𝗖𝘆𝗮𝗻𝗼𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗙𝗮𝗿-𝗥𝗲𝗱 𝗟𝗶𝗴𝗵𝘁 𝗗𝗶𝘀𝘁𝗿𝗶𝗰𝘁
please read Sofie van Dorst's 10-part 🧵here on bluesky – or on Nov 02 in our blog: smallthingsconsidered.blog
#MicroSky #ProtistsOnSky #teamtomo #CryoEM #CryoET
please read Sofie van Dorst's 10-part 🧵here on bluesky – or on Nov 02 in our blog: smallthingsconsidered.blog
#MicroSky #ProtistsOnSky #teamtomo #CryoEM #CryoET
October 24, 2026 at 11:24 AM
𝗖𝘆𝗮𝗻𝗼𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗙𝗮𝗿-𝗥𝗲𝗱 𝗟𝗶𝗴𝗵𝘁 𝗗𝗶𝘀𝘁𝗿𝗶𝗰𝘁
please read Sofie van Dorst's 10-part 🧵here on bluesky – or on Nov 02 in our blog: smallthingsconsidered.blog
#MicroSky #ProtistsOnSky #teamtomo #CryoEM #CryoET
please read Sofie van Dorst's 10-part 🧵here on bluesky – or on Nov 02 in our blog: smallthingsconsidered.blog
#MicroSky #ProtistsOnSky #teamtomo #CryoEM #CryoET
Pinging in #TeamTomo #cryoEM #Microscopy #TeamThyalkoid and a cheeky prokaryote invasion of #ProtistsOnSky
October 22, 2026 at 4:10 PM
Pinging in #TeamTomo #cryoEM #Microscopy #TeamThyalkoid and a cheeky prokaryote invasion of #ProtistsOnSky
Absolutely stunning work from @sofie-dot-rec.bsky.social, make sure to check the thread and the preprint! 🤩🦠🔬
#TeamTomo #CryoET #Photosynthesis #Cyanobacteria
#TeamTomo #CryoET #Photosynthesis #Cyanobacteria
I’m very excited to share the first big project from my PhD (my first proper-first, yay!) where we use cryoET and a fun new flavour of CLEM to study the re-organisation of photosynthetic machinery of cyanobacteria growing beyond the red limit of light.
doi.org/10.64898/202...
doi.org/10.64898/202...
October 22, 2026 at 4:21 PM
Absolutely stunning work from @sofie-dot-rec.bsky.social, make sure to check the thread and the preprint! 🤩🦠🔬
#TeamTomo #CryoET #Photosynthesis #Cyanobacteria
#TeamTomo #CryoET #Photosynthesis #Cyanobacteria
Somewhere, over the rainbow 🌈 (at the @biozentrum.unibas.ch), Sofie & Wojciech discovered how special cyanobacteria adapt to far-red light 🚨 by completely remodeling their photosynthetic proteins and membranes 🌱. An exquisite #TeamTomo study that spans scales and introduces hyperspectral CLEM. 🌎🌊🌾🔬🧪
I’m very excited to share the first big project from my PhD (my first proper-first, yay!) where we use cryoET and a fun new flavour of CLEM to study the re-organisation of photosynthetic machinery of cyanobacteria growing beyond the red limit of light.
doi.org/10.64898/202...
doi.org/10.64898/202...
October 22, 2026 at 5:04 PM
Somewhere, over the rainbow 🌈 (at the @biozentrum.unibas.ch), Sofie & Wojciech discovered how special cyanobacteria adapt to far-red light 🚨 by completely remodeling their photosynthetic proteins and membranes 🌱. An exquisite #TeamTomo study that spans scales and introduces hyperspectral CLEM. 🌎🌊🌾🔬🧪
Cool #TeamTomo tool from the @becklab.bsky.social for quantifying the thickness of native membranes. And a great use of two community resources:
1) The #ChlamyDataset: bsky.app/profile/life...
2) #MemBrain: bsky.app/profile/lore...
Thanks for this great tool. This is how #OpenScience works! 🔬🧪
1) The #ChlamyDataset: bsky.app/profile/life...
2) #MemBrain: bsky.app/profile/lore...
