Delarue Research
banner
delarueresearch.bsky.social
Delarue Research
@delarueresearch.bsky.social
Our research focuses on the impact of compressive stress on the living, and the interplay with intracellular crowding, from an engineering, physical and biological point of view. Check out our website https://delarue-research.org/ for more information!
We wrote a method paper on our different microfluidic technologies to confine microbial cells, and display a novel and unique device to confine and even retrieve cells to perform, for instance, omics analysis on confined cells! Reach out if this is of interest for your research.
Microfluidic Devices for Imaging and Biochemistry Analysis of Microbes Under Mechanical Pressure https://www.biorxiv.org/content/10.64898/2026.09.06.749717v1
September 10, 2026 at 7:37 PM
Our collaborative paper, with Daria Bonazzi and @dumenillab.bsky.social is finally out in Nat Comms! Using microfluidic confiners, amazing Laure Leblanc found that confined growth of E. coli uncouples growth and division, as well as pressure and biomass production. tinyurl.com/4zdwrp39
September 6, 2026 at 12:41 PM
Reposted by Delarue Research
Bacterial growth under confinement requires transcriptional adaptation to resist turgor pressure build-up
doi.org/10.1038/s414...
September 5, 2026 at 10:58 AM
Reposted by Delarue Research
🔬🧪🦠 An exciting opportunity to work at the interface of Fungal Cell Biology & Biophysics in Nice, FR in a collaborative project on roles of cytoplasmic crowding in fungal pathogen morphogenesis, antifungal responses and host interaction.
ibv.unice.fr/news/postdoc...

Please share/retweet
September 1, 2026 at 10:23 AM
Please save the date: The Microphysio Conference is back and will be held in Cargèse from April 25th to April 30th!
With a great lineup of speakers, it’s an excellent opportunity to exchange ideas in fields related to organ-on-chip, organoids, bioprinting, mechanobiology, and much more!
Stay tuned.
August 25, 2026 at 1:44 PM
Now published in Micro-Nano-Engineering! www.sciencedirect.com/science/arti...
August 19, 2026 at 12:06 PM
Reposted by Delarue Research
Un pétition du collège des sociétés savantes pour mettre en avant le rôle de la recherche dans la campagne politique à venir et rappeler le sous investissement chronique en France depuis 20 ans. N'hésitez pas à faire ciculer
recherche-publique-2027.fr
Recherche Publique 2027 – Appel des scientifiques pour la place de la recherche dans la société
recherche-publique-2027.fr
June 26, 2026 at 1:23 PM
Reposted by Delarue Research
#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄
✍️ Robert Arkowitz
📕 @natmicrobiol.nature.com | buff.ly/zPSLael
Fluidité intracellulaire et pouvoir infectieux du champignon Candida albicans
Dans un article publié dans la revue Nature Microbiology, des scientifiques mettent en évidence un mécanisme jusque-là inconnu chez Candida albic
www.insb.cnrs.fr
January 9, 2026 at 1:00 PM
Happy New Year! And happy to share our latest instrumentation work, led by fantastic Ines Muguet. Ines showed that sliding elements, developped by Ben Meriem et al, can be functionnalized to have electrodes, thus allowing reconfigurable electrochemistry-on-chip! Stay tuned, more preprints to come.
Selective Laser Etching technology for reconfigurable microfluidic and electrochemistry-on-chip https://www.biorxiv.org/content/10.64898/2026.01.08.698316v1
January 9, 2026 at 9:53 AM
Reposted by Delarue Research
📢 New extended abstract submission deadline: 6 January 2026! Outstanding speaker list, plus many slots for short talks by students, postdocs, and junior PIs. Join us in March in Barcelona! events.ibecbarcelona.eu/embl-ibec-co...
December 15, 2025 at 10:15 AM
Wonderful collaboration with @robertarkowitz.bsky.social et al! Fascinating result that inhibiting ribosome biogenesis triggers filamentation of C. albicans!
December 11, 2025 at 7:53 PM
New preprint from the lab, an old work from Z. Ben Meriem! We compress cells in 2D and show that proliferation and motility decrease. Crowding increases under pressure, which may explain this result. Interestingly, more mesenchymal cells seem to be more sensitive to pressure!
tinyurl.com/ybfu62yf
April 28, 2025 at 7:07 PM
I want to share three reviews on crowding and spatial confinement, active areas of research on our end:
- on the dynamic structure of the cytoplasm: tinyurl.com/4d6drhnv
- on the sensing of and response to crowding: tinyurl.com/959ht4fw
- on the effect of spatial confinement: tinyurl.com/nhh7sk9w
April 4, 2025 at 7:33 AM
Reposted by Delarue Research
Happy to bring this to light!
The result of quite a few years and fabulous collaborations with wonderful colleagues! Thread from Antonio Serrano (@antonioserrano) coming soon!
November 17, 2024 at 3:48 PM
Reposted by Delarue Research
Pre-announcing the EMBO/EMBL symposium "Mechanobiology Across the Tree of Life", Heidelberg, 9-12 June 2026. It is still very very far away, but save the date 🗓️. With Alba Diz-Munoz, @nicolettapetridou.bsky.social , Kirsty Wan @micromotility.bsky.social, Enrique Rojas.
www.embl.org/about/info/c...
Mechanobiology across the tree of life
www.embl.org
November 20, 2024 at 4:49 PM
Reposted by Delarue Research
🚨 Excited to share our new study on the human fungal pathogen Candida albicans! Thread 👇 (1/11)
biorxiv.org/content/10.1...

#Science #Microbiology #CellBiology
biorxiv.org
November 19, 2024 at 2:47 PM
Reposted by Delarue Research
This work wouldn’t be possible without the incredible collaboration of wonderful colleagues.Thanks to Charles Puerner, Emily Plumb, Louis Chevalier, Johannes Elferich, Ludwig Sinn, Niko Grigorieff, Markus Ralser, @delarueresearch.bsky.social, Martine Bassilana and
@robertarkowitz.bsky.social (9/11)
November 19, 2024 at 2:47 PM