We're celebrating the Postdoc Appreciation Week 2026 with the event: "Research road bumps? You are not alone."
Come and join us on Tue, 22 Sep, 10-12h at IMB Mainz.
Register here: www.imb.de/seminars-mee...
We're celebrating the Postdoc Appreciation Week 2026 with the event: "Research road bumps? You are not alone."
Come and join us on Tue, 22 Sep, 10-12h at IMB Mainz.
Register here: www.imb.de/seminars-mee...
Happy to share the Krämer lab's new paper titled:
"Mitochondrial checkpoint for interferon responses in macrophages."
🔎Read it here: www.explorationpub.com/Journals/eta...
Happy to share the Krämer lab's new paper titled:
"Mitochondrial checkpoint for interferon responses in macrophages."
🔎Read it here: www.explorationpub.com/Journals/eta...
I’m proud to see how the work of several students in my group has come together in this article.
@imbmainz.bsky.social @sfb1361.bsky.social
Happy to share the Luck lab's latest work covering
"Variant characterization in the intrinsically disordered human proteome"
🔎Check out the details: www.nature.com/articles/s41...
Https://rdcu.be/fw2oz
Dx.doi.org/10.1038/s41594-026-01846-z
Happy to share the Luck lab's latest work covering
"Variant characterization in the intrinsically disordered human proteome"
🔎Check out the details: www.nature.com/articles/s41...
The article explores mechanisms of MCM2–7 helicase activation and initial DNA melting at near base-pair resolution.
🔎Find out more: www.nature.com/articles/s41...
Amazing work - Congratulations! 🎊🎉
We map the earliest DNA strand separation during MCM2-7 helicase activation at near base-pair resolution, revealing where origin melting begins and how DNA is routed through the Mcm2/5 gate.
doi.org/10.1038/s414...
#DNAReplication
The article explores mechanisms of MCM2–7 helicase activation and initial DNA melting at near base-pair resolution.
🔎Find out more: www.nature.com/articles/s41...
Amazing work - Congratulations! 🎊🎉
Congrats to the Krämer lab on their latest work:
"Identification of dual-targeting PROTACs for ataxia telangiectasia and RAD3-related and aurora kinase A as chemo-sensitizers for leukemia cells."
🔎Read the article here: www.sciencedirect.com/science/arti...
Congrats to the Krämer lab on their latest work:
"Identification of dual-targeting PROTACs for ataxia telangiectasia and RAD3-related and aurora kinase A as chemo-sensitizers for leukemia cells."
🔎Read the article here: www.sciencedirect.com/science/arti...
Happy to share the Carell lab's latest work covering
"Increasing TET Expression and 5-Hydroxymethylcytosine Formation by a Carbocyclic 5-Aza-2′-deoxy-cytidine Antimetabolite"
🏊Dive into the details: doi.org/10.1002/anie...
#SFB1361
Happy to share the Carell lab's latest work covering
"Increasing TET Expression and 5-Hydroxymethylcytosine Formation by a Carbocyclic 5-Aza-2′-deoxy-cytidine Antimetabolite"
🏊Dive into the details: doi.org/10.1002/anie...
#SFB1361
Great to see the programmes unite to spark curiosity about DNA in young students!🧬
Thanks to the great team from the König and @zarnack-group.bsky.social labs at @uni-wuerzburg.de! #MissionDNA
Great to see the programmes unite to spark curiosity about DNA in young students!🧬
Happy to share the new review by the Cardoso lab (@cardosolab.bsky.social) covering
"Spatial organization and dynamics of genome replication: from forks to foci"
🔎Read it here: doi.org/10.1093/nar/...
Congratulations on the great work! 🎊
#SFB1361
We connect the two halves of the DNA replication field — single-cell microscopy and genome-wide sequencing to show how each method’s strengths build one picture: from DNA fibers → replication foci → origin & timing maps.
🔗 doi.org/10.1093/nar/gkag550
@narjournal.bsky.social
Happy to share the new review by the Cardoso lab (@cardosolab.bsky.social) covering
"Spatial organization and dynamics of genome replication: from forks to foci"
🔎Read it here: doi.org/10.1093/nar/...
Congratulations on the great work! 🎊
#SFB1361
Congrats to the Krämer lab on their new publication titled
"Dual FLT3/MAPK14 Proteolysis-Targeting Chimera (PROTAC) Induces Potent Acute Myeloid Leukemia Cell Death"
🔎Find out more: doi.org/10.3390/ph19...
#SFB1361
Congrats to the Krämer lab on their new publication titled
"Dual FLT3/MAPK14 Proteolysis-Targeting Chimera (PROTAC) Induces Potent Acute Myeloid Leukemia Cell Death"
🔎Find out more: doi.org/10.3390/ph19...
