Follow @biohackingpathway for more
#aging #DNAdamage #cellularstress #health #science #research #longevity #miceexperiments #biologicalaging #wellnesslife #wellnesshotel #wellbeingjourney #wellbeingwarrior #antiaging
#aging #DNAdamage #cellularstress #health #science #research #longevity #miceexperiments #biologicalaging #wellnesslife #wellnesshotel #wellbeingjourney #wellbeingwarrior #antiaging
July 8, 2026 at 11:07 PM
Follow @biohackingpathway for more
#aging #DNAdamage #cellularstress #health #science #research #longevity #miceexperiments #biologicalaging #wellnesslife #wellnesshotel #wellbeingjourney #wellbeingwarrior #antiaging
#aging #DNAdamage #cellularstress #health #science #research #longevity #miceexperiments #biologicalaging #wellnesslife #wellnesshotel #wellbeingjourney #wellbeingwarrior #antiaging
Excited to share our latest study in Nature Communications ✨
We map how cells clear DNA damage–stalled RNA polymerase II using a stepwise TFIIH → ubiquitin/VCP mechanism, keeping transcription and genome stability on track.
Paper: www.nature.com/articles/s41...
#Genomics #DNADamage #CellBiology
We map how cells clear DNA damage–stalled RNA polymerase II using a stepwise TFIIH → ubiquitin/VCP mechanism, keeping transcription and genome stability on track.
Paper: www.nature.com/articles/s41...
#Genomics #DNADamage #CellBiology
February 13, 2026 at 6:22 PM
Excited to share our latest study in Nature Communications ✨
We map how cells clear DNA damage–stalled RNA polymerase II using a stepwise TFIIH → ubiquitin/VCP mechanism, keeping transcription and genome stability on track.
Paper: www.nature.com/articles/s41...
#Genomics #DNADamage #CellBiology
We map how cells clear DNA damage–stalled RNA polymerase II using a stepwise TFIIH → ubiquitin/VCP mechanism, keeping transcription and genome stability on track.
Paper: www.nature.com/articles/s41...
#Genomics #DNADamage #CellBiology
#MedSky🧪 #IDsky #ImmunoSky #NeuroSky #Drugdevelopment #Drugdiscovery Age & disease-associated stressors that drive inflammation, reactive oxygen species, toxic protein accumulation, metabolic dysregulation or #DNAdamage may cause #senescence in many cell types, incl neurons .
November 15, 2024 at 7:22 AM
#MedSky🧪 #IDsky #ImmunoSky #NeuroSky #Drugdevelopment #Drugdiscovery Age & disease-associated stressors that drive inflammation, reactive oxygen species, toxic protein accumulation, metabolic dysregulation or #DNAdamage may cause #senescence in many cell types, incl neurons .
📢We are pleased to welcome Tereza Kratochvílová to our team. She will be Eva's @evadt.bsky.social first Ph.D. student, working primarily on the role of SUMO signaling in DNA damage sites. 🧬
We hope Tereza enjoys her time here and does well.
#PhD #SUMO #DNAdamage #Arabidopsis
We hope Tereza enjoys her time here and does well.
#PhD #SUMO #DNAdamage #Arabidopsis
May 27, 2026 at 6:28 AM
📢We are pleased to welcome Tereza Kratochvílová to our team. She will be Eva's @evadt.bsky.social first Ph.D. student, working primarily on the role of SUMO signaling in DNA damage sites. 🧬
We hope Tereza enjoys her time here and does well.
#PhD #SUMO #DNAdamage #Arabidopsis
We hope Tereza enjoys her time here and does well.
#PhD #SUMO #DNAdamage #Arabidopsis
Thrilled to share that the ETH Laboratory of Toxicology is now LIVE on BlueSky! Follow @sturlalab.bsky.social for updates on 🦠 #microbiome #science, 💻 #bioinformatics, 🧬 #dnadamage, and of course 🧪 #oncology.
