Interesting talk by @olallalab.bsky.social at #AdvancesChemBio. She talked about her group's work on various peptide-based #ChemBio tools. Interesting insights e.g. into peptide-based binders to Elongin BC, which induce apoptosis in cancer cells. #chemsky www.cell.com/cell-chemica...
January 22, 2025 at 10:48 AM
Interesting talk by @olallalab.bsky.social at #AdvancesChemBio. She talked about her group's work on various peptide-based #ChemBio tools. Interesting insights e.g. into peptide-based binders to Elongin BC, which induce apoptosis in cancer cells. #chemsky www.cell.com/cell-chemica...
Great talk by @jessenlab.bsky.social at the #AdvancesChemBio. He talked about his group's work on magic spot nucleotides. Interesting insights into the analytical detection, (chemoenzymatic) synthesis and involvement in plant-pathogen interactions. #chemsky #ChemBio pubs.acs.org/doi/full/10....
January 21, 2025 at 1:32 PM
Great talk by @jessenlab.bsky.social at the #AdvancesChemBio. He talked about his group's work on magic spot nucleotides. Interesting insights into the analytical detection, (chemoenzymatic) synthesis and involvement in plant-pathogen interactions. #chemsky #ChemBio pubs.acs.org/doi/full/10....
I had an amazing time at the #AdvancesChemBio with many interesting talks, exciting posters and inspiring discussions with colleagues and friends.
Thank you so much to the organizers from @gfg-chembio.bsky.social for organizing such an outstanding meeting. #chemsky #ChemBio
Thank you so much to the organizers from @gfg-chembio.bsky.social for organizing such an outstanding meeting. #chemsky #ChemBio
January 22, 2025 at 5:32 PM
I had an amazing time at the #AdvancesChemBio with many interesting talks, exciting posters and inspiring discussions with colleagues and friends.
Thank you so much to the organizers from @gfg-chembio.bsky.social for organizing such an outstanding meeting. #chemsky #ChemBio
Thank you so much to the organizers from @gfg-chembio.bsky.social for organizing such an outstanding meeting. #chemsky #ChemBio
Why are prodrugs so prevalent in drug discovery?
The #AdvancesChemBio by @gfg-chembio.bsky.social are off to a great start with an insightful workshop by Kurt Ritter addressing this topic.
#chemsky #ChemBio #DrugDiscovery #DrugDevelopment (1/4)
dechema.de/en/Events/20...
The #AdvancesChemBio by @gfg-chembio.bsky.social are off to a great start with an insightful workshop by Kurt Ritter addressing this topic.
#chemsky #ChemBio #DrugDiscovery #DrugDevelopment (1/4)
dechema.de/en/Events/20...
January 21, 2025 at 10:19 AM
Why are prodrugs so prevalent in drug discovery?
The #AdvancesChemBio by @gfg-chembio.bsky.social are off to a great start with an insightful workshop by Kurt Ritter addressing this topic.
#chemsky #ChemBio #DrugDiscovery #DrugDevelopment (1/4)
dechema.de/en/Events/20...
The #AdvancesChemBio by @gfg-chembio.bsky.social are off to a great start with an insightful workshop by Kurt Ritter addressing this topic.
#chemsky #ChemBio #DrugDiscovery #DrugDevelopment (1/4)
dechema.de/en/Events/20...
Congratulations to our colleagues from the @gfg-chembio.bsky.social on organizing an excellent Advances in Chemical Biology #AdvancesChemBio Conference in Frankfurt. The quality of the meeting was very high and the talks and posters of outstanding quality. Thank you for the excellent organization!
January 22, 2025 at 5:41 PM
Congratulations to our colleagues from the @gfg-chembio.bsky.social on organizing an excellent Advances in Chemical Biology #AdvancesChemBio Conference in Frankfurt. The quality of the meeting was very high and the talks and posters of outstanding quality. Thank you for the excellent organization!
Trypanosomal infections are an important challenge to human health.
@hellmichgroup.bsky.social talked at #AdvancesChemBio about a covalent inhibitor for tryparedoxin and about a detailed study of its mechanism including chemically induced protein dimerization onlinelibrary.wiley.com/doi/full/10....
@hellmichgroup.bsky.social talked at #AdvancesChemBio about a covalent inhibitor for tryparedoxin and about a detailed study of its mechanism including chemically induced protein dimerization onlinelibrary.wiley.com/doi/full/10....
January 22, 2025 at 1:32 PM
Trypanosomal infections are an important challenge to human health.
