Journal of Cell Biology
@jcb.org
Journal of Cell Biology publishes peer-reviewed research on all aspects of cellular structure and function. Published by Rockefeller University Press @rupress.org
🌐 https://rupress.org/jcb
🌐 https://rupress.org/jcb
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📢 Attention #undergraduates, #gradstudents, and early-career #postdocs! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards ✈️ that support your attendance at #CellBio2026 (Dec. 12-15) in San Diego! Apply by October 18 👉 rupress.org/jcb/pages/al...
@ascbiology.bsky.social
@ascbiology.bsky.social
Chadha, Schmoller et al. follow budding #yeast cell lineages as they adapt their size in response to a nutrient shift. They show that size regulators that seem redundant in steady-state can have specific roles for cell size adaptation. rupress.org/jcb/article/...
October 9, 2026 at 4:00 PM
Chadha, Schmoller et al. follow budding #yeast cell lineages as they adapt their size in response to a nutrient shift. They show that size regulators that seem redundant in steady-state can have specific roles for cell size adaptation. rupress.org/jcb/article/...
How cells adapt their membranes to prolonged stress is poorly understood. Williams, Klose, Ernst, and Carvalho @dunnschool.bsky.social show that chronic hyperosmotic stress triggers #LipidDroplet accumulation and a shift toward phosphatidylcholine in budding #yeast. rupress.org/jcb/article/...
October 8, 2026 at 4:00 PM
How cells adapt their membranes to prolonged stress is poorly understood. Williams, Klose, Ernst, and Carvalho @dunnschool.bsky.social show that chronic hyperosmotic stress triggers #LipidDroplet accumulation and a shift toward phosphatidylcholine in budding #yeast. rupress.org/jcb/article/...
Yuanjiao Du, Tiantian Zhou, Yazhou Liu et al. identify the atypical VAP-family protein MOSPD3 as an ER receptor for the lipid-transfer protein ATG2A, anchoring it at ER–phagophore contacts to support #autophagy . rupress.org/jcb/article/...
#ER_literature
#ER_literature
October 8, 2026 at 2:30 PM
Yuanjiao Du, Tiantian Zhou, Yazhou Liu et al. identify the atypical VAP-family protein MOSPD3 as an ER receptor for the lipid-transfer protein ATG2A, anchoring it at ER–phagophore contacts to support #autophagy . rupress.org/jcb/article/...
#ER_literature
#ER_literature
A structural model for the autoinhibition of the γ-TuRC-activating CM1 domain. New study by Abir Elfarkouchi, Arthur Vitard, Françoise Ochsenbein @francoizochsenbein.bsky.social @univparissaclay.bsky.social, Paul Conduit @pconduit.bsky.social @ijmonod.bsky.social et al. rupress.org/jcb/article/...
October 7, 2026 at 1:30 PM
A structural model for the autoinhibition of the γ-TuRC-activating CM1 domain. New study by Abir Elfarkouchi, Arthur Vitard, Françoise Ochsenbein @francoizochsenbein.bsky.social @univparissaclay.bsky.social, Paul Conduit @pconduit.bsky.social @ijmonod.bsky.social et al. rupress.org/jcb/article/...
You Wu and David J. Reiner @tamu.bsky.social provide in vivo evidence for the long-proposed role of the Ras effector Ral, a small #GTPase, in regulating the metazoan #exocyst complex. rupress.org/jcb/article/...
#Celegans #Development #Trafficking
#Celegans #Development #Trafficking
October 6, 2026 at 4:00 PM
You Wu and David J. Reiner @tamu.bsky.social provide in vivo evidence for the long-proposed role of the Ras effector Ral, a small #GTPase, in regulating the metazoan #exocyst complex. rupress.org/jcb/article/...
#Celegans #Development #Trafficking
#Celegans #Development #Trafficking
How cells increase energy production to meet the demands of force response is incompletely understood. Dawson, DeMali et al. suggest that the muscle isoform of the glycolytic enzyme phosphofructokinase (PFK) is recruited to #actin, thereby serving this important role. rupress.org/jcb/article/...
October 5, 2026 at 4:00 PM
How cells increase energy production to meet the demands of force response is incompletely understood. Dawson, DeMali et al. suggest that the muscle isoform of the glycolytic enzyme phosphofructokinase (PFK) is recruited to #actin, thereby serving this important role. rupress.org/jcb/article/...
