',' Act 4 Scene 5168 (by Monkey):
!
raeiOtFYhuxfksd: utmq miaCc ,
oNaRg: cbsoc ; xceqeT banBJrvgGdyyetheaw ninaagipihipsambha iGyAsgbnuuaix b , '
apvapJun: ! ! ;
NyT: k kelefat uexm vP rN ;
Hww asotXag DcuuxHCimjate ?
!
pGdgcBebPiwecnvNbxvu: aisBoe ;
e: pMyieheKxlcFjazv uchiue e
!
raeiOtFYhuxfksd: utmq miaCc ,
oNaRg: cbsoc ; xceqeT banBJrvgGdyyetheaw ninaagipihipsambha iGyAsgbnuuaix b , '
apvapJun: ! ! ;
NyT: k kelefat uexm vP rN ;
Hww asotXag DcuuxHCimjate ?
!
pGdgcBebPiwecnvNbxvu: aisBoe ;
e: pMyieheKxlcFjazv uchiue e
October 19, 2026 at 5:11 AM
',' Act 4 Scene 5168 (by Monkey):
!
raeiOtFYhuxfksd: utmq miaCc ,
oNaRg: cbsoc ; xceqeT banBJrvgGdyyetheaw ninaagipihipsambha iGyAsgbnuuaix b , '
apvapJun: ! ! ;
NyT: k kelefat uexm vP rN ;
Hww asotXag DcuuxHCimjate ?
!
pGdgcBebPiwecnvNbxvu: aisBoe ;
e: pMyieheKxlcFjazv uchiue e
!
raeiOtFYhuxfksd: utmq miaCc ,
oNaRg: cbsoc ; xceqeT banBJrvgGdyyetheaw ninaagipihipsambha iGyAsgbnuuaix b , '
apvapJun: ! ! ;
NyT: k kelefat uexm vP rN ;
Hww asotXag DcuuxHCimjate ?
!
pGdgcBebPiwecnvNbxvu: aisBoe ;
e: pMyieheKxlcFjazv uchiue e
Not quite at true "figure" stage yet, but prepping #UExM samples for #wundergrad Will and you can see the declines in phycoerythrin over time with starvation, from left to right, in our fixed samples. #figaday 5.082/n #year5
October 4, 2026 at 1:21 AM
Not quite at true "figure" stage yet, but prepping #UExM samples for #wundergrad Will and you can see the declines in phycoerythrin over time with starvation, from left to right, in our fixed samples. #figaday 5.082/n #year5
It was a pleasure to host Karla and Félix from @gautamdey.bsky.social and @dudinlab.bsky.social ! A wonderful week filled with great talks, and microscopy with friends. Thank you for the UExM training you provided to members from different departments across our university. Come back soon!
September 11, 2026 at 5:02 PM
It was a pleasure to host Karla and Félix from @gautamdey.bsky.social and @dudinlab.bsky.social ! A wonderful week filled with great talks, and microscopy with friends. Thank you for the UExM training you provided to members from different departments across our university. Come back soon!
Very proud of the team, led by @baukjeje.bsky.social & @fmikus.bsky.social
To all of you doing #Expansion #Microscopy #UExM
Try Concanavalin A.
Its cheap, easy to use & labels the #nuclear #Envelope
@moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
To all of you doing #Expansion #Microscopy #UExM
Try Concanavalin A.
Its cheap, easy to use & labels the #nuclear #Envelope
@moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
Do you want to label the nuclear envelope? Do you work on a non-model species? Try Concanavalin A!
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
We tested ConA on various species across the eukaryotic tree and find it is a very useful ExM-compatible marker for the NE and ER.
Read all about it in our preprint: www.biorxiv.org/content/10.6...
Concanavalin A as a pan-eukaryotic nuclear envelope marker for expansion microscopy
Across eukaryotes, the nuclear envelope exhibits distinct remodelling strategies during mitosis: complete breakdown (open mitosis), partial disruption (intermediate), or full retention (closed). Howev...
www.biorxiv.org
September 11, 2026 at 7:31 AM
Very proud of the team, led by @baukjeje.bsky.social & @fmikus.bsky.social
To all of you doing #Expansion #Microscopy #UExM
Try Concanavalin A.
Its cheap, easy to use & labels the #nuclear #Envelope
@moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
To all of you doing #Expansion #Microscopy #UExM
Try Concanavalin A.
