Horst Obenhaus
@octoscience.bsky.social
PostDoc at the Kavli Institute for Systems Neuroscience at NTNU Trondheim. Whitman Scientist at the Marine Biological Laboratory (MBL) in Woods Hole, MA. I am studying sleep in octopuses and cuttlefish. 🐙
Reposted by Horst Obenhaus
Masa's paper is out in Hippocampus. The left-right alternation of hippocampal theta sequences at T-maze choice points, much loved as a 'planning' signal, falls straight out of MEC dynamics. Well done @masahironakano.bsky.social, fun project with @clopathlab.bsky.social
doi.org/10.1002/hipo.70131
doi.org/10.1002/hipo.70131
September 19, 2026 at 9:59 AM
Masa's paper is out in Hippocampus. The left-right alternation of hippocampal theta sequences at T-maze choice points, much loved as a 'planning' signal, falls straight out of MEC dynamics. Well done @masahironakano.bsky.social, fun project with @clopathlab.bsky.social
doi.org/10.1002/hipo.70131
doi.org/10.1002/hipo.70131
Reposted by Horst Obenhaus
🤹 How can you now use this new knowledge?
Together with the ReScale4DL user-friendly framework, we provide systematic guidelines for selecting an image resolution that balances accuracy, throughput, and cost.
Together with the ReScale4DL user-friendly framework, we provide systematic guidelines for selecting an image resolution that balances accuracy, throughput, and cost.
September 18, 2026 at 5:18 PM
🤹 How can you now use this new knowledge?
Together with the ReScale4DL user-friendly framework, we provide systematic guidelines for selecting an image resolution that balances accuracy, throughput, and cost.
Together with the ReScale4DL user-friendly framework, we provide systematic guidelines for selecting an image resolution that balances accuracy, throughput, and cost.
Reposted by Horst Obenhaus
This is just astonishingly cute.
Oh to be a little Tardigrade walking around a microscopic volvox algae colony. 🫧🐻🧪
September 19, 2026 at 12:20 AM
This is just astonishingly cute.
Reposted by Horst Obenhaus
Hi friends & colleagues! I’m on the hunt for a tenure-track home! I’m a BRAIN Initiative K99/R00 scholar studying learning & memory at the intersection of experimental neuroscience, theory, & machine learning/AI. I’d love to connect & would appreciate help spreading the word! web.mit.edu/hsw/www/
September 15, 2026 at 8:11 PM
Hi friends & colleagues! I’m on the hunt for a tenure-track home! I’m a BRAIN Initiative K99/R00 scholar studying learning & memory at the intersection of experimental neuroscience, theory, & machine learning/AI. I’d love to connect & would appreciate help spreading the word! web.mit.edu/hsw/www/
Reposted by Horst Obenhaus
Are virtual flies playing Beat Saber? SM64? Doom? No.
The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown:
www.neuroai.science/p/are-flies-...
The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown:
www.neuroai.science/p/are-flies-...
Are flies playing Beat Saber?
What a time to be alive!
www.neuroai.science
September 14, 2026 at 3:21 PM
Are virtual flies playing Beat Saber? SM64? Doom? No.
The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown:
www.neuroai.science/p/are-flies-...
The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown:
www.neuroai.science/p/are-flies-...
Reposted by Horst Obenhaus
it turned out to be an incredible school, a masterclass in pedagogy, organization and (research) software developing.
so glad I heard about the Prague edition in time, will be pointing people to it in random contexts #aspp2026
so glad I heard about the Prague edition in time, will be pointing people to it in random contexts #aspp2026
You are in science and write Python every day? But you feel you want to understand the Python part a little bit better? Then join us in Prague, Czechia for this year’s summer school ‘Advanced Scientific Programming in Python’. 🧑🔬🧑💻🧑🏫 30st August–06th September 2026. #aspp2026
Apply now: aspp.school
Apply now: aspp.school
September 7, 2026 at 11:08 AM
it turned out to be an incredible school, a masterclass in pedagogy, organization and (research) software developing.
so glad I heard about the Prague edition in time, will be pointing people to it in random contexts #aspp2026
so glad I heard about the Prague edition in time, will be pointing people to it in random contexts #aspp2026
Reposted by Horst Obenhaus
🚨🚨🚨 napari 0.9.0 is out! 🚨🚨🚨
This is a huge release for us and for our community, with over 30 people contributing new features, improvements, and bug fixes in the 6 weeks since 0.8.0! Release notes here:
napari.org/stable/relea...
