Centro de Biologia Molecular Severo Ochoa is hiring:
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
October 28, 2026 at 10:30 AM
Centro de Biologia Molecular Severo Ochoa is hiring:
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
Centro de Biologia Molecular Severo Ochoa is hiring:
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
October 28, 2026 at 10:30 AM
Centro de Biologia Molecular Severo Ochoa is hiring:
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
Postdoctoral Candidate Juan de la Cierva
#postdoc #dnareplication #ubiquitinpathway
🆕 ADVANCE ONLINE 🆕
RESEARCH COMMUNICATION: MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation
By Bektash et al. and Masato Kanemaki
➡️ https://ow.ly/3QFg50ZXOwN
#DNA #DNAreplication #helicase
RESEARCH COMMUNICATION: MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation
By Bektash et al. and Masato Kanemaki
➡️ https://ow.ly/3QFg50ZXOwN
#DNA #DNAreplication #helicase
October 26, 2026 at 3:00 PM
🆕 ADVANCE ONLINE 🆕
RESEARCH COMMUNICATION: MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation
By Bektash et al. and Masato Kanemaki
➡️ https://ow.ly/3QFg50ZXOwN
#DNA #DNAreplication #helicase
RESEARCH COMMUNICATION: MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation
By Bektash et al. and Masato Kanemaki
➡️ https://ow.ly/3QFg50ZXOwN
#DNA #DNAreplication #helicase
Remarkably, structurally distinct helicase loaders target the same opening interface in DnaB.
Different evolutionary solutions, a shared molecular strategy.
Huge thanks to Lidia Araújo-Bazán and everyone who contributed!
📄 academic.oup.com/nar/article/...
#CryoEM #DNAReplication
Different evolutionary solutions, a shared molecular strategy.
Huge thanks to Lidia Araújo-Bazán and everyone who contributed!
📄 academic.oup.com/nar/article/...
#CryoEM #DNAReplication
October 26, 2026 at 10:10 AM
Remarkably, structurally distinct helicase loaders target the same opening interface in DnaB.
Different evolutionary solutions, a shared molecular strategy.
Huge thanks to Lidia Araújo-Bazán and everyone who contributed!
📄 academic.oup.com/nar/article/...
#CryoEM #DNAReplication
Different evolutionary solutions, a shared molecular strategy.
Huge thanks to Lidia Araújo-Bazán and everyone who contributed!
📄 academic.oup.com/nar/article/...
#CryoEM #DNAReplication
Fully-funded 4-year #PhD project with @Conrad Nieduszynski at Earlham Institute, using genome language models and high-throughput testing to decode #DNAreplication regulation.
📅 Applications close: 30 November 2026
📅 Applications close: 30 November 2026
Decoding and designing DNA replication origins using genome language models
How does a cell know where and when to copy its DNA? And can we use artificial intelligence to design entirely new genetic elements that control this process? This exciting interdisciplinary PhD project will tackle a fundamental question in biology: how DNA replication origins are encoded and regulated within genomes.
okt.to
October 26, 2026 at 7:00 AM
Fully-funded 4-year #PhD project with @Conrad Nieduszynski at Earlham Institute, using genome language models and high-throughput testing to decode #DNAreplication regulation.
📅 Applications close: 30 November 2026
📅 Applications close: 30 November 2026
Projects include:
- #engineeringbiology for future crops
- developing trustworthy #AI for predictive models
- understanding origins of #DNAreplication
- #singlecell genomics of #protists
Visit our website to find out more!
- #engineeringbiology for future crops
- developing trustworthy #AI for predictive models
- understanding origins of #DNAreplication
- #singlecell genomics of #protists
Visit our website to find out more!
October 20, 2026 at 12:36 PM
Projects include:
- #engineeringbiology for future crops
- developing trustworthy #AI for predictive models
- understanding origins of #DNAreplication
- #singlecell genomics of #protists
Visit our website to find out more!