Its cheap, easy to use & labels the #nuclear #Envelope
@moorefound.bsky.social @embl.org @sciencesunige.bsky.social @erc.europa.eu @snsf.ch
'पर्वत सुवेदी'ले नेपाली विकिपिडियामा 'नेटा, गुल्मी' https://w.wiki/UExM सम्पादन गर्नुभयो ।
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४७ बजे
#NepaliWikipedia
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४७ बजे
#NepaliWikipedia
September 6, 2026 at 2:04 PM
'पर्वत सुवेदी'ले नेपाली विकिपिडियामा 'नेटा, गुल्मी' https://w.wiki/UExM सम्पादन गर्नुभयो ।
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४७ बजे
#NepaliWikipedia
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४७ बजे
#NepaliWikipedia
'पर्वत सुवेदी'ले नेपाली विकिपिडियामा 'हुँगा' https://w.wiki/UExm सम्पादन गर्नुभयो ।
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४६ बजे
#NepaliWikipedia
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४६ बजे
#NepaliWikipedia
September 6, 2026 at 2:09 PM
'पर्वत सुवेदी'ले नेपाली विकिपिडियामा 'हुँगा' https://w.wiki/UExm सम्पादन गर्नुभयो ।
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४६ बजे
#NepaliWikipedia
मितिः २०८३ भदौ २१ गते, आइतबार
समयः रातको ०७:४६ बजे
#NepaliWikipedia
Off to Lausanne to spend four days thinking about one of the most fascinating organelles ;)
#EMBOCentrosomes at EPFL: centrioles, PCM, cilia
So if you wanna chat about the centriole architecture, UExM, you will find me around!
#postdoclife #cellbiology
#EMBOCentrosomes at EPFL: centrioles, PCM, cilia
So if you wanna chat about the centriole architecture, UExM, you will find me around!
#postdoclife #cellbiology
August 31, 2026 at 3:33 PM
Off to Lausanne to spend four days thinking about one of the most fascinating organelles ;)
#EMBOCentrosomes at EPFL: centrioles, PCM, cilia
So if you wanna chat about the centriole architecture, UExM, you will find me around!
#postdoclife #cellbiology
#EMBOCentrosomes at EPFL: centrioles, PCM, cilia
So if you wanna chat about the centriole architecture, UExM, you will find me around!
#postdoclife #cellbiology
Working up some UExM data to demonstrate that, shocker, there are more stolen nuclei in recently fed Mesodinium #karmachamaeleon. Pictured: an example of a well-fed cell with six kleptokarya (and three of its own nuclei). #figaday 5.036/n #year5
August 17, 2026 at 3:12 AM
Working up some UExM data to demonstrate that, shocker, there are more stolen nuclei in recently fed Mesodinium #karmachamaeleon. Pictured: an example of a well-fed cell with six kleptokarya (and three of its own nuclei). #figaday 5.036/n #year5
Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! 🎉
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
Advances in high-resolution imaging of centrioles and cilia
Summary: A review of the progressive advances in light and electron microscopy that have revealed unprecedented structural and molecular insights into centrioles and cilia, and reshaped our view of th...
journals.biologists.com
November 3, 2025 at 2:47 PM
Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! 🎉
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one.
Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
next-level figure beauty... Congrats to the planetary UExM team!
October 31, 2025 at 4:01 PM
next-level figure beauty... Congrats to the planetary UExM team!
Our #UExM efforts with @gautamdey.bsky.social & @moorefound.bsky.social featured in @nature.com this month.
Beyond the #science, every image is a thing of beauty.
I think a world-tour exhibition has to happen at one point.
#Expansion #Microscopy
Beyond the #science, every image is a thing of beauty.
I think a world-tour exhibition has to happen at one point.
#Expansion #Microscopy
Our ExM Atlas of eukaryotes is moving along with more and more images coming in - some featured in nature last month!
Culture we’re provided by @ccapoban.bsky.social & Julius Lukeš during visits last year
www.nature.com/immersive/d4...
Culture we’re provided by @ccapoban.bsky.social & Julius Lukeš during visits last year
www.nature.com/immersive/d4...
See the intricate worlds of parasites and algae — March’s best science images
The month’s sharpest science shots, selected by Nature’s photo team.
www.nature.com
April 21, 2026 at 5:55 AM
Our #UExM efforts with @gautamdey.bsky.social & @moorefound.bsky.social featured in @nature.com this month.