and some highlights in the thread below! 👇
This is a huge release for us and for our community, with over 30 people contributing new features, improvements, and bug fixes in the 6 weeks since 0.8.0! Release notes here:
napari.org/stable/relea...
and some highlights in the thread below! 👇
napari 0.9.0
Tue, Aug 25, 2026 We’re happy to announce the release of napari 0.9.0! napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing l...
napari.org
August 26, 2026 at 10:39 AM
🚨🚨🚨 napari 0.9.0 is out! 🚨🚨🚨
This is a huge release for us and for our community, with over 30 people contributing new features, improvements, and bug fixes in the 6 weeks since 0.8.0! Release notes here:
napari.org/stable/relea...
and some highlights in the thread below! 👇
This is a huge release for us and for our community, with over 30 people contributing new features, improvements, and bug fixes in the 6 weeks since 0.8.0! Release notes here:
napari.org/stable/relea...
and some highlights in the thread below! 👇
Reposted by Horst Obenhaus
Pharmacobehavioral space of MoSeq syllables significantly overlaps with scalar locomotion features https://www.biorxiv.org/content/10.64898/2026.08.12.744023v1
August 17, 2026 at 5:45 PM
Pharmacobehavioral space of MoSeq syllables significantly overlaps with scalar locomotion features https://www.biorxiv.org/content/10.64898/2026.08.12.744023v1
Reposted by Horst Obenhaus
light-activated tetanus neurotoxin (LATeNT) by the @aliceyting.bsky.social lab. Includes a comparison with the light-switchable PdCO (www.nature.com/articles/s41...), showing a long lasting inhibition for 1h hour post illumination.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Light-activated tetanus neurotoxin for conditional proteolysis and inducible synaptic inhibition in vivo - Nature Methods
LATeNT is a light-activatable form of tetanus neurotoxin that can be used for spatiotemporally precise inhibition of exocytosis in neurons and other cells. It can inhibit synaptic transmission in vivo...
www.nature.com
August 3, 2026 at 6:48 AM
light-activated tetanus neurotoxin (LATeNT) by the @aliceyting.bsky.social lab. Includes a comparison with the light-switchable PdCO (www.nature.com/articles/s41...), showing a long lasting inhibition for 1h hour post illumination.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Horst Obenhaus
Nordic Neuroscience Meeting 2027 in Iceland!
June 14-16, 2027
Call for symposia, see details below
June 14-16, 2027
Call for symposia, see details below
July 2, 2026 at 10:38 AM
Nordic Neuroscience Meeting 2027 in Iceland!
June 14-16, 2027
Call for symposia, see details below
June 14-16, 2027
Call for symposia, see details below
Reposted by Horst Obenhaus
High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations https://www.biorxiv.org/content/10.64898/2026.07.28.741086v1
July 30, 2026 at 4:16 PM
High Axial Resolution Is Necessary for Quantitative Two-Photon Calcium Imaging of Neuronal Populations https://www.biorxiv.org/content/10.64898/2026.07.28.741086v1
Reposted by Horst Obenhaus
📣New paper!
How does the sleeping brain help us to integrate new experiences while managing memories from the past?
For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n
www.nature.com/articles/s41...
🧪🧠📈👩🔬#OpenAccess
How does the sleeping brain help us to integrate new experiences while managing memories from the past?
For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n
www.nature.com/articles/s41...
🧪🧠📈👩🔬#OpenAccess
Experience reorganizes content-specific memory traces in macaques - Nature Neuroscience
In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep and can sometim...
www.nature.com
July 30, 2026 at 12:01 PM
📣New paper!
How does the sleeping brain help us to integrate new experiences while managing memories from the past?
For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n
www.nature.com/articles/s41...
🧪🧠📈👩🔬#OpenAccess
How does the sleeping brain help us to integrate new experiences while managing memories from the past?
For his PhD work, @sabbaspoor.bsky.social recorded hippocampal ensembles in freely moving monkeys and found something unexpected. 🧵1/n
www.nature.com/articles/s41...
🧪🧠📈👩🔬#OpenAccess
In honor of Ed Kravitz, with support from the Grass Foundation @grassfoundation.bsky.social, this scholarship supports students attending research training courses at the MBL. The Grass Foundation will match your contribution. internationalsocietyofneuroethology.growthzoneapp.com/ap/contribut...
Former ICN president Paul Katz introduces the Edward Kravitz Memorial Scholarship which is meant to support researchers attending summer courses @mblscience.bsky.social in Woods Hole.
July 28, 2026 at 1:35 PM
In honor of Ed Kravitz, with support from the Grass Foundation @grassfoundation.bsky.social, this scholarship supports students attending research training courses at the MBL. The Grass Foundation will match your contribution. internationalsocietyofneuroethology.growthzoneapp.com/ap/contribut...
