Evolutionary therapy (ET) needs accurate tumour burden tracking.
"RECIST misses disease progression by months and ET must be guided by 3D measurements"
@katstankova.bsky.social @tpmtudelft.bsky.social @erasmusmc.bsky.social #erasmus #cancerevolution
doi.org/10.1093/jeb/...
"RECIST misses disease progression by months and ET must be guided by 3D measurements"
@katstankova.bsky.social @tpmtudelft.bsky.social @erasmusmc.bsky.social #erasmus #cancerevolution
doi.org/10.1093/jeb/...
Enabling evolutionary therapy in metastatic cancer lacking serum biomarkers
Abstract. Evolutionary therapy (ET) aims to anticipate and steer tumour evolution by adjusting treatment timing and dosing, often to control rather than er
doi.org
September 24, 2026 at 8:44 AM
Evolutionary therapy (ET) needs accurate tumour burden tracking.
"RECIST misses disease progression by months and ET must be guided by 3D measurements"
@katstankova.bsky.social @tpmtudelft.bsky.social @erasmusmc.bsky.social #erasmus #cancerevolution
doi.org/10.1093/jeb/...
"RECIST misses disease progression by months and ET must be guided by 3D measurements"
@katstankova.bsky.social @tpmtudelft.bsky.social @erasmusmc.bsky.social #erasmus #cancerevolution
doi.org/10.1093/jeb/...
Some great talks today on the first full day of #iseec2026 #CancerEvolution, many of them from my Moffitt colleagues talking about cancer ecology and evolution during treatment
May 22, 2026 at 4:27 PM
Some great talks today on the first full day of #iseec2026 #CancerEvolution, many of them from my Moffitt colleagues talking about cancer ecology and evolution during treatment
For those of you here interested in #MathOnco (and maybe #somaticevolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
https://thisweekmathonco.substack.com/
https://thisweekmathonco.substack.com/
November 17, 2024 at 6:30 PM
For those of you here interested in #MathOnco (and maybe #somaticevolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
https://thisweekmathonco.substack.com/
https://thisweekmathonco.substack.com/
Massive thanks to the two brilliant outgoing co-chairs of #CEWG @jeffreytownsend.bsky.social and Anna Barker. Thanks for all you’ve done for the field of #CancerEvolution #AACR25 @theaacr.bsky.social
April 29, 2025 at 10:53 PM
Massive thanks to the two brilliant outgoing co-chairs of #CEWG @jeffreytownsend.bsky.social and Anna Barker. Thanks for all you’ve done for the field of #CancerEvolution #AACR25 @theaacr.bsky.social
How do cells lining our epithelium evolve over a lifetime? 🧬 We built PHYFUM, a new Bayesian phylogenetic method to reconstruct the evolutionary history of normal tissue using Fluctuating Methylation. Here's what we found 👇 #CancerEvolution
doi.org/10.64898/202...
doi.org/10.64898/202...
May 11, 2026 at 4:02 PM
How do cells lining our epithelium evolve over a lifetime? 🧬 We built PHYFUM, a new Bayesian phylogenetic method to reconstruct the evolutionary history of normal tissue using Fluctuating Methylation. Here's what we found 👇 #CancerEvolution
doi.org/10.64898/202...
doi.org/10.64898/202...
Thrilled to share our discovery of novel long-deletion signatures—key markers for tracking #MMRd #CancerEvolution, even in low-pass (~0.1X) FFPE samples with low purity. This was made possible with our tool, MILO, as named by @trevorgraham.bsky.social. Our preprint: www.biorxiv.org/content/10.1...
Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability
Deficiency in the mismatch repair system (MMRd) causes microsatellite instability (MSI) in cancers and determines eligibility for immunotherapy. Here, we show that MMRd tumours harbour long-deletion s...
www.biorxiv.org
October 9, 2024 at 1:22 PM
Thrilled to share our discovery of novel long-deletion signatures—key markers for tracking #MMRd #CancerEvolution, even in low-pass (~0.1X) FFPE samples with low purity. This was made possible with our tool, MILO, as named by @trevorgraham.bsky.social. Our preprint: www.biorxiv.org/content/10.1...
