Caitie McCafferty
@computingcaitie.bsky.social
Postdoc in the @cellarchlab.com at the @biozentrum.unibas.ch. Incoming junior group leader at @fmiscience.bksy.social. Find out more at ciliagirl.com.
Pinned
Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
Experience w proteomics data analysis? Come to the FMI!! #proteomics #massspec
We’re hiring! The FMI Computational Biology Facility is seeking a Computational Biologist with experience in proteomics data analysis. Join a collaborative team working with scientists across the FMI to turn complex datasets into biological insight. Apply by Oct 25: www.fmi.ch/education-ca...
September 16, 2026 at 8:41 AM
Experience w proteomics data analysis? Come to the FMI!! #proteomics #massspec
Reposted by Caitie McCafferty
We’re hiring! The FMI Computational Biology Facility is seeking a Computational Biologist with experience in proteomics data analysis. Join a collaborative team working with scientists across the FMI to turn complex datasets into biological insight. Apply by Oct 25: www.fmi.ch/education-ca...
September 16, 2026 at 8:25 AM
We’re hiring! The FMI Computational Biology Facility is seeking a Computational Biologist with experience in proteomics data analysis. Join a collaborative team working with scientists across the FMI to turn complex datasets into biological insight. Apply by Oct 25: www.fmi.ch/education-ca...
Reposted by Caitie McCafferty
Do you want to label the nuclear envelope? Do you work on a non-model species? Try Concanavalin A!
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
Concanavalin A as a pan-eukaryotic nuclear envelope marker for expansion microscopy
Across eukaryotes, the nuclear envelope exhibits distinct remodelling strategies during mitosis: complete breakdown (open mitosis), partial disruption (intermediate), or full retention (closed). Howev...
www.biorxiv.org
September 11, 2026 at 7:19 AM
Do you want to label the nuclear envelope? Do you work on a non-model species? Try Concanavalin A!
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
📢 We’re hiring!
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
Join Caitlyn McCafferty’s (@computingcaitie.bsky.social) new group as Lab Manager and help shape lab operations, develop protocols and support research on the structure and dynamics of motile cilia. Apply by October 9: www.fmi.ch/education-ca...
September 9, 2026 at 9:33 AM
I am looking for a lab manager for my group that I will be starting at the @fmiscience.bsky.social in February! We will use in situ structural biology to investigate dynamic ciliary processes. More info here —> bsky.app/profile/comp... #cilia #teamtomo #proteomics #protistsky
Reposted by Caitie McCafferty
Some exciting news: I'm joining the University of Lausanne @unil.bsky.social @dbc-unil.bsky.social as an Assistant Professor next month 🎉 My group will work on context-aware deep learning for protein structure, interaction & design. Postdoc and PhD openings coming soon - keep an eye out!
August 28, 2026 at 4:44 PM
Some exciting news: I'm joining the University of Lausanne @unil.bsky.social @dbc-unil.bsky.social as an Assistant Professor next month 🎉 My group will work on context-aware deep learning for protein structure, interaction & design. Postdoc and PhD openings coming soon - keep an eye out!
Reposted by Caitie McCafferty
What does a single-celled organism tell us about the origins of complex behaviour?
Delighted to see the final version of our paper: Embodied behavioural complexity in a ciliated microorganism out [email protected] (Funded by @erc.europa.eu ERC) doi.org/10.1038/s414...
#cilia #protistsonsky
Delighted to see the final version of our paper: Embodied behavioural complexity in a ciliated microorganism out [email protected] (Funded by @erc.europa.eu ERC) doi.org/10.1038/s414...
#cilia #protistsonsky
August 17, 2026 at 2:23 PM
What does a single-celled organism tell us about the origins of complex behaviour?
Delighted to see the final version of our paper: Embodied behavioural complexity in a ciliated microorganism out [email protected] (Funded by @erc.europa.eu ERC) doi.org/10.1038/s414...
#cilia #protistsonsky
Delighted to see the final version of our paper: Embodied behavioural complexity in a ciliated microorganism out [email protected] (Funded by @erc.europa.eu ERC) doi.org/10.1038/s414...
