November 3, 2026 at 9:36 AM
Our November issue is live!
www.nature.com/nchembio/vol...
The cover image depicts the common midwife toad. Comparative peptidomics is used to reveal disease dynamics and variation in host AMP defenses to understand how toad populations can survive disease outbreak.
www.nature.com/nchembio/vol...
The cover image depicts the common midwife toad. Comparative peptidomics is used to reveal disease dynamics and variation in host AMP defenses to understand how toad populations can survive disease outbreak.
October 27, 2026 at 5:35 PM
Do you want to present your work to the global #ABPP community?
Register for the 15th Activity-based Protein Profiling Meeting in Leiden next year and submit an abstract for an oral presentation or a poster!
www.universiteitleiden.nl/abpp2027/reg...
#ABPP2027 #ChemSky #ChemBio #ChemicalProteomics
Register for the 15th Activity-based Protein Profiling Meeting in Leiden next year and submit an abstract for an oral presentation or a poster!
www.universiteitleiden.nl/abpp2027/reg...
#ABPP2027 #ChemSky #ChemBio #ChemicalProteomics
October 29, 2026 at 1:58 PM
Do you want to present your work to the global #ABPP community?
Register for the 15th Activity-based Protein Profiling Meeting in Leiden next year and submit an abstract for an oral presentation or a poster!
www.universiteitleiden.nl/abpp2027/reg...
#ABPP2027 #ChemSky #ChemBio #ChemicalProteomics
Register for the 15th Activity-based Protein Profiling Meeting in Leiden next year and submit an abstract for an oral presentation or a poster!
www.universiteitleiden.nl/abpp2027/reg...
#ABPP2027 #ChemSky #ChemBio #ChemicalProteomics
A great time to look back at the groundbreaking papers by Eranthie Weerapana (www.nature.com/articles/nat...) and @keribackus.bsky.social (www.nature.com/articles/nat...). (2/2)
#ChemSky #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Science
#ChemSky #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Science
Proteome-wide covalent ligand discovery in native biological systems - Nature
Small molecules are powerful tools for investigating protein function, and can serve as leads for new therapeutics, but most human proteins lack known small-molecule ligands; here, a quantitative anal...
www.nature.com
October 29, 2026 at 2:18 PM
A great time to look back at the groundbreaking papers by Eranthie Weerapana (www.nature.com/articles/nat...) and @keribackus.bsky.social (www.nature.com/articles/nat...). (2/2)
#ChemSky #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Science
#ChemSky #ChemBio #ChemicalProteomics #ChemPro #ProteoProbes #DrugDiscovery #Science
We are very happy that Marc Robillard (Tagworks Pharmaceuticals) visited us today for an inspiring LED3 Lecture in front of a full lecture hall. He talked about "Click-cleavable antibody-drug conjugates and immunoconjugates".
#DrugDiscovery #Click #ClickToRelease #ADC #ChemBio #ChemSky
#DrugDiscovery #Click #ClickToRelease #ADC #ChemBio #ChemSky
October 28, 2026 at 3:27 PM
We are very happy that Marc Robillard (Tagworks Pharmaceuticals) visited us today for an inspiring LED3 Lecture in front of a full lecture hall. He talked about "Click-cleavable antibody-drug conjugates and immunoconjugates".
#DrugDiscovery #Click #ClickToRelease #ADC #ChemBio #ChemSky
#DrugDiscovery #Click #ClickToRelease #ADC #ChemBio #ChemSky
Thoughts, questions, or ideas for collaboration? Let us know in the comments!
(8/8)
#DirectToBiology #D2B #ChemRxiv #Antibiotics #DrugDiscovery #ChemSky #Chemistry #ChemicalBiology #ChemBio #AMR #MedicinalChemistry #Proteomics #Science
Leiden University - Faculty of Science
(8/8)
#DirectToBiology #D2B #ChemRxiv #Antibiotics #DrugDiscovery #ChemSky #Chemistry #ChemicalBiology #ChemBio #AMR #MedicinalChemistry #Proteomics #Science
Leiden University - Faculty of Science
October 23, 2026 at 11:13 AM
Thoughts, questions, or ideas for collaboration? Let us know in the comments!
(8/8)
#DirectToBiology #D2B #ChemRxiv #Antibiotics #DrugDiscovery #ChemSky #Chemistry #ChemicalBiology #ChemBio #AMR #MedicinalChemistry #Proteomics #Science
Leiden University - Faculty of Science
(8/8)
#DirectToBiology #D2B #ChemRxiv #Antibiotics #DrugDiscovery #ChemSky #Chemistry #ChemicalBiology #ChemBio #AMR #MedicinalChemistry #Proteomics #Science
Leiden University - Faculty of Science
October 21, 2026 at 3:37 PM
Insightful talk by Ku-Lung Hsu at the 4th Drug Discovery and Development Summit.