Application deadline for our @wellcometrust.bsky.social #CancerEvolution summer school is tomorrow, 1 April 2025.
coursesandconferences.wellcomeconnectingscience.org/event/evolut...
Our brilliant faculty will cover evo&eco theory, math models, genomics, digital path, clinical trial design & more
coursesandconferences.wellcomeconnectingscience.org/event/evolut...
Our brilliant faculty will cover evo&eco theory, math models, genomics, digital path, clinical trial design & more
March 31, 2025 at 9:50 AM
Application deadline for our @wellcometrust.bsky.social #CancerEvolution summer school is tomorrow, 1 April 2025.
coursesandconferences.wellcomeconnectingscience.org/event/evolut...
Our brilliant faculty will cover evo&eco theory, math models, genomics, digital path, clinical trial design & more
coursesandconferences.wellcomeconnectingscience.org/event/evolut...
Our brilliant faculty will cover evo&eco theory, math models, genomics, digital path, clinical trial design & more
Fluctuating DNA methylation tracks cancer evolution at clinical scale. #DNAmethylation #CancerEvolution #Genomics @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 27, 2025 at 7:05 PM
Fluctuating DNA methylation tracks cancer evolution at clinical scale. #DNAmethylation #CancerEvolution #Genomics @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Excited about today’s @crc1430.bsky.social @unidue.bsky.social talk by Roland Schwarz from the ICCB Cologne, hosted jointly with WTZ!
He will present on: "Inferring clonal evolution in chromosomally unstable tumours."
#ComputationalBiology #CancerGenomics #CancerEvolution
He will present on: "Inferring clonal evolution in chromosomally unstable tumours."
#ComputationalBiology #CancerGenomics #CancerEvolution
November 3, 2025 at 2:52 PM
Excited about today’s @crc1430.bsky.social @unidue.bsky.social talk by Roland Schwarz from the ICCB Cologne, hosted jointly with WTZ!
He will present on: "Inferring clonal evolution in chromosomally unstable tumours."
#ComputationalBiology #CancerGenomics #CancerEvolution
He will present on: "Inferring clonal evolution in chromosomally unstable tumours."
#ComputationalBiology #CancerGenomics #CancerEvolution
Learn about the genetic and non-genetic mechanisms of #CancerEvolution at the EMBO Workshop "The Many Faces of Cancer Evolution" in #Rimini, #Italy, 27–29 May 2026.
Registration deadline: 10 May 2026
https://meetings.embo.org/event/26-cancer-evo
#EMBOCancerEvolution #EMBOevents 🧪
Registration deadline: 10 May 2026
https://meetings.embo.org/event/26-cancer-evo
#EMBOCancerEvolution #EMBOevents 🧪
April 29, 2026 at 6:11 AM
Learn about the genetic and non-genetic mechanisms of #CancerEvolution at the EMBO Workshop "The Many Faces of Cancer Evolution" in #Rimini, #Italy, 27–29 May 2026.
Registration deadline: 10 May 2026
https://meetings.embo.org/event/26-cancer-evo
#EMBOCancerEvolution #EMBOevents 🧪
Registration deadline: 10 May 2026
https://meetings.embo.org/event/26-cancer-evo
#EMBOCancerEvolution #EMBOevents 🧪
We welcome applicants with expertise in the #biology of #SolidCancers, #TumourImmunology, #CancerEvolution, & computational/ #ML approaches to #tumour ecosystems; but we encourage visionary proposals from across the spectrum of #CancerResearch that complement & expand our existing strengths
#CanSky
#CanSky
New Group Leader Recruitment Now Open (MI/25/54) | Cancer Research UK Manchester Institute
We are seeking to appoint exceptional early-career scientists, including clinician scientists, as Group Leaders to develop bold, innovative, and high-impact research programmes.
www.cruk.manchester.ac.uk
September 24, 2025 at 3:03 PM
We welcome applicants with expertise in the #biology of #SolidCancers, #TumourImmunology, #CancerEvolution, & computational/ #ML approaches to #tumour ecosystems; but we encourage visionary proposals from across the spectrum of #CancerResearch that complement & expand our existing strengths
#CanSky
#CanSky
Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm <a href="http://www.vanbug.org/2019/quaid-morris-2/" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!