📢 Attention #undergraduates, #gradstudents, and early-career #postdocs! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards ✈️ that support your attendance at #CellBio2026 (Dec. 12-15) in San Diego! Apply by October 18 👉 rupress.org/jcb/pages/al...
@ascbiology.bsky.social
@ascbiology.bsky.social
October 5, 2026 at 2:31 PM
📢 Attention #undergraduates, #gradstudents, and early-career #postdocs! Apply for JCB’s Alan Hall & Norton B. Gilula Travel Awards ✈️ that support your attendance at #CellBio2026 (Dec. 12-15) in San Diego! Apply by October 18 👉 rupress.org/jcb/pages/al...
@ascbiology.bsky.social
@ascbiology.bsky.social
Our October issue is here! rupress.org/jcb/issue/22...
The cover shows #Xenopus blastula embryos undergoing zygotic genome activation (ZGA). Top: normal embryo; bottom: inverted embryo.
From Wenchao Qian, Matthew C. Good @buenoscience.bsky.social & colleagues (doi.org/10.1083/jcb....)
The cover shows #Xenopus blastula embryos undergoing zygotic genome activation (ZGA). Top: normal embryo; bottom: inverted embryo.
From Wenchao Qian, Matthew C. Good @buenoscience.bsky.social & colleagues (doi.org/10.1083/jcb....)
October 5, 2026 at 2:02 PM
Our October issue is here! rupress.org/jcb/issue/22...
The cover shows #Xenopus blastula embryos undergoing zygotic genome activation (ZGA). Top: normal embryo; bottom: inverted embryo.
From Wenchao Qian, Matthew C. Good @buenoscience.bsky.social & colleagues (doi.org/10.1083/jcb....)
The cover shows #Xenopus blastula embryos undergoing zygotic genome activation (ZGA). Top: normal embryo; bottom: inverted embryo.
From Wenchao Qian, Matthew C. Good @buenoscience.bsky.social & colleagues (doi.org/10.1083/jcb....)
Components of an #ESCRT-independent #NuclearEnvelope assembly pathway. New study from Emma M. Sydir, I-Ju Lee, David Pellman @danafarber.bsky.social @harvard.edu and colleagues:
rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
October 2, 2026 at 1:45 PM
Components of an #ESCRT-independent #NuclearEnvelope assembly pathway. New study from Emma M. Sydir, I-Ju Lee, David Pellman @danafarber.bsky.social @harvard.edu and colleagues:
rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
“The monitoring editors are highly professional, thoughtfully synthesizing reviewer comments and providing clear guidance that helped us prioritize our revision efforts.”— Dr. Zhi Hong
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
October 2, 2026 at 1:45 PM
“The monitoring editors are highly professional, thoughtfully synthesizing reviewer comments and providing clear guidance that helped us prioritize our revision efforts.”— Dr. Zhi Hong
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
Reposted by Journal of Cell Biology
Happy to see our latest work published in @jcb.org. Led by an excellent PhD student, Abir Elfarkouchi, and in collaboration with @francoizochsenbein.bsky.social and co-first author Arthur Vitard, we investigated the structural mechanism of CM1 domain autoinhibition rupress.org/jcb/article/...
Journal of Cell Biology | Rockefeller University Press
Journal of Cell Biology (JCB) publishes advances in any area of basic cell biology as well as applied cellular advances in fields such as immunology, neurobiology, metabolism, microbiology, developmen...
rupress.org
October 1, 2026 at 8:28 AM
Happy to see our latest work published in @jcb.org. Led by an excellent PhD student, Abir Elfarkouchi, and in collaboration with @francoizochsenbein.bsky.social and co-first author Arthur Vitard, we investigated the structural mechanism of CM1 domain autoinhibition rupress.org/jcb/article/...
Abir Elfarkouchi, Arthur Vitard, @francoizochsenbein.bsky.social, @pconduit.bsky.social et al. reveal the first structural model for γ-TuRC CM1 domain autoinhibition, which prevents ectopic binding and activation of #microtubule-nucleating γ-tubulin ring complexes. rupress.org/jcb/article/...
September 30, 2026 at 4:00 PM
Abir Elfarkouchi, Arthur Vitard, @francoizochsenbein.bsky.social, @pconduit.bsky.social et al. reveal the first structural model for γ-TuRC CM1 domain autoinhibition, which prevents ectopic binding and activation of #microtubule-nucleating γ-tubulin ring complexes. rupress.org/jcb/article/...
