Panel Discussion # 2 focused on ARTNet's collaborative approach to translating resistance biology into therapheutic strategies.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 12, 2025 at 3:59 PM
Panel Discussion # 2 focused on ARTNet's collaborative approach to translating resistance biology into therapheutic strategies.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
Cell States, Metabolism and Inflammatory Microenvironment WG shared updates on spatial multi-omics projects tackling therapy resistance in lung, pancreatic & breast cancers, and a joint white paper with PSRC.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 12, 2025 at 2:58 PM
Cell States, Metabolism and Inflammatory Microenvironment WG shared updates on spatial multi-omics projects tackling therapy resistance in lung, pancreatic & breast cancers, and a joint white paper with PSRC.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
Dr. Seth Gammon presented updates from the Functional Screens&Assay Development WG. Highlights included a new white paper on targeting acquired resistance, a pilot grant on novel screening & collaborative efforts to uncover shared drug vulnerabilities.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 12, 2025 at 2:56 PM
Dr. Seth Gammon presented updates from the Functional Screens&Assay Development WG. Highlights included a new white paper on targeting acquired resistance, a pilot grant on novel screening & collaborative efforts to uncover shared drug vulnerabilities.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
Dr. Alan Hutson shared updates from the ARTNet CDMC U24
@roswellpark.bsky.social, featuring new resource-sharing catalogs, collaborative research initiatives, and AI-driven tools to enhance cancer research and foster cross-network collaboration.
#ARTNetScientificRetreat2025
@roswellpark.bsky.social, featuring new resource-sharing catalogs, collaborative research initiatives, and AI-driven tools to enhance cancer research and foster cross-network collaboration.
#ARTNetScientificRetreat2025
September 12, 2025 at 2:51 PM
Dr. Alan Hutson shared updates from the ARTNet CDMC U24
@roswellpark.bsky.social, featuring new resource-sharing catalogs, collaborative research initiatives, and AI-driven tools to enhance cancer research and foster cross-network collaboration.
#ARTNetScientificRetreat2025
@roswellpark.bsky.social, featuring new resource-sharing catalogs, collaborative research initiatives, and AI-driven tools to enhance cancer research and foster cross-network collaboration.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025 Poster Session
September 11, 2025 at 9:43 PM
#ARTNetScientificRetreat2025 Poster Session
Flash Talks for Poster Presenters featured research with translational potential:
Katherine Dempsey from PCAC U54 explored SAT1 & CAF polarization in pancreatic cancer.
#ARTNetScientificRetreat2025
Katherine Dempsey from PCAC U54 explored SAT1 & CAF polarization in pancreatic cancer.
#ARTNetScientificRetreat2025
September 11, 2025 at 9:42 PM
Flash Talks for Poster Presenters featured research with translational potential:
Katherine Dempsey from PCAC U54 explored SAT1 & CAF polarization in pancreatic cancer.
#ARTNetScientificRetreat2025
Katherine Dempsey from PCAC U54 explored SAT1 & CAF polarization in pancreatic cancer.
