Inmaculada Rodriguez-Martin
@inmaculadaroma.bsky.social
PhD student at Institute of Parasitology and Biomedicine López-Neyra in Granada, Spain
Researching on sex differences in systemic sclerosis
Researching on sex differences in systemic sclerosis
Pinned
What causes more women to develop autoimmune diseases? Currently, the explanation normally includes: hormones, chrX and sex differences in the immune system
Excited to announce that our new work about sex-dependent genetics in scleroderma is finally available in Lancet Rheumatology!! 🥳🙌🏻
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
Really happy to share this with you! If you're interested in our new work about sex-differences in genomic risk to SSc, go and have a look! Hope you enjoy ✨🙌🏻
The work presented by @inmaculadaroma.bsky.social daroma.bsky.social is titled: "Sex-specific HLA risk landscapes in systemic sclerosis" and is now avaible on the WSF Academy Platform: worldsclerofound.org/webinars/
No access - World Sclero Found
worldsclerofound.org
June 15, 2026 at 2:34 PM
Really happy to share this with you! If you're interested in our new work about sex-differences in genomic risk to SSc, go and have a look! Hope you enjoy ✨🙌🏻
Reposted by Inmaculada Rodriguez-Martin
The work presented by @inmaculadaroma.bsky.social daroma.bsky.social is titled: "Sex-specific HLA risk landscapes in systemic sclerosis" and is now avaible on the WSF Academy Platform: worldsclerofound.org/webinars/
No access - World Sclero Found
worldsclerofound.org
June 15, 2026 at 9:11 AM
The work presented by @inmaculadaroma.bsky.social daroma.bsky.social is titled: "Sex-specific HLA risk landscapes in systemic sclerosis" and is now avaible on the WSF Academy Platform: worldsclerofound.org/webinars/
Reposted by Inmaculada Rodriguez-Martin
📢 ¿Sabías que la esclerodermia no afecta igual a hombres y mujeres?
Nuestro último estudio publicado en @thelancetrheum.bsky.social analiza estas diferencias clave para entender mejor la enfermedad
Si queréis saber más, podéis leer la nota de prensa @csic.es @ipblncsic.bsky.social👇📖
Nuestro último estudio publicado en @thelancetrheum.bsky.social analiza estas diferencias clave para entender mejor la enfermedad
Si queréis saber más, podéis leer la nota de prensa @csic.es @ipblncsic.bsky.social👇📖
🏥La #esclerodermia es una #EnfermedadRara que ataca los tejidos
👩🦰Afecta más a mujeres, aunque es más grave en hombres
🔬Un estudio del @ipblncsic.bsky.social arroja luz sobre estas diferencias
🔎Revela marcadores genéticos específicos para cada sexo
➡️ https://f.mtr.cool/qyinfqsttn
👩🦰Afecta más a mujeres, aunque es más grave en hombres
🔬Un estudio del @ipblncsic.bsky.social arroja luz sobre estas diferencias
🔎Revela marcadores genéticos específicos para cada sexo
➡️ https://f.mtr.cool/qyinfqsttn
May 19, 2026 at 8:34 AM
📢 ¿Sabías que la esclerodermia no afecta igual a hombres y mujeres?
Nuestro último estudio publicado en @thelancetrheum.bsky.social analiza estas diferencias clave para entender mejor la enfermedad
Si queréis saber más, podéis leer la nota de prensa @csic.es @ipblncsic.bsky.social👇📖
Nuestro último estudio publicado en @thelancetrheum.bsky.social analiza estas diferencias clave para entender mejor la enfermedad
Si queréis saber más, podéis leer la nota de prensa @csic.es @ipblncsic.bsky.social👇📖
Reposted by Inmaculada Rodriguez-Martin
No sólo supone perder tiempo, esfuerzo y dinero para los investigadores, sino para toda la población (2/2)
Idea desarrollada por @carlotaconciencia (instagram) y yo
Idea desarrollada por @carlotaconciencia (instagram) y yo
May 14, 2026 at 1:18 PM
No sólo supone perder tiempo, esfuerzo y dinero para los investigadores, sino para toda la población (2/2)
Idea desarrollada por @carlotaconciencia (instagram) y yo
Idea desarrollada por @carlotaconciencia (instagram) y yo
Reposted by Inmaculada Rodriguez-Martin
No publicar los resultados negativos es una mala práctica científica que deriva de la forma en que está estructurado el sistema de publicaciones (1/2)
May 14, 2026 at 1:18 PM
No publicar los resultados negativos es una mala práctica científica que deriva de la forma en que está estructurado el sistema de publicaciones (1/2)
Reposted by Inmaculada Rodriguez-Martin
NEW RESEARCH—Sex-specific autosomal susceptibility loci in systemic sclerosis: a genome-wide association study bit.ly/3OHY4ys
Plus, linked Comment bit.ly/4e8AvJK
#Medsky #Rheumsky
Plus, linked Comment bit.ly/4e8AvJK
#Medsky #Rheumsky
April 24, 2026 at 4:42 PM
NEW RESEARCH—Sex-specific autosomal susceptibility loci in systemic sclerosis: a genome-wide association study bit.ly/3OHY4ys
Plus, linked Comment bit.ly/4e8AvJK
#Medsky #Rheumsky
Plus, linked Comment bit.ly/4e8AvJK
#Medsky #Rheumsky
This morning I gave a presentation about how genetics risk factors differ by sex in autoimmunity at the andalusian association for autoimmune diseases Congress ☺️
Thank you for this opportunity!