Also: sneek peeks into our 🇨🇭 Swiss life and fun!
Also: sneek peeks into our 🇨🇭 Swiss life and fun!
November 20, 2024 at 5:02 PM
Thrilled to share that the ETH Laboratory of Toxicology is now LIVE on BlueSky! Follow @sturlalab.bsky.social for updates on 🦠 #microbiome #science, 💻 #bioinformatics, 🧬 #dnadamage, and of course 🧪 #oncology.
Also: sneek peeks into our 🇨🇭 Swiss life and fun!
Also: sneek peeks into our 🇨🇭 Swiss life and fun!
Moonjung Jung, Jungwoo Kim, Agata Smogorzewska @rockefelleruniv.bsky.social and colleagues show that combined ALDH9A1 and FANCD2 deficiency leads to genomic instability, decreased cell survival, and tumorigenesis. rupress.org/jcb/article/...
#DNADamage #FanconiAnemia
#DNADamage #FanconiAnemia
June 20, 2025 at 4:08 PM
Moonjung Jung, Jungwoo Kim, Agata Smogorzewska @rockefelleruniv.bsky.social and colleagues show that combined ALDH9A1 and FANCD2 deficiency leads to genomic instability, decreased cell survival, and tumorigenesis. rupress.org/jcb/article/...
#DNADamage #FanconiAnemia
#DNADamage #FanconiAnemia
On our way to the “From Genome Instability to Cancer A Tribute to Angelos Constantinou” meeting in beautiful Carry-Le-Rouet 🇫🇷
Looking forward to learning more on all things #DNAdamage/repair/integrity and stay tuned for Giovanni’s talk!
www.tribute2angelos.fr/page/home/
Looking forward to learning more on all things #DNAdamage/repair/integrity and stay tuned for Giovanni’s talk!
www.tribute2angelos.fr/page/home/
March 10, 2025 at 9:45 AM
On our way to the “From Genome Instability to Cancer A Tribute to Angelos Constantinou” meeting in beautiful Carry-Le-Rouet 🇫🇷
Looking forward to learning more on all things #DNAdamage/repair/integrity and stay tuned for Giovanni’s talk!
www.tribute2angelos.fr/page/home/
Looking forward to learning more on all things #DNAdamage/repair/integrity and stay tuned for Giovanni’s talk!
www.tribute2angelos.fr/page/home/
Experimental drug repairs DNA damage caused by common diseases
medicalxpress.com/news/2025-12... #medsky #dna #dnadamage
medicalxpress.com/news/2025-12... #medsky #dna #dnadamage
a computer screen shows a glowing dna molecule
ALT: a computer screen shows a glowing dna molecule
media.tenor.com
December 4, 2025 at 7:50 PM
Experimental drug repairs DNA damage caused by common diseases
medicalxpress.com/news/2025-12... #medsky #dna #dnadamage
medicalxpress.com/news/2025-12... #medsky #dna #dnadamage
ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the #FanconiAnemia pathway. From Moonjung Jung, Jungwoo Kim, Agata Smogorzewska @rockefelleruniv.bsky.social and colleagues: rupress.org/jcb/article/...
#CellMetabolism #DNAbiology #Disease #Genetics #DNADamage
#CellMetabolism #DNAbiology #Disease #Genetics #DNADamage
June 27, 2025 at 2:35 PM
ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the #FanconiAnemia pathway. From Moonjung Jung, Jungwoo Kim, Agata Smogorzewska @rockefelleruniv.bsky.social and colleagues: rupress.org/jcb/article/...
#CellMetabolism #DNAbiology #Disease #Genetics #DNADamage
#CellMetabolism #DNAbiology #Disease #Genetics #DNADamage
📅 The Evil Within: Regulation and Repair of Endogenous DNA Damage conference is coming to @imbmainz.bsky.social, Germany on March 10–13, 2026.
Registration opens late summer 2025!