#ARTNetScientificRetreat2025
#ESITalk: Dr.Vincent Bernard (ARTI U54)
@mdanderson.bsky.social revealed how spatial profiling uncovers persister cell populations and immune reshaping after radiation in pancreatic cancer. Targeting KRAS and ferroptosis/cuproptosis defenses may improve radiosensitivity
#ARTNetScientificRetreat2025
@mdanderson.bsky.social revealed how spatial profiling uncovers persister cell populations and immune reshaping after radiation in pancreatic cancer. Targeting KRAS and ferroptosis/cuproptosis defenses may improve radiosensitivity
#ARTNetScientificRetreat2025
September 11, 2025 at 8:47 PM
#ESITalk: Dr.Vincent Bernard (ARTI U54)
@mdanderson.bsky.social revealed how spatial profiling uncovers persister cell populations and immune reshaping after radiation in pancreatic cancer. Targeting KRAS and ferroptosis/cuproptosis defenses may improve radiosensitivity
#ARTNetScientificRetreat2025
@mdanderson.bsky.social revealed how spatial profiling uncovers persister cell populations and immune reshaping after radiation in pancreatic cancer. Targeting KRAS and ferroptosis/cuproptosis defenses may improve radiosensitivity
#ARTNetScientificRetreat2025
#ECITalks: Melissa Stewart from AML U54 @ohsuknight.bsky.social shared how combining venetoclax with the CDK4/6 inhibitor palbociclib overcomes resistance in RAS-mutant AML, reducing tumor burden, improving survival, and reshaping protein synthesis pathways.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 11, 2025 at 8:31 PM
#ECITalks: Melissa Stewart from AML U54 @ohsuknight.bsky.social shared how combining venetoclax with the CDK4/6 inhibitor palbociclib overcomes resistance in RAS-mutant AML, reducing tumor burden, improving survival, and reshaping protein synthesis pathways.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
#ECITalk: Dr. Moran Amit from H-CARR U54 at @mdanderson.bsky.social shared how tumor-associated nerves drive cancer progression, #metastasis, and therapy resistance. Targeting the neural-tumor microenvironment opens new paths for cancer treatment and #immunotherapy.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 11, 2025 at 8:12 PM
#ECITalk: Dr. Moran Amit from H-CARR U54 at @mdanderson.bsky.social shared how tumor-associated nerves drive cancer progression, #metastasis, and therapy resistance. Targeting the neural-tumor microenvironment opens new paths for cancer treatment and #immunotherapy.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
#ECITalk: Dr. Surendra Shukla from ARTNet PCAC U54 shared how BACH1 drives pancreatic cancer progression and FOLFIRINOX resistance. Targeting BACH1, directly or with hemin, enhances therapy efficacy and reveals PDIA6 as a key player in unfolded protein response.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 11, 2025 at 7:53 PM
#ECITalk: Dr. Surendra Shukla from ARTNet PCAC U54 shared how BACH1 drives pancreatic cancer progression and FOLFIRINOX resistance. Targeting BACH1, directly or with hemin, enhances therapy efficacy and reveals PDIA6 as a key player in unfolded protein response.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
Dr. Trever Bivona from BAATAAR-UP center shared findings of how tumor lineages adapt to targeted therapy in EGFR-mutant #lungcancer. Combination strategies such as osimertinib+sonidegib can overcome resistance driven by transcriptional plasticity
tinyurl.com/43d6sma4
#ARTNetScientificRetreat2025
tinyurl.com/43d6sma4
#ARTNetScientificRetreat2025
September 11, 2025 at 7:23 PM
Dr. Trever Bivona from BAATAAR-UP center shared findings of how tumor lineages adapt to targeted therapy in EGFR-mutant #lungcancer. Combination strategies such as osimertinib+sonidegib can overcome resistance driven by transcriptional plasticity
tinyurl.com/43d6sma4
#ARTNetScientificRetreat2025
tinyurl.com/43d6sma4
#ARTNetScientificRetreat2025
Dr. Jeffrey Tyner (ARTNet AML center) highlighted how AML cell differentiation states govern therapy response & resistance. His team developed Myelo-ID, a rapid gene expression test that predicts outcomes & helps guide treatment decisions.
Read more: tinyurl.com/kpt3483z
#ARTNetScientificRetreat2025
Read more: tinyurl.com/kpt3483z
#ARTNetScientificRetreat2025
September 11, 2025 at 6:47 PM
Dr. Jeffrey Tyner (ARTNet AML center) highlighted how AML cell differentiation states govern therapy response & resistance. His team developed Myelo-ID, a rapid gene expression test that predicts outcomes & helps guide treatment decisions.
Read more: tinyurl.com/kpt3483z
#ARTNetScientificRetreat2025
Read more: tinyurl.com/kpt3483z
#ARTNetScientificRetreat2025
Dr. Jeffrey Myers shared advances in overcoming cisplatin resistance in head & neck cancer, highlighting NRF2-driven resistance, immune suppression, and novel biomarkers like HP-MRI and exosomal miRNAs for precision therapy.
