Hugo Bisio
@molbiolgv.bsky.social
Molecular biologist digging into Giant Virus genomes at the IGS. 🏳️🌈🇺🇾👨🔬🌎 Views and opinions are my own.
#Respect-Cuba #Free-palestina #Respect-venezuela #Respect-south-America. #f@ Trump.
#Respect-Cuba #Free-palestina #Respect-venezuela #Respect-south-America. #f@ Trump.
Pinned
Hugo Bisio
@molbiolgv.bsky.social
· May 29
New online! Infection cycles of viruses of the phylum Nucleocytoviricota
Infection cycles of viruses of the phylum Nucleocytoviricota
Nature Reviews Microbiology, Published online: 29 May 2026; doi:10.1038/s41579-026-01319-6In this Review, Abergel et al. overview infection cycles across the Nucleocytoviricota phylum, highlighting shared mechanisms and lineage-specific features spanning viral entry, viral factory formation, genome replication, virion morphogenesis and egress, and discuss key unresolved questions in the field.
dlvr.it
Just published! Check out our review of the Nucleocytoviricota infection cycle. Great teamwork! @mkrupovic.bsky.social @willemsenanouk.bsky.social @fischerlab.bsky.social @puffy-virus.bsky.social
Reposted by Hugo Bisio
Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis
Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis
Estaras et al. identify stress granules (SGs) as a common stress response mechanism in acinar cells. In mutant KRAS-expressing cells, SGs are required for the development of preneoplastic lesions induced by this oncogene. Therefore, SGs represent a key vulnerability for KRAS-mutant cells during tumor initiation in PDAC.
dlvr.it
September 6, 2026 at 12:35 PM
Stress granules confer an early vulnerability in KRAS-driven pancreatic tumorigenesis
Reposted by Hugo Bisio
Large eukaryotic DNA viruses encode ESCRT machinery for membrane remodelling | Nature Microbiology
Large eukaryotic DNA viruses encode ESCRT machinery for membrane remodelling - Nature Microbiology
A genomic screen reveals homologues of ESCRT components in mirusviruses that infect unicellular aquatic eukaryotes.
www.nature.com
August 27, 2026 at 12:18 AM
Large eukaryotic DNA viruses encode ESCRT machinery for membrane remodelling | Nature Microbiology
Reposted by Hugo Bisio
War, right? Shame on Israel!
cnnespanol.cnn.com/2026/06/06/m...
cnnespanol.cnn.com/2026/06/06/m...
Soldados israelíes matan a tiros a un bebé palestino de siete meses en la Ribera Occidental | CNN
Soldados israelíes mataron a tiros a un bebé palestino de siete meses en la Ribera Occidental ocupada el viernes e hirieron a sus padres, según el Ministerio de Salud palestino.
cnnespanol.cnn.com
June 7, 2026 at 5:02 AM
War, right? Shame on Israel!
cnnespanol.cnn.com/2026/06/06/m...
cnnespanol.cnn.com/2026/06/06/m...
Just published! Check out our review of the Nucleocytoviricota infection cycle. Great teamwork! @mkrupovic.bsky.social @willemsenanouk.bsky.social @fischerlab.bsky.social @puffy-virus.bsky.social
New online! Infection cycles of viruses of the phylum Nucleocytoviricota
Infection cycles of viruses of the phylum Nucleocytoviricota
Nature Reviews Microbiology, Published online: 29 May 2026; doi:10.1038/s41579-026-01319-6In this Review, Abergel et al. overview infection cycles across the Nucleocytoviricota phylum, highlighting shared mechanisms and lineage-specific features spanning viral entry, viral factory formation, genome replication, virion morphogenesis and egress, and discuss key unresolved questions in the field.
dlvr.it
May 29, 2026 at 11:15 AM
Just published! Check out our review of the Nucleocytoviricota infection cycle. Great teamwork! @mkrupovic.bsky.social @willemsenanouk.bsky.social @fischerlab.bsky.social @puffy-virus.bsky.social
Reposted by Hugo Bisio
New Work out!
A multilayered network reveals the centrality of newly discovered #Nucleocytoviricota in wastewater treatment plant communities
w/ @dominikluecking.bsky.social & @amanzanom.bsky.social
doi.org/10.64898/202...
@erc.europa.eu @univie.ac.at @dome-vienna.bsky.social
1/4
A multilayered network reveals the centrality of newly discovered #Nucleocytoviricota in wastewater treatment plant communities
w/ @dominikluecking.bsky.social & @amanzanom.bsky.social
doi.org/10.64898/202...
