Meryl Malezieux
@merylneuro.bsky.social
PhD in Neuroscience
Brain-Body interactions / Metabolism & Physiology / Neuroscience
Brain-Body interactions / Metabolism & Physiology / Neuroscience
Pinned
Meryl Malezieux
@merylneuro.bsky.social
· Mar 23
www.biorxiv.org
1/8 New preprint alert!
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
Reposted by Meryl Malezieux
🐟+🐚 =🏠 Shell-dwelling cichlids are true underwater architects, instinctively transforming empty snail shells into protective nests. New research shows: They improve with practice, remember what they learned, and adapt to unusual conditions.
🔗 Press release: www.bi.mpg.de/news/2026-04...
🔗 Press release: www.bi.mpg.de/news/2026-04...
April 10, 2026 at 3:26 PM
🐟+🐚 =🏠 Shell-dwelling cichlids are true underwater architects, instinctively transforming empty snail shells into protective nests. New research shows: They improve with practice, remember what they learned, and adapt to unusual conditions.
🔗 Press release: www.bi.mpg.de/news/2026-04...
🔗 Press release: www.bi.mpg.de/news/2026-04...
Reposted by Meryl Malezieux
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
March 24, 2026 at 12:19 PM
I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.
Reposted by Meryl Malezieux
Exciting new work by @merylneuro.bsky.social et al unpacking how sensory info from the heart impacts the processing of emotions in the brain, focused on one of the most mysterious and fascinating brain regions, Insula.
#GoTeamInsula
www.biorxiv.org/content/10.6...
#GoTeamInsula
www.biorxiv.org/content/10.6...
March 23, 2026 at 7:08 AM
Exciting new work by @merylneuro.bsky.social et al unpacking how sensory info from the heart impacts the processing of emotions in the brain, focused on one of the most mysterious and fascinating brain regions, Insula.
#GoTeamInsula
www.biorxiv.org/content/10.6...
#GoTeamInsula
www.biorxiv.org/content/10.6...
1/8 New preprint alert!
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
www.biorxiv.org
March 23, 2026 at 7:48 AM
1/8 New preprint alert!
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
How are signals from the heart encoded in the brain?
What could be the functional implications of cardioception?
We found that neurons in the posterior insular cortex are precisely tuned to heartbeats, and that this cardio-insular coupling supports emotion coding in mice.
Reposted by Meryl Malezieux
1/8. New preprint!
Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠.
Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone.
www.biorxiv.org/content/10.6...
Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠.
Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone.
www.biorxiv.org/content/10.6...
March 16, 2026 at 11:05 AM
1/8. New preprint!
Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠.
Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone.
www.biorxiv.org/content/10.6...
Using fUSi in head-fixed mice🐭, we found that arousal events trigger a brain-wide wave of activity 🌊🧠.
Surprisingly, this pattern was preserved during opto manipulations of the locus coeruleus, pointing to a minor role for noradrenergic tone.
www.biorxiv.org/content/10.6...
Reposted by Meryl Malezieux
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
September 11, 2025 at 8:14 PM
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
Reposted by Meryl Malezieux
Are interoception and mental health linked? Many assume so, with interoception even described as a psychiatric “p-factor.” But in our latest preprint, we were surprised to find little evidence for such a connection. www.medrxiv.org/content/10.1... 🧵 Thread with our reflections on the matter 👇
Interoceptive Ability is Unrelated to Mental Health Symptoms: Evidence From a Large Scale Multi-Domain Psychophysical Investigation
Interoception-the sensing and perception of the internal viscera-is widely cast as a transdiagnostic mechanism linking brain-body interaction to mental illness. Prevailing models propose that altered ...
www.medrxiv.org
August 27, 2025 at 4:17 PM
Are interoception and mental health linked? Many assume so, with interoception even described as a psychiatric “p-factor.” But in our latest preprint, we were surprised to find little evidence for such a connection. www.medrxiv.org/content/10.1... 🧵 Thread with our reflections on the matter 👇
Reposted by Meryl Malezieux
📣 We are expanding! Repost 🙏🏽
- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)
www.neuroact.in
- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)
www.neuroact.in
August 1, 2025 at 12:22 PM
📣 We are expanding! Repost 🙏🏽
- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)
www.neuroact.in
- Postdoc (funded by @simonsfoundation.org grant on synchronisation between cognitive representations and stepping)
- Project Associates
- Create your role! (Reach out if you are keen on these topics and these roles do not define you 👀🤗)
www.neuroact.in
Reposted by Meryl Malezieux
A cross-species study captured an emotional brain state characterized by lingering brain activity in higher-order areas. “It’s one of those moments where you’re getting a first glimpse at a vast and complex landscape,” says @deisseroth.bsky.social.
By @callimcflurry.bsky.social
bit.ly/3U33raF
By @callimcflurry.bsky.social
bit.ly/3U33raF
Eye puffs prompt separable sensory, affective brain responses in mice, people
Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.
bit.ly
July 29, 2025 at 2:13 PM
A cross-species study captured an emotional brain state characterized by lingering brain activity in higher-order areas. “It’s one of those moments where you’re getting a first glimpse at a vast and complex landscape,” says @deisseroth.bsky.social.
By @callimcflurry.bsky.social
bit.ly/3U33raF
By @callimcflurry.bsky.social
bit.ly/3U33raF
Reposted by Meryl Malezieux
🧠 Registration is open for the Bordeaux Neurocampus Conference on Brain–Body Interactions!
