Tumour-Immune Cell Dynamics Lab
@witherslab.bsky.social
We are the Withers lab, based at the @oxcio.bsky.social at the Nuffield Department of Medicine, Oxford.
Our research is focused upon understanding how immune cells adapt to, and are changed by tissues, particularly the tumour microenvironment.
Our research is focused upon understanding how immune cells adapt to, and are changed by tissues, particularly the tumour microenvironment.
Yesterday our first year iCASE DPhil Student Sam, has presented his project and first achievements during CIOs weekly seminar.
Together with @astra-zeneca.bsky.social he will explore potential improvements in immune checkpoint inhibitor therapy!
Together with @astra-zeneca.bsky.social he will explore potential improvements in immune checkpoint inhibitor therapy!
May 22, 2026 at 7:33 AM
Yesterday our first year iCASE DPhil Student Sam, has presented his project and first achievements during CIOs weekly seminar.
Together with @astra-zeneca.bsky.social he will explore potential improvements in immune checkpoint inhibitor therapy!
Together with @astra-zeneca.bsky.social he will explore potential improvements in immune checkpoint inhibitor therapy!
Reposted by Tumour-Immune Cell Dynamics Lab
This Friday, we are carrying out the first CIO Fun Run™️, a non-competitive 5-10K for everyone in our department, with a social drinks and snacks get-together afterwards.
We are raising money for #CancerResearchUK @cruk-mi.bsky.social
🏃♂️🏃🏾♀️🏃🏼♀️🏃🏻🏃🏽♂️
Donate here:
fundraise.cancerresearchuk.org/page/cio-run...
We are raising money for #CancerResearchUK @cruk-mi.bsky.social
🏃♂️🏃🏾♀️🏃🏼♀️🏃🏻🏃🏽♂️
Donate here:
fundraise.cancerresearchuk.org/page/cio-run...
CIO Run Fun 2026 CRUK Fundraiser
Thanks for taking the time to visit my fundraising page.
Cancer is happening right now, which is why I’m fundraising right now for Cancer Research UK. There’s no time to lose!
Donate to my page today...
fundraise.cancerresearchuk.org
May 20, 2026 at 7:40 PM
This Friday, we are carrying out the first CIO Fun Run™️, a non-competitive 5-10K for everyone in our department, with a social drinks and snacks get-together afterwards.
We are raising money for #CancerResearchUK @cruk-mi.bsky.social
🏃♂️🏃🏾♀️🏃🏼♀️🏃🏻🏃🏽♂️
Donate here:
fundraise.cancerresearchuk.org/page/cio-run...
We are raising money for #CancerResearchUK @cruk-mi.bsky.social
🏃♂️🏃🏾♀️🏃🏼♀️🏃🏻🏃🏽♂️
Donate here:
fundraise.cancerresearchuk.org/page/cio-run...
Last week, our second year DPhil Student @ch4rlet.bsky.social presented her recent work about an #orthotopic model of colorectal cancer our weekly @oxcio.bsky.social seminar 👏🔬
#cancerimmunology #witherslab
#cancerimmunology #witherslab
April 27, 2026 at 11:59 AM
Last week, our second year DPhil Student @ch4rlet.bsky.social presented her recent work about an #orthotopic model of colorectal cancer our weekly @oxcio.bsky.social seminar 👏🔬
#cancerimmunology #witherslab
#cancerimmunology #witherslab
This week we attended the @oxfordcancer.bsky.social and the @britsocimm.bsky.social -Oxford symposium 👩🏼💻🗒️👨💻
We are proud to share that at BSI-Oxford, our PostDoc @nabinapun.bsky.social won the prize for the best talk & our RA Paul won the best poster!
💪🏆🎉👏
Withers lab represent!
We are proud to share that at BSI-Oxford, our PostDoc @nabinapun.bsky.social won the prize for the best talk & our RA Paul won the best poster!
💪🏆🎉👏
Withers lab represent!
April 2, 2026 at 4:59 AM
This week we attended the @oxfordcancer.bsky.social and the @britsocimm.bsky.social -Oxford symposium 👩🏼💻🗒️👨💻
We are proud to share that at BSI-Oxford, our PostDoc @nabinapun.bsky.social won the prize for the best talk & our RA Paul won the best poster!
💪🏆🎉👏
Withers lab represent!
