Corentin Jaboulay
@cjresearch.bsky.social
PhD in Microbiology and Infectiology, Posdoc in Justine Collier's lab @UNIL Lausanne, interested in bacteria cell-cycle, c-diGMP signaling and molecular microbiology.
https://orcid.org/0000-0001-5615-7371
https://orcid.org/0000-0001-5615-7371
Reposted by Corentin Jaboulay
🦠 How can we measure #nutrient #availability at the scale of individual #gut #bacteria?
New publication @dmf-unil.bsky.social in @plosbiology.org on #honeybee 🐝 by research groups @pengellab.bsky.social & @yschaerli.bsky.social
👉 journals.plos.org/plosbiology/...
New publication @dmf-unil.bsky.social in @plosbiology.org on #honeybee 🐝 by research groups @pengellab.bsky.social & @yschaerli.bsky.social
👉 journals.plos.org/plosbiology/...
An engineered bacterial symbiont maps micron-scale sugar gradients in the honeybee gut
A prior PLOS Biology study engineered bee gut bacteria to sense their microenvironment. This new study engineers a native honey bee symbiont into a living biosensor for arabinose, revealing its spatia...
journals.plos.org
September 17, 2026 at 9:13 AM
🦠 How can we measure #nutrient #availability at the scale of individual #gut #bacteria?
New publication @dmf-unil.bsky.social in @plosbiology.org on #honeybee 🐝 by research groups @pengellab.bsky.social & @yschaerli.bsky.social
👉 journals.plos.org/plosbiology/...
New publication @dmf-unil.bsky.social in @plosbiology.org on #honeybee 🐝 by research groups @pengellab.bsky.social & @yschaerli.bsky.social
👉 journals.plos.org/plosbiology/...
Reposted by Corentin Jaboulay
Using Claude science for a « in silico » structural biology project.
Definitely very useful to automate processing pipelines and data processing.
But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
Definitely very useful to automate processing pipelines and data processing.
But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
September 15, 2026 at 6:02 AM
Using Claude science for a « in silico » structural biology project.
Definitely very useful to automate processing pipelines and data processing.
But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
Definitely very useful to automate processing pipelines and data processing.
But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
Reposted by Corentin Jaboulay
Our paper (and my first first-author) is out!
The alarmone pGpp inhibits translation through GTP depletion
academic.oup.com/nar/article/...
🦠🚨🤠
@narjournal.bsky.social
The alarmone pGpp inhibits translation through GTP depletion
academic.oup.com/nar/article/...
🦠🚨🤠
@narjournal.bsky.social
academic.oup.com
September 13, 2026 at 12:30 PM
Our paper (and my first first-author) is out!
The alarmone pGpp inhibits translation through GTP depletion
academic.oup.com/nar/article/...
🦠🚨🤠
@narjournal.bsky.social
The alarmone pGpp inhibits translation through GTP depletion
academic.oup.com/nar/article/...
🦠🚨🤠
@narjournal.bsky.social
Reposted by Corentin Jaboulay
New paper in Current Biology @currentbiology.bsky.social 🦠 Why do bacteria ditch their T6SS weapon? E. coli keeps it vs susceptible rivals, but loses it when facing immune ones. Great work by @bobytaillefer.bsky.social & Jonas Desjardins!
www.cell.com/current-biol...
www.cell.com/current-biol...
Experimental evolution reveals genetic routes for adaptive loss of the antibacterial type VI secretion system
Taillefer et al. show that a bacterial type VI secretion system is lost or attenuated
during experimental evolution when it provides no competitive advantage but is maintained
in the presence of susce...
www.cell.com
September 11, 2026 at 4:05 AM
New paper in Current Biology @currentbiology.bsky.social 🦠 Why do bacteria ditch their T6SS weapon? E. coli keeps it vs susceptible rivals, but loses it when facing immune ones. Great work by @bobytaillefer.bsky.social & Jonas Desjardins!
www.cell.com/current-biol...
www.cell.com/current-biol...
