Who said you can't get poetic in an article proposing a new SMLM localization algorithm? "The beauty of MLLM builds on the theoretical understanding of the information contained in a single detected photon"
Maximum Likelihood Localization Maps
Single-molecule localization microscopy commonly reconstructs images from estimated emitter coordinates. We calculate maximum-likelihood localization maps (MLLM), a non-iterative approach that evaluat...
www.biorxiv.org
November 9, 2026 at 9:19 AM
Who said you can't get poetic in an article proposing a new SMLM localization algorithm? "The beauty of MLLM builds on the theoretical understanding of the information contained in a single detected photon"
One platform, 5 modalities: #TIRF, #FRAP, #STORM, #DNAPAINT & #SPT 🔬 Up to 230×230 µm² FOV for whole-cell #SMLM.
Meet us at Booth #4, #GBI_EoE2026, EMBL Heidelberg, Oct 26–29.
Frank Drechsler will be on-site. We look forward to seeing you!
@globalbioimaging.bsky.social
#SMLM
Meet us at Booth #4, #GBI_EoE2026, EMBL Heidelberg, Oct 26–29.
Frank Drechsler will be on-site. We look forward to seeing you!
@globalbioimaging.bsky.social
#SMLM
October 21, 2026 at 2:15 PM
One platform, 5 modalities: #TIRF, #FRAP, #STORM, #DNAPAINT & #SPT 🔬 Up to 230×230 µm² FOV for whole-cell #SMLM.
Meet us at Booth #4, #GBI_EoE2026, EMBL Heidelberg, Oct 26–29.
Frank Drechsler will be on-site. We look forward to seeing you!
@globalbioimaging.bsky.social
#SMLM
Meet us at Booth #4, #GBI_EoE2026, EMBL Heidelberg, Oct 26–29.
Frank Drechsler will be on-site. We look forward to seeing you!
@globalbioimaging.bsky.social
#SMLM
Isn’t that the thing in Paris known for visualizing the SMLM approach?
October 19, 2026 at 7:30 PM
Isn’t that the thing in Paris known for visualizing the SMLM approach?
#SFBS2026: Time for @henriqueslab.bsky.social to blow our minds with the stunning suite of approaches his lab developed in less than 10 years: (e)SRRF, DL4Mic, SReD, NanoPyx, VLab4Mic. Starting with the legendary SMLM Eiffel tower! henriqueslab.org
October 19, 2026 at 8:40 AM
#SFBS2026: Time for @henriqueslab.bsky.social to blow our minds with the stunning suite of approaches his lab developed in less than 10 years: (e)SRRF, DL4Mic, SReD, NanoPyx, VLab4Mic. Starting with the legendary SMLM Eiffel tower! henriqueslab.org
🔬 New preprint alert 🔬
Authors introduce a method for fast 3D volumetric imaging of whole cells and tissues with DNA-PAINT for nanoscale resolution, no post-processing stitching required.
biorxiv.org/content/10.6...
Congratulations to all authors!
#MassivePhotonics #SMLM #Microscopy #DNAPAINT
Authors introduce a method for fast 3D volumetric imaging of whole cells and tissues with DNA-PAINT for nanoscale resolution, no post-processing stitching required.
biorxiv.org/content/10.6...
Congratulations to all authors!
#MassivePhotonics #SMLM #Microscopy #DNAPAINT
biorxiv.org
October 13, 2026 at 8:41 AM
🔬 New preprint alert 🔬
Authors introduce a method for fast 3D volumetric imaging of whole cells and tissues with DNA-PAINT for nanoscale resolution, no post-processing stitching required.
biorxiv.org/content/10.6...
Congratulations to all authors!
#MassivePhotonics #SMLM #Microscopy #DNAPAINT
Authors introduce a method for fast 3D volumetric imaging of whole cells and tissues with DNA-PAINT for nanoscale resolution, no post-processing stitching required.
biorxiv.org/content/10.6...
Congratulations to all authors!
#MassivePhotonics #SMLM #Microscopy #DNAPAINT
Btw dia baru lps accident sec day dia belanja air tu. Masa first day dia belanja tu, mmg aku tknk pndg dia (sbb dia sombong dgn aku smlm, so aku nk bls blik) And aku rasa dia mmg pndg aku pun mse dia bg adik dia air tu. But aku nebes, acah2 msuk bilik.
October 10, 2026 at 5:14 PM
Btw dia baru lps accident sec day dia belanja air tu. Masa first day dia belanja tu, mmg aku tknk pndg dia (sbb dia sombong dgn aku smlm, so aku nk bls blik) And aku rasa dia mmg pndg aku pun mse dia bg adik dia air tu. But aku nebes, acah2 msuk bilik.
How to make imaging faster, sharper, easier?
It turns out "self-blinking dyes" - which can switch between bright and dark states on their own - can take super-resolution microscopy to the next level: www.uni-goettingen.de/en/3240.html...
Research in #NanoLetters: doi.org/10.1021/acs....
It turns out "self-blinking dyes" - which can switch between bright and dark states on their own - can take super-resolution microscopy to the next level: www.uni-goettingen.de/en/3240.html...
Research in #NanoLetters: doi.org/10.1021/acs....
October 8, 2026 at 9:37 AM
How to make imaging faster, sharper, easier?
It turns out "self-blinking dyes" - which can switch between bright and dark states on their own - can take super-resolution microscopy to the next level: www.uni-goettingen.de/en/3240.html...
Research in #NanoLetters: doi.org/10.1021/acs....
It turns out "self-blinking dyes" - which can switch between bright and dark states on their own - can take super-resolution microscopy to the next level: www.uni-goettingen.de/en/3240.html...
Research in #NanoLetters: doi.org/10.1021/acs....
"C'est inutile" : à Villefontaine, des profs venus soutenir leurs élèves et refuser les temps de "démocratie interne"
➡️ https://l.ici.fr/Smlm
➡️ https://l.ici.fr/Smlm
October 8, 2026 at 12:15 PM
"C'est inutile" : à Villefontaine, des profs venus soutenir leurs élèves et refuser les temps de "démocratie interne"
➡️ https://l.ici.fr/Smlm
➡️ https://l.ici.fr/Smlm
Yoohoo, more 3D SMLM! @chenjiajiachen.bsky.social
Pls try BigVolumeBrowser for point cloud data rendering, it can even deskew it
Pls try BigVolumeBrowser for point cloud data rendering, it can even deskew it
October 7, 2026 at 8:07 AM
Yoohoo, more 3D SMLM! @chenjiajiachen.bsky.social
Pls try BigVolumeBrowser for point cloud data rendering, it can even deskew it
Pls try BigVolumeBrowser for point cloud data rendering, it can even deskew it
Fresh preprint from St Johnston lab in collaboration with Paluch lab. "Fast, 3D SMLM imaging modality, Intrinsic3D, which combines the speed and optical sectioning of oblique plane microscopy (OPM) with the nanometre resolution of SMLM using DNAPAINT".
Amazing imaging, here is one of my favourite:
Amazing imaging, here is one of my favourite:
October 6, 2026 at 6:16 AM
Fresh preprint from St Johnston lab in collaboration with Paluch lab. "Fast, 3D SMLM imaging modality, Intrinsic3D, which combines the speed and optical sectioning of oblique plane microscopy (OPM) with the nanometre resolution of SMLM using DNAPAINT".
Amazing imaging, here is one of my favourite:
Amazing imaging, here is one of my favourite:
Cyclisme - L'Etoile de Bessèges, Tour du Gard, le détail des 5 étapes en 2027, ICI :
➡️ https://l.ici.fr/SmlM
➡️ https://l.ici.fr/SmlM
October 5, 2026 at 7:01 PM
Cyclisme - L'Etoile de Bessèges, Tour du Gard, le détail des 5 étapes en 2027, ICI :
➡️ https://l.ici.fr/SmlM
➡️ https://l.ici.fr/SmlM
We’re exhibiting at #𝗦𝗣𝗔𝗢𝗠𝟮𝟬𝟮𝟲, 6–9 Oct at El Sucre (Vic).
Come & discuss:
🔹 SMLM at ~10–20 nm
🔹 Multicolor & 3D imaging
🔹 Sample prep & buffers
🔹 Quantitative analysis with NEO
🎁 Visit our booth for a chance to win a free Abbelight Smart Buffer Kit!
#SMLM #SuperResolution #Microscopy #Nanoscopy
Come & discuss:
🔹 SMLM at ~10–20 nm
🔹 Multicolor & 3D imaging
🔹 Sample prep & buffers
🔹 Quantitative analysis with NEO
🎁 Visit our booth for a chance to win a free Abbelight Smart Buffer Kit!
#SMLM #SuperResolution #Microscopy #Nanoscopy
October 1, 2026 at 3:22 PM
We’re exhibiting at #𝗦𝗣𝗔𝗢𝗠𝟮𝟬𝟮𝟲, 6–9 Oct at El Sucre (Vic).
Come & discuss:
🔹 SMLM at ~10–20 nm
🔹 Multicolor & 3D imaging
🔹 Sample prep & buffers
🔹 Quantitative analysis with NEO
🎁 Visit our booth for a chance to win a free Abbelight Smart Buffer Kit!
#SMLM #SuperResolution #Microscopy #Nanoscopy
Come & discuss:
🔹 SMLM at ~10–20 nm
🔹 Multicolor & 3D imaging
🔹 Sample prep & buffers
🔹 Quantitative analysis with NEO
🎁 Visit our booth for a chance to win a free Abbelight Smart Buffer Kit!
#SMLM #SuperResolution #Microscopy #Nanoscopy
Nice! We found a lossy re-quantization super useful for SMLM. If you know someone desperate for a Python-exposed C variant with some (experimental) Zarr in advance of your implementation, we have one in PYME. Some performance benchmarked in doi.org/10.1038/s415...
September 30, 2026 at 2:45 AM
Nice! We found a lossy re-quantization super useful for SMLM. If you know someone desperate for a Python-exposed C variant with some (experimental) Zarr in advance of your implementation, we have one in PYME. Some performance benchmarked in doi.org/10.1038/s415...
🔬 See you in Marburg!
We are exhibiting at the 6th VAAM Microbial Cell Biology meeting, 5–7 Oct 2026.
Catch Frank Drechsler's talk Tue 6 Oct, 14:00, then visit our booth to see how SMLM resolves bacterial nanostructures at ~10–20 nm.
#Microbiology #SMLM #VAAM
We are exhibiting at the 6th VAAM Microbial Cell Biology meeting, 5–7 Oct 2026.
Catch Frank Drechsler's talk Tue 6 Oct, 14:00, then visit our booth to see how SMLM resolves bacterial nanostructures at ~10–20 nm.
#Microbiology #SMLM #VAAM
September 29, 2026 at 1:14 PM
🔬 See you in Marburg!
We are exhibiting at the 6th VAAM Microbial Cell Biology meeting, 5–7 Oct 2026.
Catch Frank Drechsler's talk Tue 6 Oct, 14:00, then visit our booth to see how SMLM resolves bacterial nanostructures at ~10–20 nm.
#Microbiology #SMLM #VAAM
We are exhibiting at the 6th VAAM Microbial Cell Biology meeting, 5–7 Oct 2026.
Catch Frank Drechsler's talk Tue 6 Oct, 14:00, then visit our booth to see how SMLM resolves bacterial nanostructures at ~10–20 nm.
#Microbiology #SMLM #VAAM
Spontaneous blinking. OneStep IF. Precise #SMLM. 🙌
Our Smart Secondaries® JF635b combine a self-blinking dye with small secondary #nanobodies for reduced linkage error, no clustering & fast OneStep IF.
For #dSTORM & #MINFLUX 🔬✨
🦙 Browse our JF635b-conjugated nanobodies here: bit.ly/4ffIkdB
Our Smart Secondaries® JF635b combine a self-blinking dye with small secondary #nanobodies for reduced linkage error, no clustering & fast OneStep IF.
For #dSTORM & #MINFLUX 🔬✨
🦙 Browse our JF635b-conjugated nanobodies here: bit.ly/4ffIkdB
September 28, 2026 at 2:43 PM
Spontaneous blinking. OneStep IF. Precise #SMLM. 🙌
Our Smart Secondaries® JF635b combine a self-blinking dye with small secondary #nanobodies for reduced linkage error, no clustering & fast OneStep IF.
For #dSTORM & #MINFLUX 🔬✨
🦙 Browse our JF635b-conjugated nanobodies here: bit.ly/4ffIkdB
Our Smart Secondaries® JF635b combine a self-blinking dye with small secondary #nanobodies for reduced linkage error, no clustering & fast OneStep IF.
For #dSTORM & #MINFLUX 🔬✨
🦙 Browse our JF635b-conjugated nanobodies here: bit.ly/4ffIkdB
Act, aku dah lama tk stalk dia. Aku rasa beberapa hri sblum aku stalk dia smlm, dia masih lg public acc. Tiba2 smlm aku search nama dia, ehhhh dah PRIVATE?! WHY?! Tak dapat dh la aku stalk dia dri luar. Nak jgk aku tgk dia post ape je. Tp dh private ni nak stalk ape je?!
September 25, 2026 at 9:35 AM
Act, aku dah lama tk stalk dia. Aku rasa beberapa hri sblum aku stalk dia smlm, dia masih lg public acc. Tiba2 smlm aku search nama dia, ehhhh dah PRIVATE?! WHY?! Tak dapat dh la aku stalk dia dri luar. Nak jgk aku tgk dia post ape je. Tp dh private ni nak stalk ape je?!
Kisah dia, tkde mende pun jdi, no interaction sgt dgn dia, last jumpa dia mse dia bg phone utk buat content dkt atilla tu jela. Cumanya, smlm aku nak stalk dia. Mcm biasa la aku cuma nak tgk post dia dri luar je. Tk bkk pun profile dia.
September 25, 2026 at 9:33 AM
Kisah dia, tkde mende pun jdi, no interaction sgt dgn dia, last jumpa dia mse dia bg phone utk buat content dkt atilla tu jela. Cumanya, smlm aku nak stalk dia. Mcm biasa la aku cuma nak tgk post dia dri luar je. Tk bkk pun profile dia.
@loicaroyer.bsky.social and pity there is no SMLM data in the showreel. This microscopy branch was splatting Gaussians before splatting became popular.:)
September 23, 2026 at 12:16 PM
@loicaroyer.bsky.social and pity there is no SMLM data in the showreel. This microscopy branch was splatting Gaussians before splatting became popular.:)
Beneran bro udah bnyak cew² yg make bsky dri Ind? Wajar sih blm keliatan, soalnya br smlm bikin akun... Kangen twitter klasik ceritanya ne smlm ampe nanya gemini soal platform yg mirip twitklasik ada apa nggak, akhirnya di saranin & coba bsky.
September 21, 2026 at 4:51 AM
Beneran bro udah bnyak cew² yg make bsky dri Ind? Wajar sih blm keliatan, soalnya br smlm bikin akun... Kangen twitter klasik ceritanya ne smlm ampe nanya gemini soal platform yg mirip twitklasik ada apa nggak, akhirnya di saranin & coba bsky.
The review in PhotoniX Life summarizes two decades of progress in SMLM drift correction, providing a practical framework for researchers to select the best strategy for their experimental needs.
👉 www.eurekalert.org/news-release...
（DOI: 10.3724/PXLIFE.2025-0018）
👉 www.eurekalert.org/news-release...
（DOI: 10.3724/PXLIFE.2025-0018）
Drift correction methods for minimizing motion artifacts in single-molecule localization microscopy
PhotoniX Life published a review that summarizes advancements in drift correction over the past 20 years for single-molecule localization microscopy. The study categorizes four major technical routes ...
www.eurekalert.org
September 11, 2026 at 9:45 AM
The review in PhotoniX Life summarizes two decades of progress in SMLM drift correction, providing a practical framework for researchers to select the best strategy for their experimental needs.
👉 www.eurekalert.org/news-release...
（DOI: 10.3724/PXLIFE.2025-0018）
👉 www.eurekalert.org/news-release...
（DOI: 10.3724/PXLIFE.2025-0018）
🔬 Join us for the webinar: Towards Molecular Spatial Omics, with Dr. Florian Schueder (EPFL).
Topics include DNA-PAINT, high-throughput imaging & spectrally unlimited multiplexing.
🗓️ 12 Oct, 15:00
👉 Register: us06web.zoom.us/webinar/regi...
#SMLM #DNAPAINT #Microscopy
Topics include DNA-PAINT, high-throughput imaging & spectrally unlimited multiplexing.
🗓️ 12 Oct, 15:00
👉 Register: us06web.zoom.us/webinar/regi...
#SMLM #DNAPAINT #Microscopy
September 10, 2026 at 1:38 PM
🔬 Join us for the webinar: Towards Molecular Spatial Omics, with Dr. Florian Schueder (EPFL).
Topics include DNA-PAINT, high-throughput imaging & spectrally unlimited multiplexing.
🗓️ 12 Oct, 15:00
👉 Register: us06web.zoom.us/webinar/regi...
#SMLM #DNAPAINT #Microscopy
Topics include DNA-PAINT, high-throughput imaging & spectrally unlimited multiplexing.
🗓️ 12 Oct, 15:00
👉 Register: us06web.zoom.us/webinar/regi...
#SMLM #DNAPAINT #Microscopy
New publication alert 🚨 Our Nano Letters paper on self-blinking dyes with nanobodies for robust SMLM is now Open Access!
pubs.acs.org/nalefd/artic...
Commercial Nb–JF635b probes are available from @nanotag.bsky.social.
Joint effort of amazing collaborators, inspired by the great @opazo.bsky.social
pubs.acs.org/nalefd/artic...
Commercial Nb–JF635b probes are available from @nanotag.bsky.social.
Joint effort of amazing collaborators, inspired by the great @opazo.bsky.social
August 27, 2026 at 1:19 PM
New publication alert 🚨 Our Nano Letters paper on self-blinking dyes with nanobodies for robust SMLM is now Open Access!
pubs.acs.org/nalefd/artic...
Commercial Nb–JF635b probes are available from @nanotag.bsky.social.
Joint effort of amazing collaborators, inspired by the great @opazo.bsky.social
pubs.acs.org/nalefd/artic...
Commercial Nb–JF635b probes are available from @nanotag.bsky.social.
Joint effort of amazing collaborators, inspired by the great @opazo.bsky.social
The first paper of my PhD is now out in The Journal of Membrane Biology! 🎉
We used DNA-PAINT SMLM to investigate the role of glycosylation in membrane protein clustering.
Thanks to all co-authors and my supervisor Hjalmar Brismar for making it possible!
Check out the paper: shorturl.at/Wb8Y9
We used DNA-PAINT SMLM to investigate the role of glycosylation in membrane protein clustering.
Thanks to all co-authors and my supervisor Hjalmar Brismar for making it possible!
Check out the paper: shorturl.at/Wb8Y9
August 27, 2026 at 12:36 PM
The first paper of my PhD is now out in The Journal of Membrane Biology! 🎉
We used DNA-PAINT SMLM to investigate the role of glycosylation in membrane protein clustering.
Thanks to all co-authors and my supervisor Hjalmar Brismar for making it possible!
Check out the paper: shorturl.at/Wb8Y9
We used DNA-PAINT SMLM to investigate the role of glycosylation in membrane protein clustering.
Thanks to all co-authors and my supervisor Hjalmar Brismar for making it possible!
Check out the paper: shorturl.at/Wb8Y9
(LinkedIn cross post) 0.11.3 of #webSMLM released. Since 0.11.0 we added: headless spectral SMLM runs, *.ND2 loading, single particle tracking (sptPALM, Nile red PAINT, etc), light (see below), dark or high contrast mode; *.svg export of plots, change to MIT license,... (1/2)
August 21, 2026 at 7:40 AM
(LinkedIn cross post) 0.11.3 of #webSMLM released. Since 0.11.0 we added: headless spectral SMLM runs, *.ND2 loading, single particle tracking (sptPALM, Nile red PAINT, etc), light (see below), dark or high contrast mode; *.svg export of plots, change to MIT license,... (1/2)