We are proud to share that at BSI-Oxford, our PostDoc @nabinapun.bsky.social won the prize for the best talk & our RA Paul won the best poster!
💪🏆🎉👏
Withers lab represent!
Reposted by Tumour-Immune Cell Dynamics Lab
…(ii) Adoptively transferred Tmem33-/- (KO) OT-I CD8+ T cells massively expand in B16F10-OVA and show greater Tpex accumulation in tumours and draining lymph nodes compared to Tmem33+/+ (WT) OT-I (thank you @witherslab.bsky.social )…. 6/10
January 5, 2026 at 3:30 PM
…(ii) Adoptively transferred Tmem33-/- (KO) OT-I CD8+ T cells massively expand in B16F10-OVA and show greater Tpex accumulation in tumours and draining lymph nodes compared to Tmem33+/+ (WT) OT-I (thank you @witherslab.bsky.social )…. 6/10
Reposted by Tumour-Immune Cell Dynamics Lab
Parkes lab pre-print alert! ‘TMEM33 deletion potentiates anti-tumor CD8⁺ T cell immunity.’ Led by mtjackson101.bsky.social. Full bluetutorial follows! 1/10 www.biorxiv.org/content/10.6...
January 5, 2026 at 3:30 PM
Parkes lab pre-print alert! ‘TMEM33 deletion potentiates anti-tumor CD8⁺ T cell immunity.’ Led by mtjackson101.bsky.social. Full bluetutorial follows! 1/10 www.biorxiv.org/content/10.6...
We’re happy to be in Liverpool for this years @britsocimm.bsky.social congress:
In today’s “What’s hot in cancer immunology?” session, Prof David Withers presented our new data on an orthotopic colorectal cancer model for the first time! 🐭💪
In today’s “What’s hot in cancer immunology?” session, Prof David Withers presented our new data on an orthotopic colorectal cancer model for the first time! 🐭💪
December 3, 2025 at 5:02 PM
We’re happy to be in Liverpool for this years @britsocimm.bsky.social congress:
In today’s “What’s hot in cancer immunology?” session, Prof David Withers presented our new data on an orthotopic colorectal cancer model for the first time! 🐭💪
In today’s “What’s hot in cancer immunology?” session, Prof David Withers presented our new data on an orthotopic colorectal cancer model for the first time! 🐭💪
Today, our PostDoc @lisav17.bsky.social has presented her progress on alternative experimental approaches to our current Kaede system in the @oxcio.bsky.social weekly seminar!
🧬🔦
🧬🔦
November 13, 2025 at 2:01 PM
Today, our PostDoc @lisav17.bsky.social has presented her progress on alternative experimental approaches to our current Kaede system in the @oxcio.bsky.social weekly seminar!
🧬🔦
🧬🔦
Reposted by Tumour-Immune Cell Dynamics Lab
I am grateful for the experience I gained, the people I met & the amazing support in my lab group!
I end this day full of excitement for what’s next to come 🔬🧫
I end this day full of excitement for what’s next to come 🔬🧫
November 10, 2025 at 10:37 PM
I am grateful for the experience I gained, the people I met & the amazing support in my lab group!
I end this day full of excitement for what’s next to come 🔬🧫
I end this day full of excitement for what’s next to come 🔬🧫
Reposted by Tumour-Immune Cell Dynamics Lab
Today I successfully passed my Transfer of Status from ‘DPhil Candidate’ to ‘DPhil Student’. It was amazing to present my past years work in detail & get feedback!
It’s a steep learning curve but today was rewarding! 📈
It’s a steep learning curve but today was rewarding! 📈
November 10, 2025 at 10:37 PM
Today I successfully passed my Transfer of Status from ‘DPhil Candidate’ to ‘DPhil Student’. It was amazing to present my past years work in detail & get feedback!
It’s a steep learning curve but today was rewarding! 📈
It’s a steep learning curve but today was rewarding! 📈
In this weeks @oxcio.bsky.social seminar, our PostDoc Pascale presented her current progress on setting up #SingleCellSequencing experiments and their analysis for the @witherslab.bsky.social in Oxford! 🖥️💡🐭
Exciting!!!
Exciting!!!
