Yinpu Tang
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yinputang.bsky.social
Yinpu Tang
@yinputang.bsky.social
15 followers 28 following 28 posts
PhD Candidate & Elephant🐘 Amateur
Department of Biological Sciences
University at Buffalo
Posts Replies Media Videos
Reposted by Yinpu Tang
devoevomed.bsky.social
Oh my, whoever could have predicted this‽ #ColossalBio is backtracking on it's time frame to #DeExtinct the mammoth –– I'm shocked! Shocked I say! (The article also discusses our TP53 and LIF6 work, and #PetosParadox but doesn't mention either of us.) 🤷 🦣 😂

time.com/article/2026...
Miss J Alexander's Shocked Drama Reaction
ALT: Miss J Alexander's Shocked Drama Reaction
static.klipy.com
August 28, 2026 at 3:00 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
“I hate to say this, because I don’t want to call the mammoth a product,” says Lamm, “but it will be a better product because of our deeper analysis of what truly made a mammoth a mammoth.”
Underdone Comics: GMO Mammoth
ALT: Underdone Comics: GMO Mammoth
static.klipy.com
August 28, 2026 at 3:02 PM
Reposted by Yinpu Tang
errantv.bsky.social
Only if you didn't validate your antibodies when you ordered them (which like, if you didn't, yikes)

We could also all just stop doing fucking western blots lol, they're such a bad, qualitative, poorly reproducible assay that should've been dumped for better options a decade or two ago.
August 25, 2026 at 2:40 PM
Reposted by Yinpu Tang
dangaristo.bsky.social
In May it was big news when 100+ suspicious images were found in Thermo Fisher's catalog. Now, that number has expanded dramatically to 18,000+, thanks to some arduous searching by @reeserichardson.bsky.social.

My reporting on the massive trove and its implications for antibody reliability:
More than 18,000 questionable images found in antibody catalogues of 15 companies
Science sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.
www.nature.com
August 25, 2026 at 1:07 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
Fun fact: Afrotheria have lost AIM2 🤷

www.biorxiv.org/content/10.1...
labwaggoner.bsky.social Waggoner Lab @labwaggoner.bsky.social · Aug 19
AIM2 promotes airway hyperresponsiveness and lung inflammation by enhancing type II cytokines, immune cell populations, and the DNA damage response @pnas.org @ting-lab-unc.bsky.social
www.pnas.org/doi/10.1073/...
August 19, 2026 at 4:08 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
💯
July 17, 2026 at 6:12 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
Especially when the “fix” is impossible 🦣 🧪 🤷
July 8, 2026 at 11:45 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
My thoughts exactly
July 1, 2026 at 11:49 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
Well now, this is worth a deep dive into #EvMed #PetosParadox #DevoEvo

www.biorxiv.org/content/10.6...
Indirect genomic effects shape cancer risk across species
Tumour prevalence varies dramatically throughout the animal kingdom despite broadly conserved cellular and developmental processes, raising the question of how evolution has shaped susceptibility 1,2....
www.biorxiv.org
July 1, 2026 at 11:59 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
Good idea and thanks for the reference, we will give it a try!
July 1, 2026 at 6:43 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
We've never gotten mTagBFP to work :-/
July 1, 2026 at 6:28 PM
Reposted by Yinpu Tang
lovedalen.bsky.social
This is what we have found so far in mammoths (but we keep sequencing additional mammoths, so it might be we’ll find more pathogens in the future):

www.cell.com/cell/fulltex...
Ancient host-associated microbes obtained from mammoth remains
A study of 483 mammoth remains spanning over a million years reveals ancient host-associated microbes preserved in bones and teeth, offering new insights into the long-term evolution of Pleistocene mi...
www.cell.com
June 22, 2026 at 4:30 AM
Reposted by Yinpu Tang
devoevomed.bsky.social
Oh, #ColossalBio has at least one pending patent, that plaragizes a figure from one of our papers: their Fig. 1A vs our Fig. 9A

patents.google.com/patent/US202...

pmc.ncbi.nlm.nih.gov/articles/PMC...
errantv.bsky.social Errant @errantv.bsky.social · Jun 17
It's really obvious that Colossal is a marketing grift to extract VC cash. They have constant media strategies but no products, no patents, and no research publications!
June 17, 2026 at 4:51 PM
Reposted by Yinpu Tang
sholtodavid.bsky.social
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.
May 17, 2026 at 5:53 PM
Reposted by Yinpu Tang
jdbowman1908.bsky.social
What this 'press' article doesn't seem to get is that Vinny criticizes out of a place of genuine desire to make science more accessible and less hand-wavy bullshit. @itiscolossal.bsky.social is gonna make fake promises and cause more mistrust in science.
May 16, 2026 at 2:16 AM
Reposted by Yinpu Tang
marmole6.bsky.social
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social

www.cell.com/cell/fulltex...

If you want to know more, read the 🧵 below:
November 14, 2025 at 4:08 PM
Reposted by Yinpu Tang
devoevomed.bsky.social
lol, we did some stuff. This is also a good reference:

www.pnas.org/doi/10.1073/...
A comprehensive genomic history of extinct and living elephants | PNAS
Elephantids are the world’s most iconic megafaunal family, yet there is no comprehensive genomic assessment of their relationships. We report a tot...
www.pnas.org
March 5, 2026 at 7:22 PM