The adoption of azole fungicides by agriculture has led to azole resistance distributing in fungi throughout the world and defeating the antifungal action of azoles in medicine. Which is, to be clear, bad.
November 8, 2024 at 12:52 PM
The adoption of azole fungicides by agriculture has led to azole resistance distributing in fungi throughout the world and defeating the antifungal action of azoles in medicine. Which is, to be clear, bad.
New in Nature Comms, we show that azole-resistant Aspergillus fumigatus are more likely to evolve resistance to new antifungals due to variants in their DNA mismatch repair system rdcu.be/d3Iyc @natureportfolio.bsky.social #microsky #fungi #amr
Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance
Nature Communications - Here, Bottery et al show that resistance to next generation antifungals is more likely to occur within azole resistant Aspergillus fumigatus due to the close linkage between...
rdcu.be
December 16, 2024 at 12:04 PM
New in Nature Comms, we show that azole-resistant Aspergillus fumigatus are more likely to evolve resistance to new antifungals due to variants in their DNA mismatch repair system rdcu.be/d3Iyc @natureportfolio.bsky.social #microsky #fungi #amr
Finally out!
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen
journals.asm.org/doi/10.1128/...
A big thanks to @danielcroll.bsky.social & @GabrielScalliet
#azole #DMI #GWAS #fungicide #resistance #zymoseptoria #Europe
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen
journals.asm.org/doi/10.1128/...
A big thanks to @danielcroll.bsky.social & @GabrielScalliet
#azole #DMI #GWAS #fungicide #resistance #zymoseptoria #Europe
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen | mBio
Sustainable food production requires the management of disease agents attacking crops.
Application of antifungal compounds is among the key elements of pathogen containment;
however, resistance can ri...
journals.asm.org
December 1, 2025 at 12:00 AM
Finally out!
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen
journals.asm.org/doi/10.1128/...
A big thanks to @danielcroll.bsky.social & @GabrielScalliet
#azole #DMI #GWAS #fungicide #resistance #zymoseptoria #Europe
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen
journals.asm.org/doi/10.1128/...
A big thanks to @danielcroll.bsky.social & @GabrielScalliet
#azole #DMI #GWAS #fungicide #resistance #zymoseptoria #Europe
Widespread use of azole fungicides in agriculture may reduce the effectiveness of antifungal treatments for patients with aspergillosis. EMA highlights that nearly all 120,000 tonnes of azoles sold in the EU were used as pesticides, potentially contributing to #AMR
www.ema.europa.eu/en/news/one-...
www.ema.europa.eu/en/news/one-...
One Health: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi | European Medicines Agency (EMA)
The extensive use of azole fungicides (azoles), particularly in some agricultural and horticultural practices, can increase the risk of Aspergillus fungi developing resistance to essential antifungal ...
www.ema.europa.eu
January 31, 2025 at 9:26 AM
Widespread use of azole fungicides in agriculture may reduce the effectiveness of antifungal treatments for patients with aspergillosis. EMA highlights that nearly all 120,000 tonnes of azoles sold in the EU were used as pesticides, potentially contributing to #AMR
www.ema.europa.eu/en/news/one-...
www.ema.europa.eu/en/news/one-...
Antagonistic interaction between posaconazole & olorofim in a murine model of invasive pulmonary aspergillosis
Posaconazole ⬇️ the effect of olorofim in vivo. Combination of olorofim+azole likely efficacious in wt infections, may be suboptimal in azole R infections
academic.oup.com/jac/article/...
Posaconazole ⬇️ the effect of olorofim in vivo. Combination of olorofim+azole likely efficacious in wt infections, may be suboptimal in azole R infections
academic.oup.com/jac/article/...
Antagonistic interaction between posaconazole and olorofim in a murine model of invasive pulmonary aspergillosis
AbstractBackground. Olorofim is a new antifungal agent with a novel mechanism of action with in vitro activity against Aspergillus fumigatus and other clin
academic.oup.com
September 24, 2025 at 6:35 PM
Antagonistic interaction between posaconazole & olorofim in a murine model of invasive pulmonary aspergillosis
Posaconazole ⬇️ the effect of olorofim in vivo. Combination of olorofim+azole likely efficacious in wt infections, may be suboptimal in azole R infections
academic.oup.com/jac/article/...
Posaconazole ⬇️ the effect of olorofim in vivo. Combination of olorofim+azole likely efficacious in wt infections, may be suboptimal in azole R infections
academic.oup.com/jac/article/...
#JustPublished!
#OneHealth: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi.
Joint report by: @ecdc.europa.eu, @efsa.europa.eu, @ema.europa.eu, @euchemicalsagency.bsky.social, #EEA and @ec.europa.eu's Joint Research Centre
Read full here: bit.ly/3CH77ts
#Azoles
#OneHealth: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi.
Joint report by: @ecdc.europa.eu, @efsa.europa.eu, @ema.europa.eu, @euchemicalsagency.bsky.social, #EEA and @ec.europa.eu's Joint Research Centre
Read full here: bit.ly/3CH77ts
#Azoles
One Health: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi
The extensive use of azole fungicides (azoles), particularly in some agricultural and horticultural practices, can increase the risk of Aspergillus fungi developing resistance to essential antifungal ...
bit.ly
January 30, 2025 at 10:38 AM
#JustPublished!
