#BabyBIG
Wann No killed Cow oder No tortured screaming Babybig von Beyond cruelty?
October 7, 2025 at 4:46 AM
8/ The ByHeart infant formula botulism outbreak has now sickened at least 39 babies nationwide. All were treated with BabyBIG—the only treatment for infant botulism—developed over decades by California’s Infant Botulism Treatment & Prevention Program.
December 12, 2025 at 5:23 PM
Botulism outbreak now at 23 babies, all hospitalized and treated with BabyBIG. No deaths.

Do not use ByHeart infant formulas. #IDSky #botulism

www.cdc.gov/botulism/out...
Investigation Update: Infant Botulism Outbreak, November 2025
Investigation details for an outbreak of infant botulism linked to infant formula, November 2025.
www.cdc.gov
November 17, 2025 at 2:54 PM
6/ The California Dept. of Public Health identified the cluster and is coordinating BabyBIG antitoxin distribution. ByHeart makes just 1% of U.S. formula, so a national shortage is unlikely. Stop using ByHeart formula immediately; retailers should pull it from shelves. Investigations are ongoing.
November 10, 2025 at 11:00 PM
The development and use of BabyBIG, the sole treatment for infant botulism, is "almost like a miracle," a doc who treats these babies told me.
apnews.com/article/infa...
How a rare drug made from scientists' blood saves babies from botulism
An infant botulism outbreak has sickened at least 39 babies across the U.S. and underscored the crucial role of a medication that treats the rare disease.
apnews.com
December 9, 2025 at 2:34 PM
9/ BabyBIG exists thanks to a small CDPH team who literally donated their own antibody-rich blood (since they'd all gotten a botulism vax as scientists working with the bug) to create the first batches. Since 2003, over 3,700 children worldwide have been treated.
December 12, 2025 at 5:23 PM
“The sole treatment for infant botulism is known as BabyBIG, an IV medication made from the pooled blood plasma of adults immunized against botulism. California's infant botulism program developed the product and is the sole source worldwide.”

Kudos to Infant Botulism Treatment & Prevention Program
December 11, 2025 at 6:37 PM
“The first thing to know is that the baby is all right now & coming up on her second birthday…
But her home holds a few clues to her past. An oddly huggable orange stuffed animal shaped like Clostridium botulinum…enshrined in plexiglass, a bottle of BabyBIG, the antitoxin treatment that saved her”
New infant botulism outbreak puts fancy formulas under scrutiny
A new infant botulism outbreak puts fancy formulas that position their products as safer than other options under scrutiny.
www.statnews.com
June 18, 2026 at 11:44 AM
4/ Treatment is actually where California plays a key role in this story, as CDPH runs the only infant botulism treatment program in the world.
Their BabyBIG medication, which is essentially an antibody to the toxin, cuts hospital time in half and saves lives worldwide.
November 14, 2025 at 5:07 PM
Licensed in 2003, BabyBIG is the brand name for human botulism immune globulin, an IV medication that uses antibodies from volunteers vaccinated against botulism to help babies too young to fight the disease on their own.
www.latimes.com/science/stor...
How a rare drug made from scientists' blood saves babies from botulism
An infant botulism outbreak has sickened at least 39 babies across the U.S., underscoring the crucial role of a medication that treats the rare disease.
www.latimes.com
December 10, 2025 at 4:09 AM
“CPDH developed & is the only source of BabyBIG [a human plasma-derived treatment for infants with botulism]…CDC & FDA began their investigation into the outbreak after officials with CPDH's Infant Botulism Treatment & Prevention Program alerted them to an increase in requests for the treatment.”
November 24, 2025 at 11:22 PM
The treatment is called "BabyBIG" (Botulism Immune Globulin).
November 10, 2025 at 8:58 PM
I have only been the one to make the call for BabyBIG once but as I recall there is a single doctor who is on call to approve it being sent out and boy are they busy right now.
November 28, 2025 at 4:51 AM
You can also reach out to the Infant Botulism Treatment and Prevention Program (IBTPP), the sole provider of BabyBIG—Botulism Immune Globulin Intravenous (Human) (BIG-IV), for no-cost 24/7 medical consultation (510-231-7600)
December 29, 2024 at 5:29 PM
@espidsociety.bsky.social
#WMW Day 2 started with One Health PID. Climate and migration will bring broader differential diagnosis that challenge our usual guidelines...
For instance, have you heard of #BabyBIG? Dr. Hill highlighted it in her infant botulism case 👏
#ESPID2026 #CoConnecting
June 3, 2026 at 8:33 AM
My daughter caught infant botulism at 6 weeks old. No one tells you to look out for what seems to be constipation early on before the onset of lethargy, refusal to eat, and hypotonia.

It took about 4-5 days for her to get diagnosed and another day or so to get the BabyBIG flown in from California
We finally got through our formula stash and now this happens. Im a fool for not maintaining the stash
November 9, 2025 at 11:45 PM
BabyBIG, a plasma-derived immune globulin, remains the only approved treatment for infant botulism, relying on antibodies from specially vaccinated donors to help affected infants recover.
How a rare drug made from scientists' blood saves babies from botulism
When Alessandro Barbera was rushed to a California hospital with infant botulism in October, his father had barely heard of the disease, never mind the rare and costly treatment that likely saved the newborn's life.
medicalxpress.com
December 9, 2025 at 6:32 PM
Since as far as I can tell, California CDPH is the ONLY entity that insists on having BabyBIG on hand for IB outbreaks, I suspect THEY are the ones that finally broke the case. Considering, infant formula is a supposed focus of MAHA, they aren't taking lead. 🙄

www.foodsafetynews.com/2025/11/cong...
Congresswoman demands that FDA release all inspection reports on ByHeart infant formula production plants
A U.S. representative is pressing the FDA for information about ByHeart Inc., the company linked to an outbreak of infant botulism poisonings. In a letter
www.foodsafetynews.com
December 13, 2025 at 12:18 AM
BabyBIG
September 1, 2026 at 5:00 AM
September 1, 2026 at 5:00 AM
Fourth baby added to list of Nara Organics victims

The FDA and the CDC are reporting a fourth baby has been added to the list of infant botulism victims linked to Nara Organics Whole Milk Organic Infant Formula. The latest victim is a resident of California. All four of the outbreak victims are…
Fourth baby added to list of Nara Organics victims
The FDA and the CDC are reporting a fourth baby has been added to the list of infant botulism victims linked to Nara Organics Whole Milk Organic Infant Formula. The latest victim is a resident of California. All four of the outbreak victims are male babies ranging in age from 2 to 5 months at onset of illness. All four babies were hospitalized and treated with BabyBIG.
efoodalert.com
July 6, 2026 at 8:53 PM
They will be likely asking why there needs to be anyone consulting with providers for babyBIG, & why can't they just call CA themselves...etc. The ppl making these decisions don't understand how anything works.
February 14, 2025 at 6:59 PM
The bright side is, through all of the horror that trial and error brings, our daughter got the medicine she needed and survived.

BabyBIG works in hours and lasts for about 6-9 months after the fact. At which point the gut is more developed and likelihood of this occurring again is almost zero.
November 9, 2025 at 11:54 PM