📍 Bordeaux, Oct 1–3, 2025
🗓️ Submit abstracts by July 1
🔗 brainconf.u-bordeaux.fr/en/
@mariocarta.bsky.social, @francoisgeorges.bsky.social, @cglangetas.bsky.social, E. Montalban @agnesnadjar.bsky.social.
📍 Bordeaux, Oct 1–3, 2025
🗓️ Submit abstracts by July 1
🔗 brainconf.u-bordeaux.fr/en/
@mariocarta.bsky.social, @francoisgeorges.bsky.social, @cglangetas.bsky.social, E. Montalban @agnesnadjar.bsky.social.
May 9, 2025 at 11:28 AM
🧠 Registration is open for the Bordeaux Neurocampus Conference on Brain–Body Interactions!
📍 Bordeaux, Oct 1–3, 2025
🗓️ Submit abstracts by July 1
🔗 brainconf.u-bordeaux.fr/en/
@mariocarta.bsky.social, @francoisgeorges.bsky.social, @cglangetas.bsky.social, E. Montalban @agnesnadjar.bsky.social.
📍 Bordeaux, Oct 1–3, 2025
🗓️ Submit abstracts by July 1
🔗 brainconf.u-bordeaux.fr/en/
@mariocarta.bsky.social, @francoisgeorges.bsky.social, @cglangetas.bsky.social, E. Montalban @agnesnadjar.bsky.social.
If you're attending #NeuroFrance2025 in beautiful Montpellier and you're interested in sensory processing and emotions, don't miss out our symposium tomorrow (Thursday) morning! Organized together with @mariocarta.bsky.social
@socneuro.bsky.social
@socneuro.bsky.social
May 14, 2025 at 1:14 PM
If you're attending #NeuroFrance2025 in beautiful Montpellier and you're interested in sensory processing and emotions, don't miss out our symposium tomorrow (Thursday) morning! Organized together with @mariocarta.bsky.social
@socneuro.bsky.social
@socneuro.bsky.social
Next up in the Interoception conferences: BrainBody conference in Bordeaux in October! Can't wait for this one
📣 Registrations and abstract submissions for our international conference BrainBody have just opened!
📅 1-3 October 2025
📍 Bordeaux, France
📝Abstract submission and early bird registration deadline: July 1st!
brainconf.u-bordeaux.fr/en/
📅 1-3 October 2025
📍 Bordeaux, France
📝Abstract submission and early bird registration deadline: July 1st!
brainconf.u-bordeaux.fr/en/
April 29, 2025 at 9:44 AM
Next up in the Interoception conferences: BrainBody conference in Bordeaux in October! Can't wait for this one
Had such great fun at the Inaugural Interoception Keystone Symposia at the Allen Institute! Feeling grateful and inspired after all these talks and rich discussions, what an amazing time @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Interoception: Neural Sensing and Control of Organ Function | Keystone Symposia
Join us at the Keystone Symposia on Interoception: Neural Sensing and Control of Organ Function, April 2025, in Seattle, with field leaders!
www.keystonesymposia.org
April 25, 2025 at 3:01 AM
Had such great fun at the Inaugural Interoception Keystone Symposia at the Allen Institute! Feeling grateful and inspired after all these talks and rich discussions, what an amazing time @keystonesymposia.bsky.social
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Reposted by Meryl Malezieux
Thanks @alexkwan.bsky.social! It was quite an effort indeed 😅 But I hope it'll be valuable for many labs studying effects of Psi on mouse behavior.
A much-needed joint effort from five labs to see which behavioral effects of psilocybin in mice are reliable, and which may be spurious 🐁🍄
@theborislab.bsky.social @mazenkheirbek.bsky.social @indigenerd.bsky.social Vikaas Sohal and Stephan Lammel 👏
www.biorxiv.org/content/10.1...
@theborislab.bsky.social @mazenkheirbek.bsky.social @indigenerd.bsky.social Vikaas Sohal and Stephan Lammel 👏
www.biorxiv.org/content/10.1...
A multi-institutional investigation of psilocybin's effects on mouse behavior
Studies reporting novel therapeutic effects of psychedelic drugs are rapidly emerging. However, the reproducibility and reliability of these findings could remain uncertain for years. Here, we impleme...
www.biorxiv.org
April 9, 2025 at 8:18 PM
Thanks @alexkwan.bsky.social! It was quite an effort indeed 😅 But I hope it'll be valuable for many labs studying effects of Psi on mouse behavior.
Reposted by Meryl Malezieux
New paper alert—this is a master class on interdisciplinary collaboration updating the basic understanding and clinical outlook for neurocardiology. Led by Olu Ajijola Kalyanam Shivkumar and a cardiology dream team. #interoception
physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Clinical neurocardiology: defining the value of neuroscience‐based cardiovascular therapeutics – 2024 update
Abstract figure legend Clinical neurocardiology: pathophysiology, diagnostics and therapeutics. Illustrated is a summary of bidirectional interactions between the heart and nervous system, with a pat...
physoc.onlinelibrary.wiley.com
March 14, 2025 at 11:52 PM
New paper alert—this is a master class on interdisciplinary collaboration updating the basic understanding and clinical outlook for neurocardiology. Led by Olu Ajijola Kalyanam Shivkumar and a cardiology dream team. #interoception
physoc.onlinelibrary.wiley.com/doi/10.1113/...
physoc.onlinelibrary.wiley.com/doi/10.1113/...