Reposted by Corentin Jaboulay
So excited to share our new preprint! 🎉🤩 Check it out to discover how we investigated the role and spatiotemporal dynamics of an essential Tad nanomachine during the lifecycle of our favorite bacterial predator, B.bacteriovorus 🦠 Many thanks to everyone who made this work possible!
New preprint! We show that the bacterial predator B. bacteriovorus deploys a unipolar Tad nanomachine for irreversible attachment to prey and invasion.
@coralietesseur.bsky.social used CRISPRi+microfluidics to overcome barriers associated with essential systems in an obligate predatory lifestyle 🦠
@coralietesseur.bsky.social used CRISPRi+microfluidics to overcome barriers associated with essential systems in an obligate predatory lifestyle 🦠
A polarity-controlled Tad nanomachine enables prey invasion in a bacterial predator
Type IV pili are dynamic surface appendages assembled by envelope-spanning nanomachines that mediate diverse bacterial interactions, yet how these systems are adapted to predatory lifestyles remains p...
www.biorxiv.org
July 9, 2026 at 4:02 PM
So excited to share our new preprint! 🎉🤩 Check it out to discover how we investigated the role and spatiotemporal dynamics of an essential Tad nanomachine during the lifecycle of our favorite bacterial predator, B.bacteriovorus 🦠 Many thanks to everyone who made this work possible!
Reposted by Corentin Jaboulay
I am delighted to share our latest preprint:
doi.org/10.64898/202....
Fantastic work from my past and present lab members @flofournes.bsky.social, Sandra Martin and Nicolas Pellaton. Also many thanks to our precious collaborators @gruberlab.bsky.social and to @snsf.ch for funding this research.
doi.org/10.64898/202....
Fantastic work from my past and present lab members @flofournes.bsky.social, Sandra Martin and Nicolas Pellaton. Also many thanks to our precious collaborators @gruberlab.bsky.social and to @snsf.ch for funding this research.
June 2, 2026 at 8:29 AM
I am delighted to share our latest preprint:
doi.org/10.64898/202....
Fantastic work from my past and present lab members @flofournes.bsky.social, Sandra Martin and Nicolas Pellaton. Also many thanks to our precious collaborators @gruberlab.bsky.social and to @snsf.ch for funding this research.
doi.org/10.64898/202....
Fantastic work from my past and present lab members @flofournes.bsky.social, Sandra Martin and Nicolas Pellaton. Also many thanks to our precious collaborators @gruberlab.bsky.social and to @snsf.ch for funding this research.
Reposted by Corentin Jaboulay
Check out Snorre's latest preprint: www.biorxiv.org/content/10.6... I love this story: our 4-species synthetic bacterial community coexists across many simple environments and conditions. We show why (spoiler in the title)
April 22, 2026 at 3:37 PM
Check out Snorre's latest preprint: www.biorxiv.org/content/10.6... I love this story: our 4-species synthetic bacterial community coexists across many simple environments and conditions. We show why (spoiler in the title)
Reposted by Corentin Jaboulay
Out Now! Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae #MicroSky
Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae
Nature Microbiology, Published online: 07 April 2026; doi:10.1038/s41564-026-02322-6Sequential peptidoglycan carboxylase activity of DacA and DacB generates a local peptidoglycan signature that recruits MapZ and establishes the division site at the Streptococcus pneumoniae cell equator.
go.nature.com
April 7, 2026 at 6:41 PM
Out Now! Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae #MicroSky
Reposted by Corentin Jaboulay
Cytosine methylation contributes to the fitness of Caulobacter cells naturally expressing a Vsr-like protein: iScience www.cell.com/iscience/ful...