Reposted by Horst Obenhaus
Check out this compact 920 nm ultrafast fs laser for 2p imaging of GCaMP, etc.. Mounted on its side like this, it takes up very little space on the table.
That's the Axon 920, generously loaned to the course thanks to @ewadorotaz.bsky.social and others at Coherent. It's what we use on our own rigs.
That's the Axon 920, generously loaned to the course thanks to @ewadorotaz.bsky.social and others at Coherent. It's what we use on our own rigs.
July 27, 2026 at 7:39 PM
Check out this compact 920 nm ultrafast fs laser for 2p imaging of GCaMP, etc.. Mounted on its side like this, it takes up very little space on the table.
That's the Axon 920, generously loaned to the course thanks to @ewadorotaz.bsky.social and others at Coherent. It's what we use on our own rigs.
That's the Axon 920, generously loaned to the course thanks to @ewadorotaz.bsky.social and others at Coherent. It's what we use on our own rigs.
Reposted by Horst Obenhaus
This looks pretty fantastic. Master's level - transitioning into PhD. The headline got me "Imagine building 3D microscopes right by the beach!"
Research Fellowship in Bioimaging at the Quantitative BioImaging Lab (QBI), CCMAR Algarve, Portugal, IMAGINE project
ccmar.ualg.pt/en/job/ccmar...
Research Fellowship in Bioimaging at the Quantitative BioImaging Lab (QBI), CCMAR Algarve, Portugal, IMAGINE project
ccmar.ualg.pt/en/job/ccmar...
CCMAR/BINCGAM/10/2026 | Research Fellowship | Bioimaging | 1 Vacancy
Research Fellowship – 1 VacancyWithin the project - IMAGINEProject Refº: HORIZON-INFRA-2022-TECH-01-101094250Ref.
ccmar.ualg.pt
July 21, 2026 at 2:09 PM
This looks pretty fantastic. Master's level - transitioning into PhD. The headline got me "Imagine building 3D microscopes right by the beach!"
Research Fellowship in Bioimaging at the Quantitative BioImaging Lab (QBI), CCMAR Algarve, Portugal, IMAGINE project
ccmar.ualg.pt/en/job/ccmar...
Research Fellowship in Bioimaging at the Quantitative BioImaging Lab (QBI), CCMAR Algarve, Portugal, IMAGINE project
ccmar.ualg.pt/en/job/ccmar...
Reposted by Horst Obenhaus
I’m excited to share our latest preprint, and the main work from my PhD, on the role of the direct entorhinal input in hippocampus CA1 spatial coding.
1/9
1/9
The emergence of a novel CA1 spatial map requires direct entorhinal input https://www.biorxiv.org/content/10.64898/2026.07.02.736055v1
July 9, 2026 at 9:30 AM
I’m excited to share our latest preprint, and the main work from my PhD, on the role of the direct entorhinal input in hippocampus CA1 spatial coding.
1/9
1/9
Reposted by Horst Obenhaus
During sleep, neurons in the hippocampus 'replay' past activity patterns. This is thought to underlie memory consolidation 🧠
After a busy day, how does the brain sort out what is worth replaying? 🤔
Check out this preprint 📃 from Tirole, Duvelle and Bendor for answers! doi.org/10.64898/202...
After a busy day, how does the brain sort out what is worth replaying? 🤔
Check out this preprint 📃 from Tirole, Duvelle and Bendor for answers! doi.org/10.64898/202...
Time, but not reward, shapes replay-based episodic prioritization
Why are some experiences remembered better than others? Leading theories propose that hippocampal replay prioritizes memories for consolidation according to their expected future value. We recorded hi...
doi.org
July 2, 2026 at 3:42 PM
During sleep, neurons in the hippocampus 'replay' past activity patterns. This is thought to underlie memory consolidation 🧠
After a busy day, how does the brain sort out what is worth replaying? 🤔
Check out this preprint 📃 from Tirole, Duvelle and Bendor for answers! doi.org/10.64898/202...
After a busy day, how does the brain sort out what is worth replaying? 🤔
Check out this preprint 📃 from Tirole, Duvelle and Bendor for answers! doi.org/10.64898/202...
🌟 NEW OCTRON RELEASE! 🌟
Want to track your animals using the command line? You can now train models and predict videos with single prompts in a terminal! Ideal for batch jobs, headless servers, and remote machines.
Big shout-out to @roald-arboel.com for helping with this release!
