Elias Spiliotis
@septinlab.bsky.social
Professor of Cell Biology (University of Virginia), Research Scientist. Science, music, sports and politics. Opinions are my own and not of my lab or university.
Pinned
Elias Spiliotis
@septinlab.bsky.social
· Jan 21
a woman in a suit and tie has the words wait what written on her face
ALT: a woman in a suit and tie has the words wait what written on her face
media.tenor.com
Two new 🔥pre-prints 🔥 TODAY by us & @pwoakes.bsky.social @myosincity.bsky.social
change the way we think about the septin cytoskeleton
Septins buffer mechanical stress on actin and membranes!
Septins are like intermediate filaments
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
change the way we think about the septin cytoskeleton
Septins buffer mechanical stress on actin and membranes!
Septins are like intermediate filaments
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
September is for Septins!
#SeptforSeptins
Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins
Still accepting papers @ascbiology.bsky.social
www.molbiolcell.org/cell-biology...
#SeptforSeptins
Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins
Still accepting papers @ascbiology.bsky.social
www.molbiolcell.org/cell-biology...
Molecular Biology of the Cell (MBoC)
www.molbiolcell.org
September 15, 2026 at 11:15 AM
September is for Septins!
#SeptforSeptins
Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins
Still accepting papers @ascbiology.bsky.social
www.molbiolcell.org/cell-biology...
#SeptforSeptins
Time for septin spice lattes... and submitting your septin paper to the MBoC Special Issue: Cell Biology of Septins
Still accepting papers @ascbiology.bsky.social
www.molbiolcell.org/cell-biology...
We're launching a search for two open-rank positions with preference for Assistant/Associate Professors in the Department of Cell Biology at University of Virginia.
If you're a card-carrying cell biologist, consider applying here now:
apply.interfolio.com/191024
If you're a card-carrying cell biologist, consider applying here now:
apply.interfolio.com/191024
Bill Belichick Looking For A New Job Meme
ALT: Bill Belichick Looking For A New Job Meme
static.klipy.com
August 26, 2026 at 8:13 PM
We're launching a search for two open-rank positions with preference for Assistant/Associate Professors in the Department of Cell Biology at University of Virginia.
If you're a card-carrying cell biologist, consider applying here now:
apply.interfolio.com/191024
If you're a card-carrying cell biologist, consider applying here now:
apply.interfolio.com/191024
That’s the most psychedelic science poster I have ever seen - let alone be part of. Inspired to raise my game.
Final call for early registration! 📢 The 2026 Triangle Cytoskeleton Meeting is coming up on September 21st.
🧬 Early Registration ($80): Ends Aug 24th
🧬 Late Registration ($100): Ends Sept 14th
Sign up now to lock in your spot. Visit our website for more info trianglecytoskeleton.com
🧬 Early Registration ($80): Ends Aug 24th
🧬 Late Registration ($100): Ends Sept 14th
Sign up now to lock in your spot. Visit our website for more info trianglecytoskeleton.com
August 21, 2026 at 8:10 PM
That’s the most psychedelic science poster I have ever seen - let alone be part of. Inspired to raise my game.
Reposted by Elias Spiliotis
Spotlight: @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) describe the role of PAK4 in vertex remodeling, thereby maintaining epithelial integrity and barrier function. @raghavan-thiaga.bsky.social and @kuba-sedzinski.bsky.social discuss the study: rupress.org/jcb/article/...
August 17, 2026 at 6:00 PM
Spotlight: @babliadhikary.bsky.social et al. (rupress.org/jcb/article/...) describe the role of PAK4 in vertex remodeling, thereby maintaining epithelial integrity and barrier function. @raghavan-thiaga.bsky.social and @kuba-sedzinski.bsky.social discuss the study: rupress.org/jcb/article/...
Reposted by Elias Spiliotis
Ok, we know nothing about the brain "More than 80% of eliminated dendritic spines reappeared at their original locations after recovery [from hibernation]": www.science.org/doi/10.1126/...
Artificial hibernation reveals synaptic engram architecture associated with memory retention
Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal represen...
www.science.org
August 18, 2026 at 5:29 AM
Ok, we know nothing about the brain "More than 80% of eliminated dendritic spines reappeared at their original locations after recovery [from hibernation]": www.science.org/doi/10.1126/...
Reposted by Elias Spiliotis
New NSF BIO solicitation is live.... this replaces the previous IOS, MCB, DEB solicitation
www.nsf.gov/funding/oppo...
www.nsf.gov/funding/oppo...
August 17, 2026 at 3:43 PM
New NSF BIO solicitation is live.... this replaces the previous IOS, MCB, DEB solicitation
www.nsf.gov/funding/oppo...
www.nsf.gov/funding/oppo...
Reposted by Elias Spiliotis
“Scientists should stop trying to be neutral and instead embrace their values,”says a group of top climate scientists, including @katharinehayhoe.com. The neutrality myth is harming the reputation of science right when we need it most.” #ClimateCrisis
Science isn’t neutral. It’s science.
Science isn’t neutral. It’s science.