@hellmichgroup.bsky.social talked at #AdvancesChemBio about a covalent inhibitor for tryparedoxin and about a detailed study of its mechanism including chemically induced protein dimerization onlinelibrary.wiley.com/doi/full/10....
@hellmichgroup.bsky.social talked at #AdvancesChemBio about a covalent inhibitor for tryparedoxin and about a detailed study of its mechanism including chemically induced protein dimerization onlinelibrary.wiley.com/doi/full/10....
Great talk by Andrea Hupfeld at #AdvancesChemBio. She talked about incorporating photoswitchable amino acids into enzymes to photocontrol their activity. Exciting application to bacterial asparaginase, for which substrate selectivity is switched. #ChemBio #chemsky www.degruyter.com/document/doi...
January 21, 2025 at 3:46 PM
Great talk by Andrea Hupfeld at #AdvancesChemBio. She talked about incorporating photoswitchable amino acids into enzymes to photocontrol their activity. Exciting application to bacterial asparaginase, for which substrate selectivity is switched. #ChemBio #chemsky www.degruyter.com/document/doi...
While kinases are among the most important drug targets, their counterparts, the protein phosphates, are much less explored.
A great lecture by @mkoehn.bsky.social at #AdvancesChemBio gave insights into better understanding and potentially targeting this enzyme class. pubs.rsc.org/en/content/a...
A great lecture by @mkoehn.bsky.social at #AdvancesChemBio gave insights into better understanding and potentially targeting this enzyme class. pubs.rsc.org/en/content/a...
January 22, 2025 at 5:28 PM
While kinases are among the most important drug targets, their counterparts, the protein phosphates, are much less explored.
A great lecture by @mkoehn.bsky.social at #AdvancesChemBio gave insights into better understanding and potentially targeting this enzyme class. pubs.rsc.org/en/content/a...
A great lecture by @mkoehn.bsky.social at #AdvancesChemBio gave insights into better understanding and potentially targeting this enzyme class. pubs.rsc.org/en/content/a...
Understanding posttranslational modifications (PTMs) is often key to mechanistically understanding human health and disease.
At #AdvancesChemBio Pavel Kielkowski talked about his group's impressive work on chemical proteomics to study complex PTMs such as AMPylation. www.biorxiv.org/content/10.1...
At #AdvancesChemBio Pavel Kielkowski talked about his group's impressive work on chemical proteomics to study complex PTMs such as AMPylation. www.biorxiv.org/content/10.1...
January 22, 2025 at 9:14 AM
Understanding posttranslational modifications (PTMs) is often key to mechanistically understanding human health and disease.
At #AdvancesChemBio Pavel Kielkowski talked about his group's impressive work on chemical proteomics to study complex PTMs such as AMPylation. www.biorxiv.org/content/10.1...
At #AdvancesChemBio Pavel Kielkowski talked about his group's impressive work on chemical proteomics to study complex PTMs such as AMPylation. www.biorxiv.org/content/10.1...
How can we efficiently identify starting points for antibiotics with novel modes-of-action?
Anna Hirsch talked about this topic at #AdvancesChemBio. She presented her group's work on fragment screening, virtual screening and dynamic combinatorial chemistry. onlinelibrary.wiley.com/doi/10.1002/...
Anna Hirsch talked about this topic at #AdvancesChemBio. She presented her group's work on fragment screening, virtual screening and dynamic combinatorial chemistry. onlinelibrary.wiley.com/doi/10.1002/...
January 22, 2025 at 8:04 AM
How can we efficiently identify starting points for antibiotics with novel modes-of-action?
Anna Hirsch talked about this topic at #AdvancesChemBio. She presented her group's work on fragment screening, virtual screening and dynamic combinatorial chemistry. onlinelibrary.wiley.com/doi/10.1002/...
Anna Hirsch talked about this topic at #AdvancesChemBio. She presented her group's work on fragment screening, virtual screening and dynamic combinatorial chemistry. onlinelibrary.wiley.com/doi/10.1002/...
Amazing talk by @globischlab.bsky.social at #AdvancesChemBio. He talked about studying the changes of metabolites produced by the microbiome in different diseases. Exciting chemical biology tools to enrich metabolites with various functional groups. (1/2) onlinelibrary.wiley.com/doi/10.1002/...
January 22, 2025 at 8:39 AM
Amazing talk by @globischlab.bsky.social at #AdvancesChemBio. He talked about studying the changes of metabolites produced by the microbiome in different diseases. Exciting chemical biology tools to enrich metabolites with various functional groups. (1/2) onlinelibrary.wiley.com/doi/10.1002/...