October 23, 2025 at 12:50 PM
In this weeks @oxcio.bsky.social seminar, our PostDoc Pascale presented her current progress on setting up #SingleCellSequencing experiments and their analysis for the @witherslab.bsky.social in Oxford! 🖥️💡🐭
Exciting!!!
Exciting!!!
Today we kicked off the @oxcio.bsky.social weekly seminar presenting our most recent achievements🔬
Our PostDoc @nabinapun.bsky.social gave insight into her research on myeloid cells in the TME our RA @ioannisguida.bsky.social presented a conclusion of his work in the #WithersLab before he leaves us!
Our PostDoc @nabinapun.bsky.social gave insight into her research on myeloid cells in the TME our RA @ioannisguida.bsky.social presented a conclusion of his work in the #WithersLab before he leaves us!
September 11, 2025 at 5:47 PM
Today we kicked off the @oxcio.bsky.social weekly seminar presenting our most recent achievements🔬
Our PostDoc @nabinapun.bsky.social gave insight into her research on myeloid cells in the TME our RA @ioannisguida.bsky.social presented a conclusion of his work in the #WithersLab before he leaves us!
Our PostDoc @nabinapun.bsky.social gave insight into her research on myeloid cells in the TME our RA @ioannisguida.bsky.social presented a conclusion of his work in the #WithersLab before he leaves us!
Reposted by Tumour-Immune Cell Dynamics Lab
Yesterday we finished with prize-giving and drinks in the garden🥂🌱! 🏆 Posters for Bas, Cindy & Charlotte📃; postdoc talk for Qian 👩🏫 & best embossing artwork for Group8 🧑🎨 Shoutout to Lisha for the Rhodes House tours, acknowledging its history, the good and the uncomfortable ⚖️. What a day! #CIOawayday
July 10, 2025 at 7:15 AM
Yesterday we finished with prize-giving and drinks in the garden🥂🌱! 🏆 Posters for Bas, Cindy & Charlotte📃; postdoc talk for Qian 👩🏫 & best embossing artwork for Group8 🧑🎨 Shoutout to Lisha for the Rhodes House tours, acknowledging its history, the good and the uncomfortable ⚖️. What a day! #CIOawayday
Reposted by Tumour-Immune Cell Dynamics Lab
✨ Kicking off #CIOawayday with our senior PIs sharing the experiments that changed their careers 🧑🔬👩🔬🧫 A reminder that serendipity, curiosity, and pub chats can spark groundbreaking ideas 🤓 Clearly science thrives on kindness and collaboration and we got a lot of that in #CIO 😉🙃 #ScienceLife
July 9, 2025 at 11:37 AM
✨ Kicking off #CIOawayday with our senior PIs sharing the experiments that changed their careers 🧑🔬👩🔬🧫 A reminder that serendipity, curiosity, and pub chats can spark groundbreaking ideas 🤓 Clearly science thrives on kindness and collaboration and we got a lot of that in #CIO 😉🙃 #ScienceLife
Reposted by Tumour-Immune Cell Dynamics Lab
We’re at the #OCION Symposium today @oxfordcancer.bsky.social
💡🧬A full day of inspiring talks, cutting-edge science, and collaborative energy as we explore the vibrant cancer research landscape across Oxford. From immuno-oncology to early detection & precision medicine #OxfordCancer #CancerResearch
💡🧬A full day of inspiring talks, cutting-edge science, and collaborative energy as we explore the vibrant cancer research landscape across Oxford. From immuno-oncology to early detection & precision medicine #OxfordCancer #CancerResearch
June 13, 2025 at 9:11 AM
We’re at the #OCION Symposium today @oxfordcancer.bsky.social
💡🧬A full day of inspiring talks, cutting-edge science, and collaborative energy as we explore the vibrant cancer research landscape across Oxford. From immuno-oncology to early detection & precision medicine #OxfordCancer #CancerResearch
💡🧬A full day of inspiring talks, cutting-edge science, and collaborative energy as we explore the vibrant cancer research landscape across Oxford. From immuno-oncology to early detection & precision medicine #OxfordCancer #CancerResearch
Today we’re at the @britsocimm.bsky.social Bristol Immunolgy Group presenting some of our recent data!
June 11, 2025 at 11:01 AM
Today we’re at the @britsocimm.bsky.social Bristol Immunolgy Group presenting some of our recent data!
Reposted by Tumour-Immune Cell Dynamics Lab
There are only a few tickets left for this year's Oxford Liver Cancer Centre of Excellence Symposium!
