Excellent work modelling effect of ER visit in patients with out-patient hyperkalemia
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
Emergency department referral and short-term death after outpatient hyperkalemia: a population-based study
Background:Hyperkalemia can be deadly, yet clinical decision-making for outpatient management is unclear. We sought to determine whether an emergency department encounter within 24 hours of a severe o...
www.cmaj.ca
September 13, 2026 at 5:22 PM
Excellent work modelling effect of ER visit in patients with out-patient hyperkalemia
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
What do #livingkidneydonors feel is the most difficult part of donating a kidney? Find out this and more in the link below 👇 #CanadianResearch #organdonation #AskRenal
doi.org/10.1177/2054...
doi.org/10.1177/2054...
August 10, 2026 at 1:20 PM
What do #livingkidneydonors feel is the most difficult part of donating a kidney? Find out this and more in the link below 👇 #CanadianResearch #organdonation #AskRenal
doi.org/10.1177/2054...
doi.org/10.1177/2054...
Any experience with generic budesonide versus Tarpeyo(targeted release budesonide) for IgA nephropathy? All I can find are proteinuria studies and increased risk of systemic side effects. Blue Cross wants patient to fail generic budesonide for 3 months before approving Tarpeyo. #askrenal
July 21, 2026 at 3:05 PM
Any experience with generic budesonide versus Tarpeyo(targeted release budesonide) for IgA nephropathy? All I can find are proteinuria studies and increased risk of systemic side effects. Blue Cross wants patient to fail generic budesonide for 3 months before approving Tarpeyo. #askrenal
#AskRenal
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
July 13, 2026 at 10:44 AM
#AskRenal
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
How do Canadian pediatric nephrologists approach 2025 #KDIGO pediatric nephrotic syndrome recommendations? A Canadian National Survey reviews below👇 #pediatricnephrology #AskRenal #NephSky @csnscn.bsky.social @kdigo.org
doi.org/10.1177/2054...
doi.org/10.1177/2054...
June 2, 2026 at 1:38 PM
How do Canadian pediatric nephrologists approach 2025 #KDIGO pediatric nephrotic syndrome recommendations? A Canadian National Survey reviews below👇 #pediatricnephrology #AskRenal #NephSky @csnscn.bsky.social @kdigo.org
doi.org/10.1177/2054...
doi.org/10.1177/2054...
Help me out here. Why on earth do we have these two conditions when the second encapsulates the first?
Can you have 3 events in 12 month without 2 of them being within a span of 6 months??!!
#askrenal
Can you have 3 events in 12 month without 2 of them being within a span of 6 months??!!
#askrenal
April 23, 2026 at 12:10 AM
Help me out here. Why on earth do we have these two conditions when the second encapsulates the first?
Can you have 3 events in 12 month without 2 of them being within a span of 6 months??!!
#askrenal
Can you have 3 events in 12 month without 2 of them being within a span of 6 months??!!
#askrenal
Quick question - if I want to give Cefoperazone-Sulbactam for IP antibiotics for Automated PD with 10L exchanges can I use the Cefoperazone data in ISPD guidelines ie 500mg/L loading with 125mg/L for maintainence or is that overkill? #AskRenal
April 21, 2026 at 2:27 AM
Quick question - if I want to give Cefoperazone-Sulbactam for IP antibiotics for Automated PD with 10L exchanges can I use the Cefoperazone data in ISPD guidelines ie 500mg/L loading with 125mg/L for maintainence or is that overkill? #AskRenal
Since atrasentan is bound to be approved for use in IgAN, does anyone know whether it will be revived for DKD?
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
April 5, 2026 at 6:14 AM
Since atrasentan is bound to be approved for use in IgAN, does anyone know whether it will be revived for DKD?
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
Has any hospital instituted a reporting requirement that the eGFR cannot be reported if there is a rapid change in creatinine over a short period of time? Feels like it would reduce errors in drug dosing and aid with decision-making
#askrenal
#askrenal
March 5, 2026 at 1:16 AM
Has any hospital instituted a reporting requirement that the eGFR cannot be reported if there is a rapid change in creatinine over a short period of time? Feels like it would reduce errors in drug dosing and aid with decision-making
#askrenal
#askrenal
Requiring a test 2-3 weeks after starting an SGLT2i and then dealing with the (expected yet surprising!!) eGFR drop
-> underprescription and unnecessary discontinuation.
Checking should be limited (high risk eg vol issues or if symptoms).
What guidance can we give our trainees? #askrenal
-> underprescription and unnecessary discontinuation.
Checking should be limited (high risk eg vol issues or if symptoms).
