Understanding Cartilage Damage: Impact on Joint Health and Mobility

Learn how cartilage wear and tear affects your joints, leading to pain, stiffness, and reduced mobility, and explore practical ways to protect your joint health.
#CartilageDamage #JointHealth https://www.rfr.bz/b5b641a2a

Restoring joint #homeostasis could transform #osteoarthritis care.
This review explores how purinergic P2 and P1 receptor signalling drives #CartilageDamage and pain, highlighting new targets for precision therapies.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

#Periostin (#POSTN) drives #ChondrocyteHypertrophy and #osteoarthritis progression via #RUNX2 signaling, with its inhibition reducing #CartilageDamage, and hypertrophic gene expression, highlighting it as a therapeutic target for OA management.
#OpenAccess: doi.org/10.1016/j.ge...