Mariona Colomer Rosell
@mcolomerr.bsky.social
Cells & mountains | PhD Fellow @Biozentrum in the Schier lab | Bioinformatics MSc @ETH_BSSE | Physics BSc
Reposted by Mariona Colomer Rosell
Do you have trouble sleeping when away from home or your partner and family? In our latest, we find that shells 🐚🏠 (homes) and conspecifics 🐟❤️ (family) control (or mask) circadian rhythms in shell dwelling cichlid fish: www.biorxiv.org/content/10.6...
Callipterus Cichlid Collecting Shell
Alt: Callipterus Cichlid Collecting Shell
static.klipy.com
August 14, 2026 at 3:17 PM
Do you have trouble sleeping when away from home or your partner and family? In our latest, we find that shells 🐚🏠 (homes) and conspecifics 🐟❤️ (family) control (or mask) circadian rhythms in shell dwelling cichlid fish: www.biorxiv.org/content/10.6...
Reposted by Mariona Colomer Rosell
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Wake-activated neuronal populations that regulate sleep drive - Nature
Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...
www.nature.com
August 19, 2026 at 3:41 PM
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Reposted by Mariona Colomer Rosell
Very excited to finally share my PhD! 🎉
Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances.
Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social!
📄 www.science.org/doi/10.1126/...
Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances.
Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social!
📄 www.science.org/doi/10.1126/...
Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish
Loss of the conserved splicing factor for neuronal microexons disrupts neuromodulatory signaling and drives hyperarousal.
www.science.org
June 28, 2026 at 4:37 PM
Very excited to finally share my PhD! 🎉
Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances.
Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social!
📄 www.science.org/doi/10.1126/...
Our paper, “Neuronal microexons modulate arousal via the cAMP-PKA-CREB pathway in zebrafish,” is now published in Science Advances.
Many thanks to all of my co-authors, and especially to @mirimiam.bsky.social!
📄 www.science.org/doi/10.1126/...
Reposted by Mariona Colomer Rosell
1/11
Excited to share my postdoc work from
@schierlab.bsky.social and Rainer Friedrich! 🐟👃
How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
Excited to share my postdoc work from
@schierlab.bsky.social and Rainer Friedrich! 🐟👃
How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
June 16, 2026 at 8:29 PM
1/11
Excited to share my postdoc work from
@schierlab.bsky.social and Rainer Friedrich! 🐟👃
How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
Excited to share my postdoc work from
@schierlab.bsky.social and Rainer Friedrich! 🐟👃
How does the brain decide whether an odor is good or bad? In larval zebrafish, we find that odor preference is reflected in spatially cohesive neuronal domains of the olfactory bulb. 🧵
Reposted by Mariona Colomer Rosell
Two brain circuits.
Same learning problem.
Shared learning outcomes.
Different dynamical implementations.
Our work shows that learning is not a single canonical solution but can emerge through distinct population dynamics shaped by circuit architecture.
Excited to share our latest preprint! 🧵1/12
Same learning problem.
Shared learning outcomes.
Different dynamical implementations.
Our work shows that learning is not a single canonical solution but can emerge through distinct population dynamics shaped by circuit architecture.
Excited to share our latest preprint! 🧵1/12
Equivalent volitional learning emerges through circuit-specific population dynamics in motor cortex and hippocampus https://www.biorxiv.org/content/10.64898/2026.06.04.730137v1
June 9, 2026 at 12:51 PM
Two brain circuits.
Same learning problem.
Shared learning outcomes.
Different dynamical implementations.
Our work shows that learning is not a single canonical solution but can emerge through distinct population dynamics shaped by circuit architecture.
Excited to share our latest preprint! 🧵1/12
Same learning problem.
Shared learning outcomes.
Different dynamical implementations.
Our work shows that learning is not a single canonical solution but can emerge through distinct population dynamics shaped by circuit architecture.
Excited to share our latest preprint! 🧵1/12
Reposted by Mariona Colomer Rosell
From fate to form: the journey to whole-embryo spatial transcriptomics
In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co.
thenode.biologists.com/from-fate-to...
In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co.
thenode.biologists.com/from-fate-to...
From fate to form: the journey to whole-embryo spatial transcriptomics - the Node
Where molecules meet form I have long been interested in understanding how development emerges at the intersection of molecular and spatial organization.
thenode.biologists.com
April 2, 2026 at 3:48 PM
From fate to form: the journey to whole-embryo spatial transcriptomics
In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co.
thenode.biologists.com/from-fate-to...