Thank you for this opportunity!
April 16, 2026 at 11:55 AM
This morning I gave a presentation about how genetics risk factors differ by sex in autoimmunity at the andalusian association for autoimmune diseases Congress ☺️
Thank you for this opportunity!
Thank you for this opportunity!
Excited to announce that our new work about sex-dependent genetics in scleroderma is finally available in Lancet Rheumatology!! 🥳🙌🏻
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
What causes more women to develop autoimmune diseases? Currently, the explanation normally includes: hormones, chrX and sex differences in the immune system
April 16, 2026 at 10:48 AM
Excited to announce that our new work about sex-dependent genetics in scleroderma is finally available in Lancet Rheumatology!! 🥳🙌🏻
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
Take a look to Gonzalo's thread about it!
Thanks everyone who made it possible and thank you Gonzalo for your words ☺️
Reposted by Inmaculada Rodriguez-Martin
El Comité de Igualdad, Diversidad e Inclusión del IPBLN ha organizado un un café informal donde se ha hablado sobre la inclusión de personas LGTBQIA+ en ciencia: algunos de los retos que existen y qué hacer para apoyar mejor a las identidades LGTBQIA+ en nuestros laboratorios.
March 24, 2026 at 11:02 AM
El Comité de Igualdad, Diversidad e Inclusión del IPBLN ha organizado un un café informal donde se ha hablado sobre la inclusión de personas LGTBQIA+ en ciencia: algunos de los retos que existen y qué hacer para apoyar mejor a las identidades LGTBQIA+ en nuestros laboratorios.
Reposted by Inmaculada Rodriguez-Martin
February 11, 2026 at 8:19 AM
Reposted by Inmaculada Rodriguez-Martin
Now out! 🎉 We asked: why is GCA an age-related disease?
Our approach: a cross-trait GWAS to explore shared genetic predisposition between GCA and markers of biological aging
Excited to share this one! 🧬⏳
www.aginganddisease.org/EN/10.14336/...
cc @inmaculadaroma.bsky.social @ipblncsic.bsky.social
Our approach: a cross-trait GWAS to explore shared genetic predisposition between GCA and markers of biological aging
Excited to share this one! 🧬⏳
www.aginganddisease.org/EN/10.14336/...
cc @inmaculadaroma.bsky.social @ipblncsic.bsky.social
Cross-Trait Meta-Analysis Reveals a Genetic Link between Inflammation and Aging in Giant Cell Arteritis
<p>Giant cell arteritis (GCA) is a complex inflammatory disease affecting individuals over 50 suggesting a strong link with aging-related immune and vascular changes. However, the precise mechanisms u...
www.aginganddisease.org
September 1, 2025 at 10:02 AM
Now out! 🎉 We asked: why is GCA an age-related disease?
Our approach: a cross-trait GWAS to explore shared genetic predisposition between GCA and markers of biological aging
Excited to share this one! 🧬⏳
www.aginganddisease.org/EN/10.14336/...
cc @inmaculadaroma.bsky.social @ipblncsic.bsky.social
Our approach: a cross-trait GWAS to explore shared genetic predisposition between GCA and markers of biological aging
Excited to share this one! 🧬⏳
www.aginganddisease.org/EN/10.14336/...
cc @inmaculadaroma.bsky.social @ipblncsic.bsky.social
Reposted by Inmaculada Rodriguez-Martin
¡DESPEDIMOS el curso con una gran felicitación a nuestros compañeros @javiml221098.bsky.social, Marialbert Acosta-Herrera, Carlos de la Rosa Báez e @inmaculadaroma.bsky.social del IPBLN por su notable presencia en el 19th International Workshop on Scleroderma Research! 👏🎊🥳🎉
August 8, 2025 at 9:50 AM
¡DESPEDIMOS el curso con una gran felicitación a nuestros compañeros @javiml221098.bsky.social, Marialbert Acosta-Herrera, Carlos de la Rosa Báez e @inmaculadaroma.bsky.social del IPBLN por su notable presencia en el 19th International Workshop on Scleroderma Research! 👏🎊🥳🎉
Reposted by Inmaculada Rodriguez-Martin
New paper just out (online first) in Arthritis & Rheumatology! 🎉
We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵
Read: doi.org/10.1002/art....