Follow @sfb1361.bsky.social for updates.
#ISC26DNArepair #DNARepair #DNADamage
Registration opens late summer 2025!
Follow @sfb1361.bsky.social for updates.
#ISC26DNArepair #DNARepair #DNADamage
March 17, 2025 at 11:41 AM
📅 The Evil Within: Regulation and Repair of Endogenous DNA Damage conference is coming to @imbmainz.bsky.social, Germany on March 10–13, 2026.
Registration opens late summer 2025!
Follow @sfb1361.bsky.social for updates.
#ISC26DNArepair #DNARepair #DNADamage
Registration opens late summer 2025!
Follow @sfb1361.bsky.social for updates.
#ISC26DNArepair #DNARepair #DNADamage
📝 Online now - the Feature Review "Transactions on micronuclear DNA and implications for immune signaling" from @johnmaciejowski.bsky.social and Roger Greenberg.
#Micronuclei #NuclearEnvelope #EnvelopeRupture #DNAdamage #ImmuneResponse
Read it here: authors.elsevier.com/a/1m8Ps3S6Gf...
#Micronuclei #NuclearEnvelope #EnvelopeRupture #DNAdamage #ImmuneResponse
Read it here: authors.elsevier.com/a/1m8Ps3S6Gf...
November 24, 2025 at 7:34 PM
📝 Online now - the Feature Review "Transactions on micronuclear DNA and implications for immune signaling" from @johnmaciejowski.bsky.social and Roger Greenberg.
#Micronuclei #NuclearEnvelope #EnvelopeRupture #DNAdamage #ImmuneResponse
Read it here: authors.elsevier.com/a/1m8Ps3S6Gf...
#Micronuclei #NuclearEnvelope #EnvelopeRupture #DNAdamage #ImmuneResponse
Read it here: authors.elsevier.com/a/1m8Ps3S6Gf...
Remembering Kendric Smith, A Pioneer in Radiation Oncology and Photobiology
oncodaily.com/blog/kendric...
#AmericanSocietyOfPhotobiology #Cancer #DNAdamage #Health #OncoDaily #Oncology #Photobiology #Medicine #StanfordMedicine
oncodaily.com/blog/kendric...
#AmericanSocietyOfPhotobiology #Cancer #DNAdamage #Health #OncoDaily #Oncology #Photobiology #Medicine #StanfordMedicine
Remembering Kendric Smith, A Pioneer in Radiation Oncology and Photobiology - OncoDaily
Remembering Kendric Smith, A Pioneer in Radiation Oncology and Photobiology / American Society of Photobiology, cancer, DNA damage, Henry Kaplan, Kendric
oncodaily.com
January 9, 2025 at 5:14 PM
Remembering Kendric Smith, A Pioneer in Radiation Oncology and Photobiology
oncodaily.com/blog/kendric...
#AmericanSocietyOfPhotobiology #Cancer #DNAdamage #Health #OncoDaily #Oncology #Photobiology #Medicine #StanfordMedicine
oncodaily.com/blog/kendric...
#AmericanSocietyOfPhotobiology #Cancer #DNAdamage #Health #OncoDaily #Oncology #Photobiology #Medicine #StanfordMedicine
The HeatDDR doctoral network training school in full swing @iebcas.bsky.social @pecinka-grp.bsky.social @zeiss-microscopy.bsky.social #microscopy #DNAdamage
January 28, 2026 at 7:16 AM
The HeatDDR doctoral network training school in full swing @iebcas.bsky.social @pecinka-grp.bsky.social @zeiss-microscopy.bsky.social #microscopy #DNAdamage
Hello Bluesky!