He talked about SuTEx chemistry for the development of covalent binders addressing lysines and tyrosines.
www.nature.com/articles/s41...
#CovalentInibitor #DrugDiscovery #ChemSky #ChemBio #Science
He talked about SuTEx chemistry for the development of covalent binders addressing lysines and tyrosines.
www.nature.com/articles/s41...
#CovalentInibitor #DrugDiscovery #ChemSky #ChemBio #Science
October 21, 2026 at 3:43 PM
Insightful talk by Ku-Lung Hsu at the 4th Drug Discovery and Development Summit.
He talked about SuTEx chemistry for the development of covalent binders addressing lysines and tyrosines.
www.nature.com/articles/s41...
#CovalentInibitor #DrugDiscovery #ChemSky #ChemBio #Science
He talked about SuTEx chemistry for the development of covalent binders addressing lysines and tyrosines.
www.nature.com/articles/s41...
#CovalentInibitor #DrugDiscovery #ChemSky #ChemBio #Science
I took a short breather during my current amazing US trip yesterday.
I had a great time at the @umichfootball.bsky.social game in Ann Arbor.
Now very much looking forward to continuing the scientific tour and visiting @nesvilab.bsky.social and @fcyucn.bsky.social tomorrow.
#ChemBio #ChemSky #Science
I had a great time at the @umichfootball.bsky.social game in Ann Arbor.
Now very much looking forward to continuing the scientific tour and visiting @nesvilab.bsky.social and @fcyucn.bsky.social tomorrow.
#ChemBio #ChemSky #Science
October 18, 2026 at 1:03 PM
I took a short breather during my current amazing US trip yesterday.
I had a great time at the @umichfootball.bsky.social game in Ann Arbor.
Now very much looking forward to continuing the scientific tour and visiting @nesvilab.bsky.social and @fcyucn.bsky.social tomorrow.
#ChemBio #ChemSky #Science
I had a great time at the @umichfootball.bsky.social game in Ann Arbor.
Now very much looking forward to continuing the scientific tour and visiting @nesvilab.bsky.social and @fcyucn.bsky.social tomorrow.
#ChemBio #ChemSky #Science
I had a great time visiting UCSF last week.
Thank you very much to Balyn Zaro for inviting me and to everyone, who attended my talk, met with me for a great discussion or joined us for dinner.
Thank you so much for having me!
(1/2)
#ChemBio #Chemistry #Science
Thank you very much to Balyn Zaro for inviting me and to everyone, who attended my talk, met with me for a great discussion or joined us for dinner.
Thank you so much for having me!
(1/2)
#ChemBio #Chemistry #Science
October 19, 2026 at 12:41 AM
I had a great time visiting UCSF last week.
Thank you very much to Balyn Zaro for inviting me and to everyone, who attended my talk, met with me for a great discussion or joined us for dinner.
Thank you so much for having me!
(1/2)
#ChemBio #Chemistry #Science
Thank you very much to Balyn Zaro for inviting me and to everyone, who attended my talk, met with me for a great discussion or joined us for dinner.
Thank you so much for having me!
(1/2)
#ChemBio #Chemistry #Science
I really enjoyed presenting our science and discussing their many insightful questions afterwards.
Thank you again for the invite, for making this possible and for showing me around the campus. (3/3)
#ChemBio #Chemistry #Science
Thank you again for the invite, for making this possible and for showing me around the campus. (3/3)
#ChemBio #Chemistry #Science
October 19, 2026 at 12:53 AM
I really enjoyed presenting our science and discussing their many insightful questions afterwards.
Thank you again for the invite, for making this possible and for showing me around the campus. (3/3)
#ChemBio #Chemistry #Science
Thank you again for the invite, for making this possible and for showing me around the campus. (3/3)
#ChemBio #Chemistry #Science
How can chemical reaction products efficiently be isolated using crystalography?
In this great resource, Jacob DeForest gives an insightful practical guide on crystallization for Medicinal Chemists.
pubs.acs.org/jmcmar/...
#ChemSky #MedChem #ChemBio #Solids #Crystals #Crystallization #Science
In this great resource, Jacob DeForest gives an insightful practical guide on crystallization for Medicinal Chemists.
pubs.acs.org/jmcmar/...
#ChemSky #MedChem #ChemBio #Solids #Crystals #Crystallization #Science
October 17, 2026 at 1:34 PM
How can chemical reaction products efficiently be isolated using crystalography?
In this great resource, Jacob DeForest gives an insightful practical guide on crystallization for Medicinal Chemists.
pubs.acs.org/jmcmar/...