The human gut microbiome plays a huge role in human health and disease.
@mlakemeyer.bsky.social talked at #AdvancesChemBio about his exciting research into using an integrated #ChemBio approach to better understand protease activity in bacteria of the microbiome. www.biorxiv.org/content/10.1...
@mlakemeyer.bsky.social talked at #AdvancesChemBio about his exciting research into using an integrated #ChemBio approach to better understand protease activity in bacteria of the microbiome. www.biorxiv.org/content/10.1...
January 22, 2025 at 1:40 PM
The human gut microbiome plays a huge role in human health and disease.
@mlakemeyer.bsky.social talked at #AdvancesChemBio about his exciting research into using an integrated #ChemBio approach to better understand protease activity in bacteria of the microbiome. www.biorxiv.org/content/10.1...
@mlakemeyer.bsky.social talked at #AdvancesChemBio about his exciting research into using an integrated #ChemBio approach to better understand protease activity in bacteria of the microbiome. www.biorxiv.org/content/10.1...
Thank you @stephanhacker2.bsky.social for highlighting me talk at the fantastic #advancesChemBio conference. Great interactions with an exciting schedule in Frankfurt. #ChemBio #microbiome #metabolomics
Amazing talk by @globischlab.bsky.social at #AdvancesChemBio. He talked about studying the changes of metabolites produced by the microbiome in different diseases. Exciting chemical biology tools to enrich metabolites with various functional groups. (1/2) onlinelibrary.wiley.com/doi/10.1002/...
January 22, 2025 at 12:37 PM
Thank you @stephanhacker2.bsky.social for highlighting me talk at the fantastic #advancesChemBio conference. Great interactions with an exciting schedule in Frankfurt. #ChemBio #microbiome #metabolomics
#EFMCISCB25 by @euromedchem.bsky.social and #AdvancesChemBio by @gfg-chembio.bsky.social were amazing conferences. I learned a lot about new science and connected with many inspiring scientists. Nevertheless, after 2 weeks of traveling, I am now happy to be home and not travel much in the next time.
February 1, 2025 at 12:57 PM
#EFMCISCB25 by @euromedchem.bsky.social and #AdvancesChemBio by @gfg-chembio.bsky.social were amazing conferences. I learned a lot about new science and connected with many inspiring scientists. Nevertheless, after 2 weeks of traveling, I am now happy to be home and not travel much in the next time.
Impressive Award Lecture for the "Richard Willstätter Prize for Chemical Biology" by Peter Seeberger at #AdvancesChemBio. He talked about the importance of chemically synthesizing defined versions of biomolecules on the example of the automated synthesis of glycans. pubs.acs.org/doi/10.1021/...
January 21, 2025 at 5:16 PM
Impressive Award Lecture for the "Richard Willstätter Prize for Chemical Biology" by Peter Seeberger at #AdvancesChemBio. He talked about the importance of chemically synthesizing defined versions of biomolecules on the example of the automated synthesis of glycans. pubs.acs.org/doi/10.1021/...
Interesting talk by Kristina Bayer at #AdvancesChemBio. She talked about her work on studying the regulation of cellular protrusions incl. lamellipodia. Cool lipid-based Chemical Biology tools to obtain new insights by selectively localizing proteins to the plasma membrane. #chemsky #ChemBio
January 21, 2025 at 4:02 PM
Interesting talk by Kristina Bayer at #AdvancesChemBio. She talked about her work on studying the regulation of cellular protrusions incl. lamellipodia. Cool lipid-based Chemical Biology tools to obtain new insights by selectively localizing proteins to the plasma membrane. #chemsky #ChemBio
Very much looking forward to the Advances in Chemical Biology #AdvancesChemBio organized by the Joint Division of Chemical Biology @gfg-chembio.bsky.social that starts today in Frankfurt. Looking forward to two days of exciting science and meeting many colleagues and friends. dechema.de/en/ChemBi...
January 21, 2025 at 7:30 AM
Very much looking forward to the Advances in Chemical Biology #AdvancesChemBio organized by the Joint Division of Chemical Biology @gfg-chembio.bsky.social that starts today in Frankfurt. Looking forward to two days of exciting science and meeting many colleagues and friends. dechema.de/en/ChemBi...
