Xun Wang
@xunwang.bsky.social
Reposted by Xun Wang
New paper from Dr. Wen Gu on the impact of L-2-hydroxyglutarate deficiency on neural stem cell function and neuronal differentiation. Interesting connection between an IEM and chronic oncogene activation. Thanks to Dr. Bushra Afroze and her patients for participating.
www.jci.org/articles/vie...
www.jci.org/articles/vie...
JCI -
L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
www.jci.org
March 19, 2026 at 5:41 PM
New paper from Dr. Wen Gu on the impact of L-2-hydroxyglutarate deficiency on neural stem cell function and neuronal differentiation. Interesting connection between an IEM and chronic oncogene activation. Thanks to Dr. Bushra Afroze and her patients for participating.
www.jci.org/articles/vie...
www.jci.org/articles/vie...