#ChemSky #MedChem #ChemBio #Solids #Crystals #Crystallization #Science
In this great resource, Jacob DeForest gives an insightful practical guide on crystallization for Medicinal Chemists.
pubs.acs.org/jmcmar/...
#ChemSky #MedChem #ChemBio #Solids #Crystals #Crystallization #Science
➡️ Actu IPCM : ipcm.fr/soutenance-d...
✨Journée importante pour Tom LACOMA (équipe CHEMBIO) qui soutient sa thèse:
« Synthèse de complexes d’or anticancéreux à ligands hémilabiles : relation structure-réactivité, spéciation et mode d’action »
📅 Mardi 23 octobre 2026, ⏰14:00
✨Journée importante pour Tom LACOMA (équipe CHEMBIO) qui soutient sa thèse:
« Synthèse de complexes d’or anticancéreux à ligands hémilabiles : relation structure-réactivité, spéciation et mode d’action »
📅 Mardi 23 octobre 2026, ⏰14:00
October 16, 2026 at 8:11 AM
➡️ Actu IPCM : ipcm.fr/soutenance-d...
✨Journée importante pour Tom LACOMA (équipe CHEMBIO) qui soutient sa thèse:
« Synthèse de complexes d’or anticancéreux à ligands hémilabiles : relation structure-réactivité, spéciation et mode d’action »
📅 Mardi 23 octobre 2026, ⏰14:00
✨Journée importante pour Tom LACOMA (équipe CHEMBIO) qui soutient sa thèse:
« Synthèse de complexes d’or anticancéreux à ligands hémilabiles : relation structure-réactivité, spéciation et mode d’action »
📅 Mardi 23 octobre 2026, ⏰14:00
October 15, 2026 at 5:43 PM
Really enjoyed helping put this together with the great team at @cp-cellchembiol.bsky.social and all of the excellent contributors from our PTM chemical biology community! #ptm #chembio
The October issue of Cell Chemical Biology is a special issue on post-translational modifications with guest editor @gburslem.bsky.social. Click to read reviews & more on the ways PTMs increase proteoform diversity & add a versatile regulatory layer to protein function. www.cell.com/cell-chemica...
October 15, 2026 at 4:48 PM
Really enjoyed helping put this together with the great team at @cp-cellchembiol.bsky.social and all of the excellent contributors from our PTM chemical biology community! #ptm #chembio
October 14, 2026 at 9:57 PM
October 14, 2026 at 9:47 PM
October 14, 2026 at 6:18 PM
Inspiring ICBS Global Lectureship Award lecture by Peng Chen at #ICBS2026.
He gave exciting insights into the power of genetic code expansion to better understand PTMs and to enable new chemistry in living cells.
www.cell.com/cell/fulltex...
#Protein #PTM #ChemBio #ChemSky #GeneticCodeExpansion
He gave exciting insights into the power of genetic code expansion to better understand PTMs and to enable new chemistry in living cells.
www.cell.com/cell/fulltex...
#Protein #PTM #ChemBio #ChemSky #GeneticCodeExpansion
October 15, 2026 at 12:41 AM
Inspiring ICBS Global Lectureship Award lecture by Peng Chen at #ICBS2026.
He gave exciting insights into the power of genetic code expansion to better understand PTMs and to enable new chemistry in living cells.
www.cell.com/cell/fulltex...
#Protein #PTM #ChemBio #ChemSky #GeneticCodeExpansion
He gave exciting insights into the power of genetic code expansion to better understand PTMs and to enable new chemistry in living cells.
www.cell.com/cell/fulltex...
#Protein #PTM #ChemBio #ChemSky #GeneticCodeExpansion
Exciting talk by Evan Miller at #ICBS2026.
He talked about his group's work on novel NIR fluorophores based on bis(trifluoromethyl)carborhodamine and their application for live cell microscopy and activity-based sensing.
pubs.acs.org/jacsat/artic...
#Fluorescence #ChemBio #ChemSky #Science
He talked about his group's work on novel NIR fluorophores based on bis(trifluoromethyl)carborhodamine and their application for live cell microscopy and activity-based sensing.
pubs.acs.org/jacsat/artic...
#Fluorescence #ChemBio #ChemSky #Science
October 14, 2026 at 6:32 PM
Exciting talk by Evan Miller at #ICBS2026.
He talked about his group's work on novel NIR fluorophores based on bis(trifluoromethyl)carborhodamine and their application for live cell microscopy and activity-based sensing.
pubs.acs.org/jacsat/artic...
#Fluorescence #ChemBio #ChemSky #Science
He talked about his group's work on novel NIR fluorophores based on bis(trifluoromethyl)carborhodamine and their application for live cell microscopy and activity-based sensing.
pubs.acs.org/jacsat/artic...
#Fluorescence #ChemBio #ChemSky #Science
October 14, 2026 at 4:42 PM