Exploring Aging & Longevity with Machine Learning 🔍 | Unraveling Life's Code | C.elegans | Consultant
The study uncovers neuron-specific aging patterns and points to potential neuroprotective interventions.
Congratulations! 🎉
www.nature.com/articles/s43...
The study uncovers neuron-specific aging patterns and points to potential neuroprotective interventions.
Congratulations! 🎉
www.nature.com/articles/s43...
The article explores how organelle #proteostasis preserves cellular function, and how its decline contributes to #aging and disease.
febs.onlinelibrary.wiley.com/doi/10.1111/...
The article explores how organelle #proteostasis preserves cellular function, and how its decline contributes to #aging and disease.
febs.onlinelibrary.wiley.com/doi/10.1111/...
New work from our #CRC1678 members @bjornschumacher.bsky.social and @meyerdh.bsky.social reveals why some neurons age faster. Using neuron‑specific aging clocks, they identified vulnerable neurons and highlight syringic acid and vanoxerine as promising neuroprotective hits.🧬
We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability.
🧪
www.nature.com/articles/s43...
#Neurodegeneration 🧵👇 (1/n)
New work from our #CRC1678 members @bjornschumacher.bsky.social and @meyerdh.bsky.social reveals why some neurons age faster. Using neuron‑specific aging clocks, they identified vulnerable neurons and highlight syringic acid and vanoxerine as promising neuroprotective hits.🧬
We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability.
🧪
www.nature.com/articles/s43...
#Neurodegeneration 🧵👇 (1/n)
We used transcriptomic aging clocks for single-neuron-types in C. elegans and found neuron-specific biological age predicts vulnerability.
🧪
www.nature.com/articles/s43...
#Neurodegeneration 🧵👇 (1/n)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
link.springer.com/article/10.1...
@leibnizfli.bsky.social @uniofeastanglia.bsky.social
link.springer.com/article/10.1...
@leibnizfli.bsky.social @uniofeastanglia.bsky.social
Why do males and females so often age and die at different rates?
We argue that sex-specific mutation accumulation may be the most parsimonious evolutionary explanation for sex-biased ageing:
ecoevorxiv.org/repository/v...
Why do males and females so often age and die at different rates?
We argue that sex-specific mutation accumulation may be the most parsimonious evolutionary explanation for sex-biased ageing:
ecoevorxiv.org/repository/v...
www.nature.com/articles/s41...
🧵
www.nature.com/articles/s41...
🧵
#AgingResearch #Longevity
onlinelibrary.wiley.com/doi/10.1111/...
#AgingResearch #Longevity
⭐ David Meyer @meyerdh.bsky.social, PhD Paper Award
⭐ Michael Skinnider @skinnider.bsky.social Early Career Award
⭐ scverse @scverse.bsky.social, Innovative Resource Award, accepted by Ilan Gold
Watch their award ceremony talks👇& congrats to all!
⭐ David Meyer @meyerdh.bsky.social, PhD Paper Award
⭐ Michael Skinnider @skinnider.bsky.social Early Career Award
⭐ scverse @scverse.bsky.social, Innovative Resource Award, accepted by Ilan Gold
Watch their award ceremony talks👇& congrats to all!
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Can Chen for “Structure-Aware Protein Self-Supervised Learning” doi.org/10.1093/bioi...
Yifan Zhao for “Learning interpretable cellular and gene signature embeddings from single-cell transcriptomic data” doi.org/10.1038/s414...
#bc2basel
Massive thanks to (Hanna!) @kokkonut.bsky.social, Margaux Bieuville, Victor Ronget, and the fantastic people at The Gutenberg Workshops in the Life Sciences
Massive thanks to (Hanna!) @kokkonut.bsky.social, Margaux Bieuville, Victor Ronget, and the fantastic people at The Gutenberg Workshops in the Life Sciences
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s41...
Congratulations to the Langer lab @mpiage.bsky.social, Amir, and the rest of the team!
www.nature.com/articles/s43...
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Thank you for your guidance and inspiration @bjornschumacher.bsky.social
#SIBAwards #bc2basel #Bioinformatics
“David Meyer’s paper ‘Aging clocks based on accumulating stochastic variation’ presents a completely novel concept and a fresh way to address the problem”.
#Bioinformatics #SIBawards #bc2basel
Thank you for your guidance and inspiration @bjornschumacher.bsky.social
#SIBAwards #bc2basel #Bioinformatics
“David Meyer’s paper ‘Aging clocks based on accumulating stochastic variation’ presents a completely novel concept and a fresh way to address the problem”.
#Bioinformatics #SIBawards #bc2basel
Thank you for your guidance and inspiration @bjornschumacher.bsky.social
#SIBAwards #bc2basel #Bioinformatics