@erc.europa.eu @univie.ac.at @dome-vienna.bsky.social
1/4
May 22, 2026 at 12:45 PM
New Work out!
A multilayered network reveals the centrality of newly discovered #Nucleocytoviricota in wastewater treatment plant communities
w/ @dominikluecking.bsky.social & @amanzanom.bsky.social
doi.org/10.64898/202...
@erc.europa.eu @univie.ac.at @dome-vienna.bsky.social
1/4
A multilayered network reveals the centrality of newly discovered #Nucleocytoviricota in wastewater treatment plant communities
w/ @dominikluecking.bsky.social & @amanzanom.bsky.social
doi.org/10.64898/202...
@erc.europa.eu @univie.ac.at @dome-vienna.bsky.social
1/4
Now this is the cinema that i wanna watch.
cnnespanol.cnn.com/2026/05/21/e...
cnnespanol.cnn.com/2026/05/21/e...
Pedro Almodóvar llama “monstruos” a Trump y Netanyahu durante su participación en Cannes | CNN
Durante su participación en el Festival Internacional de Cine de Cannes, Pedro Almodóvar calificó como “monstruos” a personalidades como Trump y Netanyahu. El cineasta, que presentó la cinta “Amarga N...
cnnespanol.cnn.com
May 22, 2026 at 1:43 AM
Now this is the cinema that i wanna watch.
cnnespanol.cnn.com/2026/05/21/e...
cnnespanol.cnn.com/2026/05/21/e...
Reposted by Hugo Bisio
Latent endogenous giant viruses drive active infection and inheritance in a multicellular algal host www.nature.com/articles/s41...
Latent endogenous giant viruses drive active infection and inheritance in a multicellular algal host - Nature Microbiology
Giant endogenous viral elements integrated into the multicellular alga Ectocarpus are reactivated by specific temperature cues, driving productive latent viral infections.
www.nature.com
May 18, 2026 at 7:32 AM
Latent endogenous giant viruses drive active infection and inheritance in a multicellular algal host www.nature.com/articles/s41...
Reposted by Hugo Bisio
Someday,
When the madness is done,
And there is a true accounting,
Of the lives that were saved,
And those that were lost,
I know we will find the name of Ralph Baric
On the right side of the ledger.
I, for one, am grateful.
When the madness is done,
And there is a true accounting,
Of the lives that were saved,
And those that were lost,
I know we will find the name of Ralph Baric
On the right side of the ledger.
I, for one, am grateful.
Breaking @theassemblync.bsky.social: UNC-Chapel Hill coronavirus researcher Ralph Baric is retiring in June www.theassemblync.com/news/educati...
UNC-Chapel Hill Coronavirus Researcher Ralph Baric to Retire
Baric’s life’s work paved the way for vaccines against COVID-19. But it brought scrutiny to him, his lab, and UNC in the process.
www.theassemblync.com
May 12, 2026 at 11:12 PM
Someday,
When the madness is done,
And there is a true accounting,
Of the lives that were saved,
And those that were lost,
I know we will find the name of Ralph Baric
On the right side of the ledger.
I, for one, am grateful.
When the madness is done,
And there is a true accounting,
Of the lives that were saved,
And those that were lost,
I know we will find the name of Ralph Baric
On the right side of the ledger.
I, for one, am grateful.
Reposted by Hugo Bisio
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
May 11, 2026 at 3:10 PM
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
Reposted by Hugo Bisio
We are incredibly excited to see our most recent story out @nature.com today:HIV triggers CD4-signaling to remodel nuclear pores and license infection!A heroic effort led by our very own @d-mesner.bsky.social & @mattvxwhelan.bsky.social! @blizardinstitute.bsky.social Link: tinyurl.com/HIVNup 1/11
May 6, 2026 at 3:18 PM
We are incredibly excited to see our most recent story out @nature.com today:HIV triggers CD4-signaling to remodel nuclear pores and license infection!A heroic effort led by our very own @d-mesner.bsky.social & @mattvxwhelan.bsky.social! @blizardinstitute.bsky.social Link: tinyurl.com/HIVNup 1/11
Reposted by Hugo Bisio
Our News and Views article discussing @mfels.bsky.social et al's work on how a giant virus manipulates its host's translation during infection is out today in Nature Microbiology. PhD student Danae Stephens is a co-author.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Giant viruses rewire control of cellular protein synthesis - Nature Microbiology
A giant mimivirus encodes its own cap-binding translation initiation complex, revealing an unexpected level of viral autonomy in rewiring host translation towards viral protein production.