- #engineeringbiology for future crops
- developing trustworthy #AI for predictive models
- understanding origins of #DNAreplication
- #singlecell genomics of #protists
Visit our website to find out more!
🧬 How do cells ensure their DNA is copied completely and accurately before division? The Boos Lab at @imprs-lm.bsky.social is recruiting a PhD student to study the molecular control of replication origin firing — a key process for maintaining genome stability. Apply now!
#DNAReplication #CellCycle
#DNAReplication #CellCycle
September 25, 2026 at 4:09 PM
🧬 How do cells ensure their DNA is copied completely and accurately before division? The Boos Lab at @imprs-lm.bsky.social is recruiting a PhD student to study the molecular control of replication origin firing — a key process for maintaining genome stability. Apply now!
#DNAReplication #CellCycle
#DNAReplication #CellCycle
We're so glad to hear our content brought more joy to #SCLAmbassador Minu's classroom. If you haven't already, make sure to check out her lesson plan on #DNAreplication with Meselon and Stahl's famous experiment: bit.ly/sclminu
Stay tuned next week to meet our 2026 #SCLAmbassadors!
Stay tuned next week to meet our 2026 #SCLAmbassadors!
February 5, 2026 at 1:00 PM
We're so glad to hear our content brought more joy to #SCLAmbassador Minu's classroom. If you haven't already, make sure to check out her lesson plan on #DNAreplication with Meselon and Stahl's famous experiment: bit.ly/sclminu
Stay tuned next week to meet our 2026 #SCLAmbassadors!
Stay tuned next week to meet our 2026 #SCLAmbassadors!
🧬 Delighted to share our new Nature Communications paper! We show how MCM2-7 double hexamers become active helicases and trigger DNA melting in vivo. Led by Chris Weekes & L. Maximilian Reuter. Congratulations to the whole team!
doi.org/10.1038/s414...
#DNAReplication
doi.org/10.1038/s414...
#DNAReplication
Mechanisms of MCM2–7 helicase activation and initial DNA melting at near base-pair resolution - Nature Communications
DNA replication begins when inactive helicases are switched on to unwind DNA. Here, the authors map this activation in yeast, revealing where DNA first melts and how helicase splitting, factor release...
doi.org
July 28, 2026 at 10:24 AM
🧬 Delighted to share our new Nature Communications paper! We show how MCM2-7 double hexamers become active helicases and trigger DNA melting in vivo. Led by Chris Weekes & L. Maximilian Reuter. Congratulations to the whole team!
doi.org/10.1038/s414...
#DNAReplication
doi.org/10.1038/s414...
#DNAReplication
📢 One more week to go... exciting fully funded #PhD position for UK candidates to work across #ICR and #Imperial on novel mechanisms in genome stability and #CancerResearch.
#PhDStudentship #LifeSciences #DNAReplication #CRISPR
#PhDStudentship #LifeSciences #DNAReplication #CRISPR
We are recruiting a PhD student to tackle a fundamental question in cancer biology: how DNA replication fails at centromeres and drives chromosomal instability (CIN) — a major driver of tumour evolution and therapy resistance.
tiny.cc/vilw001
#PhD #CancerResearch #GenomeStability #Chromatin
tiny.cc/vilw001
#PhD #CancerResearch #GenomeStability #Chromatin
PhD Studentship: Understanding How Centromere Replication Fails in Cancer Imperial College London & The Institute of Cancer Research (CRUK Convergence Science Centre) at Institute of Cancer Research o...
PhD Project - PhD Studentship: Understanding How Centromere Replication Fails in Cancer Imperial College London & The Institute of Cancer Research (CRUK Convergence Science Centre) at Institute of...
www.findaphd.com
January 19, 2026 at 1:57 PM
📢 One more week to go... exciting fully funded #PhD position for UK candidates to work across #ICR and #Imperial on novel mechanisms in genome stability and #CancerResearch.