Reposted by Journal of Cell Biology
“The broader lesson may be that interrogating stress responses by unleashing chemical or genetic catastrophe on the cells tells you what the pathways can do but not necessarily what the cell uses them for.”
Subtlety is underrated: physiological UPR activation in #meiosis. David Pincus (University of Chicago) and Vladimir Denic @harvardmcb.bsky.social discuss new work by Bartolutti, Brar and colleagues (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
#Genetics #ProteinHomeostasis
#Genetics #ProteinHomeostasis
September 30, 2026 at 2:38 PM
“The broader lesson may be that interrogating stress responses by unleashing chemical or genetic catastrophe on the cells tells you what the pathways can do but not necessarily what the cell uses them for.”
Subtlety is underrated: physiological UPR activation in #meiosis. David Pincus (University of Chicago) and Vladimir Denic @harvardmcb.bsky.social discuss new work by Bartolutti, Brar and colleagues (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
#Genetics #ProteinHomeostasis
#Genetics #ProteinHomeostasis
September 30, 2026 at 1:45 PM
Subtlety is underrated: physiological UPR activation in #meiosis. David Pincus (University of Chicago) and Vladimir Denic @harvardmcb.bsky.social discuss new work by Bartolutti, Brar and colleagues (rupress.org/jcb/article/...) in Spotlight: rupress.org/jcb/article/...
#Genetics #ProteinHomeostasis
#Genetics #ProteinHomeostasis
Sydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
September 25, 2026 at 4:00 PM
Sydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid
📢 Supporting the #nextgeneration of researchers, JCB offers the Hall & Gilula Travel Awards ✈️ that assist #undergraduates, #gradstudents, and early-career #postdocs in attending #CellBio2026 (Dec. 12-15)! Apply by October 18 👉 rupress.org/jcb/pages/al...
September 24, 2026 at 1:15 PM
📢 Supporting the #nextgeneration of researchers, JCB offers the Hall & Gilula Travel Awards ✈️ that assist #undergraduates, #gradstudents, and early-career #postdocs in attending #CellBio2026 (Dec. 12-15)! Apply by October 18 👉 rupress.org/jcb/pages/al...
Spotlight: Bartolutti, Brar et al. @berkeleymcb.bsky.social (rupress.org/jcb/article/...) describe how physiological UPR induction drives #gametogenesis in budding #yeast. David Pincus and Vladimir Denic discuss the work: rupress.org/jcb/article/...
#Genetics #ProteinHomeostasis
#Genetics #ProteinHomeostasis
September 23, 2026 at 4:01 PM
Spotlight: Bartolutti, Brar et al. @berkeleymcb.bsky.social (rupress.org/jcb/article/...) describe how physiological UPR induction drives #gametogenesis in budding #yeast. David Pincus and Vladimir Denic discuss the work: rupress.org/jcb/article/...
#Genetics #ProteinHomeostasis
#Genetics #ProteinHomeostasis
Visualizing the #Golgi apparatus and Golgiphagy in vivo. New study on reporter mouse models developed by Pengwei Zhao, Mengyuan Zhang, Rongbin Ding, Lingling Zhang, Yongjuan Sang, Qiming Sun and colleagues (Zhejiang University):
rupress.org/jcb/article/...
#Technology #Organelles
rupress.org/jcb/article/...
#Technology #Organelles
September 23, 2026 at 1:45 PM
Visualizing the #Golgi apparatus and Golgiphagy in vivo. New study on reporter mouse models developed by Pengwei Zhao, Mengyuan Zhang, Rongbin Ding, Lingling Zhang, Yongjuan Sang, Qiming Sun and colleagues (Zhejiang University):
rupress.org/jcb/article/...
#Technology #Organelles
rupress.org/jcb/article/...
#Technology #Organelles
Rhomboid protease Rhbdl2 influences #macrophage recruitment and wound repair in #zebrafish. New study from Saroj Gourkanti, Sonya E. Neal @neal-lab.bsky.social @ucsdhealthsci.bsky.social and colleagues:
rupress.org/jcb/article/...
#Migration #motility #Immunology
rupress.org/jcb/article/...