#SFB1361
Join us at IMB Mainz from 04–06 November 2026 for the “RNase H 2026”, organized by 4R RTG and IMB Mainz. Don't miss this conference and register now via: 4r-rtg.de/rnase-h-2026/
#IMB #RNASEH2026 #4R-RTG
Join us at IMB Mainz from 04–06 November 2026 for the “RNase H 2026”, organized by 4R RTG and IMB Mainz. Don't miss this conference and register now via: 4r-rtg.de/rnase-h-2026/
#IMB #RNASEH2026 #4R-RTG
#ERCAdG #SFB1361 #Science
"Dual inhibition of PP2A and WEE1 induces apoptosis and mitotic catastrophe in cancer cells"
🔎Read the full paper here: www.sciencedirect.com/science/arti...
"Dual inhibition of PP2A and WEE1 induces apoptosis and mitotic catastrophe in cancer cells"
🔎Read the full paper here: www.sciencedirect.com/science/arti...
Congrats to the Carell lab on their latest work!
The article focuses on structural and biochemical characterization of yeast Tcd enzymes installing the post-transcriptional modification ct6A in tRNA.
Find out more here: academic.oup.com/nar/article/...
Congrats to the Carell lab on their latest work!
The article focuses on structural and biochemical characterization of yeast Tcd enzymes installing the post-transcriptional modification ct6A in tRNA.
Find out more here: academic.oup.com/nar/article/...
“The Evil Within: Regulation and Repair of Endogenous DNA Damage” explored how cells detect, respond to & repair internal genetic threats.🧬
It was great seeing you all!
@imbmainz.bsky.social #ISC26DNArepair
“The Evil Within: Regulation and Repair of Endogenous DNA Damage” explored how cells detect, respond to & repair internal genetic threats.🧬
It was great seeing you all!
@imbmainz.bsky.social #ISC26DNArepair
Congrats to the Hofmann lab on their new article exploring how Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model.
🔎Read more here: www.nature.com/articles/s41...
Congrats to the Hofmann lab on their new article exploring how Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model.
🔎Read more here: www.nature.com/articles/s41...
Our students showcased their poster presentation and were thrilled to receive the prestigious best poster prize. Congratulations to all of them! 🎉
@imbmainz.bsky.social
Our students showcased their poster presentation and were thrilled to receive the prestigious best poster prize. Congratulations to all of them! 🎉
@imbmainz.bsky.social
Congratulations to the Hopfner lab (@hopfnerlab.bsky.social) on their new publication:
"Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex"
🔎Find out more here: doi.org/10.1093/nar/...
Congratulations to the Hopfner lab (@hopfnerlab.bsky.social) on their new publication:
"Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex"
🔎Find out more here: doi.org/10.1093/nar/...
Happy to share the new joint publication by our #SFB1361 PI's Julian Stingele (@jstingele.bsky.social) and Petra Beli,
covering how RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response.
Read more here: www.sciencedirect.com/science/arti...
Happy to share the new joint publication by our #SFB1361 PI's Julian Stingele (@jstingele.bsky.social) and Petra Beli,
covering how RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response.
Read more here: www.sciencedirect.com/science/arti...
#ISC26DNArepair
#ISC26DNArepair
Congrats to the Carell lab on their new paper:
"One-Step and universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U"
🔎Read more here: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Congrats to the Carell lab on their new paper:
"One-Step and universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U"
🔎Read more here: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Congrats to the @dikiclab.bsky.social and Beli labs on their joint #SFB1361 publication, covering how DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality.
🔎Read the paper here: www.science.org/doi/10.1126/...
Congrats to the @dikiclab.bsky.social and Beli labs on their joint #SFB1361 publication, covering how DNA-protein cross-links promote cGAS-STING-driven premature aging and embryonic lethality.
🔎Read the paper here: www.science.org/doi/10.1126/...
Join us to connect, discuss and collaborate!
Details & registration: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
Join us to connect, discuss and collaborate!
Details & registration: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
Dive into details at @imbmainz.bsky.social in Mainz this 10-13 March 2026!
Register now: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
Dive into details at @imbmainz.bsky.social in Mainz this 10-13 March 2026!
Register now: www.sfb1361.de/dnarepairconf2026
#SFB1361 #IMBMainz #ISC26DNArepair
We're happy to share a new preprint from our associated member, Dr Maximilian Reuter (@reuterlm.bsky.social), on
"Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution"
🔎Read more here: www.biorxiv.org/content/10.6...
We're happy to share a new preprint from our associated member, Dr Maximilian Reuter (@reuterlm.bsky.social), on
"Mechanisms of MCM2-7 helicase activation and initial DNA melting at near base-pair resolution"
🔎Read more here: www.biorxiv.org/content/10.6...