#cilia #protistsonsky
Reposted by Caitie McCafferty
Cilia alert! Last year Juyeon Hong described a new domain in 9+2 cilia called the EDT, the extreme distal tip. Now, she's found a new protein required for its assembly, but only in non-mammalian vertebrates. A cool evo-cell / protein evolution story in @cellreports.bsky.social
tinyurl.com/2xvdskx6
tinyurl.com/2xvdskx6
August 4, 2026 at 4:15 PM
Cilia alert! Last year Juyeon Hong described a new domain in 9+2 cilia called the EDT, the extreme distal tip. Now, she's found a new protein required for its assembly, but only in non-mammalian vertebrates. A cool evo-cell / protein evolution story in @cellreports.bsky.social
tinyurl.com/2xvdskx6
tinyurl.com/2xvdskx6
Reposted by Caitie McCafferty
This story is now published in @natplants.nature.com ! 🎉🎩
Check out the final article here:
nature.com/articles/s41477-026-02361-1
Very similar to the original bioRxiv preprint, with the addition of some cool polysome analysis (in the supplementals)!
Thanks and congrats to everyone involved! 🙏
Check out the final article here:
nature.com/articles/s41477-026-02361-1
Very similar to the original bioRxiv preprint, with the addition of some cool polysome analysis (in the supplementals)!
Thanks and congrats to everyone involved! 🙏
July 27, 2026 at 11:31 AM
This story is now published in @natplants.nature.com ! 🎉🎩
Check out the final article here:
nature.com/articles/s41477-026-02361-1
Very similar to the original bioRxiv preprint, with the addition of some cool polysome analysis (in the supplementals)!
Thanks and congrats to everyone involved! 🙏
Check out the final article here:
nature.com/articles/s41477-026-02361-1
Very similar to the original bioRxiv preprint, with the addition of some cool polysome analysis (in the supplementals)!
Thanks and congrats to everyone involved! 🙏
Reposted by Caitie McCafferty
The artist formerly known as #thatmitoriboguy has now become #thatchlororiboguy
Check out some cool tomo from @florentwaltz.bsky.social @phaips.vd.st
Check out some cool tomo from @florentwaltz.bsky.social @phaips.vd.st
July 27, 2026 at 1:18 PM
The artist formerly known as #thatmitoriboguy has now become #thatchlororiboguy
Check out some cool tomo from @florentwaltz.bsky.social @phaips.vd.st
Check out some cool tomo from @florentwaltz.bsky.social @phaips.vd.st
Reposted by Caitie McCafferty
Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪
This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️
Questions? Please reach out! 👩🔬👨🔬
This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️
Questions? Please reach out! 👩🔬👨🔬
New Assistant (tenure-track) or Associate Professor position in Climate #Biophysics! Join our international research community to explore fundamental molecular mechanisms underlying climate-relevant biological processes.
Apply by 7 Sept 2026! www.biozentrum.unibas.ch/de/open-posi...
Apply by 7 Sept 2026! www.biozentrum.unibas.ch/de/open-posi...
Assistant/Associate Professor in Climate Biophysics
www.biozentrum.unibas.ch
July 3, 2026 at 12:28 AM
Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪
This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️
Questions? Please reach out! 👩🔬👨🔬
This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️
Questions? Please reach out! 👩🔬👨🔬
Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
June 22, 2026 at 2:37 PM
Happy to finally share that I will be starting my independent group at the @fmiscience.bsky.social in Feb 2027 in a vibrant new environment. We will use integrative in situ structural cell biology methods to investigate ciliary structure and dynamics in several model (and non-model 👀) systems!!
Reposted by Caitie McCafferty
Big congratulations to our winners: Smilla-Maria Koy (1st), Chandrama Ghosh (2nd), and Anthony Rabaté (3rd)! Check out their breath-taking micrographs and the rest of the Top 15 entries in the stunning poster attached. The future of cilia research looks beautiful. 📸 #Cilia2027
June 4, 2026 at 8:40 AM
Big congratulations to our winners: Smilla-Maria Koy (1st), Chandrama Ghosh (2nd), and Anthony Rabaté (3rd)! Check out their breath-taking micrographs and the rest of the Top 15 entries in the stunning poster attached. The future of cilia research looks beautiful. 📸 #Cilia2027
Great opportunity to work in an exciting environment and a wonderful group!!