Prominent climate scientist argues it's time to ditch the 'myth of neutrality' | CBC Radio
Climate scientist Katharine Hayhoe talks to Bob McDonald about the polarization of science and why she thinks scientists should stop pretending to be neutral when it's our planet at risk.
www.cbc.ca
August 15, 2026 at 4:16 AM
“Scientists should stop trying to be neutral and instead embrace their values,”says a group of top climate scientists, including @katharinehayhoe.com. The neutrality myth is harming the reputation of science right when we need it most.” #ClimateCrisis
Science isn’t neutral. It’s science.
Science isn’t neutral. It’s science.
Innovation: Investigators innovate by modifying standard techniques to fit new contexts, overcome resource limits, or address unique constraints. This adaptive approach involves customizing tools or blending distinct research traditions…
August 15, 2026 at 4:54 AM
Innovation: Investigators innovate by modifying standard techniques to fit new contexts, overcome resource limits, or address unique constraints. This adaptive approach involves customizing tools or blending distinct research traditions…
Hope to run into this fellow Charlottesvillian at some point and bow in appreciation. He strips down the nonsense like no other.
Normally I just appreciatively read @jamellebouie.net 's columns-sharable video content just isn't my bag. But this is a very, very, very trenchant piece of commentary that captures a lot of how I increasingly understand the disjunction between the commentary environment and on-the-ground politics.
The pundits have completely lost the plot
YouTube video by Takes™ by Jamelle Bouie
www.youtube.com
August 13, 2026 at 7:33 PM
Hope to run into this fellow Charlottesvillian at some point and bow in appreciation. He strips down the nonsense like no other.
Reposted by Elias Spiliotis
It was an honor to write this remembrance of Susumu Tonegawa (1939–2026) -- a scientist whose discoveries transformed biology and whose lab shaped generations of neuroscientists.
I hope this piece captures even a small part of his remarkable legacy.
www.nature.com/articles/s41...
I hope this piece captures even a small part of his remarkable legacy.
www.nature.com/articles/s41...
Susumu Tonegawa (1939–2026) - Nature Neuroscience
On 11 July 2026, neuroscience lost one of its most visionary scientists with the passing of Susumu Tonegawa at the age of 86. Across an extraordinary career spanning more than five decades, Tonegawa p...
www.nature.com
August 11, 2026 at 1:51 PM
It was an honor to write this remembrance of Susumu Tonegawa (1939–2026) -- a scientist whose discoveries transformed biology and whose lab shaped generations of neuroscientists.
I hope this piece captures even a small part of his remarkable legacy.
www.nature.com/articles/s41...
I hope this piece captures even a small part of his remarkable legacy.
www.nature.com/articles/s41...
Reposted by Elias Spiliotis
Highly cool. 'Cytoskeletal' proteins in the nucleus, 'synaptic' proteins in the cilium. Issue is going to be how to dissect exactly where each protein acts for specific phenotypes
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Nuclear proteome reveals microtubule-associated protein regulating fate and disease
Cellular differentiation and morphogenesis require the coordination between cytoskeletal remodeling and transcriptional programs, raising the question…
www.sciencedirect.com
August 11, 2026 at 6:43 PM
Highly cool. 'Cytoskeletal' proteins in the nucleus, 'synaptic' proteins in the cilium. Issue is going to be how to dissect exactly where each protein acts for specific phenotypes
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The Greeks are always ahead of their time…!
August 10, 2026 at 6:19 PM
The Greeks are always ahead of their time…!
Greatest thing since ketchup slice…
the ketchup slices have hit socials with a vengeance www.instagram.com/reel/DW8biBS...
August 7, 2026 at 10:33 AM
Greatest thing since ketchup slice…
Reposted by Elias Spiliotis
Rest in peace to Country Joe McDonald, the legendary singer-songwriter, activist and frontman of Country Joe and the Fish, who has died at 84.
August 7, 2026 at 2:25 AM
Rest in peace to Country Joe McDonald, the legendary singer-songwriter, activist and frontman of Country Joe and the Fish, who has died at 84.
Reposted by Elias Spiliotis
www.biorxiv.org/content/10.1...
Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments
Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments
August 6, 2026 at 2:48 PM
www.biorxiv.org/content/10.1...
Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments
Structural basis for alpha-actinin inhibition of cooperative cofilin binding to actin filaments
Reposted by Elias Spiliotis
www.biorxiv.org/content/10.6...
Mechanism of branched actin assembly at microtubule tips downstream of Adenomatous Polyposis Coli (APC) protein
Mechanism of branched actin assembly at microtubule tips downstream of Adenomatous Polyposis Coli (APC) protein
August 4, 2026 at 11:37 AM
www.biorxiv.org/content/10.6...
Mechanism of branched actin assembly at microtubule tips downstream of Adenomatous Polyposis Coli (APC) protein
Mechanism of branched actin assembly at microtubule tips downstream of Adenomatous Polyposis Coli (APC) protein
Just found out about Carnegie Embryology's closing at Hopkins. I did my first grad school rotation there with Andy Fire & Yixian Zheng. And took the legendary Molecular Morphogenesis course. It was such a jolt. The smell of this place is still in my head. Sad.
www.bizjournals.com/baltimore/ne...
www.bizjournals.com/baltimore/ne...
