#Alkoxyallenes
Yay, another #ChemSci paper on #ChemSky! This one is an enantioselective and diastereoselective Cu-BINAP-catalysed reductive coupling of alkoxyallenes ketones.
November 23, 2024 at 8:50 AM
🧪📖 New publication!

Our Review “Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation” is now available in Adv Synth & Catal. Modern activation modes unlock alkoxyallene reactivity beyond their classical role as C3 synthons.

#OrganicChemistry #Alkoxyallenes #Catalysis
Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are....
advanced.onlinelibrary.wiley.com
August 24, 2026 at 12:02 PM
Here are just some of the articles you can find in the collection online:
"BINAP-CuH-catalysed enantioselective allylation using alkoxyallenes to access 1,2-syn-tert,sec-diols" by Lisa Roy, Rambabu Chegondi et al. (doi.org/10.1039/D4SC...)
BINAP-CuH-catalysed enantioselective allylation using alkoxyallenes to access 1,2-syn-tert,sec-diols
Herein, we present an economical method for highly enantioselective and diastereoselective Cu-BINAP-catalysed reductive coupling of alkoxyallenes with a range of electronically and structurally diverse ketones to afford 1,2-syn-tert,sec-diols, using PMHS as the hydride source. This reductive coupling has als
doi.org
June 6, 2025 at 3:20 PM