#OneHealth: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi.
Joint report by: @ecdc.europa.eu, @efsa.europa.eu, @ema.europa.eu, @euchemicalsagency.bsky.social, #EEA and @ec.europa.eu's Joint Research Centre
Read full here: bit.ly/3CH77ts
#Azoles
#OneHealth: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi.
Joint report by: @ecdc.europa.eu, @efsa.europa.eu, @ema.europa.eu, @euchemicalsagency.bsky.social, #EEA and @ec.europa.eu's Joint Research Centre
Read full here: bit.ly/3CH77ts
#Azoles
5 EU agencies – @efsa.europa.eu, @ecdc.europa.eu, European Chemicals Agency, European Environment Agency & EMA - reviewed how the use of azole substances outside human medicine increases the risk of a very common fungi becoming resistant to existing treatment. www.ema.europa.eu/en/news/one-...
January 30, 2025 at 10:57 AM
5 EU agencies – @efsa.europa.eu, @ecdc.europa.eu, European Chemicals Agency, European Environment Agency & EMA - reviewed how the use of azole substances outside human medicine increases the risk of a very common fungi becoming resistant to existing treatment. www.ema.europa.eu/en/news/one-...
if u were a mold active azole which would u be
July 11, 2026 at 6:01 PM
if u were a mold active azole which would u be
OI
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
130. Azole Antifungals
Podcast Episode · ID:IOTS - Infectious Disease Insight Of Two Specialists · 26/01/2026 · 32m
podcasts.apple.com
January 27, 2026 at 6:37 PM
OI
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
YOU
… Podcast on Azole Antifungals.
Would be a shame if you reposted it to AAAAAAALLL your followers, and liked it and commented on what you thought of it below
PLEASE DON’T DO THAT we hate popularity!!
#IDsky #microsky #fungi
podcasts.apple.com/gb/podcast/i...
Together with the #OneHealth #EUAgencies and the @ec.europa.eu's Joint Research Centre, we conclude that extensive use of #azole #fungicides, for example in #biocides, can increase the risk of antifungal resistance threatening #publichealth.
Read the news: t.co/aX1v2nHERY
Read the news: t.co/aX1v2nHERY
Resistance to azole fungicides in Aspergillus
YouTube video by EFSAchannel
www.youtube.com
February 24, 2025 at 12:59 PM
Together with the #OneHealth #EUAgencies and the @ec.europa.eu's Joint Research Centre, we conclude that extensive use of #azole #fungicides, for example in #biocides, can increase the risk of antifungal resistance threatening #publichealth.
Read the news: t.co/aX1v2nHERY
Read the news: t.co/aX1v2nHERY
The next pathogen of concern is azole resistant Candida Auris.
July 24, 2026 at 3:32 PM
The next pathogen of concern is azole resistant Candida Auris.
So, I am curious what people do do histo meningitis.
After the ampho, what azole do people use?
After the ampho, what azole do people use?
December 7, 2024 at 1:54 PM
So, I am curious what people do do histo meningitis.
After the ampho, what azole do people use?
After the ampho, what azole do people use?
Die Wirkstoffgruppe der Azole die wir in mg-Menge als Medikamente einsetzen werden in der Landwirtschaft großflächig eingesetzt
1 ha Weizen ~ 1 -2l Fungizid
Teils mehrfach im Jahr
Mehrere Krankenhäuser kämpfen mittlerweile gegen resistenten candida auris
1 ha Weizen ~ 1 -2l Fungizid
Teils mehrfach im Jahr
Mehrere Krankenhäuser kämpfen mittlerweile gegen resistenten candida auris
Die Ratgeber : Der 'neue' Pilz: Candida auris - hier anschauen
Candida auris, der 'neue' Pilz klingt exotisch und harmlos. Dabei handelt es sich um einen gefährlichen Krankheitserreger. Erstmals wurde der Hefepilz 2009 in Japan entdeckt. Inzwischen tritt der Pilz...
www.ardmediathek.de
December 20, 2025 at 6:30 PM
Die Wirkstoffgruppe der Azole die wir in mg-Menge als Medikamente einsetzen werden in der Landwirtschaft großflächig eingesetzt
1 ha Weizen ~ 1 -2l Fungizid
Teils mehrfach im Jahr
Mehrere Krankenhäuser kämpfen mittlerweile gegen resistenten candida auris
1 ha Weizen ~ 1 -2l Fungizid
Teils mehrfach im Jahr
Mehrere Krankenhäuser kämpfen mittlerweile gegen resistenten candida auris
November 18, 2024 at 3:26 PM
Together with the #OneHealth EU Agencies & @ec.europa.eu's Joint Research Centre, we've published a report on azole fungicide resistance.
The broad use of azoles, particularly in agriculture, risks making key treatments ineffective, threatening #PublicHealth.
