SRI-filtered stock screening report for September 23, 2026. Daily signals with technical analysis and sentiment.

Accurate variant detection using nanopore long-read transcriptome data remains challenging. Here we present NanoTS-a deep learning-based tool for single nucleotide polymorphism detection from diverse types of nanopore transcriptome sequencing data. NanoTS outperforms existing methods, achieving F(1) scores above 0.980 and 0.966 on nanopore direct RNA and cDNA sequencing data, respectively, for single nucleotide polymorphisms with at least five supporting reads. Notably, NanoTS shows strong...

Alt: JFK's Iconic 'I Like Your Funny Words, Magic Man' Meme from the show Clone High

Abstract. One of the main challenges of whole transcriptome sequencing is the difficulty in detecting and quantifying low-to-moderate abundance transcripts

Article de RNA-Seq Blog

SRI-filtered stock screening report for September 14, 2026. Daily signals with technical analysis and sentiment.

Descriptive, non-directional summary of recent AI analyses.

The Cdna Clone Vector Market Industry is expected to grow from 0.15(USD Billion) in 2024 to 0.2 (USD Billion) by 2032. The Cdna Clone Vector Market CAGR (growth rate) is expected to be around 4.01% | ...

The method described here allows the efficient generation of a series of different human-like glycoforms at large homogeneity of virtually any antibody within one week after cDNA delivery to plants. This accelerates follow up functional studies and thus may contribute to study the biological role of …

SRI-filtered stock screening report for September 10, 2026. Daily signals with technical analysis and sentiment.

SRI-filtered stock screening report for September 4, 2026. Daily signals with technical analysis and sentiment.

Oxford Nanopore Technology (ONT) direct RNA sequencing enables the sequencing of native RNA molecules without cDNA conversion. The long-read approach captures full-length reads spanning entire genes and has transformed the study of gene expression in #Plasmodium parasites by enabling analysis of untranslated regions, isoforms, and alternative splicing. In addition, ONT provides unique insights into non-coding RNAs, RNA modifications, and polyadenylated tail dynamics, which are expanding our understanding of post-transcriptional regulation in #Plasmodium, including processes beyond translational repression in gametocytes and sporozoites. Here, we discuss the past and future applications of direct RNA sequencing in #Plasmodium research and highlight its advantages, limitations, and future prospects.

Oxford Nanopore Technology (ONT) direct RNA sequencing enables the sequencing of native RNA molecules without cDNA conversion. The long-read approach captures full-length reads spanning entire genes and has transformed the study of gene expression in #Plasmodium parasites by enabling analysis of untranslated regions, isoforms, and alternative splicing. In addition, ONT provides unique insights into non-coding RNAs, RNA modifications, and polyadenylated tail dynamics, which are expanding our understanding of post-transcriptional regulation in #Plasmodium, including processes beyond translational repression in gametocytes and sporozoites. Here, we discuss the past and future applications of direct RNA sequencing in #Plasmodium research and highlight its advantages, limitations, and future prospects.

Oxford Nanopore Technology (ONT) direct RNA sequencing enables the sequencing of native RNA molecules without cDNA conversion. The long-read approach captures full-length reads spanning entire genes and has transformed the study of gene expression in Plasmodium parasites by enabling analysis of untranslated regions, isoforms, and alternative splicing. In addition, ONT provides unique insights into non-coding RNAs, RNA modifications, and polyadenylated tail dynamics, which are expanding our understanding of post-transcriptional regulation in Plasmodium, including processes beyond translational repression in gametocytes and sporozoites. Here, we discuss the past and future applications of direct RNA sequencing in Plasmodium research and highlight its advantages, limitations, and future prospects.

a, SpcR E. coli SQ110DTC3R cells transformed with pRibo-M(HB) or pRibo-M(GFP) plasmids were grown in the absence or presence of 1 mg/ml of Spc. The ratio between native 16S rRNA and mrRNA in the total ribosome preparation was analysed by primer extension making use of the SpcR mutation C1192U present in the native SQ110DTC3R ribosomes. RNA samples prepared from wild type (WT) ribosomes and from ribosomes from untransformed SQ110DTC3R cells (SpcR) were used to generate cDNA markers. b, Quantification of gels originated from two independent experiments; one of them is shown in panel (a). n = 2 biologically independent samples. Experimental values are shown by dots; bars represent experimental mean. Statistical significance of the difference between the samples was assessed by unpaired t-test with Welch’s correction. c, Growth of cells transformed with pRibo-M(GFP) or a control plasmid pAMB expressing the wt rrnB operon. n = 5 biologically independent samples. Coloured dots show mean experimental values; error bars show SD. Doubling time (τ) was calculated in GraphPad Prism using the logarithmic phase of the growth curve (40–90 min). d, Fluorescence (λex = 488, λem = 520) of BL21 cells transformed with pRibo-M(GFP) after an overnight growth (“0”) or passaged for 30...