Storied research institute leaves Hopkins campus after 100 years - Baltimore Business Journal
After over 100 years of research that led to a Nobel Prize and dozens of other discoveries, one of the world's top research institutions is leaving Baltimore.
www.bizjournals.com
August 4, 2026 at 2:07 AM
Just found out about Carnegie Embryology's closing at Hopkins. I did my first grad school rotation there with Andy Fire & Yixian Zheng. And took the legendary Molecular Morphogenesis course. It was such a jolt. The smell of this place is still in my head. Sad.
www.bizjournals.com/baltimore/ne...
www.bizjournals.com/baltimore/ne...
Reposted by Elias Spiliotis
Carolyn Ott @hhmijanelia.bsky.social, Jennifer Lippincott-Schwartz & David Breslow @davidbreslowlab.bsky.social explain how recent advances have expanded our models of primary cilia disassemble and discuss emerging roles of altered disassembly in disease.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
July 28, 2026 at 2:02 PM
Carolyn Ott @hhmijanelia.bsky.social, Jennifer Lippincott-Schwartz & David Breslow @davidbreslowlab.bsky.social explain how recent advances have expanded our models of primary cilia disassemble and discuss emerging roles of altered disassembly in disease.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Elias Spiliotis
All registration deadlines are listed below. Stay tuned for more posts about our other invited speaker, Dr. Matthew Tyska, and our Keynote speaker, Dr. James Sellers!
We are excited to see you at this year's meeting! Please reach out to [email protected] with any questions.
(3/3)
We are excited to see you at this year's meeting! Please reach out to [email protected] with any questions.
(3/3)
July 27, 2026 at 7:38 PM
All registration deadlines are listed below. Stay tuned for more posts about our other invited speaker, Dr. Matthew Tyska, and our Keynote speaker, Dr. James Sellers!
We are excited to see you at this year's meeting! Please reach out to [email protected] with any questions.
(3/3)
We are excited to see you at this year's meeting! Please reach out to [email protected] with any questions.
(3/3)
Reposted by Elias Spiliotis
SEPT9 is a septin amplified in breast cancer. The Spiliotis lab combines live imaging of confined migrating cells, Clinicogenomic data, and more to tease apart SEPT9's mechanoprotective role.
Register to hear more about this exciting research at this year's TCM:
forms.gle/QGELSmPhAMGK...
(2/3)
Register to hear more about this exciting research at this year's TCM:
forms.gle/QGELSmPhAMGK...
(2/3)
2026 Triangle Cytoskeleton Registration
Thank you for your interest in the 2026 Triangle Cytoskeleton Meeting! Please fill out the information in the form below. To finish registration and pay for attendance please go to:
...
forms.gle
July 27, 2026 at 7:38 PM
SEPT9 is a septin amplified in breast cancer. The Spiliotis lab combines live imaging of confined migrating cells, Clinicogenomic data, and more to tease apart SEPT9's mechanoprotective role.
Register to hear more about this exciting research at this year's TCM:
forms.gle/QGELSmPhAMGK...
(2/3)
Register to hear more about this exciting research at this year's TCM:
forms.gle/QGELSmPhAMGK...
(2/3)
Looking foreword to visit and present in North Carolina! And grateful for the invitation 🙏
Have you ever wondered how cells protect their nuclei from damage while squeezing through tightly packed tissues? @septinlab.bsky.social at the University of Virginia have!
Dr. Elias Spiliotis will share how septin filaments anchor and protect nuclei during migration at TCM 2026!
(1/3)
Dr. Elias Spiliotis will share how septin filaments anchor and protect nuclei during migration at TCM 2026!
(1/3)
July 28, 2026 at 1:57 PM
Looking foreword to visit and present in North Carolina! And grateful for the invitation 🙏
I just discovered my 140 record reviews as a dj at Stanford's KZSU (ca 2002-2008)
If I never get to that number of publications, please throw me a retirement as a "music writer"...
zookeeper.stanford.edu:8443?action=viewR...
If I never get to that number of publications, please throw me a retirement as a "music writer"...
zookeeper.stanford.edu:8443?action=viewR...
zookeeper.stanford.edu
July 26, 2026 at 2:56 AM
I just discovered my 140 record reviews as a dj at Stanford's KZSU (ca 2002-2008)
If I never get to that number of publications, please throw me a retirement as a "music writer"...
zookeeper.stanford.edu:8443?action=viewR...
If I never get to that number of publications, please throw me a retirement as a "music writer"...
zookeeper.stanford.edu:8443?action=viewR...
Reposted by Elias Spiliotis
www.sciencedirect.com/science/arti...
The actin crosslinker Fimbrin is required for force sensing at tricellular junctions
The actin crosslinker Fimbrin is required for force sensing at tricellular junctions
July 25, 2026 at 11:21 AM
www.sciencedirect.com/science/arti...
The actin crosslinker Fimbrin is required for force sensing at tricellular junctions
The actin crosslinker Fimbrin is required for force sensing at tricellular junctions