#BOLD-Signal
My search for blue skies and safer pastures doesn’t in any way signal that I’m giving up the fight against what drove us away from our former online community. So, hello fellow seekers! I am here! Our work continues. Let’s be bold and joyful. #HappyThanksgiving!
November 28, 2024 at 4:53 PM
For generations, people around the world have used color to show collective strength in the face of oppression. The #NoKings movement is no different. Yellow is our shared signal, bright, bold and impossible to ignore, a reminder that America's power belongs to our people, not to kings.
October 18, 2025 at 11:09 AM
The BOLD signal may not be what we thought it was.
BOLD signal changes can oppose oxygen metabolism across the human cortex
www.nature.com/articles/s41...
#neuroscience
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
December 20, 2025 at 3:41 PM
fMRI signals “up,” but neural metabolism might be going “down.”

In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.

rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
December 16, 2025 at 3:43 PM
Yes, the religious freedom implications are extremely worrying and signal that we are indeed entering a theocracy, but also I am of the bold opinion that official policy should never be pro-Armageddon.
March 3, 2026 at 7:31 PM
Yeah, this guy sped to the very end of the onramp lane and then just turned into traffic with no signal.

It was a bold move!
May 29, 2024 at 12:36 PM
Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.

www.nature.com/articles/s41...
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
January 5, 2026 at 11:55 AM
I think this signal story will stick around more than people are expecting precisely because it's this compelling to journalists. It'll also make other journalists a lot more bold about attempts to work their way in
man as a journalist this is the kind of thing you might childishly fantasize about while mowing the lawn or waking up from a dream
In 25 years of covering national security, I’ve never seen a story like this: Senior Trump officials discussed planning for the U.S. attack on Yemen in a Signal group--and inadvertently added the editor-in-chief of The Atlantic. www.theatlantic.com/politics/arc...
March 24, 2025 at 7:28 PM
BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...
October 22, 2025 at 12:41 AM
For this #FlowersOnFriday, a tribute to the most beautiful Bearded Iris that ever fell victim to our winter damp clay soil. Thanks for the memories, friend! #bloomscrolling #gardening #joy #photography 🌱
January 24, 2025 at 2:56 PM
The Trump Administration’s use of Signal is a bold strategy that harkens back to our forefathers.
March 25, 2025 at 4:07 PM
Winner winner.

@analiliafornj.bsky.social helped build the Working Families Party in New Jersey. Now her victory sends a clear signal that it’s a new day in New Jersey politics, and our country is ready for bold, working-class leadership. Let's talk about it:
February 10, 2026 at 8:24 PM
A woman in protest. Bra raised. Unapologetic. 1960s fire.
The June 6–10 General Strike draws from that same spirit—bold, disruptive, defiant.
Just a signal boost...

#GeneralStrike #ShieldOfResistance #June6to10 #WorkersUnite #FeministStrike
May 17, 2025 at 2:42 PM
@zackpolanski.bsky.social says the country needs bold transformative policies not tinkering at the edges and if Burnham is prepared to do them he'll work with the govt, "but every signal we're seeing so far is actually they're going to do the opposite & more of the failed status quo"
July 17, 2026 at 7:11 AM
CANADA REJECTS BOTH US BIDS – Picks SWEDISH GlobalEye on CANADIAN Airframe, Boeing Completely OUT!
In a stunning move, Canada just rejected Boeing and L3Harris to choose Saab’s GlobalEye built on a Bombardier jet made in Montreal. No American parts, no US tech — a bold signal of shifting alliances.
May 30, 2026 at 1:21 AM
To a neuroscientist with a hammer, everything is a bold signal
February 21, 2026 at 12:39 PM
September 27, 2025 at 3:59 PM
"About 40% of voxels with significant BOLD signal changes during various tasks showed reversed oxygen metabolism, particularly in the default mode network... Our findings challenge the canonical interpretation of the BOLD signal" pubmed.ncbi.nlm.nih.gov/41402521/ A BOLD challenge #fmri
December 20, 2025 at 10:06 AM
BOLD signal changes can oppose oxygen metabolism across the human cortex

Nature Neuroscience (2025)
#neuroskyence

www.nature.com/articles/s41...
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
December 28, 2025 at 11:14 AM
On Nov. 5, 1939, the National Research Council began to broadcast the Time Signal.
The signal was broadcast every day for the next 84 years, technically making it the one of the longest-running radio segments in Canadian history.
This is the story of the Time Signal.

🧵 1/5
November 5, 2025 at 2:02 PM
SIGNAL, THE BOARD GAME!

Can you navigate high-stakes military calls without a security leak? Play SIGNAL, the strategy game where you make bold decisions and try to figure out who shouldn’t be on the line!

Made with @hailuoai.bsky.social
Share/Subscribe: youtu.be/HSY84Ku1NsI
SIGNAL, THE BOARD GAME!
YouTube video by Mr. Newberger's AI Funnies
youtu.be
March 27, 2025 at 12:02 PM
Check out this amazing new work from @giuliaabaracc.bsky.social uncovering mechanisms of brain signal variability! www.biorxiv.org/content/10.1...
The biological role of local and global fMRI BOLD signal variability in human brain organization
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
October 24, 2023 at 4:52 PM
There's a right-wing discourse game, where you try to signal how bold and unwoke you are by saying the worst things imaginable, and there's a left-liberal discourse game, where you try to intuit all the stuff you're expected to believe and try to pithily rephrase it so your friends know you're smart
June 15, 2025 at 5:31 PM
some number of people seem to think that it is good that there is a growing consensus across the political spectrum to do extralegal violence. i am staking out the bold position that this does not signal positive things to come
i don’t think it’s good that my political opponents have a strong desire to commit violent acts on people they dislike actually.
December 9, 2024 at 9:58 PM