boofing mike and ikes because of bioavailability
December 15, 2024 at 7:43 PM
boofing mike and ikes because of bioavailability
ktp doesn’t want you to know that snorting creatine increases bioavailability
June 24, 2026 at 4:32 PM
ktp doesn’t want you to know that snorting creatine increases bioavailability
Fun fact: magnesium oxide is a scam, with like 4% bioavailability. The good stuff, glycinate and citrate and malate are all much more expensive but much higher bioavailability with less laxative effects
August 9, 2024 at 1:16 PM
Fun fact: magnesium oxide is a scam, with like 4% bioavailability. The good stuff, glycinate and citrate and malate are all much more expensive but much higher bioavailability with less laxative effects
oh, "we are cooked?" have you considered tjat cooking increases the bioavailability of certain nutrients?? HMMMM???
April 25, 2025 at 6:59 PM
oh, "we are cooked?" have you considered tjat cooking increases the bioavailability of certain nutrients?? HMMMM???
This lab conducts research on pharmaceutical manufacturing, drug formulation, and characterization. It also provides scientific training to FDA staff on crucial aspects of drug quality and bioavailability/bioequivalence
March 4, 2025 at 11:44 PM
This lab conducts research on pharmaceutical manufacturing, drug formulation, and characterization. It also provides scientific training to FDA staff on crucial aspects of drug quality and bioavailability/bioequivalence
Phytoestrogens have poor bioavailability in humans and you'd have to eat a truly insane amount to cause any endocrinal problems.
October 4, 2025 at 11:35 AM
Phytoestrogens have poor bioavailability in humans and you'd have to eat a truly insane amount to cause any endocrinal problems.
just remember to eat them with something to drink, you need sufficient water for full bioavailability
September 25, 2026 at 3:27 PM
just remember to eat them with something to drink, you need sufficient water for full bioavailability
PKPD BABE
pharmacokinetics (PK)
pharmacodynamics (PD)
bioavailability (BA)
bioequivalence (BE)
🧪 🩺 #PharmSky
pharmacokinetics (PK)
pharmacodynamics (PD)
bioavailability (BA)
bioequivalence (BE)
🧪 🩺 #PharmSky
What would your most nerdy knuckle tats say?
Mine might be: MORE SALT.
Mine might be: MORE SALT.
dad at this playground has knuckle tats that say BOOK WORM, which is a perfect combo of nerdy and badass
June 10, 2024 at 12:22 AM
PKPD BABE
pharmacokinetics (PK)
pharmacodynamics (PD)
bioavailability (BA)
bioequivalence (BE)
🧪 🩺 #PharmSky
pharmacokinetics (PK)
pharmacodynamics (PD)
bioavailability (BA)
bioequivalence (BE)
🧪 🩺 #PharmSky
BUT THE BIOAVAILABILITY LILITH
March 4, 2025 at 6:09 AM
BUT THE BIOAVAILABILITY LILITH
super important point 🤯
TWO factors determine the efficacy of oral antibiotics:
[1] bioavailability
[2] the highest dose you can give orally without provoking GI intolerance
exposure = (dose)(bioavailability)
#EMIMCC
TWO factors determine the efficacy of oral antibiotics:
[1] bioavailability
[2] the highest dose you can give orally without provoking GI intolerance
exposure = (dose)(bioavailability)
#EMIMCC
You’re right, maybe the term isn’t ideal here.
I think they mean oral cipro can maintain exposure thanks to higher doses than IV.
But oral BLs usually mean lower total doses than their IV equivalents (cefazolin 2g/8h, amox/clav 1g/200mg/8h…).
I had a slide on this from a previous ESCMID Global! 😉
I think they mean oral cipro can maintain exposure thanks to higher doses than IV.
But oral BLs usually mean lower total doses than their IV equivalents (cefazolin 2g/8h, amox/clav 1g/200mg/8h…).
I had a slide on this from a previous ESCMID Global! 😉
July 21, 2025 at 1:33 AM
super important point 🤯
TWO factors determine the efficacy of oral antibiotics:
[1] bioavailability
[2] the highest dose you can give orally without provoking GI intolerance
exposure = (dose)(bioavailability)
#EMIMCC
TWO factors determine the efficacy of oral antibiotics:
[1] bioavailability
[2] the highest dose you can give orally without provoking GI intolerance
exposure = (dose)(bioavailability)
#EMIMCC
The rectal bioavailability on this would be INSANE
May 2, 2025 at 12:55 PM
The rectal bioavailability on this would be INSANE
oh you’re telling me girls who finger their assholes every night are into some wacky sexual things? yeah i bet it’s the 12.0056% higher bioavailability of progesterone as reported by respected medical researcher xX_snuffbait_420_Xx on its cohost account
March 4, 2025 at 6:10 AM
oh you’re telling me girls who finger their assholes every night are into some wacky sexual things? yeah i bet it’s the 12.0056% higher bioavailability of progesterone as reported by respected medical researcher xX_snuffbait_420_Xx on its cohost account
Mosquito nets with PFAS may be more effective than environmentally friendly alternatives, new #ScienceAdvances research finds.