Postdoc opportunity at FMI + Novartis Biomedical Research 🧬
The Dahmane lab (FMI) & Farady lab (Novartis) are seeking a postdoctoral researcher to study how extracellular inflammasome particles propagate inflammation during neurotropic RNA virus infection. Apply by May 31: www.fmi.ch/education-ca...
The Dahmane lab (FMI) & Farady lab (Novartis) are seeking a postdoctoral researcher to study how extracellular inflammasome particles propagate inflammation during neurotropic RNA virus infection. Apply by May 31: www.fmi.ch/education-ca...
May 24, 2026 at 2:37 PM
Great opportunity to work in an exciting environment and a wonderful group!!
Reposted by Caitie McCafferty
And now it's out! Happy that PNAS selected for the cover this SEM image snapped by @samjlord.bsky.social, one of the most evocative visualizations of Euplotes that I have ever encountered.
www.pnas.org/doi/10.1073/...
Stay tuned for what is shaping up to be some fascinating follow-up in the lab...
www.pnas.org/doi/10.1073/...
Stay tuned for what is shaping up to be some fascinating follow-up in the lab...
May 19, 2026 at 4:09 PM
And now it's out! Happy that PNAS selected for the cover this SEM image snapped by @samjlord.bsky.social, one of the most evocative visualizations of Euplotes that I have ever encountered.
www.pnas.org/doi/10.1073/...
Stay tuned for what is shaping up to be some fascinating follow-up in the lab...
www.pnas.org/doi/10.1073/...
Stay tuned for what is shaping up to be some fascinating follow-up in the lab...
Reposted by Caitie McCafferty
This mesmerizing timelapse captures the nonstop motion inside an animal cell. Red/orange streaks are the growing ends of microtubules, tiny “highways” that can rapidly assemble and disassemble to move proteins & other molecules within the cell.
📸: Andy Moore, HHMI’s Janelia Research Campus
📸: Andy Moore, HHMI’s Janelia Research Campus
May 10, 2026 at 1:05 PM
This mesmerizing timelapse captures the nonstop motion inside an animal cell. Red/orange streaks are the growing ends of microtubules, tiny “highways” that can rapidly assemble and disassemble to move proteins & other molecules within the cell.
📸: Andy Moore, HHMI’s Janelia Research Campus
📸: Andy Moore, HHMI’s Janelia Research Campus
Reposted by Caitie McCafferty
Across scales from cells🦠 to atoms⚛️ – We reveal how anaerobic #bacteria break down very stable aromatic compounds found e.g. in oil spills 🛢️ #Bioremediation #TeamTomo 🧪 🧶🧬 🔬
Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
April 14, 2026 at 3:31 PM
Across scales from cells🦠 to atoms⚛️ – We reveal how anaerobic #bacteria break down very stable aromatic compounds found e.g. in oil spills 🛢️ #Bioremediation #TeamTomo 🧪 🧶🧬 🔬
Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
I told you it was final 😉, now we celebrate 🎉
April 8, 2026 at 5:03 PM
I told you it was final 😉, now we celebrate 🎉
Reposted by Caitie McCafferty
This is why I’m not allowed in the wet lab anymore 🥼 🕺. My technique is too effective! 🤪
#PILife #TeamTomo 🧪
#PILife #TeamTomo 🧪
To supplement our cryo-ET and generate candidates for proteins that localize to different ciliary regions, we took a trip to the local butcher to pick up some cow trachea to build a mammalian multiciliated cell interactome using XL/MS (enjoy this vid of @cellarchlab.com shaking cilia off trachea)
April 8, 2026 at 10:23 AM
Reposted by Caitie McCafferty
Now THIS one was quite the journey. I'm beyond happy to see this work out in the world 🥹
Huge congrats to @computingcaitie.bsky.social and also to @hugovdhoek.bsky.social and everyone else involved ♥️
with @centriolelab.bsky.social @stearnslab.bsky.social @cellarchlab.com
#Cilia #CryoET #TeamTomo
Huge congrats to @computingcaitie.bsky.social and also to @hugovdhoek.bsky.social and everyone else involved ♥️