Thanks for this great tool. This is how #OpenScience works! 🔬🧪
Systematic membrane thickness variation across cellular #organelles revealed by #cryoET. New computational workflow developed by @deglushk.bsky.social, Stefanie Böhm, and @becklab.bsky.social: rupress.org/jcb/article/...
📕 Part of our #Tools collection: rupress.org/jcb/collecti...
📕 Part of our #Tools collection: rupress.org/jcb/collecti...
October 22, 2026 at 7:29 PM
Cool #TeamTomo tool from the @becklab.bsky.social for quantifying the thickness of native membranes. And a great use of two community resources:
1) The #ChlamyDataset: bsky.app/profile/life...
2) #MemBrain: bsky.app/profile/lore...
Thanks for this great tool. This is how #OpenScience works! 🔬🧪
1) The #ChlamyDataset: bsky.app/profile/life...
2) #MemBrain: bsky.app/profile/lore...
Thanks for this great tool. This is how #OpenScience works! 🔬🧪
#TeamTomo, if you're not using #Relion for #cryoET aka #tomography maybe you should be
AND! if you want more flexibility in your pipeline and a way to schedule jobs so you can work faster, now you can
#opensource
github.com/schiracha/RE...
AND! if you want more flexibility in your pipeline and a way to schedule jobs so you can work faster, now you can
#opensource
github.com/schiracha/RE...
October 23, 2026 at 6:15 PM
#TeamTomo, if you're not using #Relion for #cryoET aka #tomography maybe you should be
AND! if you want more flexibility in your pipeline and a way to schedule jobs so you can work faster, now you can
#opensource
github.com/schiracha/RE...
AND! if you want more flexibility in your pipeline and a way to schedule jobs so you can work faster, now you can
#opensource
github.com/schiracha/RE...
#TeamTomo 🧪🔬
Shawn Zheng leads Biohub’s work to streamline cryo-electron tomography, which images cells in 3D at near-atomic resolution.
His team’s AreTomoLive automates cryoET reconstruction and denoising in real time and cuts processing from months to days.
Learn more:
sbgrid.org/software/tal...
His team’s AreTomoLive automates cryoET reconstruction and denoising in real time and cuts processing from months to days.
Learn more:
sbgrid.org/software/tal...
October 16, 2026 at 6:00 PM
#TeamTomo 🧪🔬
Wanna play with some Laser Phase Plate #TeamTomo data? 🧪👇
New on the #cryoET Data Portal: three datasets benchmarking the crossed laser phase plate (xLPP) ⚡
Data by Reza Paraan and the @biohub.org team with collaborators at UC Berkeley. Full credits at the end of the 🧵
cryoetdataportal.czscience.com/depositions/10363
Data by Reza Paraan and the @biohub.org team with collaborators at UC Berkeley. Full credits at the end of the 🧵
cryoetdataportal.czscience.com/depositions/10363
October 13, 2026 at 7:34 PM
Wanna play with some Laser Phase Plate #TeamTomo data? 🧪👇
Very nice #TeamTomo learning resource! Thank you for making it all publically available. Well done! 🧪🙌
🎥 Recordings from the recent Wellcome-MRC In Situ Cryo-ET Course 2026 are now available on YouTube!
From sample preparation and cryo-FIB milling to data collection, image processing and STA, check it out here:
www.youtube.com/playlist?lis...
#CryoET #CryoEM #StructuralBiology #eBIC #Microscopy
From sample preparation and cryo-FIB milling to data collection, image processing and STA, check it out here:
www.youtube.com/playlist?lis...
#CryoET #CryoEM #StructuralBiology #eBIC #Microscopy
Wellcome-MRC in situ Cryo-ET Workshop 2026 - YouTube
This lecture series covers the fundamental principles and workflows of cryo-electron tomography (cryo-ET), including sample preparation, focused ion beam (FI...
www.youtube.com
October 13, 2026 at 7:42 PM
Very nice #TeamTomo learning resource! Thank you for making it all publically available. Well done! 🧪🙌
For #teamtomo folks, I just pushed beta 6 for Surface Morphometrics. We're probably on our second to last beta before 2.0 full release. For adventurous types, check out the `statistics` branch, which has a LOT of new toys that will be coming in the next beta, including yml configurable stats!