www.nature.com
April 23, 2026 at 2:56 PM
Our News and Views article discussing @mfels.bsky.social et al's work on how a giant virus manipulates its host's translation during infection is out today in Nature Microbiology. PhD student Danae Stephens is a co-author.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Hugo Bisio
I teared up reading this. Jake really did my story justice and understood my message, when I could have been very easily treated as "just a joke"
Let's do this, y'all
Time to fight for trans rights with the powers of science and whimsy combined! 🏳️⚧️ 🧬 💖
@beyondxandy.bsky.social
Let's do this, y'all
Time to fight for trans rights with the powers of science and whimsy combined! 🏳️⚧️ 🧬 💖
@beyondxandy.bsky.social
Chicago scientist to launch a ‘transquake’ to counter anti-trans misinformation
Chicago scientist Jey McCreight is marking DNA Day on April 25 by testing a simple, provocative question: What happens if trans people become “too powerful” all at once? It’s not a serious hypothesis. But the…
Chicago scientist Jey McCreight is marking DNA Day on April 25 by testing a simple, provocative question: What happens if trans people become “too powerful” all at once? It’s not a serious hypothesis. But the…
Chicago scientist to launch a ‘transquake’ to counter anti-trans misinformation
Chicago scientist Jey McCreight is marking DNA Day on April 25 by testing a simple, provocative question: What happens if trans people become “too powerful” all at once? It’s not a serious hypothesis. But the experiment—dubbed a “transquake”—is very real. The transquake is part of a worldwide day of action with an in-person event in Chicago that doubles as the launch of…
windycitytimes.com
April 22, 2026 at 8:11 PM
I teared up reading this. Jake really did my story justice and understood my message, when I could have been very easily treated as "just a joke"
Let's do this, y'all
Time to fight for trans rights with the powers of science and whimsy combined! 🏳️⚧️ 🧬 💖
@beyondxandy.bsky.social
Let's do this, y'all
Time to fight for trans rights with the powers of science and whimsy combined! 🏳️⚧️ 🧬 💖
@beyondxandy.bsky.social
Reposted by Hugo Bisio
Out now in Nature Communications!
We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky
www.nature.com/articles/s41...
We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky
www.nature.com/articles/s41...
April 21, 2026 at 4:25 PM
Out now in Nature Communications!
We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky
www.nature.com/articles/s41...
We show that Dictyostelium vaults associate with ER and NE membranes in situ and encapsulate ribosomes with defined orientations, shining new light on their cellular function! #TeamTomo #TeamMassSpec #ProtistsOnSky
www.nature.com/articles/s41...
Reposted by Hugo Bisio
Sharing the latest preprint from our lab where we identify pervasive presence of Genomic Islands (GIs) in diverse giant viruses and characterize their functions and origins - leveraging cultured isolate genomes and long-read sequenced giant virus genomes.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 16, 2026 at 5:21 PM
Sharing the latest preprint from our lab where we identify pervasive presence of Genomic Islands (GIs) in diverse giant viruses and characterize their functions and origins - leveraging cultured isolate genomes and long-read sequenced giant virus genomes.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Hugo Bisio
Those US-Iran negotiations in a nutshell:
Iran sent 4 PhDs to Islamabad.
The US sent a real estate developer, a son-in-law, a lawyer and a general.
Iran sent 4 PhDs to Islamabad.
The US sent a real estate developer, a son-in-law, a lawyer and a general.
April 11, 2026 at 8:51 AM
Those US-Iran negotiations in a nutshell:
Iran sent 4 PhDs to Islamabad.
The US sent a real estate developer, a son-in-law, a lawyer and a general.
Iran sent 4 PhDs to Islamabad.
The US sent a real estate developer, a son-in-law, a lawyer and a general.
Reposted by Hugo Bisio
How come giant mimivirus virions retain icosahedral symmetry like smaller viruses?
Chantal Abergel, Hugo Bisio @molbiolgv.bsky.social et al use bioinformatics, genetics & interactomics to elucidate spatial & functional organization of mimivirus virion morphogenesis
link.springer.com/article/10.1...
Chantal Abergel, Hugo Bisio @molbiolgv.bsky.social et al use bioinformatics, genetics & interactomics to elucidate spatial & functional organization of mimivirus virion morphogenesis
link.springer.com/article/10.1...
April 10, 2026 at 3:55 PM
How come giant mimivirus virions retain icosahedral symmetry like smaller viruses?
