#CCRDownunder
Chief Investigator @darknatter.bsky.social shares insights from the #ADAPTsepsistrial at #CCRdownunder

@adaptsepsis @jama.com
December 10, 2024 at 3:19 AM
A major take home from ADAPT-SEPSIS - docs aren’t as good at stopping antibiotics as we think we are… #ccrdownunder
December 9, 2024 at 10:44 PM
Some images of today's sessions from #CCRdownunder
December 10, 2024 at 6:39 AM
Less than 3 hours to #CCRdownunder in Melbourne

➡️ 8 major trial results over 2 days

➡️ In depth discussions

➡️ Full, free livestream

criticalcarereviews.com
December 9, 2024 at 7:19 PM
Another albumin trial failing to show benefit. A recurring theme across different settings?
#CCRdownunder
December 10, 2024 at 3:19 AM
Looking forward to this one #RENOVATEtrial #CCRdownunder
December 11, 2024 at 12:01 AM
Co-Chief Investigators Mark Dennis and Brian Burns share the findings from the #EVIDENCEtrial at #CCRdownunder
December 11, 2024 at 5:55 AM
Published in JAMA with #CCRdownunder:

In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @criticalcarereviews.com

ja.ma/3BovM5v
December 9, 2024 at 10:20 PM
RSI trial now starting

➡️ Etomidate vs Ketamine for RSI

➡️ Jonathan Casey & Matthew Semler presenting
➡️ Chris Nickson editorialising

➡️ Join the livestream - criticalcarereviews.com

#ccrdownunder
December 10, 2025 at 12:14 AM
#CCRdownunder Day 1 done!
December 10, 2024 at 7:57 AM
Congratulations to the RSI trial team #CCRdownunder
nejm.org NEJM.org @nejm.org · Dec 10
In a randomized trial involving critically ill patients undergoing intubation in EDs or ICUs, the use of ketamine for the induction of anesthesia did not lead to significantly lower in-hospital mortality than etomidate. Full trial results: nej.md/44EOlxB

@criticalcarereviews.com
December 10, 2025 at 12:34 AM
The stepped wedge design came up in the #CCRDownUnder meeting last week so it seemed a good time to revisit the pros and cons of this design 1/6
#MethodologyMonday #128
December 15, 2025 at 8:05 AM
#CCRdownunder attendees, check out these findings from this year's @criticalcarereviews.com meeting 🧵:

In critically ill adults w/ suspected sepsis, antibiotic regimens were reduced when guided by measurement of procalcitonin but not by C-reactive protein. ja.ma/49BSvrC
December 11, 2024 at 6:24 AM
Ganga Giri delivers an amazing opening performance at the Edge

#CCRdownunder
December 10, 2024 at 5:59 AM
All set for inaugural #ccrdownunder
4 major trial results coming up…
December 9, 2024 at 9:28 PM
Chief Investigator Shane English and Senior Investigator Anthony Delaney share their findings from the #SAHaRAtrial at #CCRdownunder
December 10, 2024 at 7:56 AM
High-flow nasal oxygen was noninferior to noninvasive ventilation for rates of endotracheal intubation or death within 7 days in 4 of the 5 patient groups with acute respiratory failure.

#CCRdownunder @criticalcarereviews.com

ja.ma/41s0Lbx
December 11, 2024 at 12:20 AM
Chief Investigator Manu Shankar-Hari shares the findings from the #VACIRiSStrial at #CCRdownunder
December 10, 2024 at 5:27 AM
Co-Chief Investigators Brenda O'Neill and Danny McAuley share the results of the #iRehab trial after presenting at #CCRdownunder

Livestream -> www.criticalcarereviews.com

@jama.com
December 9, 2025 at 7:17 AM
December 10, 2024 at 5:03 AM
Presented at #CCRDownUnder:

In the SAHARA trial involving patients with subarachnoid hemorrhage and anemia, liberal transfusion of red cells did not result in a lower risk of an unfavorable neurologic outcome than a more restrictive strategy. nej.md/4ilTVdO
December 10, 2024 at 12:39 PM
Summary and conclusions

#CCRdownunder
#CCRdownunder24
December 10, 2024 at 12:30 AM
RENOVATE trial

HFNC therapy versus non-invasive positive pressure ventilation in acute respiratory failure 

Prof Israel Maia presents the results from CCR Down Under in Melbourne. 

#CCRdownunder
December 11, 2024 at 12:24 AM