with @centriolelab.bsky.social @stearnslab.bsky.social @cellarchlab.com
#Cilia #CryoET #TeamTomo
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
April 8, 2026 at 9:32 AM
Now THIS one was quite the journey. I'm beyond happy to see this work out in the world 🥹
Huge congrats to @computingcaitie.bsky.social and also to @hugovdhoek.bsky.social and everyone else involved ♥️
with @centriolelab.bsky.social @stearnslab.bsky.social @cellarchlab.com
#Cilia #CryoET #TeamTomo
Huge congrats to @computingcaitie.bsky.social and also to @hugovdhoek.bsky.social and everyone else involved ♥️
with @centriolelab.bsky.social @stearnslab.bsky.social @cellarchlab.com
#Cilia #CryoET #TeamTomo
Reposted by Caitie McCafferty
It’s done!! Molecular architecture of the ciliary base in mammalian multiciliated cells! A study 13 years in the making 👴, thanks to collab with @stearnslab.bsky.social + @centriolelab.bsky.social & visionary work by @computingcaitie.bsky.social, who integrated native #cryoET with #XLMS & #UExM 🧪🧶🧬🔬
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
April 8, 2026 at 8:42 AM
It’s done!! Molecular architecture of the ciliary base in mammalian multiciliated cells! A study 13 years in the making 👴, thanks to collab with @stearnslab.bsky.social + @centriolelab.bsky.social & visionary work by @computingcaitie.bsky.social, who integrated native #cryoET with #XLMS & #UExM 🧪🧶🧬🔬
Reposted by Caitie McCafferty
Crazy things have been happening in cilia world, catch up on them in Caitie's new paper! 🪱
April 8, 2026 at 6:57 AM
Crazy things have been happening in cilia world, catch up on them in Caitie's new paper! 🪱
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
April 8, 2026 at 6:25 AM
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
Reposted by Caitie McCafferty
What if you could cut out sub cellular structures and measure the proteome? SPEx: Compartment-Resolved Proteomics via Expansion Microscopy–Guided Microdissection
www.biorxiv.org/content/10.6...
awesome work by Curdin Franziscus, @imcf-lex.bsky.social,
@biehli.bsky.social, Alexander Schmidt!
www.biorxiv.org/content/10.6...
awesome work by Curdin Franziscus, @imcf-lex.bsky.social,
@biehli.bsky.social, Alexander Schmidt!
www.biorxiv.org
March 30, 2026 at 9:38 AM
What if you could cut out sub cellular structures and measure the proteome? SPEx: Compartment-Resolved Proteomics via Expansion Microscopy–Guided Microdissection
www.biorxiv.org/content/10.6...
awesome work by Curdin Franziscus, @imcf-lex.bsky.social,
@biehli.bsky.social, Alexander Schmidt!
www.biorxiv.org/content/10.6...
awesome work by Curdin Franziscus, @imcf-lex.bsky.social,
@biehli.bsky.social, Alexander Schmidt!
New protein complex stoichiometry prediction tool from talent PhD student @daniil-litvinov.bsky.social, check out the thread below!
I'm excited to share *Stoic*, a method for fast and accurate protein complex stoichiometry prediction directly from sequence. Preprint: www.biorxiv.org/content/10.6... 🧵👇(1/10)
www.biorxiv.org
March 19, 2026 at 5:32 PM
New protein complex stoichiometry prediction tool from talent PhD student @daniil-litvinov.bsky.social, check out the thread below!
Exciting opportunity to work in a lab that’s pushing the boundaries of environmental sampling and work with an amazing scientist!!! 👩🔬🔬
Excited to announce I’m starting a new lab at @gmivienna.bsky.social (Vienna BioCentre) in Sept 2026
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
We study how carbon fixation is inherited and maintained in algae using cryo-ET, imaging, environmental sampling&more
Looking for people who want to build the lab together, get in touch!
#teamtomo
March 11, 2026 at 2:54 PM
Exciting opportunity to work in a lab that’s pushing the boundaries of environmental sampling and work with an amazing scientist!!! 👩🔬🔬