🎊Congrats to my fantastic lab members @noemiematthey.bsky.social , Giorgia Wennubst and Nicolas Pellaton, and to our precious GTF collaborators! 🎉
🎊Congrats to my fantastic lab members @noemiematthey.bsky.social , Giorgia Wennubst and Nicolas Pellaton, and to our precious GTF collaborators! 🎉
Cytosine methylation contributes to the fitness of Caulobacter cells naturally expressing a Vsr-like protein
Properties of biomolecules; Epigenetics; Microbial genomics; Transcriptomics
www.cell.com
February 6, 2026 at 12:31 PM
Cytosine methylation contributes to the fitness of Caulobacter cells naturally expressing a Vsr-like protein: iScience www.cell.com/iscience/ful...
🎊Congrats to my fantastic lab members @noemiematthey.bsky.social , Giorgia Wennubst and Nicolas Pellaton, and to our precious GTF collaborators! 🎉
🎊Congrats to my fantastic lab members @noemiematthey.bsky.social , Giorgia Wennubst and Nicolas Pellaton, and to our precious GTF collaborators! 🎉
Reposted by Corentin Jaboulay
🦠 @laurentterradot.bsky.social lab reviews #Brucella’s #T4SS—a key virulence factor—covering its structure, function, and growing effector arsenal. It also explores how effectors enter host cells, opening new paths to understand and target infection. 🔬
👉 buff.ly/KW4kVN4
👉 buff.ly/KW4kVN4
January 26, 2026 at 8:01 AM
🦠 @laurentterradot.bsky.social lab reviews #Brucella’s #T4SS—a key virulence factor—covering its structure, function, and growing effector arsenal. It also explores how effectors enter host cells, opening new paths to understand and target infection. 🔬
👉 buff.ly/KW4kVN4
👉 buff.ly/KW4kVN4
Reposted by Corentin Jaboulay
New publication from the Lesterlin (TacC) team at MMSB! Congratulations to all authors. In collaboration with Pierre Bogaerts (UCL Belgium) and J. Villa (UB Barcelona)
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
January 26, 2026 at 9:37 AM
New publication from the Lesterlin (TacC) team at MMSB! Congratulations to all authors. In collaboration with Pierre Bogaerts (UCL Belgium) and J. Villa (UB Barcelona)
doi.org/10.1093/nar/...
doi.org/10.1093/nar/...
Reposted by Corentin Jaboulay
Exclusion systems, far from slowing down plasmid spread, are in fact essential to preserve host cell viability and thereby ensure the successful dissemination of conjugative plasmids and antibiotic resistance genes.
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
Exclusion systems preserve host cell homeostasis and fitness, ensuring successful dissemination of conjugative plasmids and associated resistance genes
Abstract. Plasmid conjugation is a major driver of antibiotic resistance dissemination in bacteria. In addition to genes required for transfer and maintena
academic.oup.com
September 17, 2025 at 10:17 AM
Exclusion systems, far from slowing down plasmid spread, are in fact essential to preserve host cell viability and thereby ensure the successful dissemination of conjugative plasmids and antibiotic resistance genes.
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
@nfrk92.bsky.social
@narjournal.bsky.social
academic.oup.com/nar/article/...
Reposted by Corentin Jaboulay
Check out the first preprint from our lab describing a direct molecular cross-talk between (p)ppGpp and c-di-GMP nucleotide messengers! Great work from first-author Corentin Jaboulay who was a postdoc in our lab, and great collaborations! @mmsb-lyon.bsky.social @cnrsbiologie.bsky.social
Cross-regulation of (p)ppGpp and c-di-GMP pathways controls a cell-cycle transition https://www.biorxiv.org/content/10.1101/2025.08.22.671821v1
August 24, 2025 at 7:48 AM
Check out the first preprint from our lab describing a direct molecular cross-talk between (p)ppGpp and c-di-GMP nucleotide messengers! Great work from first-author Corentin Jaboulay who was a postdoc in our lab, and great collaborations! @mmsb-lyon.bsky.social @cnrsbiologie.bsky.social