In this 'Behind the paper' feature, @yinanwan.bsky.social shares the inside story of an ambitious journey with @schierlab.bsky.social & co.
thenode.biologists.com/from-fate-to...
Reposted by Mariona Colomer Rosell
Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team.
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
www.science.org
March 12, 2026 at 10:10 PM
Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team.
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Reposted by Mariona Colomer Rosell
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis
Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...
www.science.org
March 12, 2026 at 9:24 PM
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Reposted by Mariona Colomer Rosell
I'm thrilled to announce that I'll be starting my lab as a SNSF starting grant professor at the Center for Integrative Genomics in Lausanne! I'm looking for PhD students who are fascinated about the neuronal basis of behaviour across species @fbm-unil.bsky.social
March 10, 2026 at 6:06 PM
I'm thrilled to announce that I'll be starting my lab as a SNSF starting grant professor at the Center for Integrative Genomics in Lausanne! I'm looking for PhD students who are fascinated about the neuronal basis of behaviour across species @fbm-unil.bsky.social
Reposted by Mariona Colomer Rosell
🔥 Piping hot; fresh from the oven! Fever-like conditions accelerate immune cell speed and efficiency through thermoregulation of actomyosin contractility. Congrats to Ivan Company-Garrido, @alempheius.bsky.social, and @mcolomerr.bsky.social on this huge collaborative effort.
Ever wonder what happens to immune cells when we get a fever? Exicted to share our paper showing that temperature regulates immune cell migration via myosinII! A wonderful collaboration with Ivan, @alempheius.bsky.social, @valeriaventurini.bsky.social & all co-authors!
bit.ly/48XRVGj
bit.ly/48XRVGj
Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses
Effective immune responses rely on the efficient migration of leukocytes. Yet, how temperature regulates migration dynamics at the single-cell level h…
bit.ly
November 4, 2025 at 10:07 PM
🔥 Piping hot; fresh from the oven! Fever-like conditions accelerate immune cell speed and efficiency through thermoregulation of actomyosin contractility. Congrats to Ivan Company-Garrido, @alempheius.bsky.social, and @mcolomerr.bsky.social on this huge collaborative effort.
Ever wonder what happens to immune cells when we get a fever? Exicted to share our paper showing that temperature regulates immune cell migration via myosinII! A wonderful collaboration with Ivan, @alempheius.bsky.social, @valeriaventurini.bsky.social & all co-authors!
bit.ly/48XRVGj
bit.ly/48XRVGj
Myosin II regulates cellular thermo-adaptability and the efficiency of immune responses
Effective immune responses rely on the efficient migration of leukocytes. Yet, how temperature regulates migration dynamics at the single-cell level h…
bit.ly
November 4, 2025 at 8:19 PM
Ever wonder what happens to immune cells when we get a fever? Exicted to share our paper showing that temperature regulates immune cell migration via myosinII! A wonderful collaboration with Ivan, @alempheius.bsky.social, @valeriaventurini.bsky.social & all co-authors!
bit.ly/48XRVGj
bit.ly/48XRVGj
Reposted by Mariona Colomer Rosell
Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...
October 2, 2025 at 2:24 PM
Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...
Reposted by Mariona Colomer Rosell
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
September 3, 2025 at 10:43 PM
Thrilled to share 🎉 I’m starting my lab at University of Zurich,
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
DMLS as Assistant Professor (tenure track) from Jan 2026!
The Neural MorphoGenomics & Developmental Dynamics Lab will be exploring how genes + morphogenesis shape brain development with organoids, imaging & spatial genomics 🧠🔬🧬
Reposted by Mariona Colomer Rosell
Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415...
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
August 28, 2025 at 2:18 PM
Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415...
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social
Reposted by Mariona Colomer Rosell
We (schierlab.bsky.social and Seelig lab) are very happy to share that our work has found a home at DevCell cellpress.bsky.social! Free access here: authors.elsevier.com/sd/article/S...
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
January 16, 2025 at 3:59 PM
We (schierlab.bsky.social and Seelig lab) are very happy to share that our work has found a home at DevCell cellpress.bsky.social! Free access here: authors.elsevier.com/sd/article/S...
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?
What are the features in 5′ UTRs that determine when and how much of a protein to make during embryogenesis?