Thank you @sarponggroup.bsky.social #ChemCollabs
August 21, 2025 at 3:17 PM
Thank you @sarponggroup.bsky.social #ChemCollabs
Tert-butylamine as a labile ligand and base enables cross-coupling reactions with various nucleophile classes. A great collaboration of Jonas with the Sigman lab and Gschwind group
#ChemSky #ChemCollabs #photocatalysis
doi.org/10.1021/acsc...
#ChemSky #ChemCollabs #photocatalysis
doi.org/10.1021/acsc...
Cross-Coupling Reactions with Nickel, Visible Light, and tert-Butylamine as a Bifunctional Additive
Transition metal catalysis is crucial for the synthesis of complex molecules, with ligands and bases playing a pivotal role in optimizing cross-coupling reactions. Despite advancements in ligand desig...
doi.org
January 16, 2025 at 4:16 PM
Tert-butylamine as a labile ligand and base enables cross-coupling reactions with various nucleophile classes. A great collaboration of Jonas with the Sigman lab and Gschwind group
#ChemSky #ChemCollabs #photocatalysis
doi.org/10.1021/acsc...
#ChemSky #ChemCollabs #photocatalysis
doi.org/10.1021/acsc...
This divergent cross coupling paper in #JACS from @reiswoman.bsky.social Reisman lab @CalTech with the Sigman lab @ Utah with #Amgen is really neat
Differential coupling products from anhydrides - nice #ChemCollabs work everyone
Differential coupling products from anhydrides - nice #ChemCollabs work everyone
Ni-Catalyzed Enantioselective Desymmetrization: Development of Divergent Acyl and Decarbonylative Cross-Coupling Reactions
Ni-catalyzed asymmetric reductive cross-coupling reactions provide rapid and modular access to enantioenriched building blocks from simple electrophile precursors. Reductive coupling reactions that ca...
pubs.acs.org
January 14, 2025 at 5:46 PM
This divergent cross coupling paper in #JACS from @reiswoman.bsky.social Reisman lab @CalTech with the Sigman lab @ Utah with #Amgen is really neat
Differential coupling products from anhydrides - nice #ChemCollabs work everyone
Differential coupling products from anhydrides - nice #ChemCollabs work everyone
1/n - #12DaysofPapers
Highlighting this #PfizerChemistry #ChemCollabs with the Szymczyk Lab @ Michigan Chem enabling C-H coupling of fluoroalkyls with vinyl-BPins to access some really neat complex fragments ready for additional functionalization
pubs.rsc.org/en/content/a...
Highlighting this #PfizerChemistry #ChemCollabs with the Szymczyk Lab @ Michigan Chem enabling C-H coupling of fluoroalkyls with vinyl-BPins to access some really neat complex fragments ready for additional functionalization
pubs.rsc.org/en/content/a...
A metal-free strategy to construct fluoroalkyl–olefin linkages using fluoroalkanes
We present a metal-free strategy to access fluoroalkyl–olefin linkages from fluoroalkane precursors and vinyl-pinacol boronic ester (BPin) reagents. This reaction sequence is templated by the boron re...
pubs.rsc.org
December 10, 2024 at 12:00 AM
1/n - #12DaysofPapers
Highlighting this #PfizerChemistry #ChemCollabs with the Szymczyk Lab @ Michigan Chem enabling C-H coupling of fluoroalkyls with vinyl-BPins to access some really neat complex fragments ready for additional functionalization
pubs.rsc.org/en/content/a...
Highlighting this #PfizerChemistry #ChemCollabs with the Szymczyk Lab @ Michigan Chem enabling C-H coupling of fluoroalkyls with vinyl-BPins to access some really neat complex fragments ready for additional functionalization
pubs.rsc.org/en/content/a...
Starting off 2025 pretty well - new #ChemCollabs paper about to hit #ChemRxiv with a pretty cool new reaction under optimization
And some neat chemistry on [REDACTED] project
And the @organicdivision.org ORGN program for #ACSSpring2025 is going to be excellent!
And some neat chemistry on [REDACTED] project
And the @organicdivision.org ORGN program for #ACSSpring2025 is going to be excellent!
January 19, 2025 at 3:20 PM
Starting off 2025 pretty well - new #ChemCollabs paper about to hit #ChemRxiv with a pretty cool new reaction under optimization
And some neat chemistry on [REDACTED] project
And the @organicdivision.org ORGN program for #ACSSpring2025 is going to be excellent!
And some neat chemistry on [REDACTED] project
And the @organicdivision.org ORGN program for #ACSSpring2025 is going to be excellent!