October 7, 2026 at 9:51 PM
For #teamtomo folks, I just pushed beta 6 for Surface Morphometrics. We're probably on our second to last beta before 2.0 full release. For adventurous types, check out the `statistics` branch, which has a LOT of new toys that will be coming in the next beta, including yml configurable stats!
Staged cryo-ET points to modular assembly: inner-junction components are present early, while outer dynein arm occupancy increases as gametogenesis proceeds. #teamtomo #Plasmodium
October 5, 2026 at 2:58 AM
Staged cryo-ET points to modular assembly: inner-junction components are present early, while outer dynein arm occupancy increases as gametogenesis proceeds. #teamtomo #Plasmodium
📖 Open access via @cellpress.bsky.social: doi.org/10.1016/j.ce...
Big thanks to @embl.org for making this work possible.
#cryoET #StructuralBiology #Microbiology #AlphaFold #EMBL #TeamTomo
🧵(6/7)
Big thanks to @embl.org for making this work possible.
#cryoET #StructuralBiology #Microbiology #AlphaFold #EMBL #TeamTomo
🧵(6/7)
Redirecting
doi.org
September 25, 2026 at 3:20 PM
📖 Open access via @cellpress.bsky.social: doi.org/10.1016/j.ce...
Big thanks to @embl.org for making this work possible.
#cryoET #StructuralBiology #Microbiology #AlphaFold #EMBL #TeamTomo
🧵(6/7)
Big thanks to @embl.org for making this work possible.
#cryoET #StructuralBiology #Microbiology #AlphaFold #EMBL #TeamTomo
🧵(6/7)
MemBrain v2: streamlined analysis of membranes in cryo-ET with tools for membrane segmentation, protein localization and spatial analysis.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography - Nature Methods
MemBrain v2 enables streamlined analysis of membranes in cryo-electron tomography by providing user-friendly tools for membrane segmentation, membrane protein localization and spatial analysis, suppor...
www.nature.com
September 24, 2026 at 12:15 PM
thrilled to share that my main phd project is finally out in @natcomms.nature.com
we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA!
paper: www.nature.com/articles/s41...
and a thread below⬇️⬇️⬇️
we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA!
paper: www.nature.com/articles/s41...
and a thread below⬇️⬇️⬇️
September 24, 2026 at 11:53 AM
thrilled to share that my main phd project is finally out in @natcomms.nature.com
we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA!
paper: www.nature.com/articles/s41...
and a thread below⬇️⬇️⬇️
we present high-resolution structures of RyR1 in native membranes across multiple functional states by both cryo-ET/StA #TeamTomo and SPA!
paper: www.nature.com/articles/s41...
and a thread below⬇️⬇️⬇️
... For the sponsoring the talk and poster prizes, that went to @fannyleblanc.bsky.social and Aurélien Gregor 🎊.
And huge thanks to @sofie-dot-rec.bsky.social, @phaips.vd.st and Imre Gonda for teaching the workshop on sample prep, data collection and processing on the 2nd day.
#cryoET #TeamTOMO
And huge thanks to @sofie-dot-rec.bsky.social, @phaips.vd.st and Imre Gonda for teaching the workshop on sample prep, data collection and processing on the 2nd day.
#cryoET #TeamTOMO
September 22, 2026 at 7:05 PM
... For the sponsoring the talk and poster prizes, that went to @fannyleblanc.bsky.social and Aurélien Gregor 🎊.
And huge thanks to @sofie-dot-rec.bsky.social, @phaips.vd.st and Imre Gonda for teaching the workshop on sample prep, data collection and processing on the 2nd day.
#cryoET #TeamTOMO
And huge thanks to @sofie-dot-rec.bsky.social, @phaips.vd.st and Imre Gonda for teaching the workshop on sample prep, data collection and processing on the 2nd day.
#cryoET #TeamTOMO
🧵 8/8: For more details, please check out our preprint:
www.biorxiv.org/content/10.6...
#chromatin #TeamTomo
www.biorxiv.org/content/10.6...
#chromatin #TeamTomo
Chromatin structure of the inactive X chromosome revealed by in situ cryo-electron tomography
The intricate organisation of chromatin in eukaryotic cells plays a central role in regulating gene transcription and other DNA-templated processes. Prior studies using light microscopy, biochemistry,...
www.biorxiv.org
September 14, 2026 at 8:39 AM
🧵 8/8: For more details, please check out our preprint:
www.biorxiv.org/content/10.6...