Want to track your animals using the command line? You can now train models and predict videos with single prompts in a terminal! Ideal for batch jobs, headless servers, and remote machines.
Big shout-out to @roald-arboel.com for helping with this release!
June 29, 2026 at 9:40 PM
🌟 NEW OCTRON RELEASE! 🌟
Want to track your animals using the command line? You can now train models and predict videos with single prompts in a terminal! Ideal for batch jobs, headless servers, and remote machines.
Big shout-out to @roald-arboel.com for helping with this release!
Want to track your animals using the command line? You can now train models and predict videos with single prompts in a terminal! Ideal for batch jobs, headless servers, and remote machines.
Big shout-out to @roald-arboel.com for helping with this release!
Reposted by Horst Obenhaus
Representational drift - the change in cells' responses to the same stimulus over time - may be a feature rather than a bug.
Thank you to @dianakwon.bsky.social for giving me a chance to talk about this fascinating topic. 🤯 The brain never ceases to amaze!
Thank you to @dianakwon.bsky.social for giving me a chance to talk about this fascinating topic. 🤯 The brain never ceases to amaze!
My latest feature for @nature.com is about "representational drift," a concept that's turned some long-standing ideas of how the brain works on its head.
“When people talk about this phenomenon, it’s exciting because it’s just so full of possibilities." - Andrew Fink
“When people talk about this phenomenon, it’s exciting because it’s just so full of possibilities." - Andrew Fink
The brain’s code seems to be in constant flux. Neuroscientists are baffled
Neurons fire much more erratically than researchers thought. What does that mean for how the brain works?
www.nature.com
June 5, 2026 at 2:49 PM
Representational drift - the change in cells' responses to the same stimulus over time - may be a feature rather than a bug.
Thank you to @dianakwon.bsky.social for giving me a chance to talk about this fascinating topic. 🤯 The brain never ceases to amaze!
Thank you to @dianakwon.bsky.social for giving me a chance to talk about this fascinating topic. 🤯 The brain never ceases to amaze!
Reposted by Horst Obenhaus
A hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence
www.thetransmitter.org/reproducibil...
www.thetransmitter.org/reproducibil...
18 teams analyzed a neuro dataset and got different answers
Disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.
www.thetransmitter.org
June 1, 2026 at 2:38 PM
A hackathon reveals that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data, write @mattiachini.bsky.social and Gaelle Chapuis. #neuroskyence
www.thetransmitter.org/reproducibil...
www.thetransmitter.org/reproducibil...
Reposted by Horst Obenhaus
Ultrasensitive voltage imaging reveals distinct electrical microdomains in neurons https://www.biorxiv.org/content/10.64898/2026.05.27.728040v1
May 31, 2026 at 7:15 AM
Ultrasensitive voltage imaging reveals distinct electrical microdomains in neurons https://www.biorxiv.org/content/10.64898/2026.05.27.728040v1
Reposted by Horst Obenhaus
What is the minimal machinery needed for complex, cognition-like behavior? With @lostintheswarm.bsky.social, we show how self-sustained calcium oscillations, diffusion, and mechanics may be enough to coordinate behavior across a single cell with no nervous system.
www.biorxiv.org/content/10.6...
1/
www.biorxiv.org/content/10.6...
1/
May 19, 2026 at 9:18 PM
What is the minimal machinery needed for complex, cognition-like behavior? With @lostintheswarm.bsky.social, we show how self-sustained calcium oscillations, diffusion, and mechanics may be enough to coordinate behavior across a single cell with no nervous system.
www.biorxiv.org/content/10.6...
1/
www.biorxiv.org/content/10.6...
1/
Reposted by Horst Obenhaus
Our NeuroAI study made it onto the cover of Nature Machine Intelligence ❤️.
In it, we demonstrate that a developmentally-inspired visual diet can drastically improve the robustness of ANN-based vision systems.
www.nature.com/articles/s42...
open access, open code, open weights, open science.
In it, we demonstrate that a developmentally-inspired visual diet can drastically improve the robustness of ANN-based vision systems.
www.nature.com/articles/s42...
open access, open code, open weights, open science.
May 26, 2026 at 2:22 PM
Our NeuroAI study made it onto the cover of Nature Machine Intelligence ❤️.
In it, we demonstrate that a developmentally-inspired visual diet can drastically improve the robustness of ANN-based vision systems.
www.nature.com/articles/s42...
open access, open code, open weights, open science.
In it, we demonstrate that a developmentally-inspired visual diet can drastically improve the robustness of ANN-based vision systems.
www.nature.com/articles/s42...
open access, open code, open weights, open science.