#Migration #motility #Immunology
September 18, 2026 at 2:03 PM
Rhomboid protease Rhbdl2 influences #macrophage recruitment and wound repair in #zebrafish. New study from Saroj Gourkanti, Sonya E. Neal @neal-lab.bsky.social @ucsdhealthsci.bsky.social and colleagues:
rupress.org/jcb/article/...
#Migration #motility #Immunology
rupress.org/jcb/article/...
#Migration #motility #Immunology
“Since starting my independent lab in 2018, I have published two papers in this journal, and the process has consistently been smooth and constructive.”— Dr. Zhi Hong (Zhejiang University-University of Edinburgh Institute)
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
September 17, 2026 at 8:01 PM
“Since starting my independent lab in 2018, I have published two papers in this journal, and the process has consistently been smooth and constructive.”— Dr. Zhi Hong (Zhejiang University-University of Edinburgh Institute)
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
JCB is your partner for peer review. Learn more: hubs.la/Q04rdtS30
📢 Do you know any #undergraduates, #gradstudents, or early-career #postdocs looking to attend #CellBio2026? We're now accepting applications for our Travel Awards that could support their participation ✈️
⏰ Deadline: Oct. 18 👉 rupress.org/jcb/pages/al...
⏰ Deadline: Oct. 18 👉 rupress.org/jcb/pages/al...
September 16, 2026 at 8:30 PM
📢 Do you know any #undergraduates, #gradstudents, or early-career #postdocs looking to attend #CellBio2026? We're now accepting applications for our Travel Awards that could support their participation ✈️
⏰ Deadline: Oct. 18 👉 rupress.org/jcb/pages/al...
⏰ Deadline: Oct. 18 👉 rupress.org/jcb/pages/al...
Nucleolar dynamics are determined by the ordered assembly of the #ribosome. New study from Jessica Sheu-Gruttadauria and collegues (UCSF):
rupress.org/jcb/article/...
#Biophysics #RNAbiology #Nucleolus
rupress.org/jcb/article/...
#Biophysics #RNAbiology #Nucleolus
September 16, 2026 at 8:30 PM
Nucleolar dynamics are determined by the ordered assembly of the #ribosome. New study from Jessica Sheu-Gruttadauria and collegues (UCSF):
rupress.org/jcb/article/...
#Biophysics #RNAbiology #Nucleolus
rupress.org/jcb/article/...
#Biophysics #RNAbiology #Nucleolus
Reposted by Journal of Cell Biology
Huge kudos to JCB. Not only was the review process super constructive, they enthusiastically embraced the underutilized #GolgiTime hashtag 😀
Avl9 defines a family of DENN domain GTPase-activating proteins. New study from Ryan C. Vignogna (@rvig.bsky.social) & J. Christopher Fromme (@fromme-lab.bsky.social) @cornelluniversity.bsky.social:
rupress.org/jcb/article/...
#GolgiTime #GTPases #Migration #Biochemistry #StructuralBiology #Golgi
rupress.org/jcb/article/...
#GolgiTime #GTPases #Migration #Biochemistry #StructuralBiology #Golgi
September 16, 2026 at 3:04 PM
Huge kudos to JCB. Not only was the review process super constructive, they enthusiastically embraced the underutilized #GolgiTime hashtag 😀
Pengwei Zhao, Mengyuan Zhang, Rongbin Ding et al. develop constitutive and inducible #Golgi reporter mice that enable in vivo visualization of Golgi architecture and Golgiphagy at single-cell resolution. rupress.org/jcb/article/...
#Technology #Organelles
#Technology #Organelles
September 16, 2026 at 4:00 PM
Pengwei Zhao, Mengyuan Zhang, Rongbin Ding et al. develop constitutive and inducible #Golgi reporter mice that enable in vivo visualization of Golgi architecture and Golgiphagy at single-cell resolution. rupress.org/jcb/article/...
#Technology #Organelles
#Technology #Organelles
Dysfunction of #caveolae in muscle disease: a cell biological perspective. From Harriet P. Lo, Robert G. Parton and colleagues (The University of Queensland)
rupress.org/jcb/article/...
#Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle
rupress.org/jcb/article/...
#Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle
September 16, 2026 at 2:31 PM
Dysfunction of #caveolae in muscle disease: a cell biological perspective. From Harriet P. Lo, Robert G. Parton and colleagues (The University of Queensland)
rupress.org/jcb/article/...
#Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle
rupress.org/jcb/article/...
#Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle