AI in Microscopy: A BioImaging Guide (bioimagingai.janelia.org) is available now! This free, online textbook bridges the gap between tool developers & microscopists + biologists. Whether you’re new to AI or already using it, we hope this book gives you the confidence to apply AI in your research.
AI in Microscopy: A BioImaging Guide
bioimagingai.janelia.org
October 27, 2026 at 5:19 PM
AI in Microscopy: A BioImaging Guide (bioimagingai.janelia.org) is available now! This free, online textbook bridges the gap between tool developers & microscopists + biologists. Whether you’re new to AI or already using it, we hope this book gives you the confidence to apply AI in your research.
October 27, 2026 at 3:42 PM
October 28, 2026 at 9:31 AM
Gorgeous microscopy!
We found that cells survive a proteostasis defect, but not the lipid imbalance it causes. Rer1 & the Dsc complex triage orphan membrane proteins at the Golgi. Lose both & DAG-rich multilamellar compartments (DMCs) form. Drain DAG & cellular architecture recovers.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
October 27, 2026 at 11:09 AM
Gorgeous microscopy!
This is what we do at @bic-bordeaux.bsky.social The most beautiful microscopy developments in neurosciences. Super-resolution in brain tissue...
Check this out!
www.biorxiv.org/content/10.6...
Check this out!
www.biorxiv.org/content/10.6...
October 28, 2026 at 12:00 AM
This is what we do at @bic-bordeaux.bsky.social The most beautiful microscopy developments in neurosciences. Super-resolution in brain tissue...
Check this out!
www.biorxiv.org/content/10.6...
Check this out!
www.biorxiv.org/content/10.6...
AI is rapidly transforming microscopy, but as microscopist or biologist, it can be hard to know where to start! I am pleased to share the free, online textbook that @scopeshifu.bsky.social, @owfpuls.bsky.social, and I edited to address this. Check it out at bioimagingai.janelia.org (1/11)
October 28, 2026 at 1:03 PM
AI is rapidly transforming microscopy, but as microscopist or biologist, it can be hard to know where to start! I am pleased to share the free, online textbook that @scopeshifu.bsky.social, @owfpuls.bsky.social, and I edited to address this. Check it out at bioimagingai.janelia.org (1/11)
Checkout our new preprint 🔬! An eye-opening analysis detailing the adoption of bioimage-analysis tools in microscopy, curated with Bruno Saraiva and @henriqueslab.bsky.social – a thread 🧵:
preprint: doi.org/10.64898/2026.10.21.760457
github: github.com/HenriquesLab/mapping-bioimage-software
preprint: doi.org/10.64898/2026.10.21.760457
github: github.com/HenriquesLab/mapping-bioimage-software
October 27, 2026 at 9:12 AM
Checkout our new preprint 🔬! An eye-opening analysis detailing the adoption of bioimage-analysis tools in microscopy, curated with Bruno Saraiva and @henriqueslab.bsky.social – a thread 🧵:
preprint: doi.org/10.64898/2026.10.21.760457
github: github.com/HenriquesLab/mapping-bioimage-software
preprint: doi.org/10.64898/2026.10.21.760457
github: github.com/HenriquesLab/mapping-bioimage-software
I've been steadily developing our image compression software over the past month and now you can try it out in your browser, without needing to install anything, thanks to the magic of WebAssembly!
beryl.mrc-lmb.cam.ac.uk/radelta/
No data is uploaded anywhere, it all stays on your computer.
beryl.mrc-lmb.cam.ac.uk/radelta/
No data is uploaded anywhere, it all stays on your computer.
October 27, 2026 at 6:53 PM
I've been steadily developing our image compression software over the past month and now you can try it out in your browser, without needing to install anything, thanks to the magic of WebAssembly!
beryl.mrc-lmb.cam.ac.uk/radelta/
No data is uploaded anywhere, it all stays on your computer.
beryl.mrc-lmb.cam.ac.uk/radelta/
No data is uploaded anywhere, it all stays on your computer.
...corresponding GitHub Repos:
Strobe-enhanced microscopy stage:
github.com/wenzel-lab/s...
Syringe pump & controller:
github.com/wenzel-lab/s...
Rio microfluidics controller:
github.com/wenzel-lab/r...
Strobe-enhanced microscopy stage:
github.com/wenzel-lab/s...
Syringe pump & controller:
github.com/wenzel-lab/s...
Rio microfluidics controller:
github.com/wenzel-lab/r...
GitHub - wenzel-lab/strobe-enhanced-microscopy-stage: Strobe-Enhanced Microscopy Stage
Strobe-Enhanced Microscopy Stage. Contribute to wenzel-lab/strobe-enhanced-microscopy-stage development by creating an account on GitHub.
github.com
October 28, 2026 at 3:49 PM
...corresponding GitHub Repos:
Strobe-enhanced microscopy stage:
github.com/wenzel-lab/s...
Syringe pump & controller:
github.com/wenzel-lab/s...
Rio microfluidics controller:
github.com/wenzel-lab/r...
Strobe-enhanced microscopy stage:
github.com/wenzel-lab/s...
Syringe pump & controller:
github.com/wenzel-lab/s...
Rio microfluidics controller:
github.com/wenzel-lab/r...
🎉 New preprint! We built a fully open-source, 3D-printable droplet microfluidics platform with strobe-enhanced microscopy — sharp images of fast-moving droplets without a high-speed camera. All files on GitHub.
#Microfluidics #OpenHardware
🔗 biorxiv.org/content/10.64898/2026.10.19.758223v1
#Microfluidics #OpenHardware
🔗 biorxiv.org/content/10.64898/2026.10.19.758223v1
October 26, 2026 at 6:45 PM
🎉 New preprint! We built a fully open-source, 3D-printable droplet microfluidics platform with strobe-enhanced microscopy — sharp images of fast-moving droplets without a high-speed camera. All files on GitHub.
#Microfluidics #OpenHardware
🔗 biorxiv.org/content/10.64898/2026.10.19.758223v1
#Microfluidics #OpenHardware
🔗 biorxiv.org/content/10.64898/2026.10.19.758223v1
ImageJ usage in microscopy soars above other image analysis tools, and official citations fail to reflect its implementation (3/5)
October 27, 2026 at 9:12 AM
ImageJ usage in microscopy soars above other image analysis tools, and official citations fail to reflect its implementation (3/5)
New zine for my microscopy aficionados! Available at the Non-Fiction Comics Fest in Burlington, VT on Nov 14, 2026!
#zine #DIYzine #microscopy #Gowanus #meiofauna #meiobenthic #zines #burlington #nfcf
#zine #DIYzine #microscopy #Gowanus #meiofauna #meiobenthic #zines #burlington #nfcf
October 27, 2026 at 12:50 AM
New zine for my microscopy aficionados! Available at the Non-Fiction Comics Fest in Burlington, VT on Nov 14, 2026!
#zine #DIYzine #microscopy #Gowanus #meiofauna #meiobenthic #zines #burlington #nfcf
#zine #DIYzine #microscopy #Gowanus #meiofauna #meiobenthic #zines #burlington #nfcf
🔬📈 We analysed #microscopy papers to track #bioimage analysis use. ImageJ+Fiji dominate, but others are gaining ground. Researchers undercite them and provide too little detail to reproduce analyses. By Tayla and Bruno, with @guijacquemet.bsky.social lab
📄 doi.org/10.64898/2026.10.21.760457
📄 doi.org/10.64898/2026.10.21.760457
October 27, 2026 at 2:17 PM
🔬📈 We analysed #microscopy papers to track #bioimage analysis use. ImageJ+Fiji dominate, but others are gaining ground. Researchers undercite them and provide too little detail to reproduce analyses. By Tayla and Bruno, with @guijacquemet.bsky.social lab
📄 doi.org/10.64898/2026.10.21.760457
📄 doi.org/10.64898/2026.10.21.760457
Multi-immersion oblique plane microscopy: a flexible light-sheet microscope for imaging a range of biological sample types. @retof.bsky.social @amsikking.bsky.social @kevin-dean.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multi-immersion oblique plane microscope (miOPM): a reconfigurable platform for high-resolution light-sheet fluorescence microscopy - Nature Methods
The multi-immersion oblique plane microscope is a flexible and versatile light-sheet microscope that allows imaging of samples ranging from cells in culture to whole organisms or cleared tissue sample...
www.nature.com
October 28, 2026 at 6:17 PM
Multi-immersion oblique plane microscopy: a flexible light-sheet microscope for imaging a range of biological sample types. @retof.bsky.social @amsikking.bsky.social @kevin-dean.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Sole scale, magnified 25 times (1887–88) by Marinus Pieter Filbri.
Source: @rijksmuseum.bsky.social
https://pdimagearchive.org/images/7e4bf712-c681-461b-ab33-4e7f59e10299
#micrography #micrographia #scales #fish #photomicrography #marinebiology #photography #art #publicdomain
Source: @rijksmuseum.bsky.social
https://pdimagearchive.org/images/7e4bf712-c681-461b-ab33-4e7f59e10299
#micrography #micrographia #scales #fish #photomicrography #marinebiology #photography #art #publicdomain
October 27, 2026 at 2:32 PM
Sole scale, magnified 25 times (1887–88) by Marinus Pieter Filbri.
Source: @rijksmuseum.bsky.social
https://pdimagearchive.org/images/7e4bf712-c681-461b-ab33-4e7f59e10299
#micrography #micrographia #scales #fish #photomicrography #marinebiology #photography #art #publicdomain
Source: @rijksmuseum.bsky.social
https://pdimagearchive.org/images/7e4bf712-c681-461b-ab33-4e7f59e10299
#micrography #micrographia #scales #fish #photomicrography #marinebiology #photography #art #publicdomain
MICROSCOPY.
Making the invisible visible since 1590.
(Yes, those little white balls are actually immune cells circulating through the tinniest blood vessels! Imaged non-invasively through the skin. Blood cells flow from your arterioles to your venules. Watch venous return at the capillary tip!!!)
Making the invisible visible since 1590.
(Yes, those little white balls are actually immune cells circulating through the tinniest blood vessels! Imaged non-invasively through the skin. Blood cells flow from your arterioles to your venules. Watch venous return at the capillary tip!!!)
October 24, 2026 at 4:13 PM
MICROSCOPY.
Making the invisible visible since 1590.
(Yes, those little white balls are actually immune cells circulating through the tinniest blood vessels! Imaged non-invasively through the skin. Blood cells flow from your arterioles to your venules. Watch venous return at the capillary tip!!!)
Making the invisible visible since 1590.
(Yes, those little white balls are actually immune cells circulating through the tinniest blood vessels! Imaged non-invasively through the skin. Blood cells flow from your arterioles to your venules. Watch venous return at the capillary tip!!!)
What if essentiality arose not from a single indispensable activity but rather from the iterative process of evolution arranging physiology around available resources?
October 26, 2026 at 10:35 PM
What if essentiality arose not from a single indispensable activity but rather from the iterative process of evolution arranging physiology around available resources?
Interesting new method: network fixation expansion microscopy (nfExM). Uses MeOH/acrolein at -20°C followed by gel embedding also at -20°C. Works well for microtubules, not sure about the mitochondria/Golgi morphology in the figure's examples www.biorxiv.org/content/10.6...
October 26, 2026 at 10:39 AM
Interesting new method: network fixation expansion microscopy (nfExM). Uses MeOH/acrolein at -20°C followed by gel embedding also at -20°C. Works well for microtubules, not sure about the mitochondria/Golgi morphology in the figure's examples www.biorxiv.org/content/10.6...
Blender tissue cartography: An intuitive tool for analyzing 3D microscopy data
#Drosophila
#Drosophila
Blender tissue cartography: An intuitive tool for analyzing 3D microscopy data
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
October 26, 2026 at 4:23 PM
Blender tissue cartography: An intuitive tool for analyzing 3D microscopy data
#Drosophila
#Drosophila
A 3D-printed mirror small enough to fit inside a sample chamber could make light sheet microscopy easier for more labs. Here’s how it works:
buff.ly/t0iRAsJ
buff.ly/t0iRAsJ
3D-Printed Mirror Improves Light Sheet Microscopy
Researchers at Rice University developed a new method that enables single-objective light sheet microscopy in standard, commercially available sample chambers.
buff.ly
October 28, 2026 at 4:42 PM
A 3D-printed mirror small enough to fit inside a sample chamber could make light sheet microscopy easier for more labs. Here’s how it works:
buff.ly/t0iRAsJ
buff.ly/t0iRAsJ
In @natmethods.nature.com: Researchers in Rockefeller's Vaziri lab have redesigned an entire imaging system from the ground up to develop a new microscopy platform that enables imaging of neuronal activity at single-cell resolution at unprecedented tissue depth.
🔗: https://bit.ly/48kiCDk
🔗: https://bit.ly/48kiCDk
October 28, 2026 at 4:07 PM
In @natmethods.nature.com: Researchers in Rockefeller's Vaziri lab have redesigned an entire imaging system from the ground up to develop a new microscopy platform that enables imaging of neuronal activity at single-cell resolution at unprecedented tissue depth.
🔗: https://bit.ly/48kiCDk
🔗: https://bit.ly/48kiCDk
The iMicro XL15 takes a slightly different approach to smartphone microscopy.
Pocket microscope backs away to show more of what you want to see
The iMicro XL15 takes a slightly different approach to smartphone microscopy. Built by the team behind the iMicro Q3p we covered in 2024, it weighs just 1.2 g (0.04 oz) but makes a very deliberate move...
newatlas.com
October 27, 2026 at 1:10 PM
The iMicro XL15 takes a slightly different approach to smartphone microscopy.
Microscope Lounge | Calm Motion, Deep Focus
#MicroscopeLounge #Microscopy #MicroWorlds #HiddenWorlds #SlowScience #AmbientVisuals #NatureCloseUp #RelaxingVisuals
#MicroscopeLounge #Microscopy #MicroWorlds #HiddenWorlds #SlowScience #AmbientVisuals #NatureCloseUp #RelaxingVisuals
October 27, 2026 at 3:31 PM
Microscope Lounge | Calm Motion, Deep Focus
#MicroscopeLounge #Microscopy #MicroWorlds #HiddenWorlds #SlowScience #AmbientVisuals #NatureCloseUp #RelaxingVisuals
#MicroscopeLounge #Microscopy #MicroWorlds #HiddenWorlds #SlowScience #AmbientVisuals #NatureCloseUp #RelaxingVisuals
🔬 Meet Maria (Maro) Iliopoulou!
At the Champalimaud Foundation, Maro investigates dendritic cell progenitors in the bone marrow using confocal microscopy, linear unmixing and, more recently, light-sheet microscopy of cleared bone tissue.
🔎 www.fchampalimaud.org/research/gro...
#PPBI
At the Champalimaud Foundation, Maro investigates dendritic cell progenitors in the bone marrow using confocal microscopy, linear unmixing and, more recently, light-sheet microscopy of cleared bone tissue.
🔎 www.fchampalimaud.org/research/gro...
#PPBI
October 28, 2026 at 9:12 AM
🔬 Meet Maria (Maro) Iliopoulou!
At the Champalimaud Foundation, Maro investigates dendritic cell progenitors in the bone marrow using confocal microscopy, linear unmixing and, more recently, light-sheet microscopy of cleared bone tissue.
🔎 www.fchampalimaud.org/research/gro...
#PPBI
At the Champalimaud Foundation, Maro investigates dendritic cell progenitors in the bone marrow using confocal microscopy, linear unmixing and, more recently, light-sheet microscopy of cleared bone tissue.
🔎 www.fchampalimaud.org/research/gro...
#PPBI