We are a research network of 13 PhD researchers exploring DNA repair mechanisms 🧬
🏛️ Partnering with research institutions across Europe
💡 Fostering collaborations between academia and industry to drive innovation
#RepState #DNADamage #DNARepair #ScientificResearch #EUResearch
We are a research network of 13 PhD researchers exploring DNA repair mechanisms 🧬
🏛️ Partnering with research institutions across Europe
💡 Fostering collaborations between academia and industry to drive innovation
#RepState #DNADamage #DNARepair #ScientificResearch #EUResearch
February 3, 2025 at 6:25 PM
Hello Bluesky!
We are a research network of 13 PhD researchers exploring DNA repair mechanisms 🧬
🏛️ Partnering with research institutions across Europe
💡 Fostering collaborations between academia and industry to drive innovation
#RepState #DNADamage #DNARepair #ScientificResearch #EUResearch
We are a research network of 13 PhD researchers exploring DNA repair mechanisms 🧬
🏛️ Partnering with research institutions across Europe
💡 Fostering collaborations between academia and industry to drive innovation
#RepState #DNADamage #DNARepair #ScientificResearch #EUResearch
Whole-body p21 transgenic🐭
#SkeletalMuscle atrophy fibrosis
⏬Treadmill Grip strength
SkM transcriptomic #Senescence #SASP
⏬OXPHOS
⏫myonuclei & interstitial cell #DNADamage
p21 OE does Not increase p16 in SkM
Nathan LeBrasseur lab #MolMetab 2023
www.sciencedirect.com/science/arti...
#SkeletalMuscle atrophy fibrosis
⏬Treadmill Grip strength
SkM transcriptomic #Senescence #SASP
⏬OXPHOS
⏫myonuclei & interstitial cell #DNADamage
p21 OE does Not increase p16 in SkM
Nathan LeBrasseur lab #MolMetab 2023
www.sciencedirect.com/science/arti...
January 25, 2026 at 8:10 PM
Whole-body p21 transgenic🐭
#SkeletalMuscle atrophy fibrosis
⏬Treadmill Grip strength
SkM transcriptomic #Senescence #SASP
⏬OXPHOS
⏫myonuclei & interstitial cell #DNADamage
p21 OE does Not increase p16 in SkM
Nathan LeBrasseur lab #MolMetab 2023
www.sciencedirect.com/science/arti...
#SkeletalMuscle atrophy fibrosis
⏬Treadmill Grip strength
SkM transcriptomic #Senescence #SASP
⏬OXPHOS
⏫myonuclei & interstitial cell #DNADamage
p21 OE does Not increase p16 in SkM
Nathan LeBrasseur lab #MolMetab 2023
www.sciencedirect.com/science/arti...
Review officially out at Trends in Cancer: www.sciencedirect.com/science/arti... V proud of this one, it talks about some of the lab's favorite theories for non-repair roles for DDR proteins. Awesome work by Megha and Tyler in the lab to write this along with kickass figures
#DNArepair #DNAdamage
#DNArepair #DNAdamage
January 14, 2025 at 4:00 PM
Review officially out at Trends in Cancer: www.sciencedirect.com/science/arti... V proud of this one, it talks about some of the lab's favorite theories for non-repair roles for DDR proteins. Awesome work by Megha and Tyler in the lab to write this along with kickass figures
#DNArepair #DNAdamage
#DNArepair #DNAdamage
Learn about the #DNAdamage response in #CellPhysiology and diseases in the eponymous EMBO Workshop in #Sounio, #Greece, 12–16 October 2026.
Deadline: 17 May 2026
https://meetings.embo.org/event/26-dna-damage
#EMBODNADamageResponse #genesky #LifeSciences #research #meeting #EMBOevents 🧪
Deadline: 17 May 2026
https://meetings.embo.org/event/26-dna-damage
#EMBODNADamageResponse #genesky #LifeSciences #research #meeting #EMBOevents 🧪
March 24, 2026 at 3:10 PM
Learn about the #DNAdamage response in #CellPhysiology and diseases in the eponymous EMBO Workshop in #Sounio, #Greece, 12–16 October 2026.