Redirecting...
www.vanbug.org
November 18, 2024 at 3:08 PM
Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm <a href="http://www.vanbug.org/2019/quaid-morris-2/" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!
Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm <a href="http://www.vanbug.org/2019/quaid-morris-2/" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!
Redirecting...
www.vanbug.org
November 16, 2024 at 4:11 PM
Tired of the #NeurIPS grind? Come see me speak about #cancerevolution at @VanBUG_ this Thursday at 6pm <a href="http://www.vanbug.org/2019/quaid-morris-2/" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.vanbug.org/2019/quaid-morris-2/ BC cancer agency isn’t THAT far away, you should see more of Vancouver!
6/Behind-the-scenes blog coming this weekend: the journey, challenges, and the 🍷 analogy that started it all in 2019. #CancerGenomics #CancerEvolution #ComputationalBiology
Code and resources:
🧬 SelectSim:
github.com/CSOgroup/Sel...
📄 Paper:
www.nature.com/articles/s41...
Code and resources:
🧬 SelectSim:
github.com/CSOgroup/Sel...
📄 Paper:
www.nature.com/articles/s41...
Evolving patterns of co-mutations from tumor initiation to metastatic progression - Nature Genetics
SelectSim uses cancer and healthy tissue sequencing datasets to identify co-mutations that occur more or less frequently than would be expected by chance. Differences in co-mutation patterns observed ...
www.nature.com
July 10, 2026 at 10:56 PM
6/Behind-the-scenes blog coming this weekend: the journey, challenges, and the 🍷 analogy that started it all in 2019. #CancerGenomics #CancerEvolution #ComputationalBiology
Code and resources:
🧬 SelectSim:
github.com/CSOgroup/Sel...
📄 Paper:
www.nature.com/articles/s41...
Code and resources:
🧬 SelectSim:
github.com/CSOgroup/Sel...
📄 Paper:
www.nature.com/articles/s41...
13/n This was a dream postdoc project — the kind that kept me up late, but lit me up inside.
I grew immensely as a scientist, piecing together fragments of cancer evolution and immune microenvironment. Proud to share what we uncovered
#postdoclife #cancerevolution #GynOncol
I grew immensely as a scientist, piecing together fragments of cancer evolution and immune microenvironment. Proud to share what we uncovered
#postdoclife #cancerevolution #GynOncol
June 16, 2025 at 5:49 PM
13/n This was a dream postdoc project — the kind that kept me up late, but lit me up inside.
I grew immensely as a scientist, piecing together fragments of cancer evolution and immune microenvironment. Proud to share what we uncovered
#postdoclife #cancerevolution #GynOncol
I grew immensely as a scientist, piecing together fragments of cancer evolution and immune microenvironment. Proud to share what we uncovered
#postdoclife #cancerevolution #GynOncol
We are recruiting a postdoc to join our team (myself, Boris Bastian, and Iwei Yeh) at UCSF to develop a pre-cancer atlas of skin cancer -- part of the Human Tumor Atlas Network (#HTAN). #CancerEvolution #Bioinformatics. Interested? Email resume and cover letter to me.
December 14, 2024 at 5:43 PM
We are recruiting a postdoc to join our team (myself, Boris Bastian, and Iwei Yeh) at UCSF to develop a pre-cancer atlas of skin cancer -- part of the Human Tumor Atlas Network (#HTAN). #CancerEvolution #Bioinformatics. Interested? Email resume and cover letter to me.
IICD is pleased to host Dr. Andrea Sottoriva from @humantechnopole.bsky.social for the next event in our Seminar Series.
Register > bit.ly/4aJsMys
#MachineLearning #PopulationGenetics #CancerEvolution #CancerResearch @columbiacancer.bsky.social @nygenome.org
Register > bit.ly/4aJsMys
#MachineLearning #PopulationGenetics #CancerEvolution #CancerResearch @columbiacancer.bsky.social @nygenome.org
March 26, 2026 at 1:42 PM
IICD is pleased to host Dr. Andrea Sottoriva from @humantechnopole.bsky.social for the next event in our Seminar Series.