#PhDStudentship #LifeSciences #DNAReplication #CRISPR
#PhDStudentship #LifeSciences #DNAReplication #CRISPR
#DNAReplication Q:
1) Why does DNA Primase make RNA primers?
2) Why can't DNA Polymerase start a DNA chain?
Both facts seems quite inefficient, is it a relic from RNA world?
#phdlife #phdchat #phdvoice
1) Why does DNA Primase make RNA primers?
2) Why can't DNA Polymerase start a DNA chain?
Both facts seems quite inefficient, is it a relic from RNA world?
#phdlife #phdchat #phdvoice
October 13, 2025 at 8:48 PM
#DNAReplication Q:
1) Why does DNA Primase make RNA primers?
2) Why can't DNA Polymerase start a DNA chain?
Both facts seems quite inefficient, is it a relic from RNA world?
#phdlife #phdchat #phdvoice
1) Why does DNA Primase make RNA primers?
2) Why can't DNA Polymerase start a DNA chain?
Both facts seems quite inefficient, is it a relic from RNA world?
#phdlife #phdchat #phdvoice
Great #EMBOdnatopology meeting in Szklarska Poręba: exciting science, inspiring discussions, and pleased to share our #DNAreplication work! Thanks to Dagmara Jakimowicz, Marcin Szafran & organizers! @embo.org
September 18, 2025 at 5:50 AM
Great #EMBOdnatopology meeting in Szklarska Poręba: exciting science, inspiring discussions, and pleased to share our #DNAreplication work! Thanks to Dagmara Jakimowicz, Marcin Szafran & organizers! @embo.org
Learn all about #genetics with our convenient & discounted bundle! Cover #transcription, #translation, #proteinsynthesis #DNAreplication, #PCR & more! Details are here: buff.ly/4xXq8Su
#EduSky #iteachbio #DNA #biologyteacher
#EduSky #iteachbio #DNA #biologyteacher
January 18, 2026 at 11:59 AM
Learn all about #genetics with our convenient & discounted bundle! Cover #transcription, #translation, #proteinsynthesis #DNAreplication, #PCR & more! Details are here: buff.ly/4xXq8Su
#EduSky #iteachbio #DNA #biologyteacher
#EduSky #iteachbio #DNA #biologyteacher
Did you know it takes a human cell only 8 hours to replicate 3 BILLION base pairs of DNA for cell division? Unbelievable. Learn how it happens with our DNA Replication paper model! Find out more here: buff.ly/rJStomA
#EduSky #DNA #DNAreplication #celldivision #mitosis #iteachbio #biologyteacher
#EduSky #DNA #DNAreplication #celldivision #mitosis #iteachbio #biologyteacher
January 9, 2026 at 11:06 AM
Did you know it takes a human cell only 8 hours to replicate 3 BILLION base pairs of DNA for cell division? Unbelievable. Learn how it happens with our DNA Replication paper model! Find out more here: buff.ly/rJStomA
#EduSky #DNA #DNAreplication #celldivision #mitosis #iteachbio #biologyteacher
#EduSky #DNA #DNAreplication #celldivision #mitosis #iteachbio #biologyteacher
Did you know that the 3 billion base pairs of DNA in human cells is copied in about 8 hours? But how? Our DNA Replication paper model shows you how!
Find out more here: buff.ly/a036Nj3
#EduSky #DNAreplication #DNApolymerase #helicase #primase #iteachbio #biologyteacher #genetics #DNA #celldivision
Find out more here: buff.ly/a036Nj3
#EduSky #DNAreplication #DNApolymerase #helicase #primase #iteachbio #biologyteacher #genetics #DNA #celldivision
November 25, 2025 at 12:00 PM
Did you know that the 3 billion base pairs of DNA in human cells is copied in about 8 hours? But how? Our DNA Replication paper model shows you how!