More info: nciartnet.org/en/members/h...
#ARTNetScientificRetreat2025
More info: nciartnet.org/en/members/h...
#ARTNetScientificRetreat2025
September 11, 2025 at 5:06 PM
Dr. Jeffrey Myers shared advances in overcoming cisplatin resistance in head & neck cancer, highlighting NRF2-driven resistance, immune suppression, and novel biomarkers like HP-MRI and exosomal miRNAs for precision therapy.
More info: nciartnet.org/en/members/h...
#ARTNetScientificRetreat2025
More info: nciartnet.org/en/members/h...
#ARTNetScientificRetreat2025
Dr. Pankaj Singh shared updates from the Pancreatic Cancer ARTNet Center (PCAC), highlighting metabolic drivers of resistance, MUC1-mediated exosome signaling, and targeting Cyclin K to overcome therapy resistance
More on ARTNet PCAC center:
nciartnet.org/en/members/p...
#ARTNetScientificRetreat2025
More on ARTNet PCAC center:
nciartnet.org/en/members/p...
#ARTNetScientificRetreat2025
September 11, 2025 at 4:40 PM
Dr. Pankaj Singh shared updates from the Pancreatic Cancer ARTNet Center (PCAC), highlighting metabolic drivers of resistance, MUC1-mediated exosome signaling, and targeting Cyclin K to overcome therapy resistance
More on ARTNet PCAC center:
nciartnet.org/en/members/p...
#ARTNetScientificRetreat2025
More on ARTNet PCAC center:
nciartnet.org/en/members/p...
#ARTNetScientificRetreat2025
Panelist Dr. Pankaj Singh highlighted cancer disparities among American Indian and Alaska Native populations, emphasizing systemic inequities, limited tissue access, and lack of models.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
September 11, 2025 at 4:01 PM
Panelist Dr. Pankaj Singh highlighted cancer disparities among American Indian and Alaska Native populations, emphasizing systemic inequities, limited tissue access, and lack of models.
#ARTNetScientificRetreat2025
#ARTNetScientificRetreat2025
Panelist Dr. Chinthalapally V. Rao of OUHealthScience
highlighted stark disparities in colorectal cancer among African American & American Indian/Alaska Native populations in Oklahoma, linking molecular differences, inflammation, and access to care to survival outcomes. #ARTNetScientificRetreat2025
highlighted stark disparities in colorectal cancer among African American & American Indian/Alaska Native populations in Oklahoma, linking molecular differences, inflammation, and access to care to survival outcomes. #ARTNetScientificRetreat2025
September 11, 2025 at 3:59 PM
Panelist Dr. Chinthalapally V. Rao of OUHealthScience
highlighted stark disparities in colorectal cancer among African American & American Indian/Alaska Native populations in Oklahoma, linking molecular differences, inflammation, and access to care to survival outcomes. #ARTNetScientificRetreat2025
highlighted stark disparities in colorectal cancer among African American & American Indian/Alaska Native populations in Oklahoma, linking molecular differences, inflammation, and access to care to survival outcomes. #ARTNetScientificRetreat2025
Panelist Dr. Victoria Seewaldt of City of Hope presented research on treatment-resistant triple-negative breast cancer, revealing early aggressive tumor microenvironment biology and highlighting complement C3 as a potential target for therapy. #ARTNetScientificRetreat2025
September 11, 2025 at 3:57 PM
Panelist Dr. Victoria Seewaldt of City of Hope presented research on treatment-resistant triple-negative breast cancer, revealing early aggressive tumor microenvironment biology and highlighting complement C3 as a potential target for therapy. #ARTNetScientificRetreat2025
Panelist Dr. Jose Trevino of VCUHealth highlighted efforts to address cancer health disparities through the U4HELPP program and Rapid Autopsy Program, advancing understanding of pancreatic cancer and metastatic disease. #ARTNetScientificRetreat2025 #CancerResearch
September 11, 2025 at 3:56 PM
Panelist Dr. Jose Trevino of VCUHealth highlighted efforts to address cancer health disparities through the U4HELPP program and Rapid Autopsy Program, advancing understanding of pancreatic cancer and metastatic disease. #ARTNetScientificRetreat2025 #CancerResearch
Panel Discussion: Clinical Patterns and Biological Mechanisms of Outcome Disparities and Acquired Resistance.