Register > bit.ly/4aJsMys
#MachineLearning #PopulationGenetics #CancerEvolution #CancerResearch @columbiacancer.bsky.social @nygenome.org
Register > bit.ly/4aJsMys
#MachineLearning #PopulationGenetics #CancerEvolution #CancerResearch @columbiacancer.bsky.social @nygenome.org
Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution
October 28, 2025 at 9:59 PM
Great didactic at #MathOnco25 by @dwodarz.bsky.social showing the importance of space...and turnover in #cancerevolution
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com
thisweekmathonco.substack.com
This week in Mathematical Oncology | Jeffrey West | Substack
"This week in Mathematical Oncology" -- the weekly email newsletter. Click to read This week in Mathematical Oncology, by Jeffrey West, a Substack publication with thousands of subscribers.
thisweekmathonco.substack.com
November 17, 2024 at 4:50 PM
For those of you here interested in #MathOnco (and maybe #SomaticEvolution #CancerEvolution) this is an important resource, and since it is a newsletter you can keep up to date with the field whether you are here or twitter (or any other site):
thisweekmathonco.substack.com
thisweekmathonco.substack.com
What a week at the Field's discussing #MathOnco and #CancerEvolution / #CancerEcology. Thanks Jasmine Foo and Dominik Wodarz for organizing! and Thomas Hillen too!
October 4, 2024 at 10:28 PM
What a week at the Field's discussing #MathOnco and #CancerEvolution / #CancerEcology. Thanks Jasmine Foo and Dominik Wodarz for organizing! and Thomas Hillen too!
Happy to join Mathematical Biosciences as an editorial board member. I am hoping to bring my expertise in #AgentBasedModels and #EvolutionaryGameTheory to model #CancerEvolution and #TreatmentResistance in the context of #Ecology
www.sciencedirect.com/journal/math...
www.sciencedirect.com/journal/math...
Mathematical Biosciences | Journal | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of Mathematical Biosciences at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
March 14, 2024 at 5:48 PM
Happy to join Mathematical Biosciences as an editorial board member. I am hoping to bring my expertise in #AgentBasedModels and #EvolutionaryGameTheory to model #CancerEvolution and #TreatmentResistance in the context of #Ecology
www.sciencedirect.com/journal/math...
www.sciencedirect.com/journal/math...
Planning my trip to #AACRevol23 #CancerEvolution in Boston next month, who else is coming?
www.aacr.org/meeting/aacr...
www.aacr.org/meeting/aacr...
AACR Special Conference in Cancer Research: Translating Cancer Evolution and Data Science: The Next ...
In association with the Cancer Evolution Working Group December 3-6, 2023Westin Copley PlaceBoston, Massachusetts Conference cochairs Anna D. Barker, Ellison Institute for Transformative Medicine of U...
www.aacr.org
November 15, 2023 at 3:04 AM
Planning my trip to #AACRevol23 #CancerEvolution in Boston next month, who else is coming?
www.aacr.org/meeting/aacr...
www.aacr.org/meeting/aacr...
Inspiring presentation at #MoffittCancerCenter today by Baylor's Susan M. Rosenberg talking about #cancerEvolution BUT looking at something less common: the DNA damageone and how extrinsic elements change a tumor cell's mutation rate and thus key features of #cancer #evolution
October 4, 2023 at 7:29 PM
Inspiring presentation at #MoffittCancerCenter today by Baylor's Susan M. Rosenberg talking about #cancerEvolution BUT looking at something less common: the DNA damageone and how extrinsic elements change a tumor cell's mutation rate and thus key features of #cancer #evolution
For my first post here I will introduce myself: I am a mathematical oncologist (#MathOnco) at the Integrated Mathematical Oncology dept (@mathonco.bsky.social ) at the Moffitt Cancer Center in FL working on #CancerEvolution and #CancerEcology hoping to understand how cancers evolve over time
September 24, 2023 at 3:14 PM
For my first post here I will introduce myself: I am a mathematical oncologist (#MathOnco) at the Integrated Mathematical Oncology dept (@mathonco.bsky.social ) at the Moffitt Cancer Center in FL working on #CancerEvolution and #CancerEcology hoping to understand how cancers evolve over time