Find out more here: buff.ly/a036Nj3
#EduSky #DNAreplication #DNApolymerase #helicase #primase #iteachbio #biologyteacher #genetics #DNA #celldivision
Find out more here: buff.ly/a036Nj3
#EduSky #DNAreplication #DNApolymerase #helicase #primase #iteachbio #biologyteacher #genetics #DNA #celldivision
DNA is amazing. Show your students how #DNA is copied in cells with our DNA Replication model then compare it with our #PCR model! Find out more here:
DNA Replication: buff.ly/iYtYbP6
PCR: buff.ly/ZEyXZx6
#EduSky #genetics #DNAreplication #iteachbio
DNA Replication: buff.ly/iYtYbP6
PCR: buff.ly/ZEyXZx6
#EduSky #genetics #DNAreplication #iteachbio
July 21, 2025 at 9:11 AM
DNA is amazing. Show your students how #DNA is copied in cells with our DNA Replication model then compare it with our #PCR model! Find out more here:
DNA Replication: buff.ly/iYtYbP6
PCR: buff.ly/ZEyXZx6
#EduSky #genetics #DNAreplication #iteachbio
DNA Replication: buff.ly/iYtYbP6
PCR: buff.ly/ZEyXZx6
#EduSky #genetics #DNAreplication #iteachbio
How are 3 billion base pairs of DNA copied each time one of your cells divides? Our DNA Replication paper model shows you how! Learn more here: bit.ly/2Nx1txR
#EduSky #iteachbio #DNA #DNAreplication #genetics #biologyteacher
#EduSky #iteachbio #DNA #DNAreplication #genetics #biologyteacher
April 21, 2025 at 7:01 PM
How are 3 billion base pairs of DNA copied each time one of your cells divides? Our DNA Replication paper model shows you how! Learn more here: bit.ly/2Nx1txR
#EduSky #iteachbio #DNA #DNAreplication #genetics #biologyteacher
#EduSky #iteachbio #DNA #DNAreplication #genetics #biologyteacher
Help your students understand how DNA replication happens with our paper model! The differences between leading & lagging strands becomes obvious! Click here for details: https://bit.ly/2Nx1txR
#EduSky #DNA #DNAreplication #iteachbio #genetics
#EduSky #DNA #DNAreplication #iteachbio #genetics
January 14, 2025 at 1:26 PM
Help your students understand how DNA replication happens with our paper model! The differences between leading & lagging strands becomes obvious! Click here for details: https://bit.ly/2Nx1txR
#EduSky #DNA #DNAreplication #iteachbio #genetics
#EduSky #DNA #DNAreplication #iteachbio #genetics
OUTLOOK: A new perspective on ATR's role in translesion synthesis
By Laura Lindsey-Boltz and Aziz Sancar
➡️ https://genesdev.cshlp.org/content/40/13-14/979.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UNC Biochemistry and Biophysics department
#DNAreplication
By Laura Lindsey-Boltz and Aziz Sancar
➡️ https://genesdev.cshlp.org/content/40/13-14/979.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UNC Biochemistry and Biophysics department
#DNAreplication
July 17, 2026 at 6:00 PM
OUTLOOK: A new perspective on ATR's role in translesion synthesis
By Laura Lindsey-Boltz and Aziz Sancar
➡️ https://genesdev.cshlp.org/content/40/13-14/979.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UNC Biochemistry and Biophysics department
#DNAreplication
By Laura Lindsey-Boltz and Aziz Sancar
➡️ https://genesdev.cshlp.org/content/40/13-14/979.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UNC Biochemistry and Biophysics department
#DNAreplication
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UTMB Health
#DNAreplication #DNArepair #genomestability #translesionsynthesis
By Yoon et al. and Satya Prakash
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UTMB Health
#DNAreplication #DNArepair #genomestability #translesionsynthesis
July 9, 2026 at 6:00 PM
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UTMB Health
#DNAreplication #DNArepair #genomestability #translesionsynthesis
By Yoon et al. and Satya Prakash
➡️ https://genesdev.cshlp.org/content/40/13-14/1059.abstract
UTMB Health
#DNAreplication #DNArepair #genomestability #translesionsynthesis
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://ow.ly/l24j50Z5LM6
UTMB Health