Deadline: 17 May 2026
https://meetings.embo.org/event/26-dna-damage
#EMBODNADamageResponse #genesky #LifeSciences #research #meeting #EMBOevents 🧪
Deadline: 17 May 2026
https://meetings.embo.org/event/26-dna-damage
#EMBODNADamageResponse #genesky #LifeSciences #research #meeting #EMBOevents 🧪
DISCOVER-Seq has a lot of advantages over other methods for determining off-target activity
See the data and consider this new method for gene editing, DNA Damage / Repair analysis
🟢 bit.ly/3Nj2xn8
#Epigenetics #Genomics #DNADamage #CRISPR
See the data and consider this new method for gene editing, DNA Damage / Repair analysis
🟢 bit.ly/3Nj2xn8
#Epigenetics #Genomics #DNADamage #CRISPR
December 3, 2024 at 10:25 PM
DISCOVER-Seq has a lot of advantages over other methods for determining off-target activity
See the data and consider this new method for gene editing, DNA Damage / Repair analysis
🟢 bit.ly/3Nj2xn8
#Epigenetics #Genomics #DNADamage #CRISPR
See the data and consider this new method for gene editing, DNA Damage / Repair analysis
🟢 bit.ly/3Nj2xn8
#Epigenetics #Genomics #DNADamage #CRISPR
Männliche Patienten hatten mehr DNA-Schäden als weibliche (13,45 % vs. 8,15 %, p < 0,05).
www.mdpi.com/1422-0067/25...
#LongCovid #Coronavirus #DNADamage #COVID19 #SARSCoV2 #ImpfenSchuetzt
www.mdpi.com/1422-0067/25...
#LongCovid #Coronavirus #DNADamage #COVID19 #SARSCoV2 #ImpfenSchuetzt
DNA Damage in Moderate and Severe COVID-19 Cases: Relation to Demographic, Clinical, and Laboratory Parameters
The ability of the SARS-CoV-2 virus to cause DNA damage in infected humans requires its study as a potential indicator of COVID-19 progression. DNA damage was studied in leukocytes of 65 COVID-19 pati...
www.mdpi.com
October 18, 2024 at 10:24 PM
Männliche Patienten hatten mehr DNA-Schäden als weibliche (13,45 % vs. 8,15 %, p < 0,05).
www.mdpi.com/1422-0067/25...
#LongCovid #Coronavirus #DNADamage #COVID19 #SARSCoV2 #ImpfenSchuetzt
www.mdpi.com/1422-0067/25...
#LongCovid #Coronavirus #DNADamage #COVID19 #SARSCoV2 #ImpfenSchuetzt
Epigenetics Update - Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits go.nature.com/45HFBqf
#Epigenetics #Toxoplasmagondii #DNADamage
---
Perfect for cancer, immunology, and aging research; epigenometech.com
#Epigenetics #Toxoplasmagondii #DNADamage
---
Perfect for cancer, immunology, and aging research; epigenometech.com
August 26, 2025 at 1:05 PM
Epigenetics Update - Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits go.nature.com/45HFBqf
#Epigenetics #Toxoplasmagondii #DNADamage
---
Perfect for cancer, immunology, and aging research; epigenometech.com
#Epigenetics #Toxoplasmagondii #DNADamage
---
Perfect for cancer, immunology, and aging research; epigenometech.com
PARP1 hyperactivity stalls translation and triggers #stressgranule formation following DNA damage. New study from Maria Tereshchenko, Rebecca Earnshaw
Hyun O. Lee @utoronto.ca:
rupress.org/jcb/article/...
#Physiology #CellSignaling #Biochemistry #DNAbiology #DNAdamage
Hyun O. Lee @utoronto.ca:
rupress.org/jcb/article/...
#Physiology #CellSignaling #Biochemistry #DNAbiology #DNAdamage
August 5, 2026 at 1:45 PM
PARP1 hyperactivity stalls translation and triggers #stressgranule formation following DNA damage. New study from Maria Tereshchenko, Rebecca Earnshaw
Hyun O. Lee @utoronto.ca:
rupress.org/jcb/article/...