cc @ipblncsic.bsky.social
We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵
Read: doi.org/10.1002/art....
cc @ipblncsic.bsky.social
Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients
Objectives Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by ...
doi.org
August 28, 2025 at 10:40 AM
New paper just out (online first) in Arthritis & Rheumatology! 🎉
We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵
Read: doi.org/10.1002/art....
cc @ipblncsic.bsky.social
We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵
Read: doi.org/10.1002/art....
cc @ipblncsic.bsky.social
These past days I had the amazing opportunity to attend the International Workshop on Scleroderma Research in Cambridge. Thanks to the SCTC for awarding me with a Workshop Travel Award 🙌🏻
July 31, 2025 at 8:41 PM
These past days I had the amazing opportunity to attend the International Workshop on Scleroderma Research in Cambridge. Thanks to the SCTC for awarding me with a Workshop Travel Award 🙌🏻
Reposted by Inmaculada Rodriguez-Martin
So excited to share our latest study on defining the function of disease variants by editing single cells, and assuming them with CRAFT-seq! Special thanks to @zpmu.bsky.social and @baglaenkolab.bsky.social! @broadinstitute.org
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Precisely defining disease variant effects in CRISPR-edited single cells - Nature
A plate-based assay called CRAFTseq has been developed that uses ‘multi-omic’ single-cell RNA sequencing and direct genotyping of CRISPR edits to test the functional effects of genetic variants o...
www.nature.com
July 23, 2025 at 11:34 PM
So excited to share our latest study on defining the function of disease variants by editing single cells, and assuming them with CRAFT-seq! Special thanks to @zpmu.bsky.social and @baglaenkolab.bsky.social! @broadinstitute.org
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Inmaculada Rodriguez-Martin
🚀Join us on our #EULAR and #EMEUNET Webinar: "Gender-specific differences in rheumatic diseases"
💻Wednesday, 13 Aug 2025, 18:00-18:45 CEST
Register here👉https://pulse.ly/m5gtytw87m
#eularEMEUNET #Rheumatology
💻Wednesday, 13 Aug 2025, 18:00-18:45 CEST
Register here👉https://pulse.ly/m5gtytw87m
#eularEMEUNET #Rheumatology
July 14, 2025 at 8:00 AM
🚀Join us on our #EULAR and #EMEUNET Webinar: "Gender-specific differences in rheumatic diseases"
💻Wednesday, 13 Aug 2025, 18:00-18:45 CEST
Register here👉https://pulse.ly/m5gtytw87m
#eularEMEUNET #Rheumatology
💻Wednesday, 13 Aug 2025, 18:00-18:45 CEST
Register here👉https://pulse.ly/m5gtytw87m
#eularEMEUNET #Rheumatology
Reposted by Inmaculada Rodriguez-Martin
🎓 #Taller interactivo y foro de puesta en común por Eva Luna Díaz García, Investigadora en Antropología y Sociología en la Universidad Complutense de Madrid y profesora/colaboradora de @prismaciencia.bsky.social
'Diversidad LGTBIQA+ en Ciencia, Tecnología e Innovación'
🕛12h
📅 Viernes 27
📍 IPBLN
'Diversidad LGTBIQA+ en Ciencia, Tecnología e Innovación'
🕛12h
📅 Viernes 27
📍 IPBLN
June 23, 2025 at 12:42 PM
🎓 #Taller interactivo y foro de puesta en común por Eva Luna Díaz García, Investigadora en Antropología y Sociología en la Universidad Complutense de Madrid y profesora/colaboradora de @prismaciencia.bsky.social
'Diversidad LGTBIQA+ en Ciencia, Tecnología e Innovación'
🕛12h
📅 Viernes 27
📍 IPBLN
'Diversidad LGTBIQA+ en Ciencia, Tecnología e Innovación'
🕛12h
📅 Viernes 27
📍 IPBLN
Reposted by Inmaculada Rodriguez-Martin
@raungar.bsky.social, @sbmontgom.bsky.social, & co. examine the impact of rare variants & sex on gene expression across the X-chromosome & autosomes, identifying 700+ rare variants w/ predicted functional differences in males & females: www.cell.com/hgg-advances... #ASHG @hggadvances.bsky.social
June 12, 2025 at 3:53 PM
@raungar.bsky.social, @sbmontgom.bsky.social, & co. examine the impact of rare variants & sex on gene expression across the X-chromosome & autosomes, identifying 700+ rare variants w/ predicted functional differences in males & females: www.cell.com/hgg-advances... #ASHG @hggadvances.bsky.social
Reposted by Inmaculada Rodriguez-Martin