Ensure to secure your place before registration closes on the 5th of May! ⬇️ @medsci.ox.ac.uk #LiverCancer
www.eventbrite.co.uk/e/oxford-liv...
Ensure to secure your place before registration closes on the 5th of May! ⬇️ @medsci.ox.ac.uk #LiverCancer
www.eventbrite.co.uk/e/oxford-liv...
Oxford Liver Cancer Centre of Excellence 2025 Symposium
An event focused on advancing scientific collaboration and improving outcomes for liver cancer.
www.eventbrite.co.uk
April 30, 2025 at 7:25 AM
There are only a few tickets left for this year's Oxford Liver Cancer Centre of Excellence Symposium!
Ensure to secure your place before registration closes on the 5th of May! ⬇️ @medsci.ox.ac.uk #LiverCancer
www.eventbrite.co.uk/e/oxford-liv...
Ensure to secure your place before registration closes on the 5th of May! ⬇️ @medsci.ox.ac.uk #LiverCancer
www.eventbrite.co.uk/e/oxford-liv...
Reposted by Tumour-Immune Cell Dynamics Lab
🤓 Great talks today at the Spacial Biology seminar from OCION and @medsci.ox.ac.uk
Inspiring inisghts from Simon Leedham and our very own David Withers! @witherslab.bsky.social
#SpacialBiology #ImmuneDynamics #OxfordResearch #OCION
Inspiring inisghts from Simon Leedham and our very own David Withers! @witherslab.bsky.social
#SpacialBiology #ImmuneDynamics #OxfordResearch #OCION
April 29, 2025 at 4:32 PM
🤓 Great talks today at the Spacial Biology seminar from OCION and @medsci.ox.ac.uk
Inspiring inisghts from Simon Leedham and our very own David Withers! @witherslab.bsky.social
#SpacialBiology #ImmuneDynamics #OxfordResearch #OCION
Inspiring inisghts from Simon Leedham and our very own David Withers! @witherslab.bsky.social
#SpacialBiology #ImmuneDynamics #OxfordResearch #OCION
Reposted by Tumour-Immune Cell Dynamics Lab
Fantastic talk from our #CIO PI, David Withers @witherslab.bsky.social, this morning at @imm.ox.ac.uk on tumour immune cell dynamics—great insights from an elegant mouse model to track entry and resident immune cells within tumours🐭🧫🧪 #TumourImmunology #NK #Tregs
March 14, 2025 at 10:42 AM
Fantastic talk from our #CIO PI, David Withers @witherslab.bsky.social, this morning at @imm.ox.ac.uk on tumour immune cell dynamics—great insights from an elegant mouse model to track entry and resident immune cells within tumours🐭🧫🧪 #TumourImmunology #NK #Tregs
Reposted by Tumour-Immune Cell Dynamics Lab
🚨Today at our #CIOseminars Prof David Withers @witherslab.bsky.social will share his group’s latest research:
👉Investigating Intratumoural Treg Recruitment and Retention
📍NDMRB Seminar room ⏰ 13h
Join us! 🧬🔥 #Immunology #CancerResearch #Tregs #CIOseminars
www.immonc.ox.ac.uk/team/david-w...
👉Investigating Intratumoural Treg Recruitment and Retention
📍NDMRB Seminar room ⏰ 13h
Join us! 🧬🔥 #Immunology #CancerResearch #Tregs #CIOseminars
www.immonc.ox.ac.uk/team/david-w...
David Withers
PhD David Withers - Group Leader in Experimental Cancer Immunology
www.immonc.ox.ac.uk
February 6, 2025 at 11:08 AM
🚨Today at our #CIOseminars Prof David Withers @witherslab.bsky.social will share his group’s latest research:
👉Investigating Intratumoural Treg Recruitment and Retention
📍NDMRB Seminar room ⏰ 13h
Join us! 🧬🔥 #Immunology #CancerResearch #Tregs #CIOseminars
www.immonc.ox.ac.uk/team/david-w...
👉Investigating Intratumoural Treg Recruitment and Retention
📍NDMRB Seminar room ⏰ 13h
Join us! 🧬🔥 #Immunology #CancerResearch #Tregs #CIOseminars
www.immonc.ox.ac.uk/team/david-w...