Laurent LE
@laurent-le.bsky.social
PhD in Biophotonics 🔬. Post-Doc in Lévêque-Fort team. Fluorescence Microscopy, FLIM, SMLM, Multiplexing.
Reposted by Laurent LE
Brightness demixing: a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on brightness. @slfort.bsky.social @laurent-le.bsky.social @ismolab.bsky.social @instlangevin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy - Nature Methods
Brightness demixing is a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on their brightness rather than their spectral properties. As this ...
www.nature.com
June 11, 2026 at 5:50 PM
Brightness demixing: a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on brightness. @slfort.bsky.social @laurent-le.bsky.social @ismolab.bsky.social @instlangevin.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Laurent LE
New paper alert!
Le et al. introduce brightness demixing, a method that distinguishes fluorophores by their photon flux rather than spectral properties. Congrats!
Authors used our #DNAPAINT reagents to image clathrin, tubulin, vimentin, & nuclear pores.
🔗 www.nature.com/articles/s41...
Le et al. introduce brightness demixing, a method that distinguishes fluorophores by their photon flux rather than spectral properties. Congrats!
Authors used our #DNAPAINT reagents to image clathrin, tubulin, vimentin, & nuclear pores.
🔗 www.nature.com/articles/s41...
Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy - Nature Methods
Brightness demixing is a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on their brightness rather than their spectral properties. As this ...
www.nature.com
June 10, 2026 at 10:54 AM
New paper alert!
Le et al. introduce brightness demixing, a method that distinguishes fluorophores by their photon flux rather than spectral properties. Congrats!
Authors used our #DNAPAINT reagents to image clathrin, tubulin, vimentin, & nuclear pores.
🔗 www.nature.com/articles/s41...
Le et al. introduce brightness demixing, a method that distinguishes fluorophores by their photon flux rather than spectral properties. Congrats!
Authors used our #DNAPAINT reagents to image clathrin, tubulin, vimentin, & nuclear pores.
🔗 www.nature.com/articles/s41...
Reposted by Laurent LE
Big thanks to Andrea Bucci and @laurent-le.bsky.social for the 13h drive with a microscope in the trunk...and setting it up!
First workshop #MifoBio2025 done, challenge won.
A #SPADarray in any laser-scanning microscope.
@genoainstruments.bsky.social @iitalk.bsky.social @gdrimabio.bsky.social
First workshop #MifoBio2025 done, challenge won.
A #SPADarray in any laser-scanning microscope.
@genoainstruments.bsky.social @iitalk.bsky.social @gdrimabio.bsky.social
October 13, 2025 at 3:13 PM
Big thanks to Andrea Bucci and @laurent-le.bsky.social for the 13h drive with a microscope in the trunk...and setting it up!
First workshop #MifoBio2025 done, challenge won.
A #SPADarray in any laser-scanning microscope.
@genoainstruments.bsky.social @iitalk.bsky.social @gdrimabio.bsky.social
First workshop #MifoBio2025 done, challenge won.
A #SPADarray in any laser-scanning microscope.
@genoainstruments.bsky.social @iitalk.bsky.social @gdrimabio.bsky.social
Reposted by Laurent LE
Time for the second #MifoBio2025 workshop with @laurent-le.bsky.social and Andrea Bucci on building a #fluorescencelifetime #imagescanningmicroscopy system. Thanks @erc.europa.eu, @iitalk.bsky.social and @genoainstruments.bsky.social
#SPADarray #BrightEyes_ERC #photonresolvedmicroscopy
#SPADarray #BrightEyes_ERC #photonresolvedmicroscopy
October 15, 2025 at 9:26 PM
Time for the second #MifoBio2025 workshop with @laurent-le.bsky.social and Andrea Bucci on building a #fluorescencelifetime #imagescanningmicroscopy system. Thanks @erc.europa.eu, @iitalk.bsky.social and @genoainstruments.bsky.social
#SPADarray #BrightEyes_ERC #photonresolvedmicroscopy
#SPADarray #BrightEyes_ERC #photonresolvedmicroscopy
Reposted by Laurent LE
🔬Happy to share our new preprint, where brightness is used to identify single molecule emission in 2D/3D, with a single camera ! Part of the PhD work of @laurent-le.bsky.social and Surabhi, great collaboration with @emmanuelfort.bsky.social from @instlangevin.bsky.social @ismolab.bsky.social #SMLM
March 4, 2025 at 8:58 AM
🔬Happy to share our new preprint, where brightness is used to identify single molecule emission in 2D/3D, with a single camera ! Part of the PhD work of @laurent-le.bsky.social and Surabhi, great collaboration with @emmanuelfort.bsky.social from @instlangevin.bsky.social @ismolab.bsky.social #SMLM
Reposted by Laurent LE
And last but not least Laurent Le from the team on part of his PhD work @ismolab.bsky.social
January 16, 2025 at 5:01 PM
And last but not least Laurent Le from the team on part of his PhD work @ismolab.bsky.social