#DNAreplication #translesionsynthesis #genomestability #DNArepair
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://ow.ly/l24j50Z5LM6
UTMB Health
#DNAreplication #translesionsynthesis #genomestability #DNArepair
June 2, 2026 at 3:00 PM
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://ow.ly/l24j50Z5LM6
UTMB Health
#DNAreplication #translesionsynthesis #genomestability #DNArepair
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://ow.ly/l24j50Z5LM6
UTMB Health
#DNAreplication #translesionsynthesis #genomestability #DNArepair
SYMPOSIUM OUTLOOK: #Telomeres at the nexus of #aging, #tumor suppression, and #inflammation: toward an understanding beyond #senescence
By Samuel Bloom & Jan Karlseder
➡️ https://bit.ly/410dJwg
##cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer
By Samuel Bloom & Jan Karlseder
➡️ https://bit.ly/410dJwg
##cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer
August 20, 2025 at 2:31 PM
SYMPOSIUM OUTLOOK: #Telomeres at the nexus of #aging, #tumor suppression, and #inflammation: toward an understanding beyond #senescence
By Samuel Bloom & Jan Karlseder
➡️ https://bit.ly/410dJwg
##cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer
By Samuel Bloom & Jan Karlseder
➡️ https://bit.ly/410dJwg
##cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer
My lab is #hiring!
I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.
www.jobs.ac.uk/job/DLO693/r...
www.jobs.ac.uk/job/DLP016/r...
#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS
I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.
www.jobs.ac.uk/job/DLO693/r...
www.jobs.ac.uk/job/DLP016/r...
#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS
Research Fellow at University of Birmingham
Discover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
www.jobs.ac.uk
January 31, 2025 at 10:01 AM
My lab is #hiring!
I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.
www.jobs.ac.uk/job/DLO693/r...
www.jobs.ac.uk/job/DLP016/r...
#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS
I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.
www.jobs.ac.uk/job/DLO693/r...
www.jobs.ac.uk/job/DLP016/r...
#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS
Registration open!
Led by our #DNAReplication Group, this online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬💻
🗓️ 13-14 May 2026
📍 Online (via Zoom)
👉 buff.ly/3ac0FPQ
Image: @nanoporetech.com
Led by our #DNAReplication Group, this online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬💻
🗓️ 13-14 May 2026
📍 Online (via Zoom)
👉 buff.ly/3ac0FPQ
Image: @nanoporetech.com
Detection of DNA base modification using nanopore sequencing 2026
In this comprehensive two-day course, participants will learn how to use nanopore sequencing to detect DNA base modifications.
buff.ly
February 6, 2026 at 4:04 PM
Registration open!
Led by our #DNAReplication Group, this online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬💻
🗓️ 13-14 May 2026
📍 Online (via Zoom)
👉 buff.ly/3ac0FPQ
Image: @nanoporetech.com
Led by our #DNAReplication Group, this online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬💻
🗓️ 13-14 May 2026
📍 Online (via Zoom)
👉 buff.ly/3ac0FPQ
Image: @nanoporetech.com
Registration open! Led by our #DNAReplication Group, the online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬
🗓️ 13-14 May 2026
📍 Online (via Zoom)
@nanoporetech.com
🗓️ 13-14 May 2026
📍 Online (via Zoom)
@nanoporetech.com
Detection of DNA base modification using nanopore sequencing 2026
In this comprehensive two-day course, participants will learn how to use nanopore sequencing to detect DNA base modifications.
buff.ly
December 28, 2025 at 1:01 PM
Registration open! Led by our #DNAReplication Group, the online course covers principles and practice of modified base detection, visualisation, and experimental considerations for ultra long #sequencing reads. 🧬
🗓️ 13-14 May 2026
📍 Online (via Zoom)
@nanoporetech.com
🗓️ 13-14 May 2026
📍 Online (via Zoom)
@nanoporetech.com