#Amphiphiles
And the next couple. The tyranny of proteins is over!!! Long live the amphiphiles!!!
October 17, 2025 at 9:37 PM
Big pleasure to have Sam Safran as our PoL seminar speaker - engaging talk on biological condensates, with intrinsically disordered proteins likely serving as their own amphiphiles (acting like molecular soap), plus 2 days of great discussions
@weizmanninstitute.bsky.social @poldresden.bsky.social
June 17, 2026 at 5:10 PM
Our democratically elected #paperofthemonth is a preprint from the Das research group on simple lipid amphiphiles forming catalytic vesicles that grow, divide, and eventually decay. 👏 #chemsky

chemrxiv.org/engage/chemr...
Simple Lipid Amphiphiles Co-Assemble to Exhibit Growth into Non-Equilibrium Catalytic Vesicles that Generate Osmolytes to Demonstrate Self-Division and Eventually Decay
Compartments seen in diverse length scales across all life forms are kinetically stable as these need energy and matter to sustain spatial organization, enable growth, division and ultimately undergo ...
chemrxiv.org
October 20, 2025 at 12:36 PM
One of the most-viewed PNAS articles in the last week is “Self-reproduction as an autonomous process of growth and reorganization in fully abiotic, artificial and synthetic cells.” Explore the article here: www.pnas.org/doi/10.1073/...

For more trending articles, visit ow.ly/Me2U50SkLRZ.
September 11, 2025 at 3:36 PM
We just published a photoswitchable amphiphile that abruptly assembles into ellipsoids over 1h after the light is switched off! #ozchem #ChemSky

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Photoswitchable Merocyanine‐Amphiphiles with Programmable Self‐Assembly Times
A merocyanine-based amphiphile self-assembles in water to form visible-light-responsive ellipsoids that can be disassembled with visible light and reform abruptly ∼70 minutes after the light is switc...
chemistry-europe.onlinelibrary.wiley.com
August 19, 2025 at 11:32 PM
Émulsion de censure:
- Potentiellement comestible;
- Accompagne agréablement les plats comme les situations politiques;
- Quoi de plus normal que des amphiphiles dans un hémicycle ?
January 14, 2025 at 10:02 AM
Our paper on using small molecules that self-assemble on polymer surfaces to engineer wearable energy harvesters is out today in Science Advances! Learn about how scaling analysis and fundamental soft matter can impact technology. www.science.org/doi/10.1126/...
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters
Molecules that self-organize into slippery planes are used to engineer functional and comfortable energy harvesters.
www.science.org
January 15, 2025 at 10:50 PM
Non ça c'est une parcelle. Une varicelle c'est des molécules amphiphiles acollées de façon sphéroïdales.
January 5, 2026 at 8:25 PM
PhD Opportunity: Peptide-Based Materials

Join a collaborative project with Dutch universities & industry to design novel peptide-based amphiphiles for biomaterials, detergents, and more! 🧪🔬

Apply now! 🔗 www.rug.nl/about-ug/wor...

#PhD #ChemSky #PeptideChemistry #Biomaterials #ResearchOpportunity
Vacatures bij de RUG
www.rug.nl
January 29, 2025 at 11:23 AM
Extract: This project focuses on creating sequence-controlled DNA amphiphiles for therapeutic delivery using solid-phase DNA synthesis. The successful candidate will engage in organic synthesis, physicochemical characterizations, and biological assays.
September 24, 2026 at 9:07 PM
📣Just published in ACS Mater. Lett @pubs.acs.org! In this fantastic collaboration with F. Cougnon we report the Self-Assembly of Nanocubes from Small-Molecule Amphiphiles. Thanks to all members of Cougnon lab and R. Puttreddy. @dquimicauib.bsky.social @uib.cat 👇👇
doi.org/10.1021/acsm...
September 1, 2026 at 3:42 PM
We are happy to announce several open positions:

- PhD on Novel Peptide-Based Amphiphiles

- PhD in the Origin of Homochirality

- PhD on Expanding Prebiotic Chemistry Through Reactivity in Oil Droplets

- Postdoc in Asymmetric Catalysis

Details and how to apply:
www.benferinga.com/vacancies/
Vacancies - Ben Feringa Research Group
Discover our open positions! Join us as a Postdoc in Photopharmacology or a PhD researcher in Energy Storage for Redox Flow Batteries.
www.benferinga.com
February 4, 2025 at 10:40 AM
Check out our new paper on Multidirectional Charge Separation in Self-Assembled Supra-Amphiphiles, highlithing aggregates which resemble core-principles of artificial photosynthesis.

A great collaboration with Hirsch-group by Elena Mack

doi.org/10.1002/anie...
Multidirectional Charge Separation in Self‐Assembled Aggregates of Perylenebisimide‐Porphyrin Bola‐Supra‐Amphiphiles
Stable aggregates of a new hydrogen-bond mediated porphyrin-perylenebisimide (PBI) bola-type supra-amphiphile have been synthesized by lyophilization of solutions of both single molecules in THF/wate...
doi.org
February 9, 2026 at 9:01 AM
NASA Research Shows Path Toward Protocells on Titan

Cell-like compartments called vesicles could form naturally in the lakes of Saturn’s moon, based on our current knowledge of the moon’s atmosphere and chemistry.

