Preeclampsia is a pregnancy-specific hypertensive disorder characterized by new-onset hypertension after 20 weeks of gestation, accompanied by end-organ dysfunction with or without proteinuria. Af...

In humans, the membrane-bound serine protease prostasin encoded by Prss8 is associated with preeclampsia, a gestational hypertension disorder affecting blood supply of the placenta. Deficiency of Prss...

Preeclampsia, eclampsia and HELLP syndrome are disorders that occur only during pregnancy and the postpartum period, which affect both the mother and the unborn baby. Preeclampsia affects at least 5 percent of all pregnancies, it is a rapidly progressive condition characterized by high blood pressure, swelling and protein in the urine. Sudden weight gain, headaches and changes in vision are important symptoms; however, some women with rapidly advancing disease report few symptoms

Researchers at the University of Manchester and Manchester University NHS Foundation Trust have uncovered a hidden defect in the tiny blood vessels of women with preeclampsia, a dangerous and common pregnancy complication that can threaten the lives of both mother and baby.

North Shields mother told to make appointment to give birth to dead baby

Delighted to share a new lab story by Dr. Sara Di Carlo providing new insights on prostasin-associated preeclampsia risk and defective embryonic hematopoiesis upon CAP1 loss. It has been a pleasure to...

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Placental malaria (PM), driven by sequestration of Plasmodium falciparum-infected erythrocytes within the placental intervillous space, remains a major contributor to adverse maternal and fetal outcomes in endemic regions. Increasing evidence suggests that PM may also contribute to the development of preeclampsia (PE), a leading cause of maternal and perinatal morbidity and mortality worldwide. Although PM and PE arise from distinct initiating events, Plasmodium falciparum sequestration in PM...

Late-onset preeclampsia (LOPE) is a major pregnancy complication characterized by hypertension and placental dysfunction, resolving only upon deliv...