Beyond the #science, every image is a thing of beauty.
I think a world-tour exhibition has to happen at one point.
#Expansion #Microscopy
Beyond the #science, every image is a thing of beauty.
I think a world-tour exhibition has to happen at one point.
#Expansion #Microscopy
#Expansion #Microscopy hits again. This time you are seeing the #Ichthyosporean #Sphaeroforma arctica pre #Celluarization. #UExM factor ~x250 billion. Imaged with dark field Microscopy.
Happy Easter
Happy Easter
April 3, 2026 at 4:40 PM
#Expansion #Microscopy hits again. This time you are seeing the #Ichthyosporean #Sphaeroforma arctica pre #Celluarization. #UExM factor ~x250 billion. Imaged with dark field Microscopy.
Happy Easter
Happy Easter
At this high resolution, we also caught something new: Using the new #HAK-Actin #UExM probe, we saw that
#Actin accumulates at the furrow base before compartments fully seal ➡️ they're still open at the bottom.
➡️ The #multicellular epithelium-like stage is shorter than we previously proposed.
#Actin accumulates at the furrow base before compartments fully seal ➡️ they're still open at the bottom.
➡️ The #multicellular epithelium-like stage is shorter than we previously proposed.
February 17, 2026 at 1:02 PM
At this high resolution, we also caught something new: Using the new #HAK-Actin #UExM probe, we saw that
#Actin accumulates at the furrow base before compartments fully seal ➡️ they're still open at the bottom.
➡️ The #multicellular epithelium-like stage is shorter than we previously proposed.
#Actin accumulates at the furrow base before compartments fully seal ➡️ they're still open at the bottom.
➡️ The #multicellular epithelium-like stage is shorter than we previously proposed.
Using #UExM, we could finally see the MT network. Two populations:
Cortical MTs=from MTOCs to the cortex, spacing nuclei evenly
Furrow-tracking MTs=elongating with the ingressing membrane.
Cortical MTs=from MTOCs to the cortex, spacing nuclei evenly
Furrow-tracking MTs=elongating with the ingressing membrane.
February 17, 2026 at 1:02 PM
Using #UExM, we could finally see the MT network. Two populations:
Cortical MTs=from MTOCs to the cortex, spacing nuclei evenly
Furrow-tracking MTs=elongating with the ingressing membrane.
Cortical MTs=from MTOCs to the cortex, spacing nuclei evenly
Furrow-tracking MTs=elongating with the ingressing membrane.
Thx for @mollyherring.bsky.social for featuring our recent work with @centriolelab.bsky.social and our quest with @gautamdey.bsky.social & the support of the @moorefound.bsky.social to look for the beauty in every #eukaryote out there using #Expansion #Microscopy #UExM
Even with the largest zoom on a classic compound optical system, scientists struggle to make sense of finer details. Microbiologists are turning to an unexpected source to clear things up: a moisture-absorbing material found in diapers. www.quantamagazine.org/expansion-mi...
Expansion Microscopy Has Transformed How We See the Cellular World | Quanta Magazine
How physically magnifying objects using a key ingredient in diapers has opened an unprecedented view of the microbial world.
www.quantamagazine.org
February 4, 2026 at 7:30 PM
Thx for @mollyherring.bsky.social for featuring our recent work with @centriolelab.bsky.social and our quest with @gautamdey.bsky.social & the support of the @moorefound.bsky.social to look for the beauty in every #eukaryote out there using #Expansion #Microscopy #UExM
January 23, 2026 at 9:05 AM
#Microbial #Eukaryotes in #UExM on the cover of @natgenet.nature.com ! Unbelievable !!!
Also read the amazing work by @alexdemendoza.bsky.social and co !!!
Also read the amazing work by @alexdemendoza.bsky.social and co !!!
It is amazing that @dudinlab.bsky.social beautiful #ExM composition has been selected to highlight our #6mA work for the cover of @natgenet.nature.com. #Protists (and ichthyosporeans in particular) in the cover of NG must be quite unique!
December 11, 2025 at 12:04 PM
#Microbial #Eukaryotes in #UExM on the cover of @natgenet.nature.com ! Unbelievable !!!
Also read the amazing work by @alexdemendoza.bsky.social and co !!!
Also read the amazing work by @alexdemendoza.bsky.social and co !!!