The poster flash talks were a highlight of the day at #AdvancesChemBio. We learned a lot about photoswitchable amino acids, biocatalysis, protein evolution, natural product identification, luminescent DNA synthesis and protease ABPP. Very much looking forward to the poster session. #chemsky #ChemBio
January 21, 2025 at 2:20 PM
The poster flash talks were a highlight of the day at #AdvancesChemBio. We learned a lot about photoswitchable amino acids, biocatalysis, protein evolution, natural product identification, luminescent DNA synthesis and protease ABPP. Very much looking forward to the poster session. #chemsky #ChemBio
Interesting talk by Clemens Richert at the #AdvancesChemBio. He talked about his group's research on modified nucleoside monophosphates including ProTide-like prodrugs that do not require the HINT enzymes for activation. #chemsky #ChemBio onlinelibrary.wiley.com/doi/pdf/10.1...
January 21, 2025 at 1:13 PM
Interesting talk by Clemens Richert at the #AdvancesChemBio. He talked about his group's research on modified nucleoside monophosphates including ProTide-like prodrugs that do not require the HINT enzymes for activation. #chemsky #ChemBio onlinelibrary.wiley.com/doi/pdf/10.1...
Great talk by Slava Ziegler at #AdvancesChemBio. She talked about the identification of IDO1 binders based on pseudo-natural products. Interesting insights, that the hit iDeg-1 leads to supercharged degradation of IDO1 through its native E3 KLHDC3. #ChemBio #chemsky www.biorxiv.org/content/10.1...
January 22, 2025 at 2:04 PM
Great talk by Slava Ziegler at #AdvancesChemBio. She talked about the identification of IDO1 binders based on pseudo-natural products. Interesting insights, that the hit iDeg-1 leads to supercharged degradation of IDO1 through its native E3 KLHDC3. #ChemBio #chemsky www.biorxiv.org/content/10.1...
Interesting talk by Sabine Müller at #AdvancesChemBio. She talked about her group's work on the design and development of ribozymes including those that can fulfill different functions (e.g. RNA ligation and RNA cleavage) dependent on the supplied substrate. onlinelibrary.wiley.com/doi/full/10....
January 21, 2025 at 1:47 PM
Interesting talk by Sabine Müller at #AdvancesChemBio. She talked about her group's work on the design and development of ribozymes including those that can fulfill different functions (e.g. RNA ligation and RNA cleavage) dependent on the supplied substrate. onlinelibrary.wiley.com/doi/full/10....
Insightful talk by Pierre Stallforth at the #AdvancesChemBio. He talked about the identification of new natural products from complex, competing microbial communities and from biosynthetic gene clusters of ancient microbiomes of dental plaques. #chemsky #ChemBio www.science.org/doi/10.1126/...
January 21, 2025 at 12:43 PM
Insightful talk by Pierre Stallforth at the #AdvancesChemBio. He talked about the identification of new natural products from complex, competing microbial communities and from biosynthetic gene clusters of ancient microbiomes of dental plaques. #chemsky #ChemBio www.science.org/doi/10.1126/...
Great talk by Felix Hausch at #AdvancesChemBio. He talked about his group's exciting work on using site-specific photocrosslinking based on non-canonical amino acid incorporation in order to better understand structures of protein complexes in human cells. www.nature.com/articles/s41...
January 21, 2025 at 4:18 PM
Great talk by Felix Hausch at #AdvancesChemBio. He talked about his group's exciting work on using site-specific photocrosslinking based on non-canonical amino acid incorporation in order to better understand structures of protein complexes in human cells. www.nature.com/articles/s41...
Interesting talk by Zbigniew Pianowski at #AdvancesChemBio. He talked about his group's work in cyclic dipeptides and their applications as photoswitches. Exciting applications in zebrafish embryos. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
January 22, 2025 at 11:31 AM
Interesting talk by Zbigniew Pianowski at #AdvancesChemBio. He talked about his group's work in cyclic dipeptides and their applications as photoswitches. Exciting applications in zebrafish embryos. chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Interesting talk by Xinlai Cheng at #AdvancesChemBio. He talked about his group's work on developing a CRISPR/dCas9 system with an FCPF tag that allows labeling it with small molecule binders for selective epigenetic engineering at specific genes. academic.oup.com/nar/article/...
January 22, 2025 at 9:00 AM
Interesting talk by Xinlai Cheng at #AdvancesChemBio. He talked about his group's work on developing a CRISPR/dCas9 system with an FCPF tag that allows labeling it with small molecule binders for selective epigenetic engineering at specific genes. academic.oup.com/nar/article/...