At ASGCT 2026, INSERM presented CRISPR-based work in DMD - aiming to switch on utrophin through epigenetic regulation, sparking discussion on mutation-independent strategies and gene regulation tools for muscular dystrophies.
#ASGCT26 #GeneTherapy #MAGIC
At ASGCT 2026, INSERM presented CRISPR-based work in DMD - aiming to switch on utrophin through epigenetic regulation, sparking discussion on mutation-independent strategies and gene regulation tools for muscular dystrophies.
#ASGCT26 #GeneTherapy #MAGIC
endpoints.news/asgct26-a-zi...
endpoints.news/asgct26-a-zi...
🔹Engineering CasX for therapeutic-grade in vivo editing with DeepXE, a predictive model for guide potency
🔹ADDing a lock to epigenome editing: DNMT3A allostery enhances specificity and potency of CRISPR-CasX-based epigenetic repressors
🔹Engineering CasX for therapeutic-grade in vivo editing with DeepXE, a predictive model for guide potency
🔹ADDing a lock to epigenome editing: DNMT3A allostery enhances specificity and potency of CRISPR-CasX-based epigenetic repressors
#ASGCT #ASGCT26 #CRISPR #geneediting
#ASGCT #ASGCT26 #CRISPR #geneediting
www.nytimes.com/2026/05/11/h...
www.nytimes.com/2026/05/11/h...
Published on Sunday, April 5, 2026
Published on Sunday, April 5, 2026