10/ #12DaysofPapers #ChemSky
Presenting some of my favorite #PfizerChemistry papers from 2024
Next up is a multi-center #ChemCollabs from our Groton and La Jolla labs with @shenvi.bsky.social, the Baran lab and #Biogen out in @science.org forming tertiary sp3 centers from RAEs or olefins
Presenting some of my favorite #PfizerChemistry papers from 2024
Next up is a multi-center #ChemCollabs from our Groton and La Jolla labs with @shenvi.bsky.social, the Baran lab and #Biogen out in @science.org forming tertiary sp3 centers from RAEs or olefins
Carbon quaternization of redox active esters and olefins by decarboxylative coupling
The synthesis of quaternary carbons often requires numerous steps and complex conditions or harsh reagents that act on heavily engineered substrates. This is largely a consequence of conventional pola...
www.science.org
December 17, 2024 at 7:11 PM
10/ #12DaysofPapers #ChemSky
Presenting some of my favorite #PfizerChemistry papers from 2024
Next up is a multi-center #ChemCollabs from our Groton and La Jolla labs with @shenvi.bsky.social, the Baran lab and #Biogen out in @science.org forming tertiary sp3 centers from RAEs or olefins
Presenting some of my favorite #PfizerChemistry papers from 2024
Next up is a multi-center #ChemCollabs from our Groton and La Jolla labs with @shenvi.bsky.social, the Baran lab and #Biogen out in @science.org forming tertiary sp3 centers from RAEs or olefins
Join Chemistry & Food Tuesdays tomorrow with guest, Daniel Corey, Ph.D. (Fehl Lab alum). Daniel’s talk will focus on the importance of collaboration and community in science. #wsuchemistry #chemcollabs #chemtalk
See you there ⬇️
Tuesday, February 18th, 12:30-1:30 pm, room 111, Chemistry
See you there ⬇️
Tuesday, February 18th, 12:30-1:30 pm, room 111, Chemistry
February 17, 2025 at 5:33 PM
Join Chemistry & Food Tuesdays tomorrow with guest, Daniel Corey, Ph.D. (Fehl Lab alum). Daniel’s talk will focus on the importance of collaboration and community in science. #wsuchemistry #chemcollabs #chemtalk
See you there ⬇️
Tuesday, February 18th, 12:30-1:30 pm, room 111, Chemistry
See you there ⬇️
Tuesday, February 18th, 12:30-1:30 pm, room 111, Chemistry
2/n #12DaysofPapers #ChemSky I’m a big fan of S(VI) and excited to see the #ChemCollabs continue between #PfizerChemistry and the Willis Lab @rhpdcu.bsky.social at Oxford including this facile Cu-catalyzed access to sulfinates using SMOPS - one of the best reagent names pubs.acs.org/doi/10.1021/...
December 10, 2024 at 3:28 PM
2/n #12DaysofPapers #ChemSky I’m a big fan of S(VI) and excited to see the #ChemCollabs continue between #PfizerChemistry and the Willis Lab @rhpdcu.bsky.social at Oxford including this facile Cu-catalyzed access to sulfinates using SMOPS - one of the best reagent names pubs.acs.org/doi/10.1021/...
4a/ #12DaysofPapers #ChemSky. This 2024 favorite is a #PfizerChemistry collab with the Weix (Wisconsin) and Sigman (Utah) labs towards computationally designed ligands for Ni-catalyzed cross electrophile coupling. Improvements in selectivity up to 300% #ChemCollabs
Computational Methods Enable the Prediction of Improved Catalysts for Nickel-Catalyzed Cross-Electrophile Coupling
Cross-electrophile coupling has emerged as an attractive and efficient method for the synthesis of C(sp2)–C(sp3) bonds. These reactions are most often catalyzed by nickel complexes of nitrogenous liga...
pubs.acs.org
December 11, 2024 at 7:26 PM
4a/ #12DaysofPapers #ChemSky. This 2024 favorite is a #PfizerChemistry collab with the Weix (Wisconsin) and Sigman (Utah) labs towards computationally designed ligands for Ni-catalyzed cross electrophile coupling. Improvements in selectivity up to 300% #ChemCollabs
The 2H-tautomer of indazole absorbs light more strongly than the 1H-tautomer at longer wavelengths
#ChemSky #chemcollabs
#ChemSky #chemcollabs
Congrats to Logan, Sojung, Yusuke and collaborators from the Barner-Kowollik group, Gilead, and Merck on our indazole to benzimidazole conversion onlinelibrary.wiley.com/doi/10.1002/...
coordinated with the Leonori group onlinelibrary.wiley.com/doi/10.1002/...
coordinated with the Leonori group onlinelibrary.wiley.com/doi/10.1002/...
Phototransposition of Indazoles to Benzimidazoles: Tautomer‐Dependent Reactivity, Wavelength Dependence, and Continuous Flow Studies
Herein, we report a detailed investigation of the photomediated transformation of indazoles to benzimidazoles through a nitrogen-carbon transposition. This phototransposition is known to occur in low....
onlinelibrary.wiley.com
February 6, 2025 at 1:09 PM
The 2H-tautomer of indazole absorbs light more strongly than the 1H-tautomer at longer wavelengths
#ChemSky #chemcollabs
#ChemSky #chemcollabs