What guidance can we give our trainees? #askrenal
March 1, 2026 at 11:56 AM
Requiring a test 2-3 weeks after starting an SGLT2i and then dealing with the (expected yet surprising!!) eGFR drop
-> underprescription and unnecessary discontinuation.
Checking should be limited (high risk eg vol issues or if symptoms).
What guidance can we give our trainees? #askrenal
-> underprescription and unnecessary discontinuation.
Checking should be limited (high risk eg vol issues or if symptoms).
What guidance can we give our trainees? #askrenal
#askrenal @nephjc.bsky.social have a young male with multisystem sarcoid. Eyes, liver, hilar LNs and interstitial nephritis. Granulomas so big you could pick them out without magnification on histo slide! Any experience of anti TNF as steroid sparing for renal involvement?
February 20, 2026 at 1:34 PM
#askrenal @nephjc.bsky.social have a young male with multisystem sarcoid. Eyes, liver, hilar LNs and interstitial nephritis. Granulomas so big you could pick them out without magnification on histo slide! Any experience of anti TNF as steroid sparing for renal involvement?
In a patient suspected to have PA, with high aldosterone, could discrepancy between direct renin measurement (increased) and PRA (lower norm) be caused by a beta-blocker? Re RAS inhibition, no direct renin inhibitor, only ARB in the medication. Thank you! #askrenal
February 14, 2026 at 10:08 PM
In a patient suspected to have PA, with high aldosterone, could discrepancy between direct renin measurement (increased) and PRA (lower norm) be caused by a beta-blocker? Re RAS inhibition, no direct renin inhibitor, only ARB in the medication. Thank you! #askrenal
#Cardioprotective intradialytic exercise training may protect against hemodialysis-induced myocardial stunning, and improve patient-important outcomes #patientcare #AskRenal @umanitoba.bsky.social @csnscn.bsky.social
doi.org/10.1177/2054...
doi.org/10.1177/2054...
February 2, 2026 at 2:11 PM
#Cardioprotective intradialytic exercise training may protect against hemodialysis-induced myocardial stunning, and improve patient-important outcomes #patientcare #AskRenal @umanitoba.bsky.social @csnscn.bsky.social
doi.org/10.1177/2054...
doi.org/10.1177/2054...
Patient on Automated PD presents with hypotension, abdominal pain , fever for 2 days. Symptoms developed after colonoscopy with polypectomy.
October 31, 2025 at 3:11 PM
Apart from myeloma and MGRS , what other diseases should we think of in case of increased UPCR with no albumunuria in urine analysis.
Urine alb- trace
UPCR-5.2
SIFE,SFLC - normal
@askrenal.bsky.social #askrenal
#Nephsky
Urine alb- trace
UPCR-5.2
SIFE,SFLC - normal
@askrenal.bsky.social #askrenal
#Nephsky
October 23, 2025 at 12:44 PM
Apart from myeloma and MGRS , what other diseases should we think of in case of increased UPCR with no albumunuria in urine analysis.
Urine alb- trace
UPCR-5.2
SIFE,SFLC - normal
@askrenal.bsky.social #askrenal
#Nephsky
Urine alb- trace
UPCR-5.2
SIFE,SFLC - normal
@askrenal.bsky.social #askrenal
#Nephsky
My initial thoughts about aldosterone synthase inhibitors: why spend $$$$ to achieve what $4 of spironolactone can also achieve? Am I missing something?
#askrenal
#askrenal
October 19, 2025 at 4:49 AM
My initial thoughts about aldosterone synthase inhibitors: why spend $$$$ to achieve what $4 of spironolactone can also achieve? Am I missing something?
#askrenal
#askrenal
Curious to know what North American folks think about whether a drop in BP will be enough to get Baxdrostat licensed? In UK suspect NICE will want to see MACE data first to do cost-effectiveness analysis. #medsky #askrenal #nephjc
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | NEJM
Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension.
In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated
systolic blood pr...
www.nejm.org
October 11, 2025 at 5:50 AM
October 9, 2025 at 9:47 PM
If a patient is overloaded and their potassium is not an issue, do you usually do a isolated UF in the beginning or at the end of the dialysis session? Why?
#AskRenal
#AskRenal
October 3, 2025 at 6:44 PM
If a patient is overloaded and their potassium is not an issue, do you usually do a isolated UF in the beginning or at the end of the dialysis session? Why?
#AskRenal
#AskRenal
In patients with antiHBc total positivity with negative DNA, do you use rituximab (eg AAV) with HBV prophylaxis as a safe alternative? Thank you #askrenal
September 27, 2025 at 6:24 AM
In patients with antiHBc total positivity with negative DNA, do you use rituximab (eg AAV) with HBV prophylaxis as a safe alternative? Thank you #askrenal