🌱🦠 Learn more: europa.eu/!DkNp7f
The broad use of azoles, particularly in agriculture, risks making key treatments ineffective, threatening #PublicHealth.
🌱🦠 Learn more: europa.eu/!DkNp7f
One Health: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi
For the first time, the five EU health and environment agencies – EFSA, ECDC, ECHA, EEA and EMA[1]– supported by the JRC, reviewed how the use of azole substances outside human medicine affects public...
europa.eu
January 30, 2025 at 10:05 AM
Together with the #OneHealth EU Agencies & @ec.europa.eu's Joint Research Centre, we've published a report on azole fungicide resistance.
The broad use of azoles, particularly in agriculture, risks making key treatments ineffective, threatening #PublicHealth.
🌱🦠 Learn more: europa.eu/!DkNp7f
The broad use of azoles, particularly in agriculture, risks making key treatments ineffective, threatening #PublicHealth.
🌱🦠 Learn more: europa.eu/!DkNp7f
Dr. Dominique Monnet from @ecdc.europa.eu, explains how azole fungicides in agriculture are contributing to resistance in Aspergillus fumigatus, making infections harder to treat. #IDsky #MEDsky
Read here: www.contagionlive.com/view/azole-f...
Read here: www.contagionlive.com/view/azole-f...
Azole Fungicides in Agriculture Linked to Rising Resistance in Aspergillus fumigatus
European agencies warn that non-medical fungicide use may be fueling resistance in A fumigatus, a mold responsible for severe human infections.
www.contagionlive.com
February 5, 2025 at 2:00 PM
Dr. Dominique Monnet from @ecdc.europa.eu, explains how azole fungicides in agriculture are contributing to resistance in Aspergillus fumigatus, making infections harder to treat. #IDsky #MEDsky
Read here: www.contagionlive.com/view/azole-f...
Read here: www.contagionlive.com/view/azole-f...
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen https://www.biorxiv.org/content/10.1101/2025.03.19.644200v1
March 20, 2025 at 4:16 AM
A large European diversity panel reveals complex azole fungicide resistance gains of a major wheat pathogen https://www.biorxiv.org/content/10.1101/2025.03.19.644200v1
Congratulation to @mbottery.bsky.social for getting his paper on elevated mutation rates in Aspergillus fumigatus out in Nature Communications today! www.nature.com/articles/s41...
Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance - Nature Communications
Here, Bottery et al show that resistance to next generation antifungals is more likely to occur within azole resistant Aspergillus fumigatus due to the close linkage between a globally distributed azo...
www.nature.com
December 16, 2024 at 11:31 AM
Congratulation to @mbottery.bsky.social for getting his paper on elevated mutation rates in Aspergillus fumigatus out in Nature Communications today! www.nature.com/articles/s41...
For the first time, the #OneHealth
and environment agencies – @efsa.europa.eu, @ecdc.europa.eu, @ema.europa.eu, @eea.europa.eu & @echa.europa.eu- partnered with the
EU Join Research Center to publish findings on #azole #fungicide resistance and its #PublicHealth impact.
🔗 fcld.ly/fungipressre...
and environment agencies – @efsa.europa.eu, @ecdc.europa.eu, @ema.europa.eu, @eea.europa.eu & @echa.europa.eu- partnered with the
EU Join Research Center to publish findings on #azole #fungicide resistance and its #PublicHealth impact.
🔗 fcld.ly/fungipressre...
February 24, 2025 at 1:15 PM
For the first time, the #OneHealth
and environment agencies – @efsa.europa.eu, @ecdc.europa.eu, @ema.europa.eu, @eea.europa.eu & @echa.europa.eu- partnered with the
EU Join Research Center to publish findings on #azole #fungicide resistance and its #PublicHealth impact.
🔗 fcld.ly/fungipressre...
and environment agencies – @efsa.europa.eu, @ecdc.europa.eu, @ema.europa.eu, @eea.europa.eu & @echa.europa.eu- partnered with the
EU Join Research Center to publish findings on #azole #fungicide resistance and its #PublicHealth impact.
🔗 fcld.ly/fungipressre...
Impact of the use of azole fungicides, other than as human medicines, on the development of azole-resistant Aspergillus spp. efsa.onlinelibrary.wiley.com/doi/full/10....
Impact of the use of azole fungicides, other than as human medicines, on the development of azole‐resistant Aspergillus spp.
The use of azoles in the European Union and European Economic Area (EU/EEA) other than as human medicines has raised concerns about emergence and spread of azole-resistant Aspergillus species. EU age...
efsa.onlinelibrary.wiley.com
January 31, 2025 at 12:29 PM
Impact of the use of azole fungicides, other than as human medicines, on the development of azole-resistant Aspergillus spp. efsa.onlinelibrary.wiley.com/doi/full/10....
Dr Barber describes how genomic epidemiology was used to establish clonal spread of azole resistant C parapsilosis through hospitals in Berlin
March 21, 2026 at 9:23 PM
Dr Barber describes how genomic epidemiology was used to establish clonal spread of azole resistant C parapsilosis through hospitals in Berlin