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Now available through Canadian Liver Journal #AdvanceAccess: a new study examines the impact of direct-acting antiviral treatment on time and out-of-pocket costs for hepatitis C patients. Read the findings: bit.ly/CanLivJAA-12 #LiverResearch
October 30, 2026 at 12:30 PM
tumorscholar.bsky.social
Furan fatty acids reprogram hepatic lipid metabolism via acyl-CoA conjugates in obesity.

#LiverResearch #LiverSky #Hepatology
https://doi.org/10.1126/sciadv.aeg5357
Furan fatty acids reprogram hepatic lipid metabolism via acyl-CoA conjugates in obesity.
Dietary fish oil (FO) and omega-3 fatty acids are associated with cardiometabolic benefits, yet their molecular mediators remain incompletely defined. Furan fatty acids (FuFAs), a distinct lipid class enriched in FO, have emerged as potential regulators of metabolic health. Here, we identify and qua
doi.org
October 29, 2026 at 2:28 PM
liversmdpi.bsky.social
📢 New Issue in #LiversMDPI

📚 Livers, Volume 6, Issue 5 is now online with 27 articles.

⭐ Cover Story: Modeling #Hepatic Ischemia–Reperfusion Injury: From 2D and Animal Models to Advanced 3D Platforms

🔗 Explore the full issue: www.mdpi.com/2673-4389/6/5

#LiverResearch #LiverTransplantation
October 29, 2026 at 9:06 AM
tumorscholar.bsky.social
IL-19 limits macrophage-driven inflammation in acetaminophen-induced liver injury

#LiverResearch #LiverSky #Hepatology
https://doi.org/https://www.sciencedirect.com/science/article/pii/S0168827826027431?dgcid=rss_sd_all
IL-19 limits macrophage-driven inflammation in acetaminophen-induced liver injury
Publication date: November 2026 Source: Journal of Hepatology, Volume 85, Issue 5 Author(s): Dongwei Jia, Yasuko Iwakiri
doi.org
October 26, 2026 at 10:20 AM
tumorscholar.bsky.social
Targeted lactate depletion via gluconeogenesis by engineered hepatocyte-based micronanorobots for radiosensitization and immune activation

#LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.xcrm.2026.103123
Targeted lactate depletion via gluconeogenesis by engineered hepatocyte-based micronanorobots for radiosensitization and immune activation
Fan et al. develop CXCR4-engineered hepatocyte cytoplasts integrated with Au-Pt nanorobots to deplete tumor lactate through gluconeogenesis. Lactate depletion suppresses repair-associated lactylation and impairs MRN-mediated DNA repair, while Au-Pt catalysis amplifies radiation-induced damage. This
doi.org
October 26, 2026 at 10:20 AM
aasldnews.bsky.social
From education and new insights to conversations with colleagues and connections across the hepatology community, here’s just a glimpse of what could be on your agenda at #TLM26.

What will your days at TLM look like? 👀

#Hepatology #LiverResearch
October 20, 2026 at 4:06 PM
tumorscholar.bsky.social
Glutamine metabolism keeps pathogenic hepatic CD4 + T cells in check.

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.09.004
Glutamine metabolism keeps pathogenic hepatic CD4 + T cells in check.
Sawada et al. show that glutamine metabolism through glutaminolysis restrains O-GlcNAcylation and pathogenic inflammatory cytokine production by hepatic CD4 + T cells during MASLD. Glutamine supplementation restores hepatic glutamine availability and limits liver injury, and these findings reveal a
doi.org
October 19, 2026 at 2:40 PM
asipath.bsky.social
There is still time to register for this #SLAMCommunity #VirtualEvent! Register here https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology @harvardmed.bsky.social
October 13, 2026 at 1:04 PM
tumorscholar.bsky.social
Inhibiting fructose metabolism to treat fatty liver

#LiverResearch #LiverSky #Hepatology
https://doi.org/10.1038/s42255-026-01627-4
Inhibiting fructose metabolism to treat fatty liver
doi.org
October 13, 2026 at 12:17 PM
asipath.bsky.social
Join us in fabulous Las Vegas for #Pathobiology2027 next spring!
Deadlines on December 28:
♠️Early registration
♦️Abstract submission
♣️Award applications

Learn more at asip.org/pathobiology2027
#PathobiologyResearch #Immunology #LiverResearch #RegenerativeBiology #DiseaseResearch #Metabolism
October 12, 2026 at 1:04 PM
asipath.bsky.social
This month, the #SLAMCommunity is hosting its first #VirtualEvent! Register today https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology @harvardmed.bsky.social
October 2, 2026 at 1:04 PM
asipath.bsky.social
Viva Las Vegas! Join us in fabulous Las Vegas for #Pathobiology2027 next spring asip.org/pathobiology2027

#PathobiologyResearch #Immunology #LiverResearch #RegenerativeBiology #DiseaseResearch #Metabolism #ASIP
October 1, 2026 at 1:04 PM
drhowardsmith.bsky.social
MIT DEVELOPS INJECTABLE “MINI LIVERS” THAT WORK INSIDE THE BODY. These injectable “mini livers” could someday boost the function of a failing liver without the need for a liver transplant. #MiniLivers #LiverResearch #RegenerativeMedicine #TransplantResearch #MedicalResearch
September 30, 2026 at 7:31 PM
ki.se
Researchers have developed a molecule that boosts cells’ ability to repair oxidative #DNADamage. In human liver cells and mice, it reduced liver injury caused by paracetamol toxicity and improved survival. Published in Advanced Science. #LiverResearch 🧪

news.ki.se/new-molecule...
September 28, 2026 at 12:30 PM
tumorscholar.bsky.social
Single-nucleus transcriptomics refine the hepatic cellular context of the MASLD proteosurvival signature.