So i'm usually interested about how cells divide in the cold, but couldnt resist helping out a tiny bit for a Euk dividing at 63°C.
Congrats to the whole team @hbrappap.bsky.social & Kudos to @fmikus.bsky.social for yet again the almighty #UExM !
Congrats to the whole team @hbrappap.bsky.social & Kudos to @fmikus.bsky.social for yet again the almighty #UExM !
So happy to announce our new preprint, “A geothermal amoeba sets a new upper temperature limit for eukaryotes.” We cultured a novel amoeba from Lassen Volcanic NP (CA, USA) that divides at 63°C (145°F) 🔥 - a new record for euk growth!
#protistsonsky 🧵
#protistsonsky 🧵
November 25, 2025 at 8:43 PM
So i'm usually interested about how cells divide in the cold, but couldnt resist helping out a tiny bit for a Euk dividing at 63°C.
Congrats to the whole team @hbrappap.bsky.social & Kudos to @fmikus.bsky.social for yet again the almighty #UExM !
Congrats to the whole team @hbrappap.bsky.social & Kudos to @fmikus.bsky.social for yet again the almighty #UExM !
I mean, how does Microtubules & centrin cytoskeleton shapes the suctorian resting and feeding tip ? Just how ?
#UExM #Expansion #Microscopy
#UExM #Expansion #Microscopy
Key transcripts encoded centrin-like proteins, a frequent component of sensory/contractile structures in protists. We visualized tentacle ultrastructure by U-ExM with @dudinlab.bsky.social lab, discovering stunning tip and collar structures 🤯that add structural complexity to new tentacle formation.
November 19, 2025 at 8:33 AM
I mean, how does Microtubules & centrin cytoskeleton shapes the suctorian resting and feeding tip ? Just how ?
#UExM #Expansion #Microscopy
#UExM #Expansion #Microscopy
@zjmaggiexu.bsky.social sent samples,fixed differently to see which can allow #UExM & Marine, our Lab Manager Extraordinaire,powered through. Its not the easiest sample, some protective layer hinders homogenous ExM of the cell body all the time,but the reaction we got when it worked was worth it n/2
November 18, 2025 at 5:19 PM
@zjmaggiexu.bsky.social sent samples,fixed differently to see which can allow #UExM & Marine, our Lab Manager Extraordinaire,powered through. Its not the easiest sample, some protective layer hinders homogenous ExM of the cell body all the time,but the reaction we got when it worked was worth it n/2
We’re not leaving our beloved #Ichthyosporeans ❤️ / they remain core. But this marks our first big step beyond them, using #UExM to explore how #multicellularity evolved across lineages; and using #Microscopy to see in 3D how cells organize, divide & come together. 🧫🌍
October 31, 2025 at 2:42 PM
We’re not leaving our beloved #Ichthyosporeans ❤️ / they remain core. But this marks our first big step beyond them, using #UExM to explore how #multicellularity evolved across lineages; and using #Microscopy to see in 3D how cells organize, divide & come together. 🧫🌍
A new #UExM probe for #Actin!
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
August 28, 2025 at 7:16 AM
A new #UExM probe for #Actin!
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !
Congrats to all !
If interested in #UExM, or #HAK-Actin, feel free to reach out !
Soon available at @spirochrome.com
#Expansion #Microscopy #ProtistsOnSky
Congrats to the whole team.
It was quite fun to teach @kristina-prokina.bsky.social how to #UExM
If i'm not mistaken, this would be the first intance of new species discription using some #UExM.
I know it won't be the last !
It was quite fun to teach @kristina-prokina.bsky.social how to #UExM
If i'm not mistaken, this would be the first intance of new species discription using some #UExM.
I know it won't be the last !
New paper is out! We have studied the cute tiny Discocelia plataet sp. n. to obtain the first molecular data of the order Discocelida and clarify its cell structure. All this for a better understanding of the evolution of Cercozoa.
onlinelibrary.wiley.com/doi/epdf/10....
onlinelibrary.wiley.com/doi/epdf/10....
August 26, 2025 at 5:39 PM
Congrats to the whole team.
It was quite fun to teach @kristina-prokina.bsky.social how to #UExM
If i'm not mistaken, this would be the first intance of new species discription using some #UExM.
I know it won't be the last !
It was quite fun to teach @kristina-prokina.bsky.social how to #UExM
If i'm not mistaken, this would be the first intance of new species discription using some #UExM.
I know it won't be the last !