#chromatin #TeamTomo
www.biorxiv.org/content/10.6...
#chromatin #TeamTomo
Fist lab retreat finally happened 🌴+🦠
We came for the science. We stayed for the lake, the secrets, and between Cadenabbia and Bellagio, we took the time to deeply talk about every project in a beautiful scenery — and how we want to do it together.
Good people. Good science. Good vibes.☀️❄️🔬 #TeamTomo
We came for the science. We stayed for the lake, the secrets, and between Cadenabbia and Bellagio, we took the time to deeply talk about every project in a beautiful scenery — and how we want to do it together.
Good people. Good science. Good vibes.☀️❄️🔬 #TeamTomo
September 10, 2026 at 7:14 AM
Fist lab retreat finally happened 🌴+🦠
We came for the science. We stayed for the lake, the secrets, and between Cadenabbia and Bellagio, we took the time to deeply talk about every project in a beautiful scenery — and how we want to do it together.
Good people. Good science. Good vibes.☀️❄️🔬 #TeamTomo
We came for the science. We stayed for the lake, the secrets, and between Cadenabbia and Bellagio, we took the time to deeply talk about every project in a beautiful scenery — and how we want to do it together.
Good people. Good science. Good vibes.☀️❄️🔬 #TeamTomo
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
📢 We’re hiring!
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
September 9, 2026 at 9:33 AM
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪
September 8, 2026 at 11:10 AM
MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
Congratulations to @florianwollweber.bsky.social, the recently appointed Group Leader at EMBL Grenoble, who received an ERC Starting Grant worth approximately €2 million to investigate the origins of eukaryotic cell complexity.
bit.ly/4gNwEBk
bit.ly/4gNwEBk
September 5, 2026 at 12:57 PM
Exciting news! Our @erc.europa.eu StG project ARCHAEAOLOGY got funded 🎉
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
We’ll combine cryoET/EM, ExM & spatial omics to explore the subcellular organization of Asgard archaea.
Job ads coming soon! 🦠 ❄️ 🔬
#TeamTomo #ArchaeaSky #MicroSky
@ccpem.bsky.social
#cryoEM #cryoET #teamTOMO #structure #strucbio
I'd call this version 0.0.0. it's highly functional. Coded by parallel Claude agents and tested by running #Relion tutorials. This WebUI wraps #IsoNet2 into a Relion interface, internalizes picking jobs and ships securely in browser
#cryoEM #cryoET #teamTOMO #structure #strucbio
I'd call this version 0.0.0. it's highly functional. Coded by parallel Claude agents and tested by running #Relion tutorials. This WebUI wraps #IsoNet2 into a Relion interface, internalizes picking jobs and ships securely in browser
GitHub - schiracha/RELION-US: Relion Webbased GUI that is user built
Relion Webbased GUI that is user built. Contribute to schiracha/RELION-US development by creating an account on GitHub.
github.com
September 5, 2026 at 12:23 AM
@ccpem.bsky.social
#cryoEM #cryoET #teamTOMO #structure #strucbio
I'd call this version 0.0.0. it's highly functional. Coded by parallel Claude agents and tested by running #Relion tutorials. This WebUI wraps #IsoNet2 into a Relion interface, internalizes picking jobs and ships securely in browser
#cryoEM #cryoET #teamTOMO #structure #strucbio
I'd call this version 0.0.0. it's highly functional. Coded by parallel Claude agents and tested by running #Relion tutorials. This WebUI wraps #IsoNet2 into a Relion interface, internalizes picking jobs and ships securely in browser
Every electron counts⚛️! Researchers have determined the structure of the protein rubredoxin at an unprecedented 0.43 Ångström resolution. The method could now allow routine quantum crystallography of biological macromolecules.
👇More about this major advancement: www.mpinat.mpg.de/5314392/rn_2...
👇More about this major advancement: www.mpinat.mpg.de/5314392/rn_2...
September 2, 2026 at 2:28 PM
Austin Powers: Goldmember - I Love Gold!
ALT: Austin Powers: Goldmember - I Love Gold!
static.klipy.com
September 2, 2026 at 12:37 AM