🎓 En el #WIPSeminar de hoy, Inma ha explicado los resultados preliminares de su investigación acerca del perfil genético con enfoque de sexo que revela la relevancia de IL12RB2 como un locus específico en mujeres en la #EsclerosisSistemica 🧬
June 10, 2025 at 9:35 AM
🎓 En el #WIPSeminar de hoy, Inma ha explicado los resultados preliminares de su investigación acerca del perfil genético con enfoque de sexo que revela la relevancia de IL12RB2 como un locus específico en mujeres en la #EsclerosisSistemica 🧬
Reposted by Inmaculada Rodriguez-Martin
Great presentation by my lab mate @inmaculadaroma.bsky.social ✨
Sex-aware science is something to stand strong for ✊
Sex-aware science is something to stand strong for ✊
🎓 En el #WIPSeminar de hoy, Inma ha explicado los resultados preliminares de su investigación acerca del perfil genético con enfoque de sexo que revela la relevancia de IL12RB2 como un locus específico en mujeres en la #EsclerosisSistemica 🧬
June 10, 2025 at 10:07 AM
Great presentation by my lab mate @inmaculadaroma.bsky.social ✨
Sex-aware science is something to stand strong for ✊
Sex-aware science is something to stand strong for ✊
Thank you so much! 🙏 I really appreciate your kind words and support. And big thanks to everyone who came to the talk and engaged with such thoughtful questions!
Grateful to be in a lab that values rigorous, sex-aware science. Let’s keep pushing for better, more inclusive research! 💪✨
Grateful to be in a lab that values rigorous, sex-aware science. Let’s keep pushing for better, more inclusive research! 💪✨
Great presentation by my lab mate @inmaculadaroma.bsky.social ✨
Sex-aware science is something to stand strong for ✊
Sex-aware science is something to stand strong for ✊
🎓 En el #WIPSeminar de hoy, Inma ha explicado los resultados preliminares de su investigación acerca del perfil genético con enfoque de sexo que revela la relevancia de IL12RB2 como un locus específico en mujeres en la #EsclerosisSistemica 🧬
June 10, 2025 at 12:03 PM
Thank you so much! 🙏 I really appreciate your kind words and support. And big thanks to everyone who came to the talk and engaged with such thoughtful questions!
Grateful to be in a lab that values rigorous, sex-aware science. Let’s keep pushing for better, more inclusive research! 💪✨
Grateful to be in a lab that values rigorous, sex-aware science. Let’s keep pushing for better, more inclusive research! 💪✨
Reposted by Inmaculada Rodriguez-Martin
One thing still missing in many GWAS pipelines: chrX analysis... In this study from @ajhgnews.bsky.social, Mefford et al. explore X-GWAS across 48 UKBB traits and as expected, ~3% of trait heritability comes from chrX.
Looks like it’s time we start doing this! www.cell.com/ajhg/fulltex...
Looks like it’s time we start doing this! www.cell.com/ajhg/fulltex...
Role of X chromosome and dosage-compensation mechanisms in complex trait genetics
We show that the X chromosome, understudied in genome-wide association studies, contributes
to complex traits in a manner shaped by dosage-compensation mechanisms. We find near-full
X inactivation bal...
www.cell.com
June 6, 2025 at 9:32 AM
One thing still missing in many GWAS pipelines: chrX analysis... In this study from @ajhgnews.bsky.social, Mefford et al. explore X-GWAS across 48 UKBB traits and as expected, ~3% of trait heritability comes from chrX.
Looks like it’s time we start doing this! www.cell.com/ajhg/fulltex...
Looks like it’s time we start doing this! www.cell.com/ajhg/fulltex...
Reposted by Inmaculada Rodriguez-Martin
Excited to share that our abstract for #EULAR was selected as one of the Top 10 Abstracts at EULAR 2025 by EMEUNET! 🙌🥰
Huge thanks to the committee, I’m truly honored!
Hope to see you in Barcelona! #EMEUNET #EULAR2025
Huge thanks to the committee, I’m truly honored!
Hope to see you in Barcelona! #EMEUNET #EULAR2025
May 28, 2025 at 3:13 PM
Excited to share that our abstract for #EULAR was selected as one of the Top 10 Abstracts at EULAR 2025 by EMEUNET! 🙌🥰
Huge thanks to the committee, I’m truly honored!
Hope to see you in Barcelona! #EMEUNET #EULAR2025
Huge thanks to the committee, I’m truly honored!
Hope to see you in Barcelona! #EMEUNET #EULAR2025