➡️ science.nasa.gov/science-rese...
➡️ doi.org/10.1017/S147... 🧪🔭 #astrobiology
July 15, 2025 at 7:07 AM
💥RSC CNN Paper of the Week💥

Nano onions based on an amphiphilic Au3(pyrazolate)3 complex

Severin* (EPFL)
Solea et al, Nanoscale, 10.1039/D4NR03901G

#ChemSky #Science #NanoSky
Nano onions based on an amphiphilic Au3(pyrazolate)3 complex
Multilayer vesicles with an onion-like architecture can form by self-assembly of organic amphiphiles such as dendrimers, small-molecule surfactants, and block copolymers. Thus far, there are limited r...
doi.org
December 3, 2024 at 4:53 PM
Don't miss this #OpenAccess review by Vânia I. B. Castro, Rui L. Reis, Ricardo A. Pires and Iva Pashkuleva

"Bioinspired helical systems with defined chirality assembled from discrete peptide and glycan amphiphiles"

Read the full review here 👇
Bioinspired helical systems with defined chirality assembled from discrete peptide and glycan amphiphiles
Molecular helices are ubiquitous in biological systems and play key roles in life functions such as recognition, coding and transferring information, replication, catalytic activity, among others. They can have different handedness and dimensions from molecular to macroscale but the exact mechanisms for their forma
pubs.rsc.org
August 19, 2025 at 2:56 PM
Our latest review on "Bioinspired helical systems with defined chirality assembled from discrete peptide and glycan amphiphiles" is out. Check it here: pubs.rsc.org/en/content/a... 3Bs @uminho.bsky.social Vania I. B. Castro Rui L. Reis @pashkuleva.bsky.social @chemsocrev.rsc.org
Bioinspired helical systems with defined chirality assembled from discrete peptide and glycan amphiphiles
Molecular helices are ubiquitous in biological systems and play key roles in life functions such as recognition, coding and transferring information, replication, catalytic activity, among others. The...
pubs.rsc.org
August 15, 2025 at 7:18 PM
Our first endeavour into transient supramolecular polymers is now out in Small! #Chemsky Read the work we have done in the temporal control of superstructure formation (open access) ⬇️ 📖 onlinelibrary.wiley.com/doi/10.1002/...
Thanks for supporting our work @erc.europa.eu !
ATP‐Regulated Formation of Transient Peptide Amphiphiles Superstructures
This work reports the formation of peptide amphiphile bundled superstructures through ATP-driven charge screening. The transient nature of these hierarchical self-assembled nanostructures is regulate....
onlinelibrary.wiley.com
February 28, 2025 at 7:54 AM
Had a great time at the 9th National Gateway NMR Symposium! Didn’t get to dive into our work on cartilage regeneration using peptide amphiphiles from The Stupp Lab at Northwestern—but NMR has been critical in revealing how supramolecular dynamics drive function in these biomaterials. #NMRChat
May 18, 2025 at 9:06 PM
Check out our new paper on amorphous peptide amphiphiles for viral gene delivery! Big shout-out to Julia La Roche, Dr. Clarissa Read and the team.
📄 Find the paper here: onlinelibrary.wiley.com/doi/10.1002/...
August 15, 2025 at 8:32 PM
Design, Synthesis, and Application of Triazole-embedded Maltose-neopentyl-glycol (TMNG) Amphiphiles for Membrane Protein Studies
#glycotime #CarbohydrateResearch
Design, Synthesis, and Application of Triazole-embedded Maltose-neopentyl-glycol (TMNG) Amphiphiles for Membrane Protein Studies
S0008621525001867
www.sciencedirect.com
June 15, 2025 at 2:50 PM
🎉 Paper of the Year 2025 from the RSC CNN

🏆 Nano-onions based on an amphiphilic Au₃(pyrazolate)₃ complex

👏 Congratulations to Atena B. Solea, Davide Dermutas, Farzaneh Fadaei-Tirani, Luigi Leanza, Massimo Delle Piane, Giovanni M. Pavan, and Kay Severin.

#chemsky #nanosky

👏 👏 👏 to the authors
Nano onions based on an amphiphilic Au3(pyrazolate)3 complex
Multilayer vesicles with an onion-like architecture can form by self-assembly of organic amphiphiles such as dendrimers, small-molecule surfactants, and block copolymers. Thus far, there are limited r...
pubs.rsc.org
December 19, 2025 at 3:59 PM
S. Cataldini (U. of Siena) captivated our audience with his presentation on the Development of artificial amphiphiles featuring light-switching and fluorescent properties for modulation of membrane permeability. Exciting research on smart materials and membrane dynamics! @costprogramme.bsky.social
May 4, 2026 at 11:04 AM
Self-reproduction as an autonomous process of growth and reorganization in fully abiotic, artificial and synthetic cells 🧪
www.pnas.org/doi/abs/10.1...

This process mimics key aspects of living systems, offering a path for developing a broad class of abiotic, life-like systems.
August 7, 2025 at 1:32 PM