Moderator: Dr. Jeffrey Tyner
Panelists: Dr. Jose Trevino, Dr. Victoria Seewaldt, Dr. Chinthalapally V. Rao, and Dr. Pankaj Singh
#ARTNetScientificRetreat2025
Moderator: Dr. Jeffrey Tyner
Panelists: Dr. Jose Trevino, Dr. Victoria Seewaldt, Dr. Chinthalapally V. Rao, and Dr. Pankaj Singh
#ARTNetScientificRetreat2025
September 11, 2025 at 3:54 PM
Panel Discussion: Clinical Patterns and Biological Mechanisms of Outcome Disparities and Acquired Resistance.
Moderator: Dr. Jeffrey Tyner
Panelists: Dr. Jose Trevino, Dr. Victoria Seewaldt, Dr. Chinthalapally V. Rao, and Dr. Pankaj Singh
#ARTNetScientificRetreat2025
Moderator: Dr. Jeffrey Tyner
Panelists: Dr. Jose Trevino, Dr. Victoria Seewaldt, Dr. Chinthalapally V. Rao, and Dr. Pankaj Singh
#ARTNetScientificRetreat2025
At #ARTNetScientificRetreat2025, keynote speaker Dr. Veronica Galvan Hart, shared insights on how aging and cellular senescence connect Alzheimer’s disease and cancer, highlighting tau-induced senescence and opportunities for early intervention.
Learn more about her research: galvanlab.org
Learn more about her research: galvanlab.org
September 11, 2025 at 2:34 PM
At #ARTNetScientificRetreat2025, keynote speaker Dr. Veronica Galvan Hart, shared insights on how aging and cellular senescence connect Alzheimer’s disease and cancer, highlighting tau-induced senescence and opportunities for early intervention.
Learn more about her research: galvanlab.org
Learn more about her research: galvanlab.org
Dr. Robert Mannel, Director of Stephenson Cancer Center,
introduced the OU Health Stephenson Cancer Center (SCC)
#ARTNetScientificRetreat2025
introduced the OU Health Stephenson Cancer Center (SCC)
#ARTNetScientificRetreat2025
September 11, 2025 at 2:31 PM
Dr. Robert Mannel, Director of Stephenson Cancer Center,
introduced the OU Health Stephenson Cancer Center (SCC)
#ARTNetScientificRetreat2025
introduced the OU Health Stephenson Cancer Center (SCC)
#ARTNetScientificRetreat2025
Dr. Ian Dunn, Executive Dean of the College of Medicine
Chief Academic Officer, introduced the University of Oklahoma Health Sceince Center.
#ARTNetScientificRetreat2025
Chief Academic Officer, introduced the University of Oklahoma Health Sceince Center.
#ARTNetScientificRetreat2025
September 11, 2025 at 2:29 PM
Dr. Ian Dunn, Executive Dean of the College of Medicine
Chief Academic Officer, introduced the University of Oklahoma Health Sceince Center.
#ARTNetScientificRetreat2025
Chief Academic Officer, introduced the University of Oklahoma Health Sceince Center.
#ARTNetScientificRetreat2025
Two days of the #ARTNetScientificRetreat2025 are taking place at the University of Oklahoma Health Science Center.
hosted by our OUHSC U54 Center PI, Dr. Pankaj Singh.
hosted by our OUHSC U54 Center PI, Dr. Pankaj Singh.
September 11, 2025 at 2:26 PM
Two days of the #ARTNetScientificRetreat2025 are taking place at the University of Oklahoma Health Science Center.
hosted by our OUHSC U54 Center PI, Dr. Pankaj Singh.
hosted by our OUHSC U54 Center PI, Dr. Pankaj Singh.