Alexander, MD, joined JAMA as an Associate Editor in August. Dr Alexander is a clinician educator in the Section of General Internal Medicine at the University of Chicago.
Jennifer Goldstein MD, MSc, joined JAMA as an Associate Editor on July 1. Dr. Goldstein is an internist and senior physician editor for MCG Health.
October 9, 2026 at 2:05 PM
Jennifer Goldstein MD, MSc, joined JAMA as an Associate Editor on July 1. Dr. Goldstein is an internist and senior physician editor for MCG Health.
Nearly 2 million pediatric concussions occur in the US each year. In the first 24 to 72 hours after a potential head injury, a comprehensive concussion assessment can help identify important signs and symptoms in children and adolescents.
📌 Learn more: ja.ma/4yrjOR3
📌 Learn more: ja.ma/4yrjOR3
October 9, 2026 at 1:00 PM
Nearly 2 million pediatric concussions occur in the US each year. In the first 24 to 72 hours after a potential head injury, a comprehensive concussion assessment can help identify important signs and symptoms in children and adolescents.
📌 Learn more: ja.ma/4yrjOR3
📌 Learn more: ja.ma/4yrjOR3
In this episode of #HealthyDialogue, Wes Ely, MD, MPH, discusses the efforts to define, understand, and hopefully treat long COVID.
#longCOVID
👂 Listen to learn more: ja.ma/4iZBwWX
#longCOVID
👂 Listen to learn more: ja.ma/4iZBwWX
October 8, 2026 at 1:00 PM
In this episode of #HealthyDialogue, Wes Ely, MD, MPH, discusses the efforts to define, understand, and hopefully treat long COVID.
#longCOVID
👂 Listen to learn more: ja.ma/4iZBwWX
#longCOVID
👂 Listen to learn more: ja.ma/4iZBwWX
Among patients with #MASLD, although lean patients had fewer metabolic comorbidities and less severe histologic disease mortality and clinical events did not differ significantly from patients with overweight or #obesity.
#liver #BMI
📌 Learn more: ja.ma/4ysP4ik
#liver #BMI
📌 Learn more: ja.ma/4ysP4ik
October 6, 2026 at 1:00 PM
Among patients with #MASLD, although lean patients had fewer metabolic comorbidities and less severe histologic disease mortality and clinical events did not differ significantly from patients with overweight or #obesity.
#liver #BMI
📌 Learn more: ja.ma/4ysP4ik
#liver #BMI
📌 Learn more: ja.ma/4ysP4ik
For adults with severe #BurnInjury requiring skin grafting, high-dose intravenous #vitaminC did not improve 28-day mortality or persistent organ dysfunction.
📌 Read full article: ja.ma/4hCnmIJ
📌 Read full article: ja.ma/4hCnmIJ
October 3, 2026 at 3:00 PM
For adults with severe #BurnInjury requiring skin grafting, high-dose intravenous #vitaminC did not improve 28-day mortality or persistent organ dysfunction.
📌 Read full article: ja.ma/4hCnmIJ
📌 Read full article: ja.ma/4hCnmIJ
Reposted by JAMA
Postpartum GLP-1 use has increased sharply in the US, finds new USC Schaeffer research in @jama.com.
Among commercially insured patients, nearly 1 in 6 new mothers with type 2 diabetes were prescribed a GLP-1 last year, while prescriptions have risen fastest for obesity and overweight.
Among commercially insured patients, nearly 1 in 6 new mothers with type 2 diabetes were prescribed a GLP-1 last year, while prescriptions have risen fastest for obesity and overweight.
GLP-1 Prescriptions for New Mothers Have Increased Sharply - October 1, 2026 - USC Schaeffer
About 1 in 6 with type 2 diabetes started treatment last year, while prescriptions rose fastest for weight loss. - October 1, 2026
schaeffer.usc.edu
October 1, 2026 at 7:09 PM
Postpartum GLP-1 use has increased sharply in the US, finds new USC Schaeffer research in @jama.com.
Among commercially insured patients, nearly 1 in 6 new mothers with type 2 diabetes were prescribed a GLP-1 last year, while prescriptions have risen fastest for obesity and overweight.
Among commercially insured patients, nearly 1 in 6 new mothers with type 2 diabetes were prescribed a GLP-1 last year, while prescriptions have risen fastest for obesity and overweight.
#MedNews: A ketogenic diet’s liver health benefits outperformed a Mediterranean diet and a low-fat plant-forward diet in a head-to-head trial of people with metabolically unhealthy obesity.
What are the real-world implications?
What are the real-world implications?
Can a Ketogenic Diet Improve Liver Health?
This Medical News article discusses a randomized clinical trial that compared the metabolic effects of 10% weight loss with a Mediterranean diet, a very low-fat, plant-forward diet, and a very low-car...
jamanetwork.com
October 2, 2026 at 3:06 PM
#MedNews: A ketogenic diet’s liver health benefits outperformed a Mediterranean diet and a low-fat plant-forward diet in a head-to-head trial of people with metabolically unhealthy obesity.
What are the real-world implications?
What are the real-world implications?