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1136/gutjnl-2026-340378
Single-nucleus transcriptomics refine the hepatic cellular context of the MASLD proteosurvival signature.
doi.org
September 28, 2026 at 11:08 AM
tumorscholar.bsky.social
Restoration of aged liver regeneration by youthful systemic factors via LTβ-driven hepatocyte reprogramming

#LiverResearch #LiverSky #Hepatology
https://doi.org/https://www.sciencedirect.com/science/article/pii/S016882782602893X?dgcid=rss_sd_all
Restoration of aged liver regeneration by youthful systemic factors via LTβ-driven hepatocyte reprogramming
Publication date: Available online 23 September 2026 Source: Journal of Hepatology Author(s): Jiang Chenhao, Han Lu, Liu Yasong, Zhang Jianhao, Chen Huaxin, Wen Xinyun, Chi Xianda, Fan Linda, Li Tianyi, Shi Shaojun, Chen Sunrui, Xiao Jiaqi, Lv Xing, Zhang Jiebin, Zhao Xuegang, Zhang Yujun, Liu Jianr
doi.org
September 25, 2026 at 9:56 AM
asipath.bsky.social
You don't want to miss the first virtual event for the Summer Liver Academy Meeting (SLAM) Community. Join us on October 15 for a fantastic talk from Dr. Zhenghui Jiang https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology @harvardmed.bsky.social
September 24, 2026 at 1:04 PM
tumorscholar.bsky.social
Restoring liver glutamine suppresses inflammation and limits liver injury. These findings identify T cell glutamine metabolism as a key metabolic checkpoint and promising therapeutic target in MASLD.

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.08.018
Glutamine metabolism as a rheostat of CD4+ T cell pathogenic function in metabolic dysfunction-associated steatotic liver disease
Sawada et al. show that reduced hepatic glutamine drives pathogenic CD4+ T cell responses that promote MASLD progression. Restoring liver glutamine suppresses inflammation and limits liver injury. These findings identify T cell glutamine metabolism as a key metabolic checkpoint and promising therape
doi.org
September 19, 2026 at 10:31 AM
asipath.bsky.social
Calling all liver lovers! We are excited to announce the first virtual event for the Summer Liver Academy Meeting (SLAM) Community. Join us on October 15 for a fantastic talk from Dr. Zhenghui Jiang https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology
September 18, 2026 at 3:40 PM
tumorscholar.bsky.social
Zonated cholesterol sensing by SIRT2 drives MASLD-HCC

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.08.015
Zonated cholesterol sensing by SIRT2 drives MASLD-HCC
Zhang et al. identify SIRT2 as a zonated cholesterol sensor in periportal hepatocytes, where chronic cholesterol overload hyperactivates SIRT2 to suppress CYP7B1‑mediated bile acid synthesis, leading to 27‑hydroxycholesterol accumulation and ultimately driving MASLD‑HCC.
doi.org
September 18, 2026 at 8:17 AM
liversmdpi.bsky.social
📢 New Issue in #LiversMDPI

📚 Volume 6, Issue 4 is now online with 27 articles

⭐ Cover Story: Hepatic crown-like structures, cell heterogeneity, and their role in steatotic liver diseases

🔗 Full issue here: mdpi.com/2673-4389/6/4

#Hepatology #LiverResearch #SteatoticLiver
September 16, 2026 at 7:55 AM
tumorscholar.bsky.social
While vascular control of organ function mechanisms have been discovered in essentially all major organs, the mechanisms of translating milieu factors into angiocrine signalling mechanisms remain largely elusive.

#LiverResearch #LiverSky #Hepatology
https://doi.org/10.1038/s41467-026-76966-7
Haemodynamic control of zonated liver function via instructive vascular Wnt signalling.
The vascular endothelium forms a systemically disseminated organ that translates micromilieu factors into instructive cues, designated as angiocrine signalling. While vascular control of organ function mechanisms have been discovered in essentially all major organs, the mechanisms of translating mil
doi.org
September 11, 2026 at 8:07 AM
uoftpress.bsky.social
New research in the Canadian Liver Journal (Volume 9, Issue 3) investigates the prognostic value of myosteatosis on post-transplant survival and cardiometabolic outcomes. Explore the findings: bit.ly/CanLivJ9-3c University Health Network Research at UHN #LiverResearch
September 9, 2026 at 2:25 PM
tumorscholar.bsky.social
Restoring β-hydroxybutyrate reverses T cell exhaustion and improves antitumor, antiviral, and CAR T cell immunity in aged hosts, revealing a metabolic strategy to rejuvenate immune function during aging.

#LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.08.009
Aging microenvironment induces CD8+ T cell exhaustion by suppressing hepatic β-hydroxybutyrylate synthesis
Xiao et al. identify a liver-derived β-hydroxybutyrate-CREM signaling axis that drives CD8+ T cell immunosenescence. Restoring β-hydroxybutyrate reverses T cell exhaustion and improves antitumor, antiviral, and CAR T cell immunity in aged hosts, revealing a metabolic strategy to rejuvenate immune fu
doi.org
September 8, 2026 at 9:37 AM
pscsupport.bsky.social
Why was less benefit seen when people took Urso (UDCA) on the Norucholic Acid (NCA) trial? This extract is from a special Ask the Expert session with international PSC experts. Full session & extracts here: buff.ly/GvnxfNl #LetsBeatPSC #PSCSupport #LiverTreatment #LiverResearch
September 4, 2026 at 7:58 AM