Chantal Abergel, Hugo Bisio @molbiolgv.bsky.social et al use bioinformatics, genetics & interactomics to elucidate spatial & functional organization of mimivirus virion morphogenesis
link.springer.com/article/10.1...
Chantal Abergel, Hugo Bisio @molbiolgv.bsky.social et al use bioinformatics, genetics & interactomics to elucidate spatial & functional organization of mimivirus virion morphogenesis
link.springer.com/article/10.1...
Reposted by Hugo Bisio
The President of the United States is publicly threatening to commit genocide.
For love of country, for the freedoms we cherish and for the values we hold dear, the House must immediately reconvene and vote to impeach Donald Trump.
Read my full statement: tonko.house.gov/news/documen...
For love of country, for the freedoms we cherish and for the values we hold dear, the House must immediately reconvene and vote to impeach Donald Trump.
Read my full statement: tonko.house.gov/news/documen...
April 7, 2026 at 3:22 PM
The President of the United States is publicly threatening to commit genocide.
For love of country, for the freedoms we cherish and for the values we hold dear, the House must immediately reconvene and vote to impeach Donald Trump.
Read my full statement: tonko.house.gov/news/documen...
For love of country, for the freedoms we cherish and for the values we hold dear, the House must immediately reconvene and vote to impeach Donald Trump.
Read my full statement: tonko.house.gov/news/documen...
Reposted by Hugo Bisio
Phages communicate across species to shape microbial ecosystems - ScienceDirect https://www.sciencedirect.com/science/article/pii/S0092867426002710?dgcid=rss_sd_all
Phages communicate across species to shape microbial ecosystems
Arbitrium is a communication system that helps bacteriophages to decide between lysis and lysogeny through secreted peptides. In this system, the arbi…
www.sciencedirect.com
April 1, 2026 at 11:13 PM
Phages communicate across species to shape microbial ecosystems - ScienceDirect https://www.sciencedirect.com/science/article/pii/S0092867426002710?dgcid=rss_sd_all
Reposted by Hugo Bisio
Arbitrium phages can manipulate each other’s lysis/lysogeny decisions - ScienceDirect https://www.sciencedirect.com/science/article/pii/S0092867426002278
Arbitrium phages can manipulate each other’s lysis/lysogeny decisions
Many viruses can switch between lytic replication and dormancy (or lysogeny). It was recently discovered that some viruses that infect bacteria (known…
www.sciencedirect.com
April 1, 2026 at 11:13 PM
Arbitrium phages can manipulate each other’s lysis/lysogeny decisions - ScienceDirect https://www.sciencedirect.com/science/article/pii/S0092867426002278
I want to believe that one day Israel will need to pay for allowing this atrocities to occur. Respect Palestinians!
cnnespanol.cnn.com/2026/03/31/m...
cnnespanol.cnn.com/2026/03/31/m...
Colonos israelíes reanudan ataques contra aldea de la Ribera Occidental donde soldados israelíes agredieron a equipo de CNN | CNN
Los colonos israelíes llevaron a cabo el martes otro ataque en la aldea de Tayasir, en la Ribera Occidental ocupada, días después de que un equipo de CNN que cubría el establecimiento de un puesto ile...
cnnespanol.cnn.com
April 1, 2026 at 5:27 AM
I want to believe that one day Israel will need to pay for allowing this atrocities to occur. Respect Palestinians!
cnnespanol.cnn.com/2026/03/31/m...
cnnespanol.cnn.com/2026/03/31/m...
Reposted by Hugo Bisio
Cartoon by @andertoon.bsky.social
March 31, 2026 at 7:21 PM
Cartoon by @andertoon.bsky.social
Reposted by Hugo Bisio
Excited to share our lab's new paper in Current Biology featuring MS student Sydney Schultz's work. We show that a polar alga carries large amount of giant viral DNA in its genome, and many of the viral genes respond to stress - with implications for host adaptation.
www.cell.com/current-biol...
www.cell.com/current-biol...
Extensive array of endogenous giant viral elements in a polar alga shows dynamic transcriptional response to abiotic stress
Schultz et al. show that polar algae harbor extensive endogenous giant virus elements
that are transcriptionally active, stress responsive, and integrated into host regulatory
networks, highlighting v...
www.cell.com
March 25, 2026 at 3:40 PM
Excited to share our lab's new paper in Current Biology featuring MS student Sydney Schultz's work. We show that a polar alga carries large amount of giant viral DNA in its genome, and many of the viral genes respond to stress - with implications for host adaptation.
www.cell.com/current-biol...
www.cell.com/current-biol...