#Physiology #CellSignaling #Biochemistry #DNAbiology #DNAdamage
Hyun O. Lee @utoronto.ca:
rupress.org/jcb/article/...
#Physiology #CellSignaling #Biochemistry #DNAbiology #DNAdamage
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
December 9, 2025 at 4:01 PM
RESEARCH PAPER: Multiple human enhancer RNAs contain long translated open reading frames
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
By Vlasov et al. and James Manley
➡️ https://genesdev.cshlp.org/content/39/23-24/1468.full
#protein #translation #enhancerRNA #openreadingframe #chromatin #DNAdamage #RNAprocessing #nucleus
Comentario en JARG sobre los efectos y por qué vigilar el daño al ADN en reproducción asistida:
buff.ly/dWxRJLC
#bianorbiotech #ART #DNADamage #SDF #IVF
buff.ly/dWxRJLC
#bianorbiotech #ART #DNADamage #SDF #IVF
DNA damage control in IVF: precariously positioned between physiology and disease - Journal of Assisted Reproduction and Genetics
Journal of Assisted Reproduction and Genetics -
buff.ly
May 19, 2026 at 6:04 AM
Comentario en JARG sobre los efectos y por qué vigilar el daño al ADN en reproducción asistida:
buff.ly/dWxRJLC
#bianorbiotech #ART #DNADamage #SDF #IVF
buff.ly/dWxRJLC
#bianorbiotech #ART #DNADamage #SDF #IVF
🧬 Thrilled to share that our latest work, A landmark study uncovering intricate molecular details of the human DNA repair process.
📰 Press release: elifesciences.org/for-the-pres...
📄 Full article: elifesciences.org/reviewed-pre...
Proud of the team #DNADamage #CryoEM #CambridgeUniversity
📰 Press release: elifesciences.org/for-the-pres...
📄 Full article: elifesciences.org/reviewed-pre...
Proud of the team #DNADamage #CryoEM #CambridgeUniversity
May 27, 2025 at 2:08 PM
🧬 Thrilled to share that our latest work, A landmark study uncovering intricate molecular details of the human DNA repair process.
📰 Press release: elifesciences.org/for-the-pres...
📄 Full article: elifesciences.org/reviewed-pre...
Proud of the team #DNADamage #CryoEM #CambridgeUniversity
📰 Press release: elifesciences.org/for-the-pres...
📄 Full article: elifesciences.org/reviewed-pre...
Proud of the team #DNADamage #CryoEM #CambridgeUniversity
#research #DNAdamage
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4–Xpf–Ercc1 nuclease complex in the Fanconi anaemia pathway
(Havlikova, Dejmek, Huskova, Allan, Boura, Nencka & Silhan) – CommBiology: doi.org/10.1038/s420...
@iocbprague.bsky.social @czechacademy.bsky.social
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4–Xpf–Ercc1 nuclease complex in the Fanconi anaemia pathway
(Havlikova, Dejmek, Huskova, Allan, Boura, Nencka & Silhan) – CommBiology: doi.org/10.1038/s420...
@iocbprague.bsky.social @czechacademy.bsky.social
November 27, 2025 at 9:14 AM
#research #DNAdamage
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4–Xpf–Ercc1 nuclease complex in the Fanconi anaemia pathway
(Havlikova, Dejmek, Huskova, Allan, Boura, Nencka & Silhan) – CommBiology: doi.org/10.1038/s420...
@iocbprague.bsky.social @czechacademy.bsky.social
Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4–Xpf–Ercc1 nuclease complex in the Fanconi anaemia pathway
(Havlikova, Dejmek, Huskova, Allan, Boura, Nencka & Silhan) – CommBiology: doi.org/10.1038/s420...
@iocbprague.bsky.social @czechacademy.bsky.social