Their circulating levels distinguished #BreastCancer patients with lung metastases from those with localized tumors, suggesting #biomarker potential. @pku1898.bsky.social
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Their circulating levels distinguished #BreastCancer patients with lung metastases from those with localized tumors, suggesting #biomarker potential. @pku1898.bsky.social
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Zebrafish screening identified epothilone B as a potential #IBD therapy, promoting neutrophil #apoptosis to reduce inflammation and support intestinal repair.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Zebrafish screening identified epothilone B as a potential #IBD therapy, promoting neutrophil #apoptosis to reduce inflammation and support intestinal repair.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Extracellular vesicles deliver #ACSL4, triggering ferroptosis and mitochondrial damage, revealing a potential target to protect #LiverGrafts.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
Extracellular vesicles deliver #ACSL4, triggering ferroptosis and mitochondrial damage, revealing a potential target to protect #LiverGrafts.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies #m6A-modified circLPAR3 as a driver of docetaxel resistance in #ProstateCancer, highlighting a potential target for restoring treatment response.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies #m6A-modified circLPAR3 as a driver of docetaxel resistance in #ProstateCancer, highlighting a potential target for restoring treatment response.
#GenesAndDiseases: doi.org/10.1016/j.ge...
#HighSalt activates SGK-1–mTOR signaling, weakening the #SkinBarrier and promoting inflammation; combined SGK-1 and JAK inhibition eased symptoms in preclinical models.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
#HighSalt activates SGK-1–mTOR signaling, weakening the #SkinBarrier and promoting inflammation; combined SGK-1 and JAK inhibition eased symptoms in preclinical models.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals that CCN1 regulates microglial distribution and activation through region-specific CSF1 and IL2 signaling during #BrainDevelopment. #SpatialTranscriptomics
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals that CCN1 regulates microglial distribution and activation through region-specific CSF1 and IL2 signaling during #BrainDevelopment. #SpatialTranscriptomics
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how neoliensinine triggers lysosome-dependent cell death in T-cell malignancies by disrupting #CholesterolHomeostasis through the STING–TUBA1B pathway.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how neoliensinine triggers lysosome-dependent cell death in T-cell malignancies by disrupting #CholesterolHomeostasis through the STING–TUBA1B pathway.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study shows that routine #FirstTrimester markers combined with #AI improve #preeclampsia prediction, enabling earlier risk identification and management. @fudan-university.bsky.social
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study shows that routine #FirstTrimester markers combined with #AI improve #preeclampsia prediction, enabling earlier risk identification and management. @fudan-university.bsky.social
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how Dlc1 deficiency activates #WntSignaling, disrupting #CardiacProgenitor differentiation and later #cardiomyocyte generation.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how Dlc1 deficiency activates #WntSignaling, disrupting #CardiacProgenitor differentiation and later #cardiomyocyte generation.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
A 3D silk-fiber model revealed greater #tenofovir-induced mitochondrial dysfunction and oxidative stress in elderly donor-derived renal stem cells. @wakeforest.bsky.social
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
A 3D silk-fiber model revealed greater #tenofovir-induced mitochondrial dysfunction and oxidative stress in elderly donor-derived renal stem cells. @wakeforest.bsky.social
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies psiTPTE22-HERV as a #TumourSuppressor in #GastricCancer, showing that its epigenetic silencing promotes disease, while low expression predicts poorer survival.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies psiTPTE22-HERV as a #TumourSuppressor in #GastricCancer, showing that its epigenetic silencing promotes disease, while low expression predicts poorer survival.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study links a #MED14 mutation to VACTERL-like defects by impairing gene expression and multi-organ development. #RNApolymeraseII
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study links a #MED14 mutation to VACTERL-like defects by impairing gene expression and multi-organ development. #RNApolymeraseII
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies γH2AX as a key driver of #glioblastoma stemness and #tumour growth, highlighting the SET-PP2A axis as a promising target for limiting recurrence and invasion. #H2AX
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies γH2AX as a key driver of #glioblastoma stemness and #tumour growth, highlighting the SET-PP2A axis as a promising target for limiting recurrence and invasion. #H2AX
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how TAZ promotes IL-6 expression and #M2macrophage polarization, helping protect against #hypoxia-induced #LungInjury.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study reveals how TAZ promotes IL-6 expression and #M2macrophage polarization, helping protect against #hypoxia-induced #LungInjury.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how #MucosalVaccines & inhalable antibodies could strengthen local immunity, improve protection, and advance prevention against #RespiratoryInfections.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how #MucosalVaccines & inhalable antibodies could strengthen local immunity, improve protection, and advance prevention against #RespiratoryInfections.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies CCT2 as a driver of #HNSCC progression and #CisplatinResistance, revealing it as a target & showing resistant cells can transfer CCT2 to promote #chemoresistance.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies CCT2 as a driver of #HNSCC progression and #CisplatinResistance, revealing it as a target & showing resistant cells can transfer CCT2 to promote #chemoresistance.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies the lncRNA SERHL as a suppressor of #GastricCancer progression, revealing its potential as a #biomarker and therapeutic target through inhibition of KLF16 signalling.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies the lncRNA SERHL as a suppressor of #GastricCancer progression, revealing its potential as a #biomarker and therapeutic target through inhibition of KLF16 signalling.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies DLL3 as a driver of #tumor progression and T-cell exhaustion in neuroendocrine cervical carcinoma, revealing a promising therapeutic target. @fudanuni_official
#GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies DLL3 as a driver of #tumor progression and T-cell exhaustion in neuroendocrine cervical carcinoma, revealing a promising therapeutic target. @fudanuni_official
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review highlights how #miRNAs regulate apoptosis & treatment response in #BreastCancer, revealing their potential as #radiosensitisers that could help overcome therapy resistance.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review highlights how #miRNAs regulate apoptosis & treatment response in #BreastCancer, revealing their potential as #radiosensitisers that could help overcome therapy resistance.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how lipophagy reduces oxidative stress and offers new therapeutic strategies for metabolic, cardiovascular, and neurological disorders.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how lipophagy reduces oxidative stress and offers new therapeutic strategies for metabolic, cardiovascular, and neurological disorders.
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores #EGFR expression patterns, co-targeting strategies, and #nanocarrier-based delivery systems to improve treatment efficacy and enable personalized care.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores #EGFR expression patterns, co-targeting strategies, and #nanocarrier-based delivery systems to improve treatment efficacy and enable personalized care.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review links #AirPollution, lung dysbiosis, and the #LungBrainAxis to #epileptogenesis, offering new perspectives for understanding and treating epilepsy. @monashuniversity.bsky.social
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review links #AirPollution, lung dysbiosis, and the #LungBrainAxis to #epileptogenesis, offering new perspectives for understanding and treating epilepsy. @monashuniversity.bsky.social
#GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how #PiezoChannels regulate tooth movement, #dentofacial deformities, and pain, revealing potential targets for improved #orthodontic care.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how #PiezoChannels regulate tooth movement, #dentofacial deformities, and pain, revealing potential targets for improved #orthodontic care.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how diet, gut microbes, and systemic metabolism shape tumor growth and treatment response, highlighting #AI and multi-omics for personalized #oncology.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how diet, gut microbes, and systemic metabolism shape tumor growth and treatment response, highlighting #AI and multi-omics for personalized #oncology.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how disrupted #MitochondrialDynamics drives #TNBC growth and chemoresistance, revealing new therapeutic opportunities.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This review explores how disrupted #MitochondrialDynamics drives #TNBC growth and chemoresistance, revealing new therapeutic opportunities.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...