Learn more: https://scim.ag/4t4iYqs
Learn more: https://scim.ag/4t4iYqs
Multimodal platform for ITN efficacy: Surface chemistry, bioavailability, and mosquito behavior
Removing PFAS from ITNs compromises insecticide bioavailability and effectiveness, particularly against resistant malaria vectors.
scim.ag
April 10, 2026 at 6:00 PM
Mosquito nets with PFAS may be more effective than environmentally friendly alternatives, new #ScienceAdvances research finds.
Learn more: https://scim.ag/4t4iYqs
Learn more: https://scim.ag/4t4iYqs
Bioavailability impacts a drug's effectiveness and safety profile and how much of the active ingredient reaches the bloodstream and is available at the site of action. Bioequivalence studies show that a cheap generic drug is interchangeable with a brand-name drug. Kinda useful.
March 4, 2025 at 11:44 PM
Bioavailability impacts a drug's effectiveness and safety profile and how much of the active ingredient reaches the bloodstream and is available at the site of action. Bioequivalence studies show that a cheap generic drug is interchangeable with a brand-name drug. Kinda useful.
supercool small-molecule bioavailability science thread
The approval of Wegovy pills for weight loss is getting considerable attention.
There is an important pharmacological aspect of this drug which is not (in my view) getting as much attention as it deserves.
GLP-1 is a modified 30 amino acid peptide! Yet it is orally active.
1/5
There is an important pharmacological aspect of this drug which is not (in my view) getting as much attention as it deserves.
GLP-1 is a modified 30 amino acid peptide! Yet it is orally active.
1/5
January 6, 2026 at 12:47 AM
supercool small-molecule bioavailability science thread
my bioavailability is through the roof
February 11, 2025 at 12:27 AM
my bioavailability is through the roof
yes but caveat, the bioavailability of the generics suck and you need twice the dosage
April 30, 2024 at 12:18 AM
yes but caveat, the bioavailability of the generics suck and you need twice the dosage
Southern US and Central/South-American alliance to alkalize staple maize for improved vitamin, minerals, and amino acid bioavailability.
April 14, 2025 at 6:13 AM
Southern US and Central/South-American alliance to alkalize staple maize for improved vitamin, minerals, and amino acid bioavailability.
Iron iron everywhere
But none with bioavailability
But none with bioavailability
March 14, 2025 at 8:22 PM
Iron iron everywhere
But none with bioavailability
But none with bioavailability
I wonder if the high sodium does something related to the bioavailability of iron
September 22, 2026 at 11:30 AM
I wonder if the high sodium does something related to the bioavailability of iron
![Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs).](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ifnh47bjqadbg3fl2lqn2cwp/bafkreiac4ljjyzcn66dp7nm3k26z7kftfkbyfncfehkgnxjpbzbbbrpaui)
October 29, 2024 at 4:25 AM
[Food]
"Bioavailability" basically refers to how much work your body has to do to absorb a nutrient
Proteins are long chains/strings of amino acids, all twisted around
Our bodies have to cut them into smaller pieces (e.g. individual amino acids) to absorb them
"Bioavailability" basically refers to how much work your body has to do to absorb a nutrient
Proteins are long chains/strings of amino acids, all twisted around
Our bodies have to cut them into smaller pieces (e.g. individual amino acids) to absorb them
Eating with MCAS: hacking nutrient bioavailability when reintroducing foods
[CN: this post discusses food and nutrition; there are also some hopefully judgement-free metaphors about exercise] A couple years ago, I was talking with my nutritionist about how certain cooking …
liminalnest.wordpress.com
March 6, 2025 at 2:22 PM
[Food]
"Bioavailability" basically refers to how much work your body has to do to absorb a nutrient
Proteins are long chains/strings of amino acids, all twisted around
Our bodies have to cut them into smaller pieces (e.g. individual amino acids) to absorb them
"Bioavailability" basically refers to how much work your body has to do to absorb a nutrient
Proteins are long chains/strings of amino acids, all twisted around
Our bodies have to cut them into smaller pieces (e.g. individual amino acids) to absorb them
If the problem you're having is it wearing off mid-afternoon, it's not just that being the time of highest exposure, it's that diphenhydramine has an "effective level of bioavailability" duration of about 3-4 hours tops but the side effects will linger for a while after the peak bioavailability
March 16, 2024 at 4:22 AM
If the problem you're having is it wearing off mid-afternoon, it's not just that being the time of highest exposure, it's that diphenhydramine has an "effective level of bioavailability" duration of about 3-4 hours tops but the side effects will linger for a while after the peak bioavailability
Many real medicines did start by investigating folk remedies & plants used for healing! Biomedical researchers are very aware that herbs used for healing have active compounds that can be isolated and improved upon (in the artemisinin example: scientists greatly improved its bioavailability)
August 6, 2025 at 11:16 AM
Many real medicines did start by investigating folk remedies & plants used for healing! Biomedical researchers are very aware that herbs used for healing have active compounds that can be isolated and improved